ABOUT THE SPEAKER
Todd Kuiken - Biomedical engineer
A doctor and engineer, Todd Kuiken builds new prosthetics that connect with the human nervous system. Yes: bionics.

Why you should listen

As Dean Kamen said at TED2007, the design of the prosthetic arm hadn't really been updated since the Civil War -- basically "a stick and a hook." But at the Rehabilitation Institute of Chicago, physiatrist Todd Kuiken is building new arms and hands that are wired into the nervous system and can be controlled by the same impulses from the brain that once controlled flesh and blood.

Kuiken's training -- as both a physician and an engineer -- helps him see both sides of this complex problem. A technology called targeted muscle reinnervation uses nerves remaining after an amputation to control an artificial limb, linking brain impulses to a computer in the prosthesis that directs motors to move the limb. An unexpected effect in some patients: not only can they move their new limb, they can feel with it.

He  said: "From an engineering standpoint, this is the greatest challenge one can imagine: trying to restore the most incredible machine in the universe."

More profile about the speaker
Todd Kuiken | Speaker | TED.com
TEDGlobal 2011

Todd Kuiken: A prosthetic arm that "feels"

托德・库伊肯: 有触觉的假肢

Filmed:
964,029 views

作为理疗医生和工程师的托德・库伊肯造了一种可以与人体神经系统连接起来的假臂,从而提高运动能力,控制能力,甚至是触觉。病人阿曼达・济慈协助他在台上演示了下一代的假臂
- Biomedical engineer
A doctor and engineer, Todd Kuiken builds new prosthetics that connect with the human nervous system. Yes: bionics. Full bio

Double-click the English transcript below to play the video.

