ABOUT THE SPEAKER
Lee Cronin - Chemist
A professor of chemistry, nanoscience and chemical complexity, Lee Cronin and his research group investigate how chemistry can revolutionize modern technology and even create life.

Why you should listen

Lee Cronin's lab at the University of Glasgow does cutting-edge research into how complex chemical systems, created from non-biological building blocks, can have real-world applications with wide impact. At TEDGlobal 2012, Cronin shared some of the lab's latest work: creating a 3D printer for molecules. This device -- which has been prototyped -- can download plans for molecules and print them, in the same way that a 3D printer creates objects. In the future, Cronin says this technology could potentially be used to print medicine -- cheaply and wherever it is needed. As Cronin says: "What Apple did for music, I'd like to do for the discovery and distribution of prescription drugs."

At TEDGlobal 2011, Cronin shared his lab's bold plan to create life. At the moment, bacteria is the minimum unit of life -- the smallest chemical unit that can undergo evolution. But in Cronin's emerging field, he's thinking about forms of life that won't be biological. To explore this, and to try to understand how life itself originated from chemicals, Cronin and others are attempting to create truly artificial life from completely non-biological chemistries that mimic the behavior of natural cells. They call these chemical cells, or Chells. 

Cronin's research interests also encompass self-assembly and self-growing structures -- the better to assemble life at nanoscale. At the University of Glasgow, this work on crystal structures is producing a raft of papers from his research group. He says: "Basically one of my longstanding research goals is to understand how life emerged on planet Earth and re-create the process."

Read the papers referenced in his TEDGlobal 2102 talk:

Integrated 3D-printed reactionware for chemical synthesis and analysis, Nature Chemistry

Configurable 3D-Printed millifluidic and microfluidic ‘lab on a chip’ reactionware devices, Lab on a Chip

More profile about the speaker
Lee Cronin | Speaker | TED.com
TEDGlobal 2012

Lee Cronin: Print your own medicine

Лий Кронин: Принтирайте собствените си лекарства

Filmed:
1,045,687 views

Химикът Лий Кронин работи над 3Д принтер, който вместо обекти е способен да принтира молекули. Едно много вълнуващо дългосрочно приложение: принтиране на ваши собствени лекарства, използвайки химически мастила.
- Chemist
A professor of chemistry, nanoscience and chemical complexity, Lee Cronin and his research group investigate how chemistry can revolutionize modern technology and even create life. Full bio

Double-click the English transcript below to play the video.

