ABOUT THE SPEAKER
Simona Francese - Analytical chemist
Simona Francese is a chemist by training who is passionate about forensics.

Why you should listen

Simona Francese is a Professor of Forensic and Bioanalytical Mass Spectrometry at Sheffield Hallam University in the UK. As she writes: "I have been fascinated by forensics since I was 17, and I was determined to pursue an educational route that eventually would enable me to contribute to secure societies. As always in life, nothing is straightforward. I enrolled in the chemistry course because it was the closest degree at the time that could lead me to where I wanted to be. I ended up doing a PhD and post-doctorate fellowships working with viruses and diseases. But I was always focused on my ultimate objective, and throughout I developed a strong expertise in mass spectrometry, which is an extremely versatile analytical technique. This was crucial.

"When I obtained my first lectureship, I had the freedom to build my own research, and I used mass spectrometry imaging to develop ways to profile individuals from their fingermarks, thus helping police with their investigations. What has the suspect been handling? What is their lifestyle? What did he do prior to or while committing the crime? These are some of the questions that the developed technology can answer, and we are working on providing additional information -- for example, on the pathological or pharmacological state of the individual, just from looking at their fingermark! A fantastic achievement for me, but the best accomplishment was keeping the focus for 14 years and remaining determined to finally be able to do what I have always been so passionate about."

More profile about the speaker
Simona Francese | Speaker | TED.com
TED2018

Simona Francese: Your fingerprints reveal more than you think

席夢娜法蘭西絲: 指紋揭露的資訊比你想像的還多

Filmed:
2,372,231 views

我們的指紋讓我們獨一無二,也貯藏著許多資訊。這些資訊隱藏在分子背後,能揭露出我們的行為、生活方式和日常慣行。在這場很吸引人的演說中,化學家席夢娜法蘭西絲展示她如何用質譜儀來研究這些顯微蹤跡。質譜儀技術能詳細分析指紋,這是以前做不到的。她也展示這先進的法庭科學如何能協助警方抓到罪犯。
- Analytical chemist
Simona Francese is a chemist by training who is passionate about forensics. Full bio

Double-click the English transcript below to play the video.