00:15
So today今天, I would like to talk with you
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今天,我想谈谈
00:18
about bionics仿生学,
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仿生学
00:20
which哪一个 is the popular流行 term术语
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仿生学被广泛用来
00:22
for the science科学 of replacing更换 part部分 of a living活的 organism生物
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描述用机械设备,或者机器人
00:25
with a mechatronic机电 device设备, or a robot机器人.
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来替代有机体组成部分的科学
00:28
It is essentially实质上
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实质上
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the stuff东东 of life meets符合 machine.
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它是生物和机器的交汇点
00:33
And specifically特别, I'd like to talk with you
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今天特别要说说的是
00:35
about how bionics仿生学 is evolving进化
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仿生学是怎样不断发展
00:38
for people with arm amputations截肢.
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来为手臂截肢病人服务的
00:41
This is our motivation动机.
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这是我们的动力
00:44
Arm amputation切断术 causes原因 a huge巨大 disability失能.
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手臂截肢带来极大不便
00:47
I mean, the functional实用 impairment减值 is clear明确.
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功能受损是毋庸置疑的
00:49
Our hands are amazing惊人 instruments仪器.
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我们的手是很奇妙的工具
00:51
And when you lose失去 one, far less both,
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当你失去一只手
00:54
it's a lot harder更难 to do the things
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日常生活
00:56
we physically物理 need to do.
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变得困难的多
00:58
There's also a huge巨大 emotional情绪化 impact碰撞.
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另外感情上的伤害也很大
01:00
And actually其实, I spend as much of my time in clinic诊所
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事实上,当我在诊所工作的时候
01:02
dealing交易 with the emotional情绪化 adjustment调整 of patients耐心
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我花在抚慰病人情感的时间
01:05
as with the physical物理 disability失能.
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几乎和治疗身体残疾一样多
01:07
And finally最后, there's a profound深刻 social社会 impact碰撞.
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最后,受部残疾还有很大的社会影响
01:10
We talk with our hands.
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我们用手势交谈
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We greet迎接 with our hands.
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用手打招呼
01:14
And we interact相互作用 with the physical物理 world世界 with our hands.
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我们通过手和世界交流
01:17
And when they're missing失踪,
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没有了手
01:19
it's a barrier屏障.
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这是个巨大障碍
01:21
Arm amputation切断术 is usually平时 caused造成 by trauma外伤,
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手部截肢通常是因为外伤
01:24
with things like industrial产业 accidents事故,
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比如工伤事故
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motor发动机 vehicle车辆 collisions碰撞
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汽车相撞
01:28
or, very poignantly尖锐, war战争.
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还有更揪心的 战争
01:30
There are also some children孩子 who are born天生 without arms武器,
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有些孩子出生就没有胳膊
01:33
called congenital先天性 limb deficiency不足.
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这叫先天性肢体缺失
01:36
Unfortunately不幸, we don't do great
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不幸的是
01:38
with upper-limb上肢 prosthetics假肢.
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上肢假体的发展不大
01:40
There are two general一般 types类型.
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这种假肢主要有两种
01:42
They're called body-powered体供电 prostheses假肢,
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被称为自身力源假肢
01:44
which哪一个 were invented发明 just after the Civil国内 War战争,
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这是美国南北战争之后不久发明的
01:46
refined精制 in World世界 War战争 I and World世界 War战争 IIII.
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在两次世界大战期间有所改进
01:49
Here you see a patent专利
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这是1912年的
01:51
for an arm in 1912.
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一个假臂的专利
01:53
It's not a lot different不同
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这跟我的病人使用的
01:55
than the one you see on my patient患者.
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没有多大区别
01:58
They work by harnessing治理 shoulder power功率.
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通过肩部力量驱动
02:00
So when you squish果酱 your shoulders肩膀, they pull on a bicycle自行车 cable电缆.
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当你扯动肩膀时 就带动了一个自行车缆线
02:03
And that bicycle自行车 cable电缆 can open打开 or close a hand or a hook
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这个自行车缆线就能收放手掌或者是钩子
02:06
or bend弯曲 an elbow弯头.
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或者弯曲手肘
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And we still use them commonly常用,
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我们仍广泛应用这些
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because they're very robust强大的
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因为这些装置很有力
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and relatively相对 simple简单 devices设备.
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也相对简单
02:14
The state of the art艺术
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目前最尖端的科技
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is what we call myoelectric肌电 prostheses假肢.
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是肌电假肢
02:18
These are motorized机动的 devices设备
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这种机械装置
02:20
that are controlled受控
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是通过
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by little electrical电动 signals信号 from your muscle肌肉.
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肌肉的微小电信号来控制
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Every一切 time you contract合同 a muscle肌肉,
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每当收缩肌肉的时候
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it emits发射 a little electricity电力
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它就发出微电流
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that you can record记录 with antennae天线 or electrodes电极
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可以通过天线或者电极接受
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and use that to operate操作 the motorized机动的 prosthesis假体.
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然后来控制机械臂
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They work pretty漂亮 well
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这个装置对
02:35
for people who have just lost丢失 their hand,
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只是刚失去手的人来说十分好用
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because your hand muscles肌肉 are still there.
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因为控制手的肌肉还在
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You squeeze your hand, these muscles肌肉 contract合同.
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握紧手 这里的肌肉就收缩
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You open打开 it, these muscles肌肉 contract合同.
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摊开手 这里的肌肉收缩
02:43
So it's intuitive直观的, and it works作品 pretty漂亮 well.
