ABOUT THE SPEAKER
Simona Francese - Analytical chemist
Simona Francese is a chemist by training who is passionate about forensics.

Why you should listen

Simona Francese is a Professor of Forensic and Bioanalytical Mass Spectrometry at Sheffield Hallam University in the UK. As she writes: "I have been fascinated by forensics since I was 17, and I was determined to pursue an educational route that eventually would enable me to contribute to secure societies. As always in life, nothing is straightforward. I enrolled in the chemistry course because it was the closest degree at the time that could lead me to where I wanted to be. I ended up doing a PhD and post-doctorate fellowships working with viruses and diseases. But I was always focused on my ultimate objective, and throughout I developed a strong expertise in mass spectrometry, which is an extremely versatile analytical technique. This was crucial.

"When I obtained my first lectureship, I had the freedom to build my own research, and I used mass spectrometry imaging to develop ways to profile individuals from their fingermarks, thus helping police with their investigations. What has the suspect been handling? What is their lifestyle? What did he do prior to or while committing the crime? These are some of the questions that the developed technology can answer, and we are working on providing additional information -- for example, on the pathological or pharmacological state of the individual, just from looking at their fingermark! A fantastic achievement for me, but the best accomplishment was keeping the focus for 14 years and remaining determined to finally be able to do what I have always been so passionate about."

More profile about the speaker
Simona Francese | Speaker | TED.com
TED2018

Simona Francese: Your fingerprints reveal more than you think

Filmed:
2,372,231 views

Our fingerprints are what make us unique -- but they're also home to a world of information hidden in molecules that reveal our actions, lifestyles and routines. In this riveting talk, chemist Simona Francese shows how she studies these microscopic traces using mass spectrometry, a technology that analyzes fingerprints in previously impossible detail, and demonstrates how this cutting-edge forensic science can help police catch criminals. (Note: This talk contains descriptions of sexual violence.)
- Analytical chemist
Simona Francese is a chemist by training who is passionate about forensics. Full bio

Double-click the English transcript below to play the video.