00:12
Do you ever stop and think,
during a romantic浪漫 dinner晚餐,
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你可曾在吃一頓浪漫
晚餐時,停下來想:
「我剛在酒杯上留下
滿滿的指紋了。」
00:17
"I've just left my fingerprints指紋
all over my wine紅酒 glass玻璃."
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(笑聲)
00:20
(Laughter笑聲)
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或者,你可曾在拜訪朋友時擔心過
00:21
Or do you ever worry擔心,
when you visit訪問 a friend朋友,
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在你所碰觸到的每個表面上
留下你的一小部分?
00:24
about leaving離開 a little piece of you behind背後
on every一切 surface表面 that you touch觸摸?
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00:30
And even this evening晚間,
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甚至今晚,
你是否有注意到在坐下來的
過程中不要碰觸任何東西?
00:31
have you paid支付 any attention注意
to sit without touching接觸 anything?
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00:36
Well, you're not alone單獨.
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嗯,你並不孤單。
謝天謝地,罪犯低估了指紋的力量。
00:37
Thankfully感激地, criminals罪犯 underestimate低估
the power功率 of fingerprints指紋, too.
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00:42
And I'm not just talking about
the twisted扭曲 parting離別 of lines
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我在談的不只是讓指紋獨一無二的
00:46
that make our fingerprint指紋 unique獨特.
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那些分開的彎曲線條。
我談的是隱藏在
這通常看不見的小東西背後的
00:49
I'm talking about
an entire整個 world世界 of information信息
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00:53
hiding in a small, often經常 invisible無形 thing.
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一整個資訊世界。
00:57
In fact事實, fingerprints指紋
are made製作 up of molecules分子
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事實上,指紋是由分子所組成的,
共有三類分子:
01:00
that belong屬於 to three classes:
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汗分子,這是我們都會產生的,
只是量有所不同……
01:02
sweat molecules分子 that we all produce生產
in very different不同 amounts ...
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我們帶入身體當中,
接著透過汗水排出的分子,
01:07
molecules分子 that we introduce介紹 into our body身體
and then we sweat out
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以及我們的指尖沾到的分子,
01:11
and molecules分子 that we may可能 contaminate污染
our fingertips指尖 with
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可能是在我們碰觸到
血液、染料、油脂這類物質,
01:15
when we come across橫過 substances物質
like blood血液, paint塗料, grease潤滑脂,
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或看不見的物質時沾到的。
01:18
but also invisible無形 substances物質.
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01:21
And molecules分子 are
the storytellers講故事的人 of who we are
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分子會說故事,說出我們是誰,
及我們過去做了些什麼。
01:26
and what we've我們已經 been up to.
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01:28
We just need to have
the right technology技術 to make them talk.
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我們只需要有對的技術,
就能讓分子說話。
01:34
So let me take you on a journey旅程
of unthinkable不可思議的 capabilities功能.
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所以,讓我帶大家踏上一段旅程,
見識一下無法想像的能力。
01:42
Katie凱蒂 has been raped強姦
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凱蒂被強暴了,
01:45
and her lifeless死氣沉沉 body身體 has been found發現
in the woods樹木 three days later後來,
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她失蹤的三天後,
她的屍體在樹林裡被發現,
已無生命跡象。
01:50
after her disappearance消失.
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01:52
The police警察 is targeting針對 three suspects犯罪嫌疑人,
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警方鎖定三名嫌犯,
這三人是他們在追查了當天
在那個區域被人看見的
01:55
having narrowed收窄 down
the search搜索 from over 20 men男人
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01:59
who had been seen看到
in that area on the same相同 day.
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二十多名男子之後篩選出來的。
02:02
The only piece of evidence證據
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唯一的一項證據
就是兩個非常模糊
且重疊在一起的指紋,
02:04
is two very faint,
overlapping重疊 fingerprints指紋
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這兩個指紋位在纏繞在
凱蒂脖子上的膠帶上。
02:09
on the tape膠帶 that was found發現
wrapped包裹 around Katie's凱蒂的 neck頸部.
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02:13
Often經常, faint and overlapping重疊 fingerprints指紋
cannot不能 help the police警察
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通常,模糊又重疊的指紋
無法協助警方
辨識出指紋主人的身分。
02:18
to make an identification鑑定.
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直到最近之前,這都是死路一條,
02:20
And until直到 recently最近,
this might威力 have been the end結束 of the road,
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02:25
but this is where
we can make the difference區別.
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但這正是我們可以
造成不同的地方。
02:29
The tape膠帶 is sent發送 to our labs實驗室,
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膠帶被送到我們的實驗室,
他們要求我們使用先進技術
02:31
where we're asked to use
our cutting-edge前沿 technology技術
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來協助調查這個案件。
02:34
to help with the investigation調查.
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02:38
And here, we use an existing現有 form形成
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我們使用了質譜成像技術的
02:40
of mass spectrometry imaging成像 technology技術
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一種既有形式,
這種形式是我們進一步發展、
02:45
that we have further進一步 developed發達 and adapted適應
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02:47
specifically特別 for the molecular分子 and imaging成像
analysis分析 of fingerprints指紋.
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並特別針對指紋的分子
和成像分析而改造的形式。
02:53
In essence本質, we fire
a UVUV laser激光 at the print打印,
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本質上,我們對指紋
發射紫外線雷射,
我們會造成指紋分子
產生解吸附作用,
02:57
and we cause原因 the desorption解 吸
of the molecules分子 from the print打印,
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就能夠被質譜儀捕捉。
03:01
ready準備 to be captured捕獲
by the mass spectrometer光譜儀.
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03:05
Mass spectrometry measures措施
the weight重量 of the molecules分子 --
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質譜儀能測量分子的重量——
我們稱之為質量——
03:09
or as we say, the mass --
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各位看到的那些數字,
代表的就是質量。
03:11
and those numbers數字 that you see there,
they indicate表明 that mass.
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但,更重要的,
03:15
But more crucially關鍵,
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它們也能指出那些分子是什麼——
03:17
they indicate表明 who those molecules分子 are --
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我是否有看到撲熱息痛(藥名),
03:22
whether是否 I'm seeing眼看 paracetamol撲 熱 息 痛
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或是在法庭上來說,
更不好的東西。
03:24
or something more sinister險惡,
forensically法醫 speaking請講.
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03:28
We applied應用的 this technology技術
to the evidence證據 that we have
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我們把這項技術用在