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完全是通过直觉产生的 效果很不错
02:46
Well how about with higher更高 levels水平 of amputation切断术?
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但是如果是高度截肢呢?
02:48
Now you've lost丢失 your arm above以上 the elbow弯头.
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一直截到手肘上方
02:50
You're missing失踪 not only these muscles肌肉,
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失去的就不仅是这些肌肉
02:52
but your hand and your elbow弯头 too.
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手和手肘都失去了
02:54
What do you do?
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这该怎么办呢?
02:56
Well our patients耐心 have to use
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病人就得通过
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very code-y代码-Y systems系统
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非常精密的系统
03:01
of using运用 just their arm muscles肌肉
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用上臂肌肉
03:03
to operate操作 robotic机器人 limbs四肢.
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来控制机械臂
03:06
We have robotic机器人 limbs四肢.
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机械臂有很多种
03:08
There are several一些 available可得到 on the market市场, and here you see a few少数.
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这是市面上常见的几种
03:11
They contain包含 just a hand that will open打开 and close,
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它包括一个可以收放的手
03:14
a wrist rotator and an elbow弯头.
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一个旋转手腕和一个肘部
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There's no other functions功能.
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没有其他功能了
03:18
If they did, how would we tell them what to do?
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那么怎样才能让手拥有原先的那些其他功能呢?
03:20
We built内置 our own拥有 arm at the Rehab康复 Institute研究所 of Chicago芝加哥
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我们在芝加哥的康复中心做了我们自己的假肢
03:23
where we've我们已经 added添加 some wrist flexion屈曲 and shoulder joints关节
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加入了几个手腕弯曲和肩膀关节
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to get up to six motors马达, or six degrees of freedom自由.
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有了六个机械部分 或者说有了六个自由度了
03:29
And we've我们已经 had the opportunity机会 to work with some very advanced高级 arms武器
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我们有幸操作了美军资助的
03:32
that were funded资助 by the U.S. military军事, using运用 these prototypes原型,
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一些先进假肢 有了这几个模型
03:35
that had up to 10 different不同 degrees of freedom自由
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我们得到了包括可活动手掌在内的
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including包含 movable活动 hands.
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10个自由度
03:40
But at the end结束 of the day,
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但是归根结底
03:42
how do we tell these robotic机器人 arms武器 what to do?
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怎么才能告诉这些机械手做什么呢?
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How do we control控制 them?
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怎么控制他们呢?
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Well we need a neural神经 interface接口,
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我们需要的是一个神经界面
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a way to connect to our nervous紧张 system系统
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一种能连接神经系统
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or our thought processes流程
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或者说思维过程的途径
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so that it's intuitive直观的, it's natural自然,
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这样才能变得像本能一样自然
03:54
like for you and I.
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像你我一样
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Well the body身体 works作品 by starting开始 a motor发动机 command命令 in your brain,
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身体是这样运作的:从大脑发出运动信号
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going down your spinal cord,
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信号通过脊椎
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out the nerves神经 and to your periphery周边.
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传给神经和边缘系统
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And your sensation's轰动的 the exact精确 opposite对面.
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而你的触觉的工作方式正好相反
04:07
You touch触摸 yourself你自己, there's a stimulus刺激物
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触碰自己 就有一个刺激
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that comes up those very same相同 nerves神经 back up to your brain.
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通过与原先一样的神经反射回大脑
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When you lose失去 your arm, that nervous紧张 system系统 still works作品.
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就算失去了手臂 神经系统还是可以工作的
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Those nerves神经 can put out command命令 signals信号.
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那些神经可以输出命令信号
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And if I tap龙头 the nerve神经 ending结尾
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如果碰一个二战老兵的
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on a World世界 War战争 IIII vet兽医,
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神经末端
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he'll地狱 still feel his missing失踪 hand.
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他仍然能感觉到失去的手
04:25
So you might威力 say,
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你也许会说
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let's go to the brain
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那就从大脑着手吧
04:29
and put something in the brain to record记录 signals信号,
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弄个设备记录大脑信号
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or in the end结束 of the peripheral外围设备 nerve神经 and record记录 them there.
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或者在边缘神经的末端用设备纪录
04:35
And these are very exciting扣人心弦 research研究 areas,
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这些都是令人振奋的研究领域
04:38
but it's really, really hard.
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但是非常非常艰难
04:40
You have to put in
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你得用上百条
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hundreds数以百计 of microscopic显微 wires电线
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微观结构的线路
04:44
to record记录 from little tiny individual个人 neurons神经元 -- ordinary普通 fibers纤维
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来记录非常细小的单个神经原-
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that put out tiny signals信号
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这些纤维能输出
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that are microvolts毫伏.
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只有微伏的微小信号
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And it's just too hard
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现在想在病人身上实现这个
04:54
to use now and for my patients耐心 today今天.
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还无比困难
04:56
So we developed发达 a different不同 approach途径.
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于是我们开发另外一条途径
04:59
We're using运用 a biological生物 amplifier放大器
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我们用一个生物放大器
05:02
to amplify放大 these nerve神经 signals信号 -- muscles肌肉.
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来放大神经信号-也就是肌肉
05:05
Muscles肌肉 will amplify放大 the nerve神经 signals信号
