ABOUT THE SPEAKER
Talithia Williams - Statistician
Talithia Williams builds statistical models that study the spatial and temporal structure of data.

Why you should listen

Dr. Talithia Williams is an Associate Professor of Mathematics at Harvey Mudd College. Her professional experiences include research appointments at the Jet Propulsion Laboratory (JPL), the National Security Agency (NSA), and NASA. Dr. Williams develops statistical models that emphasize the spatial and temporal structure of data with environmental applications. She has been recognized for the development of a cataract model used to predict the cataract surgical rate for developing countries in Africa.

In addition to her academic accomplishments, Dr. Williams and her husband, Donald, actively teach and share foundational principles regarding the joys of Christian marriage. Dr. Williams’ talk will explore how each of us can begin to collect data about ourselves that can provide insight into our personal health.

More profile about the speaker
Talithia Williams | Speaker | TED.com
TEDxClaremontColleges

Talithia Williams: Own your body's data

Filmed:
1,717,214 views

The new breed of high-tech self-monitors (measuring heartrate, sleep, steps per day) might seem targeted at competitive athletes. But Talithia Williams, a statistician, makes a compelling case that all of us should be measuring and recording simple data about our bodies every day — because our own data can reveal much more than even our doctors may know.
- Statistician
Talithia Williams builds statistical models that study the spatial and temporal structure of data. Full bio

Double-click the English transcript below to play the video.

