ABOUT THE SPEAKER
Stewart Brand - Environmentalist, futurist
Since the counterculture '60s, Stewart Brand has been creating our internet-worked world. Now, with biotech accelerating four times faster than digital technology, Stewart Brand has a bold new plan ...

Why you should listen

With biotech accelerating four times faster than digital technology, the revival of extinct species is becoming possible. Stewart Brand plans to not only bring species back but restore them to the wild.

Brand is already a legend in the tech industry for things he’s created: the Whole Earth Catalog, The WELL, the Global Business Network, the Long Now Foundation, and the notion that “information wants to be free.” Now Brand, a lifelong environmentalist, wants to re-create -- or “de-extinct” -- a few animals that’ve disappeared from the planet.

Granted, resurrecting the woolly mammoth using ancient DNA may sound like mad science. But Brand’s Revive and Restore project has an entirely rational goal: to learn what causes extinctions so we can protect currently endangered species, preserve genetic and biological diversity, repair depleted ecosystems, and essentially “undo harm that humans have caused in the past.”

More profile about the speaker
Stewart Brand | Speaker | TED.com
TED2013

Stewart Brand: The dawn of de-extinction. Are you ready?

史都华.布兰德(Stewart Brand): 终止灭绝的黎明。你准备好了吗?

Filmed:
2,072,185 views

纵贯人类历史,我们造成许多生物相继灭亡:侯鸽、东美洲豹、度度鸟⋯⋯。但现在,史都华.布兰德(Stewart Brand)说我们拥有足够科技(和生物学)可以将这些曾被人类赶尽杀绝的动物复活。我们该怎么做呢?从谁开始?他这大哉问的答案可能比你我猜测的更加立即可行。
- Environmentalist, futurist
Since the counterculture '60s, Stewart Brand has been creating our internet-worked world. Now, with biotech accelerating four times faster than digital technology, Stewart Brand has a bold new plan ... Full bio

Double-click the English transcript below to play the video.