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肌肉能把神经信号
05:07
about a thousand-fold千倍,
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放大约一千倍
05:09
so that we can record记录 them from on top最佳 of the skin皮肤,
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这样我们就能在表皮检测到信号
05:12
like you saw earlier.
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就像你之前看到的
05:14
So our approach途径 is something we call targeted针对 reinnervation神经移植术.
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我们把这个方法称为定向神经移植术
05:17
Imagine想像, with somebody who's谁是 lost丢失 their whole整个 arm,
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试想一下 有人失去了整个手臂
05:20
we still have four major重大的 nerves神经
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但仍然还有
05:22
that go down your arm.
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四条主神经
05:24
And we take the nerve神经 away from your chest胸部 muscle肌肉
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我们从胸肌取出这些神经
05:27
and let these nerves神经 grow增长 into it.
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然后让其生长
05:30
Now you think, "Close hand," and a little section部分 of your chest胸部 contracts合同.
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你会想 “握手” 你胸肌的一小块就会收缩
05:33
You think, "Bend弯曲 elbow弯头,"
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你想“弯手肘”
05:35
a different不同 section部分 contracts合同.
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另一个部分就收缩
05:37
And we can use electrodes电极 or antennae天线
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我们能用电极或者天线
05:39
to pick that up and tell the arm to move移动.
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来接受信号然后让胳膊动起来
05:42
That's the idea理念.
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这就大体概念
05:44
So this is the first man that we tried试着 it on.
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这是我们尝试的第一个对象
05:47
His name名称 is Jesse杰西 Sullivan沙利文.
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他叫杰西・苏利文
05:49
He's just a saint of a man --
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他是了不起的人-
05:51
54-year-old-岁 lineman前锋 who touched感动 the wrong错误 wire线
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54岁的线路工人 不小心拿错了线
05:53
and had both of his arms武器 burnt so badly
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双臂严重烧伤
05:56
they had to be amputated截肢 at the shoulder.
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从肩部以下全部切除
05:58
Jesse杰西 came来了 to us at the RICRIC
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杰西来到芝加哥康复中心
06:00
to be fit适合 with these state-of-the-art最先进的 devices设备, and here you see them.
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与最先进的装备匹配
06:03
I'm still using运用 that old technology技术
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右边我仍然使用的
06:06
with a bicycle自行车 cable电缆 on his right side.
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自行车缆线的旧技术
06:08
And he picks精选 which哪一个 joint联合 he wants to move移动 with those chin下巴 switches开关.
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他用下巴那边的开关来控制关节移动
06:11
On the left side he's got a modern现代 motorized机动的 prosthesis假体
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左边是一个现代机械假臂
06:14
with those three joints关节,
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有三个关节
06:16
and he operates操作 little pads in his shoulder
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通过肩膀上的小垫子♪
06:19
that he touches触摸 to make the arm go.
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他触碰垫子来控制胳膊
06:21
And Jesse's杰西的 a good crane起重机 operator操作者,
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杰西能是个不错的吊车司机
06:23
and he did okay by our standards标准.
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按我们的标准他做得很不错了
06:25
He also required需要 a revision调整 surgery手术 on his chest胸部.
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他也要求在胸肌上实行修正手术
06:28
And that gave us the opportunity机会
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这给了我们一个机会
06:30
to do targeted针对 reinnervation神经移植术.
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来实行定向神经移植术
06:32
So my colleague同事, Dr博士. Greg格雷格 DumanianDumanian, did the surgery手术.
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我的同事格雷格・杜马尼安做了这个手术
06:35
First, we cut away the nerve神经 to his own拥有 muscle肌肉,
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首先取出连接到他自身肌肉的神经
06:38
then we took the arm nerves神经
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然后把胳膊神经
06:40
and just kind of had them shift转移 down onto his chest胸部
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放入胸腔里
06:42
and closed关闭 him up.
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然后缝合上
06:44
And after about three months个月,
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三个月后
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the nerves神经 grew成长 in a little bit and we could get a twitch抽搐.
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神经开始生长 肌肉能抽动了
06:48
And after six months个月, the nerves神经 grew成长 in well,
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六个月后 神经长得很好了
06:51
and you could see strong强大 contractions宫缩.
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可以看到很强烈的收缩
06:53
And this is what it looks容貌 like.
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就是这样的
06:55
This is what happens发生 when Jesse杰西 thinks
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杰西要收放手掌的话
06:57
open打开 and close his hand,
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或者弯曲手肘的话
06:59
or bend弯曲 or straighten弄直 your elbow弯头.
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就会是这样
07:02
You can see the movements运动 on his chest胸部,
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可以看到他胸肌的运动
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and those little hash哈希 marks分数
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皮肤上的标记
07:06
are where we put our antennae天线, or electrodes电极.
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指的是我们放天线或者电极的地方
07:08
And I challenge挑战 anybody任何人 in the room房间
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我想让诸位挑战一下
07:10
to make their chest胸部 go like this.
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看看是否有人能这么做
07:12
His brain is thinking思维 about his arm.
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他的大脑想的是手臂
07:14
He has not learned学到了 how to do this with the chest胸部.
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没有学过怎么控制胸肌
07:17
There is not a learning学习 process处理.
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这不是学习过程
07:19
That's why it's intuitive直观的.
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所以完全是本能的
07:21
So here's这里的 Jesse杰西 in our first little test测试 with him.
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下面是对杰西的第一个测试
07:24
On the left-hand左手 side, you see his original原版的 prosthesis假体,
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左手边是他原来的假臂
07:27
and he's using运用 those switches开关
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他用开关来把
07:29
to move移动 little blocks from one box to the other.
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小物块从一个盒子移到另一个
07:31
He's had that arm for about 20 months个月, so he's pretty漂亮 good with it.
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他装上那个假臂已有20个月 使用相当熟练
07:34
On the right side,
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在右边
07:36
two months个月 after we fit适合 him with his targeted针对 reinnervation神经移植术 prosthesis假体 --
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是装了定向神经移植假臂后的两个月-
07:39
which哪一个, by the way, is the same相同 physical物理 arm,
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这是同一个胳膊
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just programmed程序 a little different不同 --
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只是操控系统不一样了-
