Rebecca Brachman: A new class of drug that could prevent depression and PTSD
Рэбекка Брахман: Депрессия мен стрессті емдеп жазатын жаңа дәрі
Rebecca Brachman is a pioneer in the field of preventative psychopharmacology, developing drugs to enhance stress resilience and prevent mental illness. Full bio
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were made from, of all things,
зымыран отынынан
жасалды дегенге сену қиын.
one in five soldiers develop depression,
жарақаттан соңғы стресстен,
немесе екеуінен де зардап шегеді.
that are at high risk for these diseases.
cancer patients, aid workers, refugees --
қызметкерлері, қатерлі ісігі барлар,
or major life stress.
кез келген жан шалдығады.
these disorders are,
жиі кездессе де,
if they work at all,
discovered the first vaccine --
вакцинаны ойлап тапты.
a prophylactic for a disease,
тауып қана қойған жоқ,
to extend to psychiatric diseases.
емдейді дегенге ешкім сенбеді.
accidentally discovered
depression and PTSD.
жаңа дәріні кездейсоқ тапқанға дейін
whether they work in humans.
әсерін зерттеудеміз.
psychopharmaceuticals
stress resilience,
деп атаймыз.
that you've since recovered from.
бір оқиғаны еске түсіріңізші.
you missed a flight.
тіпті ұшаққа кешігіп қалу...
is the active biological process
белсенді биологиялық процесс,
to bounce back after stress.
and your immune system fights it off.
күресі сияқты.
enough stressor,
such as depression.
психиатриялық ауру тудырады.
of major depressive disorder
байқағанымыз,
against purely biological stressors,
дәрілеріміз биологиялық факторларға,
like bullying and isolation.
факторларға да төтеп береді.
of stress hormones.
еккен мысалымызды айтайын.
without a psychological component.
таза биологиялық фактор деуге болады.
of antidepressant treatment beforehand,
антидепресанттардың да
enhancer given a week before
өзіміз жасаған дәріні бергенде
the depressive behavior.
a drug has ever been shown
often lifelong, clinical diseases.
бойына созылатын клиникалық аурулар.
of substance abuse, homelessness,
суицид қаупін арттырады.
is over three trillion dollars per year.
жылына үш триллион доллар жұмсайды.
where we know someone is predictively
to extreme stress.
going into an earthquake zone.
зілзала болған аймаққа аттанды.
of a resilience enhancer
by looters or worse,
да қауіпті адамдар ұстап алса,
against developing depression or PTSD
кейін ол оқиғаны еске алып
from experiencing the stress,
мүлдем ұшырамайды деген сөз емес,
her susceptibility to depression and PTSD,
сезімталдығын айтарлықтай төмендетеміз,
her home, her family or even her life.
өмірден безінбеуіне жағдай жасаймыз.
the smallpox vaccine,
was widely available.
sensitive and creative and empathetic.
деген қоғамдық пікір қалыптасқан еді.
by constitution and not biology.
жаратылыс жазады деп сенді.
today about depression.
пікірлер қалыптасқан.
opened the door
that followed after,
open the possibility of a whole new field:
психофармакотерапияның алдын алады да,
choose to do with it.
шешіп береді.
ABOUT THE SPEAKER
Rebecca Brachman - Neuroscientist, writer, entrepreneurRebecca Brachman is a pioneer in the field of preventative psychopharmacology, developing drugs to enhance stress resilience and prevent mental illness.
Why you should listen
Current treatments for mood disorders only suppress symptoms without addressing the underlying disease, and there are no known cures. The drugs Rebecca Brachman is developing would be the first to prevent psychiatric disorders such as post-traumatic stress disorder (PTSD) and depression.
Brachman completed her PhD at Columbia University, prior to which she was a fellow at the National Institutes of Health, where she discovered that immune cells carry a memory of psychological stress and that white blood cells can act as antidepressants and resilience-enhancers. Brachman's research has been featured in The Atlantic, WIRED and Business Insider, and her work was recently described by Dr. George Slavich on NPR as a "moonshot project that is very much needed in the mental health arena."
In addition to conducting ongoing research at Columbia, Brachman is an NYCEDC Entrepreneurship Lab Fellow and cofounder of Paravax -- a biotech startup developing vaccine-like prophylactic drugs ("paravaccines") -- along with her scientific collaborator, Christine Ann Denny. She is also working on a non-profit venture to repurpose existing generic drugs for use as prophylactics, and previously served as the Interim Program Director for Outreach at the Zuckerman Institute at Columbia University.
Brachman is also a playwright and screenwriter. She holds Bachelor's degrees in both neuroscience and creative wWriting, and she is currently working on a tech-focused writing project with her long-time writing partner, Sean Calder ("Grimm," "Damages," "ER"). She served as the director of NeuWrite, a national network of science-writing groups that fosters ongoing collaboration between scientists, writers and artists, and she has been featured as a storyteller at The Story Collider.
(Photo: Kenneth Willardt)
Rebecca Brachman | Speaker | TED.com