00:16
Now, extinction灭绝 is a different不同 kind of death死亡.
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目前,灭种是另一种形式的死亡
00:21
It's bigger.
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规模甚至更大
00:24
We didn't really realize实现 that until直到 1914,
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而我们人类直到1914年
00:27
when the last passenger乘客 pigeon鸽子, a female named命名 Martha玛莎,
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当最后一只名为玛莎的母北美候鸽
00:30
died死亡 at the Cincinnati辛辛那提 zoo动物园.
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死于辛辛那提动物园时 我们才惊觉这点
00:33
This had been the most abundant丰富 bird in the world世界
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牠们曾是世上数量最多的鸟类
00:37
that'd那会 been in North America美国 for six million百万 years年份.
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在北美洲存活了六百万年
00:40
Suddenly突然 it wasn't here at all.
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突然间就这么消逝了
00:44
Flocks鸡群 that were a mile英里 wide and 400 miles英里 long
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牠们曾是一英里宽,四百英里长的群体
00:48
used to darken变暗 the sun太阳.
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还能够遮蔽太阳
00:51
Aldo阿尔 Leopold利奥波德 said this was a biological生物 storm风暴,
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奥尔多•利奥波德说过:“这是一场生物风暴”
00:54
a feathered羽毛 tempest暴风雨.
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“一场羽毛风暴”
00:56
And indeed确实 it was a keystone拱心石 species种类
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而牠们的确是关键物种
00:59
that enriched丰富 the entire整个 eastern deciduous落叶 forest森林,
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使整个东部的落叶林更加丰盛
01:03
from the Mississippi密西西比州 to the Atlantic大西洋,
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从密西西比河到大西洋
01:05
from Canada加拿大 down to the Gulf海湾.
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从加拿大往下至墨西哥湾
01:08
But it went from five billion十亿 birds鸟类 to zero in just a couple一对 decades几十年.
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但就在短短数十年间 数量便从五十亿骤降至零
01:12
What happened发生?
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发生了什么?
01:13
Well, commercial广告 hunting狩猎 happened发生.
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嗯,是因为商业狩猎的开始
01:15
These birds鸟类 were hunted猎杀 for meat that was sold出售 by the ton,
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牠们被捕捉 身上的肉数以吨计地被贩售
01:19
and it was easy简单 to do because when those big flocks成群
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这并不困难,因为当牠们一大群飞降地面时
01:21
came来了 down to the ground地面, they were so dense稠密
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会十分稠密地聚在一起
01:24
that hundreds数以百计 of hunters猎人 and netters网渔船 could show显示 up
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上百位猎人及网子此时一出动
01:26
and slaughter屠宰 them by the tens of thousands数千.
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就扑杀成千上百的旅鸽
01:29
It was the cheapest最便宜 source资源 of protein蛋白 in America美国.
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牠们曾是美洲最便宜的蛋白质来源
01:32
By the end结束 of the century世纪, there was nothing left
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在上个世纪结束时,牠们已经一无所剩
01:34
but these beautiful美丽 skins in museum博物馆 specimen标本 drawers抽屉.
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除了牠们美丽的皮羽还保存在博物馆标本抽屉里
01:39
There's an upside上边 to the story故事.
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故事还有积极的另一面
01:41
This made制作 people realize实现 that the same相同 thing
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它让人们了解同样一件事情
01:43
was about to happen发生 to the American美国 bison野牛,
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即将发生在美洲水牛身上
01:45
and so these birds鸟类 saved保存 the buffalos水牛.
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这样,这些鸟倒是救了水牛一命
01:49
But a lot of other animals动物 weren't saved保存.
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但是,很多其他动物并未被保留下来
01:50
The Carolina卡罗来纳州 parakeet多嘴的人 was a parrot鹦鹉 that lit发光的 up backyards后院 everywhere到处.
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卡罗来纳鹦鹉是是一种曾点缀了家家户户后院的鹦鹉。
01:55
It was hunted猎杀 to death死亡 for its feathers羽毛.
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因为牠自身华美的羽毛而被猎捕致死
01:57
There was a bird that people liked喜欢 on the East Coast called the heath健康 hen母鸡.
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有一种东海岸的鸟,人们喜欢称为松鸡
02:00
It was loved喜爱. They tried试着 to protect保护 it. It died死亡 anyway无论如何.
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外表十分惹人怜爱
人们尝试着去保护他们,然而牠还是绝迹了
02:03
A local本地 newspaper报纸 spelled拼写 out, "There is no survivor幸存者,
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一家当地报纸阐明着,牠们一只不剩
02:07
there is no future未来, there is no life to be recreated重建 in this form形成 ever again."
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世界再也没办法创造出这样的生命。
02:12
There's a sense of deep tragedy悲剧 that goes with these things,
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当物种消失时,总是有种深沉的哀伤蔓延
02:14
and it happened发生 to lots of birds鸟类 that people loved喜爱.
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许多受人喜爱的鸟类已遭此命运
02:17
It happened发生 to lots of mammals哺乳动物.
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同样状况也发生在许多哺乳动物身上
02:19
Another另一个 keystone拱心石 species种类 is a famous著名 animal动物
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另一个关键物种是种有名的动物
02:22
called the European欧洲的 aurochs野牛.
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欧洲野牛
02:24
There was sort分类 of a movie电影 made制作 about it recently最近.
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最近还有部关于牠们的电影
02:26
And the aurochs野牛 was like the bison野牛.
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这些野牛很像水牛
02:29
This was an animal动物 that basically基本上 kept不停 the forest森林
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基本上,这种动物的生态功能
02:32
mixed with grasslands草原 across横过 the entire整个 Europe欧洲 and Asian亚洲 continent大陆,
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使得欧亚大陆的森林之间保有草原
02:37
from Spain西班牙 to Korea韩国.
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从西班牙一直延伸到韩国
02:39
The documentation文件 of this animal动物 goes back
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而人类关于这种动物的记载
02:41
to the Lascaux拉斯科 cave洞穴 paintings绘画.
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可以回溯到拉斯科岩洞画的年代
02:45
The extinctions灭绝 still go on.
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许多动物仍陆续灭绝
02:47
There's an ibex山羊 in Spain西班牙 called the bucardoBucardo这.
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一种分布在西班牙,名为布卡多山羊的野山羊
02:50
It went extinct绝种 in 2000.
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于2000年灭绝
02:52
There was a marvelous奇妙 animal动物, a marsupial有袋动物 wolf