00:12
Do you ever stop and think,
during a romantic dinner,
0
972
4886
00:17
"I've just left my fingerprints
all over my wine glass."
1
5882
2892
00:20
(Laughter)
2
8798
1001
00:21
Or do you ever worry,
when you visit a friend,
3
9823
2845
00:24
about leaving a little piece of you behind
on every surface that you touch?
4
12692
4478
00:30
And even this evening,
5
18009
1334
00:31
have you paid any attention
to sit without touching anything?
6
19367
3856
00:36
Well, you're not alone.
7
24148
1587
00:37
Thankfully, criminals underestimate
the power of fingerprints, too.
8
25759
4245
00:42
And I'm not just talking about
the twisted parting of lines
9
30792
3329
00:46
that make our fingerprint unique.
10
34145
3108
00:49
I'm talking about
an entire world of information
11
37277
4295
00:53
hiding in a small, often invisible thing.
12
41596
3664
00:57
In fact, fingerprints
are made up of molecules
13
45718
2686
01:00
that belong to three classes:
14
48428
1743
01:02
sweat molecules that we all produce
in very different amounts ...
15
50195
4802
01:07
molecules that we introduce into our body
and then we sweat out
16
55021
4431
01:11
and molecules that we may contaminate
our fingertips with
17
59476
3564
01:15
when we come across substances
like blood, paint, grease,
18
63064
3691
01:18
but also invisible substances.
19
66779
1957
01:21
And molecules are
the storytellers of who we are
20
69326
4913
01:26
and what we've been up to.
21
74263
1630
01:28
We just need to have
the right technology to make them talk.
22
76492
5018
01:34
So let me take you on a journey
of unthinkable capabilities.
23
82006
5165
01:42
Katie has been raped
24
90528
2079
01:45
and her lifeless body has been found
in the woods three days later,
25
93762
4576
01:50
after her disappearance.
26
98362
1500
01:52
The police is targeting three suspects,
27
100577
2510
01:55
having narrowed down
the search from over 20 men
28
103111
3903
01:59
who had been seen
in that area on the same day.
29
107038
2657
02:02
The only piece of evidence
30
110914
1807
02:04
is two very faint,
overlapping fingerprints
31
112745
4630
02:09
on the tape that was found
wrapped around Katie's neck.
32
117399
3618
02:13
Often, faint and overlapping fingerprints
cannot help the police
33
121912
4636
02:18
to make an identification.
34
126572
1943
02:20
And until recently,
this might have been the end of the road,
35
128539
4350
02:25
but this is where
we can make the difference.
36
133886
2226
02:29
The tape is sent to our labs,
37
137109
2755
02:31
where we're asked to use
our cutting-edge technology
38
139888
2960
02:34
to help with the investigation.
39
142872
1860
02:38
And here, we use an existing form
40
146032
2587
02:40
of mass spectrometry imaging technology
41
148643
4660
02:45
that we have further developed and adapted
42
153327
2563
02:47
specifically for the molecular and imaging
analysis of fingerprints.
43
155914
5250
02:53
In essence, we fire
a UV laser at the print,
44
161936
3985
02:57
and we cause the desorption
of the molecules from the print,
45
165945
3857
03:01
ready to be captured
by the mass spectrometer.
46
169826
2875
03:05
Mass spectrometry measures
the weight of the molecules --
47
173708
3301
03:09
or as we say, the mass --
48
177033
2294
03:11
and those numbers that you see there,
they indicate that mass.
49
179351
4518
03:15
But more crucially,
50
183893
1638
03:17
they indicate who those molecules are --
51
185555
4455
03:22
whether I'm seeing paracetamol
52
190034
2117
03:24
or something more sinister,
forensically speaking.
53
192175
3625
03:28
We applied this technology
to the evidence that we have
54
196734
3016
03:31
and we found the presence
of condom lubricants.
55
199774
3828
03:36
In fact, we've developed protocols
that enable us to even suggest
56
204337
4628
03:40
what brand of condom might have been used.
57
208989
3293
03:45
So we pass this information to the police,
58
213097
2087
03:47
who, meanwhile,
have obtained a search warrant
59
215208
3406
03:50
and they found the same brand
of condom in Dalton's premises.
60
218638
5952
03:57
And with Dalton and Thomson
also having records for sexual assaults,
61
225199
5428
04:02
then it is Chapman that may become
the less likely suspect.
62
230651
4698
04:08
But is this information
enough to make an arrest?
63
236028
3039
04:11
Of course not,
64
239533
1151
04:12
and we are asked to delve deeper
with our investigation.
65
240708
2730
04:16
So we found out, also, the presence
of other two very interesting molecules.
66
244225
4735
04:21
One is an antidepressant,
67
249609
2444
04:24
and one is a very special molecule.
68
252077
2022
04:26
It only forms in your body
69
254123
2125
04:28
if you drink alcohol
and consume cocaine at the same time.
70
256272
4034
04:32
And alcohol is known to potentiate
the effects of cocaine,
71
260719
3850
04:36
so here, we now have a hint
on the state of mind
72
264593
4764
04:41
of the individual
whilst perpetrating the crime.
73
269381
3087
04:45
We passed this information to the police,
74
273198
2978
04:48
and they found out that, actually,
Thomson is a drug addict,
75
276200
4284
04:52
and he also has a medical record
for psychotic episodes,
76
280508
4230
04:56
for which presumably
the antidepressant was prescribed.
77
284762
3771
05:01
So now Thomson becomes
the more likely suspect.
78
289016
4777
05:07
But the reality is that I still don't know
where these molecules are coming from,
79
295463
5493
05:12
from which fingerprint,
80
300980
1746
05:14
and who those two fingerprints belong to.
81
302750
2973
05:18
Fear not.
82
306346
1271
05:19
Mass spectrometry imaging
can help us further.
83
307641
2815
05:22
In fact, the technology is so powerful
84
310763
3245
05:26
that we can see where
these molecules are on a fingerprint.
85
314032
5047
05:31
Like you see in this video,
86
319821
2051
05:33
every single one of those peaks
corresponds to a mass,
87
321896
3878
05:37
every mass to a molecule,
88
325798
2072
05:39
and we can interrogate the software,
by selecting each of those molecules,
89
327894
4941
05:44
as to where they are present
on a fingermark.
90
332859
3650
05:49
And some images are not very revealing,
91
337385
3073
05:52
some are better,
92
340482
1467
05:53
some are really good.
93
341973
2462
05:56
And we can create multiple images
of the same mark --
94
344459
4992
06:01
in theory, hundreds of images
of the same fingerprint --
95
349475
4087
06:05
for as many of the molecules
that we have detected.
96
353586
3058
06:09
So step one ...
97
357547
1572
06:12
for overlapping fingerprints, chances are,
98
360262
3985
06:16
especially if they come
from different individuals,
99
364271
2521
06:18
that the molecular composition
is not identical,
100
366816
3419
06:22
so let's ask the software
to visualize those unique molecules
101
370259
5083
06:27
just present in one fingermark
and not in the other one.
102
375366
3874
06:31
By doing so,
103
379875
1685
06:33
that's how we can separate
the two ridge patterns.
104
381584
3948
06:38
And this is really important
105
386490
1975
06:40
because the police now are able
to identify one of the two fingerprints,
106
388489
6025
06:46
which actually corresponds to Katie.
107
394538
2157
06:49
And they've been able to say so
108
397368
1493
06:50
because they've compared
the two separate images
109
398885
2603
06:53
with one taken posthumously from Katie.
110
401512
2681
06:56
So now, we can concentrate
on one fingerprint only --
111
404902
5193
07:02
that of the killer's.
112
410119
1857
07:04
So then, step two ...
113
412477
1991
07:06
where are these three
molecules that I've seen?
114
414968
2768
07:10
Well, let's interrogate the software --
show me where they are.
115
418250
3248
07:13
And by doing this,
116
421522
1660
07:15
only portions of the image
of the killer's fingerprint show up.
117
423206
6281
07:21
In other words,
118
429511
1404
07:22
those substances are only present
in the killer's print.
119
430939
5738
07:29
So now our molecular findings
start matching very nicely
120
437120
5220
07:34
the police intelligence about Thomson,
121
442364
2701
07:37
should that fingerprint belong to him.
122
445089
2489
07:40
But the reality is that that print
is still not good enough
123
448650
3647
07:44
to make an identification.
124
452321
2048
07:46
Step three:
125
454393
1401
07:47
since we can generate hundreds of images
of the same fingerprint,
126
455818
6664
07:54
why don't we superimpose them,
127
462506
2923
07:57
and by doing so,
128
465453
1153
07:58
try to improve the rich pattern
of continuity and clarity?
129
466630
3413
08:02
That's the result.
130
470067
1500
08:04
Striking.
131
472303
1402
08:05
We now have a very clear image
of the fingerprint
132
473729
3942
08:09
and the police can run it
through the database.
133
477695
2750
08:12
The match comes out to Thomson.
134
480469
2360
08:15
Thomson is our killer.
135
483839
1501
08:17
(Applause)
136
485364
3968
08:21
Katie, the suspects and the circumstances
of the crime aren't real,
137
489356
6747
08:28
but the story contains elements
138
496127
3549
08:31
of the real police casework
we've been confronted with,
139
499700
4347
08:36
and is a composite of the intelligence
that we can provide --
140
504071
3166
08:39
that we have been able
to provide the police.
141
507261
2531
08:43
And I'm really, really thrilled
that after nine years of intense research,
142
511089
4638
08:47
as of 2017,
143
515751
1961
08:49
we are able to contribute
to police investigations.
144
517736
3106
08:53
Mine is no longer a dream;
145
521462
2624
08:56
it's a goal.
146
524110
1500
08:57
We're going to do this wider and wider,
147
525958
2824
09:00
bigger and bigger,
148
528806
1297
09:02
and we're going to know
more about the suspect,
149
530127
3081
09:05
and we're going to build an identikit.
150
533232
1972
09:08
I believe this is also a new era
for criminal profiling.
151
536121
4739
09:12
The work of the criminologist
152
540884
1390
09:14
draws on the expert recognition
of behavioral patterns
153
542298
4085
09:18
that have been observed before
to belong to a certain type,
154
546407
3625
09:22
to a certain profile.
155
550056
1500
09:23
As opposed to this expert
but subjective evaluation,
156
551869
4447
09:28
we're trying to do the same thing,
157
556340
2331
09:30
but from the molecular makeup
of the fingerprint,
158
558695
3564
09:34
and the two can work together.
159
562283
1811
09:36
I did say that molecules are storytellers,
160
564812
2866
09:39
so information on your health,
161
567702
2539
09:42
your actions, your lifestyle,
your routines,
162
570265
4157
09:46
they're all there,
163
574446
1788
09:48
accessible in a fingerprint.
164
576258
2436
09:51
And molecules are
the storytellers of our secrets
165
579403
4436
09:56
in just a touch.
166
584813
1335
09:58
Thank you.
167
586706
1151
09:59
(Audience) Wow.
168
587881
1158
10:01
(Applause)
169
589063
3532