00:16
OrganicОрганични chemistsхимици make moleculesмолекули,
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Органичните химици правят молекули,
00:19
very complicatedсложен moleculesмолекули,
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много сложни молекули,
00:21
by choppingкълцане up a bigголям moleculeмолекула into smallмалък moleculesмолекули
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чрез превръщане на голяма молекула в малки молекули
00:24
and reverseобратен engineeringинженерство.
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и обратен инженеринг.
00:26
And as a chemistхимик,
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И като химик,
00:27
one of the things I wanted to askпитам my researchизследване groupгрупа a coupleдвойка of yearsгодини agoпреди is,
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едно от нещата, които исках да попитам моята изследователска група преди няколко години бе,
00:31
could we make a really coolготино universalуниверсален chemistryхимия setкомплект?
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можем ли да направим наистина готин универсален химически комплект?
00:35
In essenceсъщност, could we "appап" chemistryхимия?
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По същество бихме ли могли да напишем приложения за химията?
00:40
Now what would this mean, and how would we do it?
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Какво би означавало това, и как да го направим?
00:43
Well to startначало to do this,
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За да започнем да правим това,
00:45
we tookвзеха a 3D printerпечатар
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взехме 3D принтер
00:47
and we startedзапочна to printпечат our beakersБехерови чаши and our testтест tubesтръби on one sideстрана
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и започнахме да отпечатваме нашите стъкленици и епруветки от една страна
00:51
and then printпечат the moleculeмолекула at the sameедин и същ time on the other sideстрана
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и след това да отпечатваме молекула в същото време от другата страна
00:55
and combineкомбайн them togetherзаедно in what we call reactionwarereactionware.
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и да ги комбинираме заедно в това, което наричаме реакционенуер.
00:58
And so by printingпечатане the vesselплавателен съд and doing the chemistryхимия at the sameедин и същ time,
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И така чрез отпечатване на съда и правейки химията в същото време,
01:03
we mayможе startначало to accessдостъп this universalуниверсален toolkitинструментариум of chemistryхимия.
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можем да започнем да получаваме достъп до този универсален инструментариум на химията.
01:08
Now what could this mean?
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Сега какво може да означава това?
01:09
Well if we can embedзакрепвам biologicalбиологичен and chemicalхимически networksмрежи like a searchТърсене engineдвигател,
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Ами ако можем да вградим биологични и химически мрежи като търсачка,
01:15
so if you have a cellклетка that's illаз ще that you need to cureлек
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така че, ако имате една клетка, която е болна и трябва да се лекува
01:18
or bacteriaбактерии that you want to killубивам,
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или бактерии, които искате да убиете,
01:20
if you have this embeddedвградени in your deviceприспособление
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ако имате това вградено във вашето устройство
01:22
at the sameедин и същ time, and you do the chemistryхимия,
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в същото време и правите химия,
01:24
you mayможе be ableспособен to make drugsнаркотици in a newнов way.
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може да успеете да направите лекарства по нов начин.
01:28
So how are we doing this in the labлаборатория?
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И така, как правим това в лабораторията?
01:30
Well it requiresизисква softwareсофтуер, it requiresизисква hardwareжелезария
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Ами това изисква софтуер, изисква хардуер
01:33
and it requiresизисква chemicalхимически inksмастила.
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и изисква химически мастила.
01:36
And so the really coolготино bitмалко is,
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И така, наистина готиното нещо е,
01:37
the ideaидея is that we want to have a universalуниверсален setкомплект of inksмастила
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идеята е, че искаме да имаме универсален набор от мастила,
01:40
that we put out with the printerпечатар,
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които да идват с принтера,
01:43
and you downloadИзтегли the blueprintплан, the organicорганичен chemistryхимия for that moleculeмолекула
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и да можете да изтеглите модела, органичната химия за тази молекула
01:47
and you make it in the deviceприспособление.
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и да го направите в устройството.
01:50
And so you can make your moleculeмолекула in the printerпечатар usingизползвайки this softwareсофтуер.
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И така можете да направите вашата молекула в принтера, използвайки този софтуер.
01:55
So what could this mean?
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Така че какво може да означава това?
01:58
Well, ultimatelyв края на краищата, it could mean that you could printпечат your ownсобствен medicineмедицина.
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Е в крайна сметка, може да означава, че можете да отпечатате вашите собствени лекарства.
02:03
And this is what we're doing in the labлаборатория at the momentмомент.
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И това е, което правим в лабораторията в момента.
02:05
But to take babyбебе stepsстъпки to get there,
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Но да направим бебешки стъпки, за да отидем там,
02:06
first of all we want to look at drugлекарство designдизайн and productionпроизводство,
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на първо място искаме да разгледаме проектирането и производството на лекарства,
02:09
or drugлекарство discoveryоткритие and manufacturingпроизводство.
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или откриването и произвеждането им.
02:12
Because if we can manufactureпроизводство it after we'veние имаме discoveredоткрит it,
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Защото ако можем да ги произведем след като ги открием,
02:15
we could deployразполагане на it anywhereнавсякъде.
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можем да ги използваме навсякъде.
02:17
You don't need to go to the chemistхимик anymoreвече.
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Няма да е нужно да ходите до аптеката повече.
02:19
We can printпечат drugsнаркотици at pointточка of need.
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Ще можем да отпечатваме лекарства в момент на нужда.
02:22
We can downloadИзтегли newнов diagnosticsдиагностика.
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Ще можем да сваляме нови методи за диагностика.
02:24
Say a newнов superсупер bugбуболечка has emergedвъзникна.
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Да речем че се появи нов супер бъг.
02:26
You put it in your searchТърсене engineдвигател,
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Можете да го сложите в търсачката си,
02:28
and you createсъздавам the drugлекарство to treatлечение the threatзаплаха.
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и да създадате лекарството за лечение срещу заплахата.
02:31
So this allowsпозволява you on-the-flyна-определителен член-муха molecularмолекулен assemblyмонтаж.
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Така това ви позволява скоростно молекулярно асемблиране.
02:35
But perhapsможе би for me the coreсърцевина bitмалко going into the futureбъдеще
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Но може би най-значимото за мен за в бъдеще
02:38
is this ideaидея of takingприемате your ownсобствен stemстебло cellsклетки,
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е тази идея за вземане на вашите собствени стволови клетки,
02:41
with your genesгени and your environmentзаобикаляща среда,
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с гените и околната среда,
02:43
and you printпечат your ownсобствен personalперсонален medicineмедицина.
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и отпечатване на вашите собствени лични лекарства.
02:46
And if that doesn't seemИзглежда fancifulнереален enoughдостатъчно,
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И ако това не изглежда достатъчно нереално,
02:48
where do you think we're going to go?
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къде мислите, че ще отидем?
02:50
Well, you're going to have your ownсобствен personalперсонален matterвъпрос fabricatorfabricator.
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Ами ще имате свой собствен личен създател на материя.
02:55
BeamГреда me up, ScottyСкоти.
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Телепортирай ме, Скоти.
02:57
(ApplauseАплодисменти)
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(Аплодисменти)
Translated by Darina Stoyanova
Reviewed by Anton Hikov

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ABOUT THE SPEAKER
Lee Cronin - Chemist
A professor of chemistry, nanoscience and chemical complexity, Lee Cronin and his research group investigate how chemistry can revolutionize modern technology and even create life.

Why you should listen

Lee Cronin's lab at the University of Glasgow does cutting-edge research into how complex chemical systems, created from non-biological building blocks, can have real-world applications with wide impact. At TEDGlobal 2012, Cronin shared some of the lab's latest work: creating a 3D printer for molecules. This device -- which has been prototyped -- can download plans for molecules and print them, in the same way that a 3D printer creates objects. In the future, Cronin says this technology could potentially be used to print medicine -- cheaply and wherever it is needed. As Cronin says: "What Apple did for music, I'd like to do for the discovery and distribution of prescription drugs."

At TEDGlobal 2011, Cronin shared his lab's bold plan to create life. At the moment, bacteria is the minimum unit of life -- the smallest chemical unit that can undergo evolution. But in Cronin's emerging field, he's thinking about forms of life that won't be biological. To explore this, and to try to understand how life itself originated from chemicals, Cronin and others are attempting to create truly artificial life from completely non-biological chemistries that mimic the behavior of natural cells. They call these chemical cells, or Chells. 

Cronin's research interests also encompass self-assembly and self-growing structures -- the better to assemble life at nanoscale. At the University of Glasgow, this work on crystal structures is producing a raft of papers from his research group. He says: "Basically one of my longstanding research goals is to understand how life emerged on planet Earth and re-create the process."

Read the papers referenced in his TEDGlobal 2102 talk:

Integrated 3D-printed reactionware for chemical synthesis and analysis, Nature Chemistry

Configurable 3D-Printed millifluidic and microfluidic ‘lab on a chip’ reactionware devices, Lab on a Chip

More profile about the speaker
Lee Cronin | Speaker | TED.com

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