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也有一些令人惊叹的物种,像是袋狼
02:55
called the thylacine袋狼 in Tasmania塔斯马尼亚, south of Australia澳大利亚,
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他们在澳洲的塔斯马尼亚州
02:59
called the Tasmanian塔斯马尼亚 tiger.
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又称塔斯马尼亚狼或塔斯马尼亚虎
03:01
It was hunted猎杀 until直到 there were just a few少数 left to die in zoos动物园.
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他们也逃不过猎杀,最后几只在动物园中死去
03:05
A little bit of film电影 was shot射击.
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这是一小段影片
03:19
Sorrow悲哀, anger愤怒, mourning.
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沉重、愤怒、悲伤
03:24
Don't mourn. Organize组织.
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但别悲伤,振作起来
03:27
What if you could find out that, using运用 the DNA脱氧核糖核酸 in museum博物馆 specimens标本,
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如果你发现利用博物馆标本
03:31
fossils化石 maybe up to 200,000 years年份 old
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或是20万年前化石中的DNA
03:34
could be used to bring带来 species种类 back,
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可以让这些物种复活
03:36
what would you do? Where would you start开始?
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你会怎么做呢?你又会从何做起?
03:38
Well, you'd start开始 by finding发现 out if the biotech生物技术 is really there.
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你可能会先确定,生物技术是否达得到要求
03:41
I started开始 with my wife妻子, Ryan瑞安 Phelan费伦,
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我则是从我太太莱恩·费伦娜开始
03:43
who ran a biotech生物技术 business商业 called DNA脱氧核糖核酸 Direct直接,
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她经营一家叫DNA direct的生技公司
03:46
and through通过 her, one of her colleagues同事, George乔治 Church教会,
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透过她,我认识了她的同事乔治.邱奇
03:50
one of the leading领导 genetic遗传 engineers工程师
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他也是位着迷于旅鸽的
03:53
who turned转身 out to be also obsessed痴迷 with passenger乘客 pigeons鸽子
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顶尖基因工程师
03:56
and a lot of confidence置信度
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他对他所使用的方法深具信心
03:58
that methodologies方法 he was working加工 on
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他对他所使用的方法深居信心
04:00
might威力 actually其实 do the deed契据.
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并认为他可以让物种复活
04:02
So he and Ryan瑞安 organized有组织的 and hosted托管 a meeting会议
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所以他和莱恩策划并主持了一个会议
04:05
at the Wyss威斯 Institute研究所 in Harvard哈佛 bringing使 together一起
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在哈佛的维斯学院召集了一批
04:08
specialists专家 on passenger乘客 pigeons鸽子, conservation保护 ornithologists鸟类学家, bioethicists生物伦理学家,
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旅鸽专家、鸟类保育学家、生物伦理学家
04:12
and fortunately幸好 passenger乘客 pigeon鸽子 DNA脱氧核糖核酸 had already已经 been sequenced测序
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而且很幸运的是旅鸽的DNA已经被
04:16
by a molecular分子 biologist生物学家 named命名 Beth贝丝 Shapiro夏皮罗.
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一名叫做贝丝.夏皮罗的分子生物学家完成定序
04:20
All she needed需要 from those specimens标本 at the Smithsonian史密森
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而她只用了保存在史密森纳研究院
04:22
was a little bit of toe脚趾 pad tissue组织,
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标本中的一小块脚部组织
04:25
because down in there is what is called ancient DNA脱氧核糖核酸.
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因为里面含有原始DNA
04:28
It's DNA脱氧核糖核酸 which哪一个 is pretty漂亮 badly fragmented支离破碎,
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DNA已经碎裂成片段
04:31
but with good techniques技术 now, you can basically基本上 reassemble重组 the whole整个 genome基因组.
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利用现在的技术,你可以重组完整的基因序列
04:36
Then the question is, can you reassemble重组,
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问题在于你能不能利用基因体
04:39
with that genome基因组, the whole整个 bird?
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重新“组合”出健全的鸟?
04:41
George乔治 Church教会 thinks you can.
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乔治·邱奇认为这可以达到
04:44
So in his book, "RegenesisRegenesis," which哪一个 I recommend推荐,
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在他写的、也是我强力推荐的《重生》中
04:47
he has a chapter章节 on the science科学 of bringing使 back extinct绝种 species种类,
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有一章节解释了复活灭绝物种的技术
04:50
and he has a machine called
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这个仪器被他称为:
04:52
the Multiplex多工 Automated自动化 Genome基因组 Engineering工程 machine.
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多样化自动基因体建构机
04:55
It's kind of like an evolution演化 machine.
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这项技术和演化的机制类似
04:57
You try combinations组合 of genes基因 that you write
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你将不同组合的基因送入细胞
05:00
at the cell细胞 level水平 and then in organs器官 on a chip芯片,
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从细胞层级到组织层级
05:03
and the ones那些 that win赢得, that you can then put
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再把成功存活下来的组织
05:05
into a living活的 organism生物. It'll它会 work.
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送入代理孕母体内,它就会成功
05:07
The precision精确 of this, one of George's乔治的 famous著名 unreadable不可读 slides幻灯片,
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从乔治难以辨识的记录中
05:11
nevertheless虽然 points out that there's a level水平 of precision精确 here
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我们可以知道这项技术的精确度
05:15
right down to the individual个人 base基础 pair.
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达到碱基对的层级
05:18
The passenger乘客 pigeon鸽子 has 1.3 billion十亿 base基础 pairs in its genome基因组.
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后鸽基因体包含13亿对碱基
05:22
So what you're getting得到 is the capability能力 now
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所以你现在能做的是
05:25
of replacing更换 one gene基因 with another另一个 variation变异 of that gene基因.
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把一个基因用它的对偶基因取代
05:28
It's called an allele等位基因.
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(译注:这是用来解决原始基因序列上破裂、缺失的问题)
05:30
Well that's what happens发生 in normal正常 hybridization杂交 anyway无论如何.
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这在正常的精卵结合过程中也会发生
05:33
So this is a form形成 of synthetic合成的 hybridization杂交 of the genome基因组
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所以,我们可用和灭绝物种
05:36
of an extinct绝种 species种类
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最接近的物种
05:38
with the genome基因组 of its closest最近的 living活的 relative相对的.
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组合并修复灭绝物种的基因体
