Rebecca Brachman: A new class of drug that could prevent depression and PTSD
Rebecca Brachman: Újfajta gyógyszer, amely megelőzheti a depressziót és a PTSD-t
Rebecca Brachman is a pioneer in the field of preventative psychopharmacology, developing drugs to enhance stress resilience and prevent mental illness. Full bio
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were made from, of all things,
rakétahajtóanyagból készültek.
one in five soldiers develop depression,
a katonák ötödénél alakul ki depresszió,
vagy mind a kettő.
that are at high risk for these diseases.
nagy a kialakulás esélye.
cancer patients, aid workers, refugees --
betegeknél, önkénteseknél, menekülteknél,
or major life stress.
stresszhelyzetet élt át.
these disorders are,
if they work at all,
discovered the first vaccine --
felfedezte az első oltást,
a prophylactic for a disease,
fel a betegség megelőzésére,
előzni a betegséget.
to extend to psychiatric diseases.
nem lehet megelőzni.
accidentally discovered
fedeztük fel az első gyógyszert,
depression and PTSD.
a depressziót és a PTSD-t.
whether they work in humans.
hogy embereken is működik-e.
psychopharmaceuticals
a stressznek való ellenálló képességet,
stress resilience,
that you've since recovered from.
amelyből azóta már felépültünk.
you missed a flight.
vagy lekésett repülőjárat.
is the active biological process
aktív biológiai folyamat,
to bounce back after stress.
hogy talpra álljunk a stressz után.
and your immune system fights it off.
és az immunrendszerünk leküzdi a kórt.
enough stressor,
such as depression.
of major depressive disorder
against purely biological stressors,
nyújtanak a tiszta biológiai stresszorok,
like bullying and isolation.
pl. a zaklatás és kirekesztés ellen.
of stress hormones.
stresszhormont adtunk.
without a psychological component.
pszichológiai összetevő nélkül.
of antidepressant treatment beforehand,
antidepresszáns kezelést alkalmazunk,
enhancer given a week before
növelőt adunk be egy héttel előbb,
the depressive behavior.
a drug has ever been shown
a stressz negatív hatásait.
often lifelong, clinical diseases.
gyakran életre szóló súlyos betegségek.
of substance abuse, homelessness,
kialakulásának, a hajléktalanná válás,
és az öngyilkosság kockázatát.
is over three trillion dollars per year.
több mint 3 billió dollár évente.
where we know someone is predictively
súlyos stresszt fog átélni.
to extreme stress.
going into an earthquake zone.
tartó vöröskeresztes önkéntes.
of a resilience enhancer
pirulát vagy injekciót adhatnánk neki
by looters or worse,
vagy még rosszabb történik vele,
against developing depression or PTSD
a depressziótól vagy PTSD-től
from experiencing the stress,
her susceptibility to depression and PTSD,
és PTSD-ra való érzékenységet,
her home, her family or even her life.
családja vagy az élete elvesztését.
the smallpox vaccine,
was widely available.
szélesebb körben elterjedjen.
sensitive and creative and empathetic.
kreatívabbak és empatikusabbak lesznek.
by constitution and not biology.
nem biológiai.
today about depression.
manapság a depresszióról is.
opened the door
that followed after,
feltárására adnak lehetőséget:
open the possibility of a whole new field:
choose to do with it.
mit kezdünk vele.
ABOUT THE SPEAKER
Rebecca Brachman - Neuroscientist, writer, entrepreneurRebecca Brachman is a pioneer in the field of preventative psychopharmacology, developing drugs to enhance stress resilience and prevent mental illness.
Why you should listen
Current treatments for mood disorders only suppress symptoms without addressing the underlying disease, and there are no known cures. The drugs Rebecca Brachman is developing would be the first to prevent psychiatric disorders such as post-traumatic stress disorder (PTSD) and depression.
Brachman completed her PhD at Columbia University, prior to which she was a fellow at the National Institutes of Health, where she discovered that immune cells carry a memory of psychological stress and that white blood cells can act as antidepressants and resilience-enhancers. Brachman's research has been featured in The Atlantic, WIRED and Business Insider, and her work was recently described by Dr. George Slavich on NPR as a "moonshot project that is very much needed in the mental health arena."
In addition to conducting ongoing research at Columbia, Brachman is an NYCEDC Entrepreneurship Lab Fellow and cofounder of Paravax -- a biotech startup developing vaccine-like prophylactic drugs ("paravaccines") -- along with her scientific collaborator, Christine Ann Denny. She is also working on a non-profit venture to repurpose existing generic drugs for use as prophylactics, and previously served as the Interim Program Director for Outreach at the Zuckerman Institute at Columbia University.
Brachman is also a playwright and screenwriter. She holds Bachelor's degrees in both neuroscience and creative wWriting, and she is currently working on a tech-focused writing project with her long-time writing partner, Sean Calder ("Grimm," "Damages," "ER"). She served as the director of NeuWrite, a national network of science-writing groups that fosters ongoing collaboration between scientists, writers and artists, and she has been featured as a storyteller at The Story Collider.
(Photo: Kenneth Willardt)
Rebecca Brachman | Speaker | TED.com