我們擁有的證據上,
我們發現上面有保險套潤滑劑。
03:31
and we found發現 the presence存在
of condom避孕套 lubricants潤滑油.
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03:36
In fact事實, we've我們已經 developed發達 protocols協議
that enable啟用 us to even suggest建議
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事實上,我們延伸的實驗報告,
讓我們甚至可以指出
使用的保險套是哪個品牌的。
03:40
what brand of condom避孕套 might威力 have been used.
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03:45
So we pass通過 this information信息 to the police警察,
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我們把這項資訊交給警方,
這期間,警方取得了搜索令,
03:47
who, meanwhile與此同時,
have obtained獲得 a search搜索 warrant保證
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在達爾頓的房宅中找到了
同樣品牌的保險套。
03:50
and they found發現 the same相同 brand
of condom避孕套 in Dalton's道爾頓的 premises房地.
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03:57
And with Dalton道爾頓 and Thomson湯姆森
also having records記錄 for sexual有性 assaults襲擊,
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達爾頓和湯姆森都有性侵的前科,
於是查普曼是嫌犯的可能性
就變得比較小了。
04:02
then it is Chapman查普曼 that may可能 become成為
the less likely容易 suspect疑似.
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04:08
But is this information信息
enough足夠 to make an arrest逮捕?
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但光這項資訊就夠逮捕人嗎?
04:11
Of course課程 not,
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當然不夠,
我們被要求做更深入的鑽研調查。
04:12
and we are asked to delve鑽研 deeper更深
with our investigation調查.
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04:16
So we found發現 out, also, the presence存在
of other two very interesting有趣 molecules分子.
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所以,我們也發現指紋中
還有兩種相當有意思的分子。
04:21
One is an antidepressant抗抑鬱劑,
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其中一種是抗抑鬱藥的分子,
另一種是非常特別的分子。
04:24
and one is a very special特別 molecule分子.
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只有在你同時喝酒
又吸食古柯鹼時,
04:26
It only forms形式 in your body身體
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04:28
if you drink alcohol
and consume消耗 cocaine可卡因 at the same相同 time.
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體內才會形成這種分子。
04:32
And alcohol is known已知 to potentiate使可能
the effects效果 of cocaine可卡因,
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已知酒精會加強古柯鹼的效果,
所以,這就暗示著一個人
04:36
so here, we now have a hint暗示
on the state of mind心神
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在犯下犯罪時的心理狀態。
04:41
of the individual個人
whilst同時 perpetrating偷梁換柱 the crime犯罪.
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04:45
We passed通過 this information信息 to the police警察,
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我們把這項資訊交給警方,
04:48
and they found發現 out that, actually其實,
Thomson湯姆森 is a drug藥物 addict癮君子,
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他們發現,湯姆森確實有毒癮,
他也有精神病的醫療病史,
04:52
and he also has a medical record記錄
for psychotic精神病 episodes發作,
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據推測,針對精神病
所開的藥物就是抗憂鬱藥。
04:56
for which哪一個 presumably想必
the antidepressant抗抑鬱劑 was prescribed規定.
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05:01
So now Thomson湯姆森 becomes
the more likely容易 suspect疑似.
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現在,湯姆森變成了
最可疑的嫌疑犯。
05:07
But the reality現實 is that I still don't know
where these molecules分子 are coming未來 from,
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但現實是,我仍然不知道
這些分子來自何處、
來自哪個指紋,
05:12
from which哪一個 fingerprint指紋,
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以及這兩個指紋是誰的。
05:14
and who those two fingerprints指紋 belong屬於 to.
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05:18
Fear恐懼 not.
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別怕。
質譜成像還能進一步協助我們。
05:19
Mass spectrometry imaging成像
can help us further進一步.
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05:22
In fact事實, the technology技術 is so powerful強大
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事實上,這項技術非常強大,
讓我們可以看到這些分子
位在指紋上的哪個地方。
05:26
that we can see where
these molecules分子 are on a fingerprint指紋.
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05:31
Like you see in this video視頻,
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如各位在這支影片中所見的,
每一個高峰都對應到一個質量,
05:33
every一切 single one of those peaks
corresponds對應 to a mass,
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每個質量對應到一個分子,
05:37
every一切 mass to a molecule分子,
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我們只要選擇每一個分子,
就能夠詢問軟體
05:39
and we can interrogate審問 the software軟件,
by selecting選擇 each of those molecules分子,
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這個分子出現在
指跡上的哪個地方。
05:44
as to where they are present當下
on a fingermark指痕.
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05:49
And some images圖片 are not very revealing揭示,
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有些影像無法透露很多,
有些比較好,
05:52
some are better,
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有些非常好。
05:53
some are really good.
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05:56
And we can create創建 multiple images圖片
of the same相同 mark標記 --
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我們能對同一個痕跡,
創造多重影像——
理論上,針對同一個指紋
可以創造出數百張影像——
06:01
in theory理論, hundreds數以百計 of images圖片
of the same相同 fingerprint指紋 --
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就看我們偵測到多少個分子。
06:05
for as many許多 of the molecules分子
that we have detected檢測.
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06:09
So step one ...
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所以,步驟一……
06:12
for overlapping重疊 fingerprints指紋, chances機會 are,
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對於重疊的指紋,有可能,
特別是它們是不同人的指紋時,
06:16
especially特別 if they come
from different不同 individuals個人,
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它們的分子組成是不相同的,
06:18
that the molecular分子 composition組成
is not identical相同,
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06:22
so let's ask the software軟件
to visualize想像 those unique獨特 molecules分子
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所以,咱們叫軟體來將
那些只出現在一個指跡中,
在另一個指跡中沒有的
獨特分子做視覺化呈現。
06:27
just present當下 in one fingermark指痕
and not in the other one.
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06:31
By doing so,
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藉由這個做法,
我們就能把兩個指紋輪廓分離開來。
06:33
that's how we can separate分離
the two ridge patterns模式.
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06:38
And this is really important重要
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這點很重要,
因為警方現在能夠辨識出
這兩個指紋當中有一個
06:40
because the police警察 now are able能夠
to identify鑑定 one of the two fingerprints指紋,
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符合凱蒂的指紋。
06:46
which哪一個 actually其實 corresponds對應 to Katie凱蒂.
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06:49
And they've他們已經 been able能夠 to say so
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他們之所以能肯定,
是因為他們將兩張個別的影像和
06:50
because they've他們已經 compared相比
the two separate分離 images圖片