05:42
Now along沿 the way, George乔治 points out that
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在此过程中,乔治指出
05:45
his technology技术, the technology技术 of synthetic合成的 biology生物学,
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他所使用的合成生物学技术
05:48
is currently目前 accelerating加速 at four times the rate of Moore's摩尔定律 Law.
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现在成长速度是莫尔定律的四倍
05:52
It's been doing that since以来 2005, and it's likely容易 to continue继续.
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这从2005开始,也很有可能一直延续下去
05:56
Okay, the closest最近的 living活的 relative相对的 of the passenger乘客 pigeon鸽子
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最接近旅鸽的存活物种是带尾鸽
05:59
is the band-tailed带尾 pigeon鸽子. They're abundant丰富. There's some around here.
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牠们数量庞大,在这附近也有
06:02
Genetically基因, the band-tailed带尾 pigeon鸽子 already已经 is
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从基因层面来说,带尾鸽似乎是活着的旅鸽
06:07
mostly大多 living活的 passenger乘客 pigeon鸽子.
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牠们的基因体中只有一些带尾鸽特有的序列
06:09
There's just some bits that are band-tailed带尾 pigeon鸽子.
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牠们的基因体中只有一些带尾鸽特有的序列
06:11
If you replace更换 those bits with passenger乘客 pigeon鸽子 bits,
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如果你将这些序列以旅鸽特有的序列取代
06:14
you've got the extinct绝种 bird back, cooing咕咕 at you.
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你就有一只已经灭绝的旅鸽对你咕咕叫
06:18
Now, there's work to do.
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现在需要着手进行的是:
06:20
You have to figure数字 out exactly究竟 what genes基因 matter.
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你必须分辨出那些基因是重要的
06:23
So there's genes基因 for the short tail尾巴 in the band-tailed带尾 pigeon鸽子,
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像是带尾鸽拥有短尾的基因
06:26
genes基因 for the long tail尾巴 in the passenger乘客 pigeon鸽子,
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而旅鸽则是表现长尾的基因
06:28
and so on with the red eye, peach-colored桃红色 breast乳房, flocking植绒, and so on.
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还有红颜、桃红色的胸部和群集行为等基因
06:32
Add them all up and the result结果 won't惯于 be perfect完善.
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将这些都加在一起,结果不会是完美的
06:35
But it should be be perfect完善 enough足够,
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但应该就近乎完美了
06:37
because nature性质 doesn't do perfect完善 either.
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自然界中也没有完美的作品
06:39
So this meeting会议 in Boston波士顿 led to three things.
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所以,在波士顿的会议中决定了三件事
06:43
First off, Ryan瑞安 and I decided决定 to create创建 a nonprofit非营利性
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首先,我和莱恩创立了个非盈利组织
06:47
called Revive复活 and Restore恢复 that would push de-extinction去灭绝 generally通常
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这个名为“复活与保存”的组织致力于
06:51
and try to have it go in a responsible主管 way,
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以负责任的方式推动“反灭绝”
06:54
and we would push ahead with the passenger乘客 pigeon鸽子.
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而我们将先从旅鸽做起
06:57
Another另一个 direct直接 result结果 was a young年轻 grad毕业 student学生 named命名 Ben Novak诺瓦克,
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另一项结果是本·诺瓦克,一位年轻研究生
07:01
who had been obsessed痴迷 with passenger乘客 pigeons鸽子 since以来 he was 14
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他从14岁起就为旅鸽所深深着迷
07:04
and had also learned学到了 how to work with ancient DNA脱氧核糖核酸,
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而且在学会如何操作原始DNA后
07:07
himself他自己 sequenced测序 the passenger乘客 pigeon鸽子,
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他利用家人和朋友的帮助
07:11
using运用 money from his family家庭 and friends朋友.
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完成了旅鸽基因体定序
07:13
We hired雇用 him full-time全职.
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我们雇佣了他
07:16
Now, this photograph照片 I took of him last year at the Smithsonian史密森,
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这是一张在去年在史密森纳我帮他照的照片
07:19
he's looking down at Martha玛莎,
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照片中他低头看着玛莎
07:21
the last passenger乘客 pigeon鸽子 alive.
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世界上最后一只旅鸽
07:24
So if he's successful成功, she won't惯于 be the last.
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如果他成功的话,它就不会是最后一只
07:27
The third第三 result结果 of the Boston波士顿 meeting会议 was the realization实现
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波士顿会议的第三项结果是
07:30
that there are scientists科学家们 all over the world世界
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让我们了解到世界上有许多科学家
07:32
working加工 on various各个 forms形式 of de-extinction去灭绝,
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在进行不同形式的反灭绝
07:34
but they'd他们会 never met会见 each other.
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但他们素未谋面
07:35
And National国民 Geographic地理 got interested有兴趣
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而国家地理频道对此很感兴趣
07:37
because National国民 Geographic地理 has the theory理论 that
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因为他们有个想法
07:40
the last century世纪, discovery发现 was basically基本上 finding发现 things,
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就是上世纪的发现是为了寻找未知
07:43
and in this century世纪, discovery发现 is basically基本上 making制造 things.
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而这个世纪是在创造发明
07:47
De-extinction德灭绝 falls下降 in that category类别.
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而灭绝符合此条件
07:49
So they hosted托管 and funded资助 this meeting会议. And 35 scientists科学家们,
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所以他们资助并主办了这场会议
07:53
they were conservation保护 biologists生物学家 and molecular分子 biologists生物学家,
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让35位保育生物学家和分子生物学家
07:56
basically基本上 meeting会议 to see if they had work to do together一起.
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见面并讨论合作机会
08:00
Some of these conservation保护 biologists生物学家 are pretty漂亮 radical激进.
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其中一些保育生物学家非常激进
08:02
There's three of them who are not just re-creating重新创建 ancient species种类,
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其中三人不只要让古生物复活
08:06
they're recreating再创造 extinct绝种 ecosystems生态系统
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他们更希望在北西伯利亚、荷兰和夏威夷
08:09
in northern北方 Siberia西伯利亚, in the Netherlands荷兰, and in Hawaii夏威夷.
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恢复已经消失的生态系统
08:13
Henri亨利, from the Netherlands荷兰,
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来自荷兰的亨利
08:15
