ABOUT THE SPEAKER
Lee Cronin - Chemist
A professor of chemistry, nanoscience and chemical complexity, Lee Cronin and his research group investigate how chemistry can revolutionize modern technology and even create life.

Why you should listen

Lee Cronin's lab at the University of Glasgow does cutting-edge research into how complex chemical systems, created from non-biological building blocks, can have real-world applications with wide impact. At TEDGlobal 2012, Cronin shared some of the lab's latest work: creating a 3D printer for molecules. This device -- which has been prototyped -- can download plans for molecules and print them, in the same way that a 3D printer creates objects. In the future, Cronin says this technology could potentially be used to print medicine -- cheaply and wherever it is needed. As Cronin says: "What Apple did for music, I'd like to do for the discovery and distribution of prescription drugs."

At TEDGlobal 2011, Cronin shared his lab's bold plan to create life. At the moment, bacteria is the minimum unit of life -- the smallest chemical unit that can undergo evolution. But in Cronin's emerging field, he's thinking about forms of life that won't be biological. To explore this, and to try to understand how life itself originated from chemicals, Cronin and others are attempting to create truly artificial life from completely non-biological chemistries that mimic the behavior of natural cells. They call these chemical cells, or Chells. 

Cronin's research interests also encompass self-assembly and self-growing structures -- the better to assemble life at nanoscale. At the University of Glasgow, this work on crystal structures is producing a raft of papers from his research group. He says: "Basically one of my longstanding research goals is to understand how life emerged on planet Earth and re-create the process."

Read the papers referenced in his TEDGlobal 2102 talk:

Integrated 3D-printed reactionware for chemical synthesis and analysis, Nature Chemistry

Configurable 3D-Printed millifluidic and microfluidic ‘lab on a chip’ reactionware devices, Lab on a Chip

More profile about the speaker
Lee Cronin | Speaker | TED.com
TEDGlobal 2012

Lee Cronin: Print your own medicine

李 克罗宁:打印你自己的药物

Filmed:
1,045,687 views

化学家李.克罗宁在研究一种能打印分子的3D打印机。一个令人兴奋且很有潜力的长期应用程式:利用化学链接来打印你自己的药物。
- Chemist
A professor of chemistry, nanoscience and chemical complexity, Lee Cronin and his research group investigate how chemistry can revolutionize modern technology and even create life. Full bio

Double-click the English transcript below to play the video.