00:12
As a kid I always loved information
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that I could get from data
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and the stories that could be told with numbers.
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I remember, growing up, I'd be frustrated at
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how my own parents would lie to me using numbers.
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"Talithia, if I've told you once
I've told you a thousand times."
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No dad, you've only told me 17 times
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and twice it wasn't my fault. (Laughter)
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I think that is one of the reasons I got a Ph.D. in statistics.
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I always wanted to know,
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what are people trying to hide with numbers?
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As a statistician,
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I want people to show me the data
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so I can decide for myself.
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Donald and I were pregnant with our third child
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and we were at about 41 and a half weeks,
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what some of you may refer to as being overdue.
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Statisticians, we call that
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being within the 95 percent confidence interval.
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(Laughter)
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And at this point in the process
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we had to come in every couple of days
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to do a stress test on the baby,
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and this is just routine,
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it tests whether or not the baby
is feeling any type of undue stress.
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01:22
And you are rarely, if ever, seen by your actual doctor,
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just whoever happens to be
working at the hospital that day.
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So we go in for a stress test and after 20 minutes
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the doctor comes out and he says,
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"Your baby is under stress, we need to induce you."
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Now, as a statistician, what's my response?
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Show me the data!
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So then he proceeds to tell us
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the baby's heart rate trace went from 18 minutes,
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the baby's heart rate was in the normal zone
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and for two minutes it was in what appeared to be
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my heart rate zone and I said,
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"Is it possible that maybe this was my heart rate?
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I was moving around a little bit,
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it's hard to lay still on your back,
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41 weeks pregnant for 20 minutes.
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Maybe it was shifting around."
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He said, "Well, we don't want to take any chances."
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I said okay.
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I said, "What if I was at 36 weeks
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with this same data?
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Would your decision be to induce?"
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"Well, no, I would wait until you were at least
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38 weeks, but you are almost 42,
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there is no reason to leave that baby inside,
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let's get you a room."
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I said, "Well, why don't we just do it again?
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We can collect more data.
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I can try to be really still for 20 minutes.
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We can average the two and see
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what that means. (Laughter)
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And he goes,
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"Ma'am, I just don't want you to have a miscarriage."
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That makes three of us.
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And then he says,
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"Your chances of having a miscarriage double
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when you go past your due date. Let's get you a room."
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Wow. So now as a statistician, what's my response?
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Show me the data!
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Dude, you're talking chances,
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I do chances all day long, tell me all about chances.
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Let's talk chances. (Laughter)
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Let's talk chances.
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So I say, "Okay, great.
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Do I go from a 30-percent
chance to a 60-percent chance?
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Where are we here with this miscarriage thing?
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And he goes, "Not quite, but it doubles,
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and we really just want what's best for the baby."
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Undaunted, I try a different angle.
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I said, "Okay, out of 1,000 full-term pregnant women,
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how many of them are going to miscarry
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just before their due date?
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And then he looks at me and looks at Donald,
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and he goes, about one in 1,000.
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I said, "Okay, so of those 1,000 women, how many
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are going to miscarry just after their due date?"
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"About two." (Laughter)
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I said, "Okay, so you are telling me that my chances
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go from a 0.1-percent chance
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to a 0.2-percent chance."
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Okay, so at this point the data is not convincing us
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that we need to be induced,
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and so then we proceed to have a conversation
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about how inductions lead to a higher rate
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of Cesarean sections, and if at all
possible we'd like to avoid that.
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And then I said,
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"And I really don't think my due date is accurate."
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(Laughter)
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And so this really stunned him
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and he looked sort of puzzled
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and I said, "You may not know this,
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but pregnancy due dates are calculated
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assuming that you have a standard 28-day cycle,
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and my cycle ranges —
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sometimes it's 27, sometimes it's up to 38 —
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and I have been collecting the data to prove it.
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(Laughter)
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And so we ended up leaving the hospital
that day without being induced.
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We actually had to sign a waiver
to walk out of the hospital.
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And I'm not advocating that you not listen to your doctors,
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because even with our first child,
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we were induced at 38 weeks; cervical fluid was low.
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I'm not anti-medical intervention.
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But why were confident to leave that day?
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Well, we had data that told a different story.
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We had been collecting data for six years.
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I had this temperature data,
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and it told a different story.
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In fact, we could probably pretty
accurately estimate conception.
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Yeah, that's a story you want to tell
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at your kid's wedding reception. (Laughter)
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I remember like it was yesterday.
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My temperature was a sizzling 97.8 degrees
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as I stared into your father's eyes. (Laughter)
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Oh, yeah. Twenty-two more years, we're telling that story.
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But we were confident to leave
because we had been collecting data.
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Now, what does that data look like?
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Here's a standard chart