with a Dutch荷兰人 last name名称 I won't惯于 try to pronounce发音,
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嗯,我不大会说他的荷兰姓氏
08:18
is working加工 on the aurochs野牛.
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在做欧洲野牛
08:20
The aurochs野牛 is the ancestor祖先 of all domestic国内 cattle黄牛,
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欧洲野牛是所有被驯养牛种的祖先
08:24
and so basically基本上 its genome基因组 is alive, it's just unevenly不均匀 distributed分散式.
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所以牠的基因体还存在,只是不平均的散布在不同品种里
08:30
So what they're doing is working加工 with seven breeds品种
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所以他们利用七个原始、强韧
08:32
of primitive原始, hardy-looking耐寒的前瞻性 cattle黄牛 like that MaremmanaMaremmana酒店 primitivo普里米蒂沃 on the top最佳 there
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和上图原牛相似的品种
08:37
to rebuild重建, over time, with selective可选择的 back-breeding回养殖,
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利用筛选性的繁殖
08:40
the aurochs野牛.
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希望可以让欧洲野牛重现
08:43
Now, re-wilding重野化 is moving移动 faster更快 in Korea韩国
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现在野放在韩国推展的
08:46
than it is in America美国,
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比美国更为迅速
08:47
and so the plan计划 is, with these re-wilded再wilded areas all over Europe欧洲,
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所以我们计划将野牛引进欧洲的野放区
08:51
they will introduce介绍 the aurochs野牛 to do its old job工作,
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让他们扮演原有的生态功能
08:54
its old ecological生态 role角色,
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他们原本在生态系统中扮演的角色
08:56
of clearing空地 the somewhat有些 barren荒芜, closed-canopy闭篷 forest森林
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让原本茂密森林下的贫瘠土壤
08:59
so that it has these biodiverse生物多样性 meadows草甸 in it.
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重现多样化的草原植被
09:03
Another另一个 amazing惊人 story故事
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另一个令人惊叹的故事
09:05
came来了 from Alberto阿尔贝托 Fern蕨类ández-Ariasndez阿里亚斯.
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是来自阿贝图.费尔南斯.阿里
09:08
Alberto阿尔贝托 worked工作 with the bucardoBucardo这 in Spain西班牙.
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阿贝图在西班牙研究布卡多山羊
09:12
The last bucardoBucardo这 was a female named命名 Celia西莉亚
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最后一只是名叫西丽亚的母羊
09:15
who was still alive, but then they captured捕获 her,
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当研究员捕捉它时它还健在
09:19
they got a little bit of tissue组织 from her ear,
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当时他们从他耳朵取得一小块组织
09:22
they cryopreserved冻存 it in liquid液体 nitrogen,
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并冷冻保存于液态氮中后
09:25
released发布 her back into the wild野生,
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将他野放
09:27
but a few少数 months个月 later后来, she was found发现 dead under a fallen堕落 tree.
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但数个月后发现他被树木压死
09:30
They took the DNA脱氧核糖核酸 from that ear,
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他们利用他耳朵中的DNA
09:33
they planted种植的 it as a cloned克隆 egg in a goat山羊,
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恢复成受精卵的形式并植入山羊
09:36
the pregnancy怀孕 came来了 to term术语,
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当孕期结束
09:38
and a live生活 baby宝宝 bucardoBucardo这 was born天生.
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活生生的布卡多山羊就出生了
09:41
It was the first de-extinction去灭绝 in history历史.
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这是历史上第一个反灭绝的实例
09:44
(Applause掌声)
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(掌声)
09:47
It was short-lived短命.
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但牠活的不久
09:48
Sometimes有时 interspecies异种 clones克隆 have respiration呼吸 problems问题.
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有时跨种的复制会造成生物呼吸系统的问题
09:52
This one had a malformed异常 lung and died死亡 after 10 minutes分钟,
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这只肺脏发育不全的羊只存活了10 分钟
09:55
but Alberto阿尔贝托 was confident信心 that
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但阿贝图对深具信心
09:58
cloning克隆 has moved移动 along沿 well since以来 then,
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因为动物复制技术已有长足进步
10:00
and this will move移动 ahead, and eventually终于
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未来终究会更加发达
10:02
there will be a population人口 of bucardosbucardos
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他相信未来会有成群的布卡多山羊
10:04
back in the mountains in northern北方 Spain西班牙.
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重返西班牙北部的山区
10:07
Cryopreservation冷冻保存 pioneer先锋 of great depth深度 is Oliver奥利弗 Ryder莱德.
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冷冻保存的先驱奥利弗·雷德
10:11
At the San Diego迭戈 zoo动物园, his frozen冻结的 zoo动物园
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在圣地亚哥动物园中
10:13
has collected the tissues组织 from over 1,000 species种类
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他的冰冻园区在过去35年内
10:17
over the last 35 years年份.
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搜集了超过1千种物种的组织
10:20
Now, when it's frozen冻结的 that deep,
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当冰封在低温——
10:22
minus减去 196 degrees Celsius摄氏,
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-196摄氏度
10:25
the cells细胞 are intact完整 and the DNA脱氧核糖核酸 is intact完整.
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细胞和其中的DNA都可以完整保存
10:28
They're basically基本上 viable可行 cells细胞,
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它们基本上都是能培养的细胞
10:30
so someone有人 like Bob短发 Lanza兰扎 at Advanced高级 Cell细胞 Technology技术
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先进细胞科技公司的鲍勃·兰扎
10:33
took some of that tissue组织 from an endangered濒危 animal动物
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从濒临绝种的爪哇野牛的冷冻组织中
10:37
called the Javan爪哇 banteng雄牛, put it in a cow,
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取了一些植入母乳牛
10:39
the cow went to term术语, and what was born天生
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当母牛孕期届满
10:42
was a live生活, healthy健康 baby宝宝 Javan爪哇 banteng雄牛,
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一只健康的爪哇野牛宝宝就诞生了
10:47
who thrived蓬勃发展 and is still alive.
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牠仍健在,也在持续成长中
10:50
The most exciting扣人心弦 thing for Bob短发 Lanza兰扎
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最让鲍勃兴奋的是
10:53
is the ability能力 now to take any kind of cell细胞
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现在可以将任何细胞诱导成全能干细胞
10:56
with induced诱发 pluripotent多能 stem cells细胞
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并将其分化成如精子、卵子
10:58
and turn it into germ病菌 cells细胞, like sperm精子 and eggs.
