David Brenner: A new weapon in the fight against superbugs
David Brenner: Nowa broń w walce z superbakteriami
We are decidedly losing the war against superbugs, and with a projected annual death toll by 2050 of 10 million people. David Brenner would like to stop that. Full bio
Double-click the English transcript below to play the video.
at the moment,
of some soccer fans --
które wam teraz pokazuję.
celebrating a famous victory
cieszących się ze słynnego zwycięstwa
that's my friend Paul Rice.
siedzi mój przyjaciel Paul Rice.
after this picture was taken,
for some minor surgery,
żeby poddać się drobnemu zabiegowi.
a superbug-related infection,
from a couple of TEDsters,
kilku entuzjastów konferencji TED,
personal war on superbugs.
osobistą wojnę.
for a moment.
w latach 40. ubiegłego wieku,
introduction of antibiotics.
antybiotyków na szeroką skalę.
have continued to emerge,
oporne na działanie leków bakterie.
newer and newer drugs
opracowywać coraz to nowsze leki,
actually is the origin of superbugs,
do powstawania superbakterii,
for which we don't have effective drugs.
na które nie ma skutecznego lekarstwa.
at least some of these superbugs.
przynajmniej niektóre z nich.
common ones around today.
bardziej rozpowszechnione.
wywołanych przez superbakterie.
approach to the problem,
na opracowywaniu nowych leków,
by the middle of this century
from superbugs will be 10 million.
przez superbakterie wyniesie 10 milionów.
that's actually more
that died of cancer worldwide last year.
that we're not on a good road,
że zmierzamy w złym kierunku,
to this problem is not working.
nowych leków nie działa.
a physics-based approach --
zastosować innego podejścia
every kind of microbe,
jak zabijać każdy drobnoustrój,
for more than 100 years.
już od ponad 100 lat.
what ultraviolet light is.
that includes infrared,
mieszczącego w sobie podczerwień
of this group is ultraviolet light.
fale krótkiej długości to światło UV.
kluczowe znaczenie ma fakt,
by a completely different mechanism
w zupełnie inny sposób
of killing a drug-resistant bacteria
zabijać bakterie oporne na leki,
is so good at killing all bugs,
tak skuteczne w zabijaniu bakterii,
to sterilize rooms,
do sterylizacji pomieszczeń
ultraviolet light.
bakteriobójczym światłem UV.
in this picture, actually,
is actually a health hazard,
jak na przykład zaćmę.
germicidal, ultraviolet light
bakteriobójczego światła UV,
when there are people around.
to kill all bacteria,
background kicked into this story.
moje doświadczenie z zakresu fizyki.
wavelength of ultraviolet light
rodzaj światła UV o określonej długości,
to daleki ultrafiolet typu C.
of the ultraviolet spectrum.
is the surface of our skin,
some bacteria in the air above the skin.
ultraviolet light impinges on this.
bakteriobójczego światła UV.
is really good at killing bacteria,
into the upper layers of our skin,
those key cells in our skin
can lead to skin cancer.
prowadzić do raka skóry.
dalekiego ultrafioletu typu C.
in the air above them.
perfectly fine at killing bacteria,
skutecznie zabija bakterie,
is penetrate into our skin.
solid physics reason for that:
bo zgodnie z prawami fizyki
absorbed by all biological materials,
absorbowany przez materiały biologiczne.
are really, really, really small,
bardzo, bardzo małe,
penetrate them and kill them,
przeniknąć przez nie i je zabić.
is penetrate into skin,
the dead-cell area
should be able to kill bacteria,
powinien zabijać bakterie,
has been working on
to both these questions
mogę odpowiedzieć twierdząco.
surprised to say that,
of physics at work.
a completely new weapon,
in food preparation areas.
the spread of viruses,
rozprzestrzenianiu się wirusów,
in airports or airplanes,
będzie można wykorzystać na lotniskach,
of viruses like H1N1 virus.
wirusów takich jak H1N1.
przyjaciela, Paula Rice'a.
and well-loved local politician
in the center of Liverpool,
stoi pomnik ku jego pamięci.
in this war against superbugs.
w walce z superbakteriami.
I've got a question for you.
in developing this,
w rozwoju tej technologii jesteś
to trying to roll out
masz jeszcze do pokonania,
that it kills all bacteria,
że ta technologia zabija bakterie,
that before we started,
of tests about safety,
dotyczących bezpieczeństwa.
than it is about efficacy.
a nie skuteczność.
melanoma many years on.
nie wywoła po wielu latach czerniaka.
are pretty well done at this point.
we have to deal with,
z Agencją do spraw Żywności i Leków,
in the real world without FDA approval.
nie moglibyśmy zastosować tej metody.
to launch first in the US,
najpierw w Stanach?
biologists, doctors,
biologów i lekarzy,
there is a certain skepticism
do tego ze sceptycyzmem,
that UV light is not safe.
światło UV nie jest bezpieczne.
we're going to be standing on.
bardzo znacząca praca.
for sharing this with us.
za wystąpienie, Davidzie.
ABOUT THE SPEAKER
David Brenner - Radiation scientistWe are decidedly losing the war against superbugs, and with a projected annual death toll by 2050 of 10 million people. David Brenner would like to stop that.
Why you should listen
David Brenner directs the Center for Radiological Research at Columbia University Medical Center in New York City and has numerous distinctions within his field such as the Oxford University Weldon Prize and the Radiation Research Society Failla Gold Medal Award. Founded by a student of Marie Curie more than a century ago, the Center for Radiological Research is committed to exploiting all forms of radiation to improve medical care.
As Brenner sees it, radiation is very much a two-edged sword -- used in the right way it has revolutionized modern medicine, such as through CT scans and as a cure for many cancers. But radiation used in the wrong way can be harmful. To maximize the benefits of the many different types of radiation, we need to understand exactly how they affect us, from our DNA to the whole person.
Over the past six years, Brenner and his team have applied this idea in working towards a safe way to kill drug-resistant bacteria such as MRSA, as well as airborne microbes such as influenza and TB, using a unique type of ultra-violet light, known as far-UVC.
In short, it is pure physics -- far-UVC light is safe for us because it cannot even penetrate through the dead-cell layer on the surface of our skin or the tear layer on the surface of our eyes. But because bacteria and viruses are physically very small, far-UVC light does have enough penetration to efficiently kill them.
Brenner envisions a wide range of applications for this new weapon in the war against superbugs, such as in operating rooms during surgery to minimize the risk of surgical site infections, in schools to prevent the spread of influenza or measles, in shelters to prevent the spread of TB, or in airplanes and airports to prevent the global spread of viruses like H1N1.
David Brenner | Speaker | TED.com