00:16
Organic有机 chemists化学家 make molecules分子,
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有机化学家制作分子,
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very complicated复杂 molecules分子,
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非常复杂的分子,
00:21
by chopping斩波 up a big molecule分子 into small molecules分子
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把大的分子割成小的
00:24
and reverse相反 engineering工程.
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再反过来。
00:26
And as a chemist化学家,
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作为一名化学家,
00:27
one of the things I wanted to ask my research研究 group a couple一对 of years年份 ago is,
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我几年前便问我的研究小组,
00:31
could we make a really cool universal普遍 chemistry化学 set?
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我们可能做出很酷的通用化学设置吗?
00:35
In essence本质, could we "app应用" chemistry化学?
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本质上讲,我们可以把化学软件化吗?
00:40
Now what would this mean, and how would we do it?
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这意味什么,我们又可以怎么做?
00:43
Well to start开始 to do this,
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这样开始吧,
00:45
we took a 3D printer打印机
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我们用一台3D打印机
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and we started开始 to print打印 our beakers烧杯 and our test测试 tubes on one side
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开始把我们烧杯和试管打印在一面
00:51
and then print打印 the molecule分子 at the same相同 time on the other side
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然后在另一面同时打印上分子
00:55
and combine结合 them together一起 in what we call reactionwarereactionware.
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然后将两者在我们称之为感应件的仪器当中合并。
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And so by printing印花 the vessel船只 and doing the chemistry化学 at the same相同 time,
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打印容器的同时,进性化学过程
01:03
we may可能 start开始 to access访问 this universal普遍 toolkit工具包 of chemistry化学.
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我们可能会开始接近这个通用的化学工具箱。
01:08
Now what could this mean?
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这又意味什么?
01:09
Well if we can embed biological生物 and chemical化学 networks网络 like a search搜索 engine发动机,
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如果我们可把生物和化学网络做成像搜索引擎一样,
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so if you have a cell细胞 that's ill生病 that you need to cure治愈
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当您有哪个细胞生病了,需要治愈
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or bacteria that you want to kill,
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或你想杀菌,
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if you have this embedded嵌入式 in your device设备
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若您将这组件嵌在您的设备里
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at the same相同 time, and you do the chemistry化学,
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同时,你进行化学过程
01:24
you may可能 be able能够 to make drugs毒品 in a new way.
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您便可以用新方法做出药品。
01:28
So how are we doing this in the lab实验室?
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那么,我们如何在实验室中做这个呢?
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Well it requires要求 software软件, it requires要求 hardware硬件
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它需要软件和硬件
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and it requires要求 chemical化学 inks油墨.
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它也需要化学油墨。
01:36
And so the really cool bit is,
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最酷的一点是,
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the idea理念 is that we want to have a universal普遍 set of inks油墨
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我们想要一套通用的油墨
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that we put out with the printer打印机,
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可以和打印机一同推出
01:43
and you download下载 the blueprint蓝图, the organic有机 chemistry化学 for that molecule分子
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您下载蓝图,您需要的分子的有机化学过程
01:47
and you make it in the device设备.
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在该设备里做。
01:50
And so you can make your molecule分子 in the printer打印机 using运用 this software软件.
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因此,你可以用这套软件造你的分子。
01:55
So what could this mean?
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这意味什么?
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Well, ultimately最终, it could mean that you could print打印 your own拥有 medicine医学.
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最终,这意味您可以打印你自己的药。
02:03
And this is what we're doing in the lab实验室 at the moment时刻.
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而这是我们目前在实验室里所做。
02:05
But to take baby宝宝 steps脚步 to get there,
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但是,要一步步的达到那里,
02:06
first of all we want to look at drug药物 design设计 and production生产,
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首先,我们在看药物的设计和产品,
02:09
or drug药物 discovery发现 and manufacturing制造业.
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或药物的发现和制造。
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Because if we can manufacture制造 it after we've我们已经 discovered发现 it,
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因为如果我们能找到它,制造它,
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we could deploy部署 it anywhere随地.
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我们便可以任何地方调配它。
02:17
You don't need to go to the chemist化学家 anymore.
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您再也不需要去找化学家。
02:19
We can print打印 drugs毒品 at point of need.
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我们可以打印需要的药品。
02:22
We can download下载 new diagnostics诊断.
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我们可以下载新的诊断方法。
02:24
Say a new super bug窃听器 has emerged出现.
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那么说,一个新的超级"bug"已经出现。
02:26
You put it in your search搜索 engine发动机,
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把它放到你的搜索引擎,
02:28
and you create创建 the drug药物 to treat对待 the threat威胁.
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您就可以创建药物来治疗病痛。
02:31
So this allows允许 you on-the-fly在即时 molecular分子 assembly部件.
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这允许您随时进行分子组装。
02:35
But perhaps也许 for me the core核心 bit going into the future未来
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但,对我来说,未来最核心的部分
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is this idea理念 of taking服用 your own拥有 stem cells细胞,
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是照你自己的干细胞,
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with your genes基因 and your environment环境,
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结合你的基因和环境,
02:43
and you print打印 your own拥有 personal个人 medicine医学.
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来打印你自己须要的药。
02:46
And if that doesn't seem似乎 fanciful撒娇的 enough足够,
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如果这看起来还不够科幻的话,
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where do you think we're going to go?
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你觉得我们该往哪方向去?
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Well, you're going to have your own拥有 personal个人 matter fabricator制造者.
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嗯,你也要有自己的计划喔。
02:55
Beam光束 me up, Scotty.
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把我传上飞船。(电视剧"Star Trek"的标志性台词)
02:57
(Applause掌声)
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(掌声)
Translated by Xue Chen
Reviewed by Sharon Loh

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ABOUT THE SPEAKER
Lee Cronin - Chemist
A professor of chemistry, nanoscience and chemical complexity, Lee Cronin and his research group investigate how chemistry can revolutionize modern technology and even create life.

Why you should listen

Lee Cronin's lab at the University of Glasgow does cutting-edge research into how complex chemical systems, created from non-biological building blocks, can have real-world applications with wide impact. At TEDGlobal 2012, Cronin shared some of the lab's latest work: creating a 3D printer for molecules. This device -- which has been prototyped -- can download plans for molecules and print them, in the same way that a 3D printer creates objects. In the future, Cronin says this technology could potentially be used to print medicine -- cheaply and wherever it is needed. As Cronin says: "What Apple did for music, I'd like to do for the discovery and distribution of prescription drugs."

At TEDGlobal 2011, Cronin shared his lab's bold plan to create life. At the moment, bacteria is the minimum unit of life -- the smallest chemical unit that can undergo evolution. But in Cronin's emerging field, he's thinking about forms of life that won't be biological. To explore this, and to try to understand how life itself originated from chemicals, Cronin and others are attempting to create truly artificial life from completely non-biological chemistries that mimic the behavior of natural cells. They call these chemical cells, or Chells. 

Cronin's research interests also encompass self-assembly and self-growing structures -- the better to assemble life at nanoscale. At the University of Glasgow, this work on crystal structures is producing a raft of papers from his research group. He says: "Basically one of my longstanding research goals is to understand how life emerged on planet Earth and re-create the process."

Read the papers referenced in his TEDGlobal 2102 talk:

Integrated 3D-printed reactionware for chemical synthesis and analysis, Nature Chemistry

Configurable 3D-Printed millifluidic and microfluidic ‘lab on a chip’ reactionware devices, Lab on a Chip

More profile about the speaker
Lee Cronin | Speaker | TED.com