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这类生殖细胞的技术
11:02
So now we go to Mike麦克风 McGrew麦克格鲁
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现在我们来介绍麦克·麦格罗
11:05
who is a scientist科学家 at Roslin罗斯林 Institute研究所 in Scotland苏格兰,
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他是一位在苏格兰罗斯林研究所的科学家
11:08
and Mike's迈克的 doing miracles奇迹 with birds鸟类.
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麦克在鸟类上展现奇迹
11:10
So he'll地狱 take, say, falcon skin皮肤 cells细胞, fibroblast成纤维细胞,
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他会拿猎鹰的皮肤细胞,例如纤维母细胞
11:14
turn it into induced诱发 pluripotent多能 stem cells细胞.
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让它恢复成全能干细胞
11:17
Since以来 it's so pluripotent多能, it can become成为 germ病菌 plasm血浆.
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因为它具有全能性,所以也可以分化成种质
11:20
He then has a way to put the germ病菌 plasm血浆
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然后他有种方法可以将种质
11:22
into the embryo of a chicken egg
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送入鸡蛋的胚胎中
11:26
so that that chicken will have, basically基本上,
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所以这只鸡将会长出
11:29
the gonads性腺 of a falcon.
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猎鹰的生殖腺
11:31
You get a male and a female each of those,
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当你把他们凑成对后
11:33
and out of them comes falcons猎鹰.
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就可以生出猎鹰了
11:36
(Laughter笑声)
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(笑声)
11:38
Real真实 falcons猎鹰 out of slightly doctored篡改 chickens.
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从改造的鸡生出猎鹰
11:43
Ben Novak诺瓦克 was the youngest最年轻的 scientist科学家 at the meeting会议.
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本·诺瓦克是会议中最年轻的科学家
11:45
He showed显示 how all of this can be put together一起.
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他展示了如何让这些技术衔接在一起
11:48
The sequence序列 of events事件: he'll地狱 put together一起 the genomes基因组
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流程如下:他会先利用带尾鸽
11:50
of the band-tailed带尾 pigeon鸽子 and the passenger乘客 pigeon鸽子,
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和旅鸽的基因体放在一起
11:53
he'll地狱 take the techniques技术 of George乔治 Church教会
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再利用乔治·邱奇的技术
11:56
and get passenger乘客 pigeon鸽子 DNA脱氧核糖核酸,
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修复旅鸽的DNA
11:58
the techniques技术 of Robert罗伯特 Lanza兰扎 and Michael迈克尔 McGrew麦克格鲁,
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罗伯特·兰扎和麦克·麦格罗的技术
12:01
get that DNA脱氧核糖核酸 into chicken gonads性腺,
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则可以将DNA送入鸡的生殖腺
12:03
and out of the chicken gonads性腺 get passenger乘客 pigeon鸽子 eggs, squabssquabs,
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并生出旅鸽蛋、孵化成雏鸽
12:07
and now you're getting得到 a population人口 of passenger乘客 pigeons鸽子.
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你就可以得到旅鸽族群
12:11
It does raise提高 the question of,
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这可能会有个问题:
12:13
they're not going to have passenger乘客 pigeon鸽子 parents父母
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没有旅鸽亲鸟
12:15
to teach them how to be a passenger乘客 pigeon鸽子.
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如何教导乳鸽成为一只真正的旅鸽
12:17
So what do you do about that?
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你会怎么解决这个问题?
12:19
Well birds鸟类 are pretty漂亮 hard-wired硬连线, as it happens发生,
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还好大部分鸟类行为
12:22
so most of that is already已经 in their DNA脱氧核糖核酸,
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都包含在他们的DNA里
12:25
but to supplement补充 it, part部分 of Ben'sBen的 idea理念
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单位了保险起见,他提出一个想法:
12:27
is to use homing归巢 pigeons鸽子
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利用信鸽
12:29
to help train培养 the young年轻 passenger乘客 pigeons鸽子 how to flock
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教导年轻的旅鸽如何结队飞行
12:32
and how to find their way to their old nesting嵌套 grounds理由
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并且找到原本筑巢、
12:35
and feeding馈送 grounds理由.
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育幼的地方
12:38
There were some conservationists保守主义者,
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有一些保育学家
12:40
really famous著名 conservationists保守主义者 like Stanley斯坦利 Temple寺庙,
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包含创立保育生物学的
12:43
who is one of the founders创始人 of conservation保护 biology生物学,
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著名科学家史坦利·邓波
12:45
and Kate凯特 Jones琼斯 from the IUCN世界自然保护联盟, which哪一个 does the Red List名单.
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和IUCN负责编纂红名单的凯特·琼斯
(IUCN:国际自然保护联盟)
12:50
They're excited兴奋 about all this,
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他们对此都非常振奋
12:52
but they're also concerned关心 that it might威力 be competitive竞争的
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但他们也担心这会和保护还存活的濒临灭绝动物
12:54
with the extremely非常 important重要 efforts努力 to protect保护
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但他们也担心这会和保护还存活的濒临灭绝动物
12:58
endangered濒危 species种类 that are still alive,
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这项重要工作竞争资源
13:00
that haven't没有 gone走了 extinct绝种 yet然而.
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这项重要工作竞争资源
13:02
You see, you want to work on protecting保护 the animals动物 out there.
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你必须保护还存活着的动物
13:04
You want to work on getting得到 the market市场 for ivory象牙 in Asia亚洲 down
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为了避免每年2.5万头被猎杀的大象
13:08
so you're not using运用 25,000 elephants大象 a year.
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你必须停止亚洲的象牙交易
13:12
But at the same相同 time, conservation保护 biologists生物学家 are realizing实现
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但同时保育生物学家也发现
13:15
that bad news新闻 bums烧伤 people out.
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坏消息使人丧气
13:18
And so the Red List名单 is really important重要, keep track跟踪 of
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所以即使负责追踪危险和
濒临灭绝动物的红名单很重要
13:20
what's endangered濒危 and critically危重 endangered濒危, and so on.
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所以即使负责追踪危险和
濒临灭绝动物的红名单很重要
13:24
But they're about to create创建 what they call a Green绿色 List名单,
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但是他们也准备编纂绿名单
13:27
and the Green绿色 List名单 will have species种类 that are doing fine, thank you,
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而绿名单会告诉你哪些物种现在过得很好
13:31