07:44
you can see that he's much faster更快
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可以看出来他移动小块
07:46
and much smoother平滑 as he moves移动 these little blocks.
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可以更快更顺畅
07:49
And we're only able能够 to use three of the signals信号 at this time.
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这里我们只用到了3个信号
07:52
Then we had one of those little surprises惊喜 in science科学.
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下面就是科学小惊喜了
07:57
So we're all motivated动机 to get motor发动机 commands命令
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我们的初衷都是用运动指令
07:59
to drive驾驶 robotic机器人 arms武器.
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来指挥机械臂
08:01
And after a few少数 months个月,
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几个月后
08:03
you touch触摸 Jesse杰西 on his chest胸部,
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触碰杰西的胸部
08:05
and he felt his missing失踪 hand.
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他能感觉到失去的手
08:08
His hand sensation感觉 grew成长 into his chest胸部 again
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他的手部触觉渐渐在胸部恢复
08:10
probably大概 because we had also taken采取 away a lot of fat脂肪,
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也许是因为我们取下了不少脂肪
08:13
so the skin皮肤 was right down to the muscle肌肉
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皮肤直接接触到肌肉
08:15
and deinnervateddeinnervated, if you would, his skin皮肤.
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神经生长起来
08:17
So you touch触摸 Jesse杰西 here, he feels感觉 his thumb拇指;
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如果你碰碰杰西这里 他惠感觉到手指
08:19
you touch触摸 it here, he feels感觉 his pinky小指.
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这里是小指
08:21
He feels感觉 light touch触摸
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他可以感受到从轻轻触碰
08:23
down to one gram公克 of force.
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到大概一克重量的触碰
08:25
He feels感觉 hot, cold, sharp尖锐, dull平淡,
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他能感受到热、冷、尖锐、钝
08:28
all in his missing失踪 hand,
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就如同他失去的手
08:30
or both his hand and his chest胸部,
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或者是手和胸同时感受到的
08:32
but he can attend出席 to either.
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但两者他都能注意到
08:34
So this is really exciting扣人心弦 for us,
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这让我们很兴奋
08:36
because now we have a portal门户,
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因为现在我们有办法
08:38
a portal门户, or a way to potentially可能 give back sensation感觉,
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有可能恢复触觉
08:42
so that he might威力 feel what he touches触摸
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这样他就通过假手
08:44
with his prosthetic假肢 hand.
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感觉物体
08:46
Imagine想像 sensors传感器 in the hand
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试想一下手上的感应器
08:48
coming未来 up and pressing紧迫 on this new hand skin皮肤.
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只要按压新的手部皮肤
08:51
So it was very exciting扣人心弦.
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这挺令人兴奋
08:53
We've我们已经 also gone走了 on
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同时针对
08:55
with what was initially原来 our primary population人口
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我们本来的主要研究人群——截肢至手肘上部人群的
08:57
of people with above-the-elbow上述的肘 amputations截肢.
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研究也进行着
08:59
And here we deinnervatedeinnervate, or cut the nerve神经 away,
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我们进行神经培养
09:02
just from little segments of muscle肌肉
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从很小的肌肉组织中切走神经
09:04
and leave离开 others其他 alone单独
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其它的不动
09:06
that give us our up-down上下 signals信号
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这样就有了指挥上下移动的信号
09:08
and two others其他 that will give us a hand open打开 and close signal信号.
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另外两个用于手的握紧张开信号
09:11
This was one of our first patients耐心, Chris克里斯.
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这是我们早期的病人中一位 克里斯
09:13
You see him with his original原版的 device设备
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左边是他原先的装置
09:15
on the left there after eight months个月 of use,
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使用了八个月
09:17
and on the right, it is two months个月.
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右边是两个月的(新装置)
09:19
He's about four or five times as fast快速
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有了这个他的行动速度
09:22
with this simple简单 little performance性能 metric.
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大概快了四到五倍
09:25
All right.
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好的
09:27
So one of the best最好 parts部分 of my job工作
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我工作最好的一部分
09:30
is working加工 with really great patients耐心
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是与非常棒的病人合作
09:32
who are also our research研究 collaborators合作者.
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他们也是我们研究的合作者
09:34
And we're fortunate幸运 today今天
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今天有幸
09:36
to have Amanda阿曼达 Kitts基茨 come and join加入 us.
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请来阿曼达・奇兹
09:38
Please welcome欢迎 Amanda阿曼达 Kitts基茨.
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欢迎阿曼达・奇兹
09:40
(Applause掌声)
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(掌声)
09:47
So Amanda阿曼达, would you please tell us how you lost丢失 your arm?
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阿曼达 能说说是怎么失去手臂的吗?
09:50
Amanda阿曼达 Kitts基茨: Sure. In 2006, I had a car汽车 accident事故.
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阿曼达・奇兹:好的。2006年的时候我出了场车祸
09:53
And I was driving主动 home from work,
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我下班开车回家
09:56
and a truck卡车 was coming未来 the opposite对面 direction方向,
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一辆卡车迎面而来
09:58
came来了 over into my lane车道,
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开进了我的车道
10:00
ran over the top最佳 of my car汽车 and his axle tore撕毁 my arm off.
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辗过我的车 车轴把我的胳膊扯了下来
10:04
Todd托德 Kuiken库伊肯: Okay, so after your amputation切断术, you healed愈合 up.
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托德・库伊肯:好的。截肢以后你恢复了健康
10:07
And you've got one of these conventional常规 arms武器.
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装了一个传统假臂
10:09
Can you tell us how it worked工作?
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能说说怎么使用的么?
10:12
AKAK: Well, it was a little difficult,
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AK:恩 有点困难
10:14
because all I had to work with was a bicep二头肌 and a tricep三头肌.
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因为我能使用的只是二头肌和肱三头肌
10:16
So for the simple简单 little things like picking选择 something up,
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所以如果我想拿起什么的话
10:19
I would have to bend弯曲 my elbow弯头,
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就得弯曲手肘
10:22
and then I would have to cocontractcocontract
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然后收缩
10:24
to get it to change更改 modes模式.
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来切换模式
10:26
When I did that,
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我要这么做
10:28
I had to use my bicep二头肌
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就得用上二头肌
10:31
to get the hand to close,
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来握紧手
10:33
use my tricep三头肌 to get it to open打开,
