Rebecca Brachman: A new class of drug that could prevent depression and PTSD
Ребекка Брахман: Новый класс препаратов, способных предотвратить депрессию и ПТСР
Rebecca Brachman is a pioneer in the field of preventative psychopharmacology, developing drugs to enhance stress resilience and prevent mental illness. Full bio
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were made from, of all things,
антидепрессанты были сделаны
после Второй мировой войны.
one in five soldiers develop depression,
каждый пятый солдат страдает от депрессии
that are at high risk for these diseases.
cancer patients, aid workers, refugees --
раком, гуманитарные работники, беженцы.
or major life stress.
these disorders are,
этих заболеваний,
if they work at all,
если они вообще работают,
discovered the first vaccine --
открыл первую вакцину,
a prophylactic for a disease,
профилактическое средство,
to extend to psychiatric diseases.
к психическим расстройствам.
accidentally discovered
мы с коллегой случайно не открыли
depression and PTSD.
предотвратить депрессию и ПТСР.
whether they work in humans.
psychopharmaceuticals
stress resilience,
противостоять стрессу,
усилителями стрессоустойчивости.
that you've since recovered from.
от которых вы уже оправились.
you missed a flight.
опоздание на самолёт.
is the active biological process
активный биологический процесс,
to bounce back after stress.
к нормальному состоянию.
and your immune system fights it off.
иммунной системы с простудой.
enough stressor,
such as depression.
например, депрессию.
of major depressive disorder
сильное депрессивное расстройство
against purely biological stressors,
справиться как с биологическими факторами,
like bullying and isolation.
как травля и изоляция.
of stress hormones.
высокому уровню гормона стресса.
without a psychological component.
фактору без психологической составляющей.
of antidepressant treatment beforehand,
трёхнедельный курс антидепрессантов,
enhancer given a week before
дозу усилителя стрессоустойчивости,
the depressive behavior.
депрессивное поведение.
a drug has ever been shown
обнаружена способность
последствия стресса.
often lifelong, clinical diseases.
они часто длятся всю жизнь.
of substance abuse, homelessness,
наркозависимым, бездомным,
болезни Альцгеймера, суициду.
is over three trillion dollars per year.
более трёх триллионов долларов в год.
where we know someone is predictively
человека, который рискует
to extreme stress.
going into an earthquake zone.
едет в зону землетрясений.
of a resilience enhancer
усилителя стрессоустойчивости
by looters or worse,
или ещё что-нибудь похуже,
against developing depression or PTSD
от развития депрессии и ПТСР,
from experiencing the stress,
her susceptibility to depression and PTSD,
вероятность развития депрессии и ПТСР,
her home, her family or even her life.
дом, семью, или даже жизнь.
the smallpox vaccine,
положила начало
was widely available.
вакцина от туберкулёза.
sensitive and creative and empathetic.
утончённым, талантливым и чутким.
by constitution and not biology.
в конституции, а не биологии.
today about depression.
можно услышать о депрессии.
opened the door
положило начало
that followed after,
open the possibility of a whole new field:
может положить начало новой области:
choose to do with it.
и действий как общества.
ABOUT THE SPEAKER
Rebecca Brachman - Neuroscientist, writer, entrepreneurRebecca Brachman is a pioneer in the field of preventative psychopharmacology, developing drugs to enhance stress resilience and prevent mental illness.
Why you should listen
Current treatments for mood disorders only suppress symptoms without addressing the underlying disease, and there are no known cures. The drugs Rebecca Brachman is developing would be the first to prevent psychiatric disorders such as post-traumatic stress disorder (PTSD) and depression.
Brachman completed her PhD at Columbia University, prior to which she was a fellow at the National Institutes of Health, where she discovered that immune cells carry a memory of psychological stress and that white blood cells can act as antidepressants and resilience-enhancers. Brachman's research has been featured in The Atlantic, WIRED and Business Insider, and her work was recently described by Dr. George Slavich on NPR as a "moonshot project that is very much needed in the mental health arena."
In addition to conducting ongoing research at Columbia, Brachman is an NYCEDC Entrepreneurship Lab Fellow and cofounder of Paravax -- a biotech startup developing vaccine-like prophylactic drugs ("paravaccines") -- along with her scientific collaborator, Christine Ann Denny. She is also working on a non-profit venture to repurpose existing generic drugs for use as prophylactics, and previously served as the Interim Program Director for Outreach at the Zuckerman Institute at Columbia University.
Brachman is also a playwright and screenwriter. She holds Bachelor's degrees in both neuroscience and creative wWriting, and she is currently working on a tech-focused writing project with her long-time writing partner, Sean Calder ("Grimm," "Damages," "ER"). She served as the director of NeuWrite, a national network of science-writing groups that fosters ongoing collaboration between scientists, writers and artists, and she has been featured as a storyteller at The Story Collider.
(Photo: Kenneth Willardt)
Rebecca Brachman | Speaker | TED.com