species种类 that were endangered濒危, like the bald eagle,
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曾经濒临绝种的白头鹰
13:33
but they're much better off now, thanks谢谢 to everybody's每个人的 good work,
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因为大家的努力,现在他们的状况已经转好
13:37
and protected保护 areas around the world世界
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而各地的保育区
13:39
that are very, very well managed管理.
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也都经营完善
13:41
So basically基本上, they're learning学习 how to build建立 on good news新闻.
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所以他们现在也试着散布好消息
13:45
And they see reviving复兴 extinct绝种 species种类
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而让灭种生物复活
13:48
as the kind of good news新闻 you might威力 be able能够 to build建立 on.
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就是一个你会想得到的好消息
13:51
Here's这里的 a couple一对 related有关 examples例子.
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这里有几个相关的例子
13:54
Captive俘虏 breeding配种 will be a major重大的 part部分 of bringing使 back these species种类.
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人工繁殖培育是复育生物的重要环节
13:58
The California加州 condor秃鹰 was down to 22 birds鸟类 in 1987.
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加州神鹫在 1987 年仅剩 22 只
14:01
Everybody每个人 thought is was finished.
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大家都觉得他们要消失了
14:03
Thanks谢谢 to captive俘虏 breeding配种 at the San Diego迭戈 Zoo动物园,
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因为圣地亚哥动物园的人工繁殖培育
14:06
there's 405 of them now, 226 are out in the wild野生.
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现在已有405只,其中226只已经野放
14:10
That technology技术 will be used on de-extincted去extincted animals动物.
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这项技术会被用在反灭绝复育的物种
14:14
Another另一个 success成功 story故事 is the mountain gorilla大猩猩 in Central中央 Africa非洲.
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另外一个成功的故事是中非的巨猩
14:17
In 1981, Dian Fossey弗西 was sure they were going extinct绝种.
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在1981年黛安·弗里确信他们要灭绝了
14:21
There were just 254 left.
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他们仅剩254只
14:23
Now there are 880. They're increasing增加 in population人口
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现在已经有880只
14:26
by three percent百分 a year.
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并且逐年上升3%
14:28
The secret秘密 is, they have an eco-tourism生态旅游 program程序,
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秘诀就在于他们推动生态旅游计划
14:32
which哪一个 is absolutely绝对 brilliant辉煌.
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这招很聪明
14:33
So this photograph照片 was taken采取 last month by Ryan瑞安
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这张照片是上个月莱恩
14:36
with an iPhone苹果手机.
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用iphone拍的
14:39
That's how comfortable自在 these wild野生 gorillas大猩猩 are with visitors游客.
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野生巨猩在游客前面显得多么自在
14:43
Another另一个 interesting有趣 project项目, though虽然 it's going to need some help,
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另外一个需要我们帮助的计划
14:47
is the northern北方 white白色 rhinoceros犀牛.
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是关于北白犀牛
14:49
There's no breeding配种 pairs left.
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他们已经没有能生育的配对了
14:51
But this is the kind of thing that
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但是这种动物 多样化的DNA
14:53
a wide variety品种 of DNA脱氧核糖核酸 for this animal动物 is available可得到 in the frozen冻结的 zoo动物园.
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保存于冷冻园区
14:57
A bit of cloning克隆, you can get them back.
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只要做个复制,你就能把他们救回来
15:00
So where do we go from here?
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所以我们未来的方向是什么?
15:02
These have been private私人的 meetings会议 so far.
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过去一直都是私人集会
15:04
I think it's time for the subject学科 to go public上市.
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我觉得应该让大众了解到这个议题
15:06
What do people think about it?
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大家会怎么想呢?
15:08
You know, do you want extinct绝种 species种类 back?
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你们会想要让就回灭绝动物吗?
15:10
Do you want extinct绝种 species种类 back?
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你们会吗?
15:13
(Applause掌声)
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(掌声)
15:18
Tinker修补匠 Bell is going to come fluttering飘飘 down.
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彼得潘的小叮当已经翩翩降临
15:20
It is a Tinker修补匠 Bell moment时刻,
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现在正是弥补过去的时刻
15:22
because what are people excited兴奋 about with this?
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大家为何感到兴奋?
15:24
What are they concerned关心 about?
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他们关心什么?
15:26
We're also going to push ahead with the passenger乘客 pigeon鸽子.
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我们会先从旅鸽着手
15:29
So Ben Novak诺瓦克, even as we speak说话, is joining加盟 the group
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就在此时,本·诺瓦克
15:32
that Beth贝丝 Shapiro夏皮罗 has at UCUC Santa圣诞老人 Cruz克鲁兹.
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已和加大圣克鲁分校的贝丝·夏皮罗合作
15:36
They're going to work on the genomes基因组
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他们正在进行
15:37
of the passenger乘客 pigeon鸽子 and the band-tailed带尾 pigeon鸽子.
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旅鸽和带尾鸽基因体的研究
15:39
As that data数据 matures成熟, they'll他们会 send发送 it to George乔治 Church教会,
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当研究结果成熟时,他们会交给乔治·邱奇
15:43
who will work his magic魔法, get passenger乘客 pigeon鸽子 DNA脱氧核糖核酸 out of that.
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让他展现魔法还原旅鸽DNA
15:47
We'll get help from Bob短发 Lanza兰扎 and Mike麦克风 McGrew麦克格鲁
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再藉由鲍勃·兰扎和麦克·麦格罗的帮助
15:50
to get that into germ病菌 plasm血浆 that can go into chickens
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将种质放进机体内
15:53
that can produce生产 passenger乘客 pigeon鸽子 squabssquabs
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让他们生下小旅鸽
15:56
that can be raised上调 by band-tailed带尾 pigeon鸽子 parents父母,
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再让带尾鸽将他们抚养长大
15:58
and then from then on, it's passenger乘客 pigeons鸽子 all the way,
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继续这样下去,旅鸽就可以自行繁衍
16:00
maybe for the next下一个 six million百万 years年份.
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或许他们可在天空翱翔下个60万年
16:03