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三头肌来打开手
10:35
cocontractcocontract again
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然后共同收缩
10:37
to get the elbow弯头 to work again.
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来调动手肘
10:39
TKTK: So it was a little slow?
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TK:所以这样有点慢是吧?
10:41
AKAK: A little slow, and it was just hard to work.
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AK:有点慢,而且操作难。
10:44
You had to concentrate集中 a whole整个 lot.
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很费神
10:46
TKTK: Okay, so I think about nine months个月 later后来
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TK:那么九个月后
10:49
that you had the targeted针对 reinnervation神经移植术 surgery手术,
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你实行了神经移植手术
10:51
took six more months个月 to have all the reinnervation神经移植术.
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然后又花了六个月来生长神经
10:54
Then we fit适合 her with a prosthesis假体.
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然后我们为她装了一个假肢
10:57
And how did that work for you?
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这个效果如何呢?
10:59
AKAK: It works作品 good.
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AK:非常好
11:02
I was able能够 to use my elbow弯头
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我可以同时运用
11:06
and my hand simultaneously同时.
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手肘和手了
11:09
I could work them just by my thoughts思念.
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直接用思维控制
11:11
So I didn't have to do any of the cocontractingcocontracting and all that.
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这样我就不用集中精力去调动假肢
11:14
TKTK: A little faster更快?
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TK:快了些是吧?
11:16
AKAK: A little faster更快. And much more easy简单, much more natural自然.
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AK:快点了。而且方便,自然得多。
11:20
TKTK: Okay, this was my goal目标.
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TK:好的。这就是我的目标。
11:23
For 20 years年份, my goal目标 was to let somebody
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这20年间,我的目标就是让一些人
11:26
[be] able能够 to use their elbow弯头 and hand in an intuitive直观的 way
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能自然地同时使用
11:29
and at the same相同 time.
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手肘和手
11:31
And we now have over 50 patients耐心 around the world世界 who have had this surgery手术,
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目前在全世界有五十余人接受了这个手术
11:34
including包含 over a dozen of our wounded负伤 warriors勇士
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包括一些服役于美军
11:36
in the U.S. armed武装 services服务.
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负过伤的战士
11:38
The success成功 rate of the nerve神经 transfers转让 is very high.
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移植神经的成功率非常高
11:41
It's like 96 percent百分.
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大约是96%
11:43
Because we're putting a big fat脂肪 nerve神经 onto a little piece of muscle肌肉.
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因为我们把大量的神经放到一小块肌肉上
11:46
And it provides提供 intuitive直观的 control控制.
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并提供自然控制
11:50
Our functional实用 testing测试, those little tests测试,
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我们进行的功能小测试里
11:52
all show显示 that they're a lot quicker更快 and a lot easier更轻松.
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假肢都表现得更加快速、灵便
11:54
And the most important重要 thing
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最重要的是
11:56
is our patients耐心 have appreciated赞赏 it.
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我们的患者对此很满意
11:58
So that was all very exciting扣人心弦.
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所以这挺让人兴奋的
12:00
But we want to do better.
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不过我们希望做得更好
12:03
There's a lot of information信息 in those nerve神经 signals信号,
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神经的信号里有很多信息
12:07
and we wanted to get more.
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我们想要更多的信息
12:09
You can move移动 each finger手指. You can move移动 your thumb拇指, your wrist.
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能动手指,能动大拇指和手腕
12:12
Can we get more out of it?
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能做到这些吗?
12:14
So we did some experiments实验
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于是我们做了几个试验
12:16
where we saturated饱和的 our poor较差的 patients耐心 with zillions不计其数 of electrodes电极
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可怜的病人被安上了无数的电极
12:19
and then had them try to do two dozen different不同 tasks任务 --
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然后我们让他们做了二十多种不同的任务-
12:22
from wiggling摆动 a finger手指 to moving移动 a whole整个 arm
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从摆动手指到移动整个手臂
12:25
to reaching到达 for something --
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再到伸手够物体-
12:27
and recorded记录 this data数据.
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我们记录下数据
12:29
And then we used some algorithms算法
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并用了类似于
12:31
that are a lot like speech言语 recognition承认 algorithms算法,
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语音识别算法的算法
12:33
called pattern模式 recognition承认.
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我们称之模式识别
12:35
See.
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看了吧
12:37
(Laughter笑声)
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(笑声)
12:39
And here you can see, on Jesse's杰西的 chest胸部,
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这儿可以看到杰西的胸部
12:41
when he just tried试着 to do three different不同 things,
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当做三件不同的任务时
12:43
you can see three different不同 patterns模式.
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可以看到3种不同的模式
12:45
But I can't put in an electrode电极
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但是我不能放进一个电极说
12:47
and say, "Go there."
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“往那儿”
12:49
So we collaborated合作 with our colleagues同事 in University大学 of New Brunswick不伦瑞克,
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所以我们找了纽宾士大学的同事合作
12:52
came来了 up with this algorithm算法 control控制,
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写出了算法控制
12:54
which哪一个 Amanda阿曼达 can now demonstrate演示.
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阿曼达现在可以展示一下
12:56
AKAK: So I have the elbow弯头 that goes up and down.
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AK:我的手肘可以上下移动
13:01
I have the wrist rotation回转
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手腕可以转动
13:03
that goes -- and it can go all the way around.
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它能360度转动
13:06
And I have the wrist flexion屈曲 and extension延期.
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并且可以弯曲伸展
13:10
And I also have the hand closed关闭 and open打开.
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手掌也能收放
13:13
TKTK: Thank you, Amanda阿曼达.
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TK:谢谢。
13:15
Now this is a research研究 arm,
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这是个还在研究中的手臂
13:17
but it's made制作 out of commercial广告 components组件 from here down
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但从这里往下是我从四处搜罗来的市面上的组件
13:20
and a few少数 that I've borrowed from around the world世界.
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做成的
13:23
It's about seven pounds英镑,
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大概有7磅重
13:26
which哪一个 is probably大概 about what my arm would weigh称重
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要是我的胳膊从这儿断掉
13:28
if I lost丢失 it right here.