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of a woman's waking body temperature
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during the course of a cycle.
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So from the beginning of the menstrual cycle
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till the beginning of the next.
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You'll see that the temperature is not random.
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Clearly there is a low pattern
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at the beginning of her cycle
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and then you see this jump and then a higher
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set of temperatures at the end of her cycle.
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So what's happening here?
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What is that data telling you?
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Well, ladies, at the beginning of our cycle,
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the hormone estrogen is dominant and that estrogen
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causes a suppression of your body temperature.
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And at ovulation, your body releases an egg
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and progesterone takes over, pro-gestation.
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And so your body heats up in anticipation
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of housing this new little fertilized egg.
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So why this temperature jump?
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Well, think about when a bird sits on her eggs.
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Why is she sitting on them?
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She wants to keep them warm,
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protect them and keep them warm.
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Ladies, this is exactly what our bodies do every month,
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they heat up in anticipation
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of keeping a new little life warm.
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And if nothing happens, if you are not pregnant,
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then estrogen takes back over and
that cycle starts all over again.
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But if you do get pregnant, sometimes you
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actually see another shift in your temperatures
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and it stays elevated for those whole nine months.
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That's why you see those pregnant
women just sweating and hot,
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because their temperatures are high.
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Here's a chart that we had about three or four years ago.
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We were really very excited about this chart.
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You'll see the low temperature level
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and then a shift and for about five days,
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that's about the time it takes for the egg to travel
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down the fallopian tube and implant,
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and then you see those temperatures
start to go up a little bit.
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And in fact, we had a second temperature shift,
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confirmed with a pregnancy test
that were indeed pregnant
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with our first child, very exciting.
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Until a couple of days later
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I saw some spotting and then I noticed heavy blood flow,
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and we had in fact had an early stage miscarriage.
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Had I not been taking my temperature
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I really would have just thought
my period was late that month,
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but we actually had data to show
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that we had miscarried this baby,
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and even though this data revealed a really
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unfortunate event in our lives,
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it was information that we could then take to our doctor.
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So if there was a fertility issue or some problem,
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I had data to show:
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Look, we got pregnant, our temperature shifted,
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we somehow lost this baby.
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What is it that we can do to help prevent this problem?
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And it's not just about temperatures
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and it's not just about fertility;
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we can use data about our bodies to tell us a lot of things.
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For instance, did you know that taking
your temperature can tell you a lot
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about the condition of your thyroid?
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So, your thyroid works a lot like
the thermostat in your house.
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There is an optimal temperature
that you want in your house;
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you set your thermostat.
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When it gets too cold in the house,
your thermostat kicks in
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and says, "Hey, we need to blow some heat around."
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Or if it gets too hot, your thermostat
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registers, "Turn the A.C. on. Cool us off."
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That's exactly how your thyroid works in your body.
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Your thyroid tries to keep an optimal temperature
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for your body.
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If it gets too cold, your thyroid
says, "Hey, we need to heat up."
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If it gets too hot, your thyroid cools you down.
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But what happens when your
thyroid is not functioning well?
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When it doesn't function, then it shows up
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in your body temperatures,
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they tend to be lower than normal or very erratic.
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And so by collecting this data
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you can find out information about your thyroid.
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Now, what is it, if you had a thyroid
problem and you went to the doctor,
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your doctor would actually test the amount of
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thyroid stimulating hormone in your blood.
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Fine. But the problem with that test is
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it doesn't tell you how active the hormone is in your body.
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So you might have a lot of hormone present,
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but it might not be actively working to regulate
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your body temperature.
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So just by collecting your temperature every day,
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you get information about the condition of your thyroid.
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So, what if you don't want to take
your temperature every day?
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I advocate that you do,
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but there are tons of other things you could take.
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You could take your blood pressure,
you could take your weight —
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yeah, who's excited about
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taking their weight every day? (Laughter)
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Early on in our marriage, Donald had a stuffy nose
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and he had been taking a slew of medications
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to try to relieve his stuffy nose, to no avail.
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And so, that night he comes and
he wakes me up and he says,
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"Honey, I can't breath out of my nose."
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And I roll over and I look, and I said,
"Well, can you breath out of your mouth?"
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(Laughter)
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And he goes, "Yes, but I can't breath out of my nose!"
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And so like any good wife, I rush him
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to the emergency room
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at 2 o'clock in the morning.
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And the whole time I'm driving and I'm thinking,
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you can't die on me now.
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We just got married,
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people will think I killed you! (Laughter)
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And so, we get to the emergency
room, and the nurse sees us,
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and he can't breath out of his nose, and so
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she brings us to the back and the doctor says,
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"What seems to be the problem?" and
he goes, "I can't breath out of my nose."
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And he said, "You can't breath out of your nose?