You can do the same相同 thing, as the costs成本 come down,
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当成本降低时
16:06
for the Carolina卡罗来纳州 parakeet多嘴的人, for the great auk海雀,
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可以对卡罗莱纳长尾鹦鹉、大海确、
16:09
for the heath健康 hen母鸡, for the ivory-billed象牙喙 woodpecker啄木鸟,
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北美松鸡、象牙喙啄木鸟、
16:12
for the Eskimo爱斯基摩 curlew麻鹬, for the Caribbean加勒比 monk seal密封,
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爱斯基摩杓鹬、加勒比僧海豹、
16:14
for the woolly长毛 mammoth长毛象.
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和长毛象进行相同的复活程序
16:17
Because the fact事实 is, humans人类 have made制作 a huge巨大 hole
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事实如此:在过去的一万年
16:19
in nature性质 in the last 10,000 years年份.
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人类让自然遭受了巨大的创伤
16:22
We have the ability能力 now,
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而今我们有能力
16:24
and maybe the moral道德 obligation义务, to repair修理 some of the damage损伤.
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或许也有义务去修复这些损害
16:29
Most of that we'll do by expanding扩大 and protecting保护 wildlands荒地,
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我们大部分通过扩展保育原生地
16:34
by expanding扩大 and protecting保护
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以及扩大并保护
16:35
the populations人群 of endangered濒危 species种类.
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濒临绝种的物种族群 来达成任务
16:40
But some species种类
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但对某些物种而言
16:42
that we killed杀害 off totally完全
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我们已经将他们赶尽杀绝了
16:47
we could consider考虑 bringing使 back
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我们可以试着让他们复活
16:51
to a world世界 that misses错过 them.
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回到想念他们的世界
16:54
Thank you.
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谢谢大家
16:56
(Applause掌声)
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(掌声)
17:07
Chris克里斯 Anderson安德森: Thank you.
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查理斯·安德森:谢谢你
17:09
I've got a question.
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我有个问题
17:11
So, this is an emotional情绪化 topic话题. Some people stand.
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这是个感性的话题。有人支持
17:16
I suspect疑似 there are some people out there sitting坐在,
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我相信也有些人
17:19
kind of asking tormented折磨 questions问题, almost几乎, about,
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会有个苦恼的问题:
17:22
well, wait, wait, wait, wait, wait, wait a minute分钟,
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等等等一下,
17:23
there's something wrong错误 with mankind人类
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人类不应该这样
17:27
interfering干扰 in nature性质 in this way.
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干预自然
17:30
There's going to be unintended意外 consequences后果.
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这可能会有预期外的后果
17:33
You're going to uncork泄漏 some sort分类 of Pandora's潘多拉 box
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你将打开潘多拉的盒子
17:36
of who-knows-what谁也不知道的什么. Do they have a point?
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谁知道里面装了什么。他们这样说有道理吗?
17:40
Stewart斯图尔特 Brand: Well, the earlier point is
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史都华·布兰德:嗯,首先
17:42
we interfered干扰 in a big way by making制造 these animals动物 go extinct绝种,
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是我们人类先干预自然,造成物种灭绝
17:45
and many许多 of them were keystone拱心石 species种类,
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许多都是关键物种
17:48
and we changed the whole整个 ecosystem生态系统 they were in
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让他们灭绝的同时
17:50
by letting出租 them go.
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我们也对生态系统造成冲击
17:52
Now, there's the shifting baseline底线 problem问题, which哪一个 is,
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最根本的问题是:
17:55
so when these things come back,
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当我们把它们复活时
17:56
they might威力 replace更换 some birds鸟类 that are there
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他们可能会取代现在在那里的鸟类
17:59
that people really know and love.
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而这些可能也是人类认识并喜爱的物种
18:01
I think that's, you know, part部分 of how it'll它会 work.
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我想这个能给你们一个它发展方向的概念
18:04
This is a long, slow process处理 --
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这是一个漫长且缓慢的过程
18:07
One of the things I like about it, it's multi-generation多代.
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让我兴奋的是,这需要好几世代的努力
18:09
We will get woolly长毛 mammoths猛犸象 back.
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我们可以将长毛象复活
18:11
CACA: Well it feels感觉 like both the conversation会话
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查:我相信这场谈话
18:13
and the potential潜在 here are pretty漂亮 thrilling惊险.
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和其潜力都很令人振奋
18:15
Thank you so much for presenting呈现. SBSB: Thank you.
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感谢你的演说 史:谢谢
18:17
CACA: Thank you. (Applause掌声)
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查:谢谢你们(掌声)
Translated by Tracy Zheng
Reviewed by Emma Chiang

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ABOUT THE SPEAKER
Stewart Brand - Environmentalist, futurist
Since the counterculture '60s, Stewart Brand has been creating our internet-worked world. Now, with biotech accelerating four times faster than digital technology, Stewart Brand has a bold new plan ...

Why you should listen

With biotech accelerating four times faster than digital technology, the revival of extinct species is becoming possible. Stewart Brand plans to not only bring species back but restore them to the wild.

Brand is already a legend in the tech industry for things he’s created: the Whole Earth Catalog, The WELL, the Global Business Network, the Long Now Foundation, and the notion that “information wants to be free.” Now Brand, a lifelong environmentalist, wants to re-create -- or “de-extinct” -- a few animals that’ve disappeared from the planet.

Granted, resurrecting the woolly mammoth using ancient DNA may sound like mad science. But Brand’s Revive and Restore project has an entirely rational goal: to learn what causes extinctions so we can protect currently endangered species, preserve genetic and biological diversity, repair depleted ecosystems, and essentially “undo harm that humans have caused in the past.”

More profile about the speaker
Stewart Brand | Speaker | TED.com