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差不多是这个重量
13:30
Obviously明显, that's heavy for Amanda阿曼达.
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但是很显然这对阿曼达来说很重
13:33
And in fact事实, it feels感觉 even heavier较重,
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事实上,感觉上会更重
13:35
because it's not glued胶合 on the same相同.
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因为连接的方式不一样
13:37
She's carrying携带 all the weight重量 through通过 harnesses吊带.
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她是通过吊带来承重
13:39
So the exciting扣人心弦 part部分 isn't so much the mechatronics机电一体化,
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所以机电一体化方面并不那么惊奇
13:42
but the control控制.
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而是控制上
13:44
So we've我们已经 developed发达 a small microcomputer微电脑
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我们开发了一个微型计算机
13:47
that is blinking闪烁 somewhere某处 behind背后 her back
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在她背上哪儿闪光
13:50
and is operating操作 this
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它能按照她调控的方式
13:52
all by the way she trains火车 it
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来操作使用
13:54
to use her individual个人 muscle肌肉 signals信号.
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她的单个肌肉信号
13:56
So Amanda阿曼达, when you first started开始 using运用 this arm,
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阿曼达,当你开始用这个假肢的时候
13:58
how long did it take to use it?
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花了多久?
14:01
AKAK: It took just about probably大概 three to four hours小时
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AK:大概三四个小时
14:03
to get it to train培养.
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来调试
14:05
I had to hook it up to a computer电脑,
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我得把它连到电脑上
14:07
so I couldn't不能 just train培养 it anywhere随地.
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不是随便哪里都能调试
14:09
So if it stopped停止 working加工, I just had to take it off.
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所以如果不运转了我只能拿下来
14:12
So now it's able能够 to train培养
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现在背上这个小件
14:14
with just this little piece on the back.
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就可以调试了
14:16
I can wear穿 it around.
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我可以带着到处走
14:18
If it stops停止 working加工 for some reason原因, I can retrain再培训 it.
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中途停止了也能继续
14:21
Takes about a minute分钟.
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只要一分钟就可以
14:23
TKTK: So we're really excited兴奋,
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TK:我们很兴奋
14:25
because now we're getting得到 to a clinically临床 practical实际的 device设备.
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因为这越来越接近可临床操作的器械了
14:28
And that's where our goal目标 is --
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而那就我们的目标-
14:30
to have something clinically临床 pragmatic务实 to wear穿.
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临床实用的假肢
14:34
We've我们已经 also had Amanda阿曼达 able能够 to use
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我们也让阿曼达使用
14:37
some of our more advanced高级 arms武器 that I showed显示 you earlier.
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之前向各位展示过的几个高级假肢
14:41
Here's这里的 Amanda阿曼达 using运用 an arm made制作 by DEKADEKA Research研究 Corporation公司.
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她现在带的是DEKA研究中心制作的假肢
14:44
And I believe Dean院长 Kamen假面 presented呈现 it at TEDTED a few少数 years年份 ago.
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我记得迪恩・卡门几年前在TED提到过
14:48
So Amanda阿曼达, you can see,
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这里可以看到阿曼达
14:50
has really good control控制.
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假肢的控制性非常好
14:52
It's all the pattern模式 recognition承认.
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这都是模式识别
14:54
And it now has a hand that can do different不同 grasps掌握.
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我们有假手可以做几种不同的抓取动作
14:57
What we do is have the patient患者 go all the way open打开
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我们就让患者自由尝试
15:00
and think, "What hand grasp把握 pattern模式 do I want?"
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然后思考:“我想要怎样的抓取模式?”
15:03
It goes into that mode模式,
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进入那么模式后
15:05
and then you can do up to five or six different不同 hand grasps掌握 with this hand.
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可以有五到六种不同的抓取模式
15:07
Amanda阿曼达, how many许多 were you able能够 to do with the DEKADEKA arm?
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阿曼达,你的DEKA手臂可以做几种?
15:10
AKAK: I was able能够 to get four.
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AK:四种
15:12
I had the key grip, I had a chuck夹头 grip,
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我有钥匙握,夹握
15:15
I had a power功率 grasp把握
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强力抓取
15:17
and I had a fine pinch.
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和精密捏取
15:19
But my favorite喜爱 one was just when the hand was open打开,
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但我最喜欢的是就这么摊着手
15:21
because I work with kids孩子,
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因为我和孩子们打交道
15:23
and so all the time you're clapping拍手 and singing唱歌,
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所以总是在唱歌或者拍手
15:26
so I was able能够 to do that again, which哪一个 was really good.
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现在我能做这些了真好
15:29
TKTK: That hand's手的 not so good for clapping拍手.
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TK:这个手拍手不怎么行
15:31
AKAK: Can't clap with this one.
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AK:这个不能拍手
15:33
TKTK: All right. So that's exciting扣人心弦
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TK:好的。
15:35
on where we may可能 go with the better mechatronics机电一体化,
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我们在机电一体化上不断发展
15:37
if we make them good enough足够
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如果我们做得足够好
15:39
to put out on the market市场 and use in a field领域 trial审讯.
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投放市场并提供试用,那就激动人心了
15:42
I want you to watch closely密切.
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下面请仔细观看
15:44
(Video视频) Claudia克劳迪娅: Oooooh哇,!
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(视频)克劳迪娅:哇!
15:46
TKTK: That's Claudia克劳迪娅,
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TK:这是克劳迪娅
15:48
and that was the first time
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这是她第一次
15:50
she got to feel sensation感觉 through通过 her prosthetic假肢.
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通过假肢感受触觉
15:53
She had a little sensor传感器 at the end结束 of her prosthesis假体
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假肢尾段有传感器
15:56
that then she rubbed over different不同 surfaces,
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把假肢在不同的表面上摩擦
15:59
and she could feel different不同 textures纹理
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她能感受到好几种
16:01
of sandpaper砂纸, different不同 grits, ribbon色带 cable电缆,
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砂纸,不同的粗燕麦粉,带状电缆
16:04
as it pushed on her reinnervated神经支配 hand skin皮肤.
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当假肢按压在移植神经的首部皮肤上
16:07
She said that when she just ran it across横过 the table,
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她说当她就在桌子上划来划去
16:10
it felt like her finger手指 was rocking摇摆.
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她能感受到手指的震动
16:12
So that's an exciting扣人心弦 laboratory实验室 experiment实验
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这是个令人振奋的试验
16:14