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凱蒂死後取得的影像做比對。
06:53
with one taken採取 posthumously死後 from Katie凱蒂.
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06:56
So now, we can concentrate集中
on one fingerprint指紋 only --
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所以,現在,我們只要
專注在一個指紋即可——
兇手的指紋。
07:02
that of the killer's殺手.
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07:04
So then, step two ...
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接著,步驟二……
07:06
where are these three
molecules分子 that I've seen看到?
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我看見的這三種分子在哪裡?
07:10
Well, let's interrogate審問 the software軟件 --
show顯示 me where they are.
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嗯,咱們來問問軟體——
讓我看看它們在哪裡。
這麼做,
07:13
And by doing this,
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就只會呈現出殺手指紋的
07:15
only portions of the image圖片
of the killer's殺手 fingerprint指紋 show顯示 up.
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部分影像。
換言之,
07:21
In other words,
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只會呈現出在兇手的
指紋中才有的物質。
07:22
those substances物質 are only present當下
in the killer's殺手 print打印.
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07:29
So now our molecular分子 findings發現
start開始 matching匹配 very nicely很好
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現在,我們的分子發現,
開始與警方手上
關於湯姆森的情資很吻合了,
07:34
the police警察 intelligence情報 about Thomson湯姆森,
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那指紋很可能是他的。
07:37
should that fingerprint指紋 belong屬於 to him.
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07:40
But the reality現實 is that that print打印
is still not good enough足夠
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但現實是,那個指紋還是沒有
好到可以做指認。
07:44
to make an identification鑑定.
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步驟三:
07:46
Step three:
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既然我們可以針對同一個指紋
07:47
since以來 we can generate生成 hundreds數以百計 of images圖片
of the same相同 fingerprint指紋,
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產生出數百張影像,
我們為什麼不把它們疊起來?
07:54
why don't we superimpose疊加 them,
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藉由這麼做,
07:57
and by doing so,
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也許可以試著改善圖案的
連續性和清楚度。
07:58
try to improve提高 the rich豐富 pattern模式
of continuity連續性 and clarity明晰?
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這就是結果。
08:02
That's the result結果.
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08:04
Striking引人注目.
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很驚人。
我們現在有了一個
非常清楚的指紋影像,
08:05
We now have a very clear明確 image圖片
of the fingerprint指紋
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警方可以在資料庫中比對。
08:09
and the police警察 can run it
through通過 the database數據庫.
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比對的結果是湯姆森。
08:12
The match比賽 comes out to Thomson湯姆森.
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08:15
Thomson湯姆森 is our killer兇手.
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兇手就是湯姆森。
08:17
(Applause掌聲)
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(掌聲)
凱蒂、嫌犯,和犯罪情境
08:21
Katie凱蒂, the suspects犯罪嫌疑人 and the circumstances情況
of the crime犯罪 aren't real真實,
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都不是真實的,
但這個故事中的元素,
08:28
but the story故事 contains包含 elements分子
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是我們一直在處理的
真實警方案件的元素,
08:31
of the real真實 police警察 casework個案
we've我們已經 been confronted面對 with,
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這故事也混合了
我們能提供的情資——
08:36
and is a composite綜合 of the intelligence情報
that we can provide提供 --
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都是我們曾經提供給警方的。
08:39
that we have been able能夠
to provide提供 the police警察.
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08:43
And I'm really, really thrilled高興
that after nine years年份 of intense激烈 research研究,
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截至 2017 年,我們已經
做了九年的密集研究,
現在我很興奮
08:47
as of 2017,
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我們可以對警方調查有所貢獻。
08:49
we are able能夠 to contribute有助於
to police警察 investigations調查.
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08:53
Mine is no longer a dream夢想;
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對我來說這不再是個夢;
它是個目標。
08:56
it's a goal目標.
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08:57
We're going to do this wider更寬的 and wider更寬的,
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我們會把這研究做得更廣泛、
更大,
09:00
bigger and bigger,
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我們將會對嫌犯了解更多,
09:02
and we're going to know
more about the suspect疑似,
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我們將會建立一種容貌拼相。
09:05
and we're going to build建立 an identikit身份識別.
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09:08
I believe this is also a new era時代
for criminal刑事 profiling剖析.
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我相信這個時代是
犯罪側寫的新時代。
犯罪學家的工作
09:12
The work of the criminologist犯罪學家
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會需要用到專案來辨視行為模式,
09:14
draws on the expert專家 recognition承認
of behavioral行為的 patterns模式
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根據過去觀察,
屬於某種特定類型、
09:18
that have been observed觀察到的 before
to belong屬於 to a certain某些 type類型,
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特定側寫的行為模式。
09:22
to a certain某些 profile輪廓.
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09:23
As opposed反對 to this expert專家
but subjective主觀 evaluation評測,
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相對於這種主觀的專家評估,
我們在試著達到同樣的目的,
09:28
we're trying to do the same相同 thing,
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09:30
but from the molecular分子 makeup化妝
of the fingerprint指紋,
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但用的是指紋的分子組成,
這兩種方式能夠並行。
09:34
and the two can work together一起.
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09:36
I did say that molecules分子 are storytellers講故事的人,
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我說過,分子會說故事,
所以,關於你的健康、
09:39
so information信息 on your health健康,
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你的行為、你的生活方式、
你的日常慣例的所有資訊
09:42
your actions行動, your lifestyle生活方式,
your routines例程,
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通通都在指紋上,且可以取得。
09:46
they're all there,
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09:48
accessible無障礙 in a fingerprint指紋.
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09:51
And molecules分子 are
the storytellers講故事的人 of our secrets秘密
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分子會說出我們的秘密,
只需要觸碰一下。
09:56
in just a touch觸摸.
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09:58
Thank you.
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謝謝大家。
(觀眾)哇喔。
09:59
(Audience聽眾) Wow.
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10:01
(Applause掌聲)
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(掌聲)
Translated by Lilian Chiu
Reviewed by congmei Han