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No, but he can breath out of his mouth. (Laughter)
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He takes a step back and he looks at both of us
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and he says "Sir, I think I know the problem.
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You're having a heart attack.
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I'm going to order an EKG and a CAT scan
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for you immediately."
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And we are thinking,
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no, no, no. It's not a heart attack. He can breathe,
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just out of his mouth. No, no, no, no, no.
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And so we go back and forth with this doctor
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because we think this is the incorrect diagnosis,
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and he's like, "No really, it'll be fine, just calm down."
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And I'm thinking, how do you calm down?
But I don't think he's having a heart attack.
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And so fortunately for us, this
doctor was at the end of the shift.
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So this new doctor comes in, he sees us clearly
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distraught, with a husband who can't breath
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out of his nose. (Laughter)
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And he starts asking us questions.
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He says, "Well, do you two exercise?"
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We ride our bikes, we go to the gym occasionally.
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(Laughter)
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We move around.
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And he says, "What were you doing
just before you came here?"
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I'm thinking, I was sleeping, honestly.
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But okay, what was Donald doing just before?
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So Donald goes into this slew
of medications he was taking.
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He lists, "I took this decongestant
and then I took this nasal spray,"
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and then all of a sudden a lightbulb goes off and he says,
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"Oh! You should never mix this
decongestant with this nasal spray.
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Clogs you up every time. Here, take this one instead."
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He gives us a prescription.
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13:35
We're looking at each other, and I looked at the doctor,
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and I said, "Why is it that it seems like you
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were able to accurately diagnose his condition,
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13:41
but this previous doctor wanted to order
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an EKG and a CAT scan?"
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And he looks at us and says,
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"Well, when a 350-pound man walks in the
emergency room and says he can't breath,
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you assume he's having a heart attack
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13:55
and you ask questions later."
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13:59
Now, emergency room doctors are
trained to make decisions quickly,
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but not always accurately.
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14:07
And so had we had some information
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14:08
about our heart health to share with him,
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14:10
maybe we would have gotten a
better diagnosis the first time.
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14:14
I want you to consider the following chart,
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14:16
of systolic blood pressure measurements
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1954
14:18
from October 2010 to July 2012.
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4072
14:22
You'll see that these measurements start
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1693
14:24
in the prehypertension/hypertension zone,
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3668
14:28
but over about the course of a year and a half
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2586
14:30
they move into the normal zone.
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2645
14:33
This is about the heart rate of a healthy 16-year-old.
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4109
14:37
What story is this data telling you?
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Obviously it's the data from someone
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14:44
who's made a drastic transformation,
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2673
14:47
and fortunately for us, that person
happens to be here today.
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14:52
So that 350-pound guy that walked
into the emergency room with me
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14:56
is now an even sexier and healthier
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14:59
225-pound guy, and that's his blood pressure trace.
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6688
15:06
So over the course of that year and a half
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15:09
Donald's eating changed
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1569
15:11
and our exercise regimen changed,
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1991
15:13
and his heart rate responded,
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2790
15:16
his blood pressure responded to that change
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15:17
that he made in his body.
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So what's the take-home message
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that I want you to leave with today?
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By taking ownership of your data just like we've done,
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15:30
just by taking this daily measurements about yourself,
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3947
15:33
you become the expert on your body.
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15:36
You become the authority.
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2002
15:38
It's not hard to do.
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15:40
You don't have to have a Ph.D. in statistics
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1920
15:42
to be an expert in yourself.
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15:44
You don't have to have a medical degree
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15:45
to be your body's expert.
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2126
15:47
Medical doctors, they're experts on the population,
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3419
15:51
but you are the expert on yourself.
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2278
15:53
And so when two of you come together,
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1910
15:55
when two experts come together,
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1970
15:57
the two of you are able to make a better decision
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2795
16:00
than just your doctor alone.
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2000
16:02
Now that you understand the power of information
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that you can get through personal data collection,
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16:07
I'd like you all to stand and raise your right hand.
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16:11
(Laughter)
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Yes, get it up.
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16:18
I challenge you to take ownership of your data.
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16:25
And today, I hereby confer upon you
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16:29
a TEDx associate's degree in elementary statistics
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16:33
with a concentration in time-dependent data analysis
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16:38
with all the rights and privileges appertaining thereto.
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3713
16:41
And so the next time you are in your doctor's office,
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as newly inducted statisticians,
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what should always be your response?
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Audience: Show me the data!
Talithia Williams: I can't hear you!
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Audience: Show me the data!
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TW: One more time!
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Audience: Show me the data!
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16:57
TW: Show me the data.
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Thank you.
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(Applause)
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ABOUT THE SPEAKER
Talithia Williams - Statistician
Talithia Williams builds statistical models that study the spatial and temporal structure of data.

Why you should listen

Dr. Talithia Williams is an Associate Professor of Mathematics at Harvey Mudd College. Her professional experiences include research appointments at the Jet Propulsion Laboratory (JPL), the National Security Agency (NSA), and NASA. Dr. Williams develops statistical models that emphasize the spatial and temporal structure of data with environmental applications. She has been recognized for the development of a cataract model used to predict the cataract surgical rate for developing countries in Africa.

In addition to her academic accomplishments, Dr. Williams and her husband, Donald, actively teach and share foundational principles regarding the joys of Christian marriage. Dr. Williams’ talk will explore how each of us can begin to collect data about ourselves that can provide insight into our personal health.

More profile about the speaker
Talithia Williams | Speaker | TED.com

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