on how to give back, potentially可能, some skin皮肤 sensation感觉.
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对研究如何接受皮肤触觉很有意义
16:17
But here's这里的 another另一个 video视频 that shows节目 some of our challenges挑战.
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但另外一个视频展示了我们面临的一些挑战
16:20
This is Jesse杰西, and he's squeezing挤压 a foam泡沫 toy玩具.
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这是杰西,他正在捏一个泡沫玩具
16:23
And the harder更难 he squeezes挤压 -- you see a little black黑色 thing in the middle中间
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他捏得越紧-中间那个黑的
16:26
that's pushing推动 on his skin皮肤 proportional成比例的 to how hard he squeezes挤压.
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是用来测量捏紧的力度的
16:29
But look at all the electrodes电极 around it.
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但是看看那周围的电极
16:31
I've got a real真实 estate房地产 problem问题.
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我们有了个面积问题
16:33
You're supposed应该 to put a bunch of these things on there,
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我们应在那里放很多电极
16:35
but our little motor's电机 making制造 all kinds of noise噪声
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但是小马达在电极旁
16:38
right next下一个 to my electrodes电极.
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发出很大的噪声
16:40
So we're really challenged挑战 on what we're doing there.
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所以这些是我们的挑战
16:43
The future未来 is bright.
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未来是光明的
16:45
We're excited兴奋 about where we are and a lot of things we want to do.
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对于目前的状况和要做的事情我们很兴奋
16:48
So for example,
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比如
16:50
one is to get rid摆脱 of my real真实 estate房地产 problem问题
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一个是解决面积问题
16:53
and get better signals信号.
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优化信号
16:55
We want to develop发展 these little tiny capsules胶囊
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我们想开发出大概是
16:58
about the size尺寸 of a piece of risotto烩饭
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米粒大小的胶囊
17:00
that we can put into the muscles肌肉
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来植入肌肉
17:02
and telemeter遥测 out the EMG肌电图 signals信号,
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并使用遥控肌电信号
17:05
so that it's not worrying令人担忧 about electrode电极 contact联系.
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因为这能省掉电极装置
17:08
And we can have the real真实 estate房地产 open打开
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并且我们可以有富余面积
17:10
to try more sensation感觉 feedback反馈.
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用于触觉回传
17:12
We want to build建立 a better arm.
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我们还想做更好的手臂
17:14
This arm -- they're always made制作 for the 50th percentile百分 male --
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这个手臂-款式是为50%的男性制作的-
17:18
which哪一个 means手段 they're too big for five-eighths八分之五 of the world世界.
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也就是说对世界人口的八分之五来说都太大了
17:22
So rather than a super strong强大 or super fast快速 arm,
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所以相对于一个超级强壮或者敏捷的手臂
17:25
we're making制造 an arm that is --
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我们想做的
17:27
we're starting开始 with,
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首先是
17:29
the 25th percentile百分 female --
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25%的女性的-
17:32
that will have a hand that wraps包装 around,
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能够用来缠绕
17:34
opens打开 all the way,
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能完全摊开的手
17:36
two degrees of freedom自由 in the wrist and an elbow弯头.
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手腕和手肘有两个自由度
17:39
So it'll它会 be the smallest最少 and lightest最轻
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这将会是最小巧轻便
17:41
and the smartest最聪明的 arm ever made制作.
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并且是最智能的胳膊
17:43
Once一旦 we can do it that small,
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一旦我们能做出这么小的手
17:45
it's a lot easier更轻松 making制造 them bigger.
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再做大就容易了
17:47
So those are just some of our goals目标.
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这些是我们的几个目标
17:50
And we really appreciate欣赏 you all being存在 here today今天.
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很感谢各位的到场
17:54
I'd like to tell you a little bit about the dark黑暗 side,
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我想针对昨天的话题
17:56
with yesterday's昨天的 theme主题.
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说说不太阳光的一面
17:58
So Amanda阿曼达 came来了 jet-lagged喷射滞后,
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阿曼达在倒时差
18:00
she's using运用 the arm,
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她用假肢的时候
18:02
and everything goes wrong错误.
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出乱子了
18:04
There was a computer电脑 spook间谍,
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出现了个电脑故障
18:06
a broken破碎 wire线,
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一个线路断了
18:08
a converter变流器 that sparked引发.
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一个变频器烧了
18:10
We took out a whole整个 circuit电路 in the hotel旅馆
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我们在酒店了把整个线路板拆下来
18:12
and just about put on the fire alarm报警.
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就差要拉火警了
18:14
And none没有 of those problems问题 could I have dealt处理 with,
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这几个问题我一个都不会解决
18:17
but I have a really bright research研究 team球队.
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但是我有一个天才研究小组
18:19
And thankfully感激地 Dr博士. Annie安妮 Simon西蒙 was with us
446
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多亏安妮・西蒙博士的帮忙
18:22
and worked工作 really hard yesterday昨天 to fix固定 it.
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昨天费了很大力气修好了
18:24
That's science科学.
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这就是科学
18:26
And fortunately幸好, it worked工作 today今天.
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幸运的 今天照常运转
18:28
So thank you very much.
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非常感谢
18:30
(Applause掌声)
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(掌声)
Translated by Chunxiang Qian
Reviewed by Qi Gu

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ABOUT THE SPEAKER
Todd Kuiken - Biomedical engineer
A doctor and engineer, Todd Kuiken builds new prosthetics that connect with the human nervous system. Yes: bionics.

Why you should listen

As Dean Kamen said at TED2007, the design of the prosthetic arm hadn't really been updated since the Civil War -- basically "a stick and a hook." But at the Rehabilitation Institute of Chicago, physiatrist Todd Kuiken is building new arms and hands that are wired into the nervous system and can be controlled by the same impulses from the brain that once controlled flesh and blood.

Kuiken's training -- as both a physician and an engineer -- helps him see both sides of this complex problem. A technology called targeted muscle reinnervation uses nerves remaining after an amputation to control an artificial limb, linking brain impulses to a computer in the prosthesis that directs motors to move the limb. An unexpected effect in some patients: not only can they move their new limb, they can feel with it.

He  said: "From an engineering standpoint, this is the greatest challenge one can imagine: trying to restore the most incredible machine in the universe."

More profile about the speaker
Todd Kuiken | Speaker | TED.com

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