▲Back to top

ABOUT THE SPEAKER
Simona Francese - Analytical chemist
Simona Francese is a chemist by training who is passionate about forensics.

Why you should listen

Simona Francese is a Professor of Forensic and Bioanalytical Mass Spectrometry at Sheffield Hallam University in the UK. As she writes: "I have been fascinated by forensics since I was 17, and I was determined to pursue an educational route that eventually would enable me to contribute to secure societies. As always in life, nothing is straightforward. I enrolled in the chemistry course because it was the closest degree at the time that could lead me to where I wanted to be. I ended up doing a PhD and post-doctorate fellowships working with viruses and diseases. But I was always focused on my ultimate objective, and throughout I developed a strong expertise in mass spectrometry, which is an extremely versatile analytical technique. This was crucial.

"When I obtained my first lectureship, I had the freedom to build my own research, and I used mass spectrometry imaging to develop ways to profile individuals from their fingermarks, thus helping police with their investigations. What has the suspect been handling? What is their lifestyle? What did he do prior to or while committing the crime? These are some of the questions that the developed technology can answer, and we are working on providing additional information -- for example, on the pathological or pharmacological state of the individual, just from looking at their fingermark! A fantastic achievement for me, but the best accomplishment was keeping the focus for 14 years and remaining determined to finally be able to do what I have always been so passionate about."

More profile about the speaker
Simona Francese | Speaker | TED.com

Data provided by TED.

This site was created in May 2015 and the last update was on January 12, 2020. It will no longer be updated.

We are currently creating a new site called "eng.lish.video" and would be grateful if you could access it.

If you have any questions or suggestions, please feel free to write comments in your language on the contact form.

Privacy Policy

Developer's Blog

Buy Me A Coffee