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ABOUT THE SPEAKER
Simona Francese - Analytical chemist
Simona Francese is a chemist by training who is passionate about forensics.

Why you should listen

Simona Francese is a Professor of Forensic and Bioanalytical Mass Spectrometry at Sheffield Hallam University in the UK. As she writes: "I have been fascinated by forensics since I was 17, and I was determined to pursue an educational route that eventually would enable me to contribute to secure societies. As always in life, nothing is straightforward. I enrolled in the chemistry course because it was the closest degree at the time that could lead me to where I wanted to be. I ended up doing a PhD and post-doctorate fellowships working with viruses and diseases. But I was always focused on my ultimate objective, and throughout I developed a strong expertise in mass spectrometry, which is an extremely versatile analytical technique. This was crucial.

"When I obtained my first lectureship, I had the freedom to build my own research, and I used mass spectrometry imaging to develop ways to profile individuals from their fingermarks, thus helping police with their investigations. What has the suspect been handling? What is their lifestyle? What did he do prior to or while committing the crime? These are some of the questions that the developed technology can answer, and we are working on providing additional information -- for example, on the pathological or pharmacological state of the individual, just from looking at their fingermark! A fantastic achievement for me, but the best accomplishment was keeping the focus for 14 years and remaining determined to finally be able to do what I have always been so passionate about."

More profile about the speaker
Simona Francese | Speaker | TED.com