ABOUT THE SPEAKER
Lee Cronin - Chemist
A professor of chemistry, nanoscience and chemical complexity, Lee Cronin and his research group investigate how chemistry can revolutionize modern technology and even create life.

Why you should listen

Lee Cronin's lab at the University of Glasgow does cutting-edge research into how complex chemical systems, created from non-biological building blocks, can have real-world applications with wide impact. At TEDGlobal 2012, Cronin shared some of the lab's latest work: creating a 3D printer for molecules. This device -- which has been prototyped -- can download plans for molecules and print them, in the same way that a 3D printer creates objects. In the future, Cronin says this technology could potentially be used to print medicine -- cheaply and wherever it is needed. As Cronin says: "What Apple did for music, I'd like to do for the discovery and distribution of prescription drugs."

At TEDGlobal 2011, Cronin shared his lab's bold plan to create life. At the moment, bacteria is the minimum unit of life -- the smallest chemical unit that can undergo evolution. But in Cronin's emerging field, he's thinking about forms of life that won't be biological. To explore this, and to try to understand how life itself originated from chemicals, Cronin and others are attempting to create truly artificial life from completely non-biological chemistries that mimic the behavior of natural cells. They call these chemical cells, or Chells. 

Cronin's research interests also encompass self-assembly and self-growing structures -- the better to assemble life at nanoscale. At the University of Glasgow, this work on crystal structures is producing a raft of papers from his research group. He says: "Basically one of my longstanding research goals is to understand how life emerged on planet Earth and re-create the process."

Read the papers referenced in his TEDGlobal 2102 talk:

Integrated 3D-printed reactionware for chemical synthesis and analysis, Nature Chemistry

Configurable 3D-Printed millifluidic and microfluidic ‘lab on a chip’ reactionware devices, Lab on a Chip

More profile about the speaker
Lee Cronin | Speaker | TED.com
TEDGlobal 2012

Lee Cronin: Print your own medicine

Lee Cronin: Ispišite svoj vlastiti lijek

Filmed:
1,045,687 views

Kemičar Lee Cronin radi na 3D pisaču koji umjesto predmeta može ispisivati molekule. Uzbudljiva potencijalna dugoročna primjena: ispis vlastitih lijekova korištenjem kemijskih tinta.
- Chemist
A professor of chemistry, nanoscience and chemical complexity, Lee Cronin and his research group investigate how chemistry can revolutionize modern technology and even create life. Full bio

Double-click the English transcript below to play the video.

00:16
OrganicOrganski chemistskemičari make moleculesmolekule,
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Organski kemičari prave molekule,
00:19
very complicatedsložen moleculesmolekule,
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vrlo komplicirane molekule,
00:21
by choppingcijepanje up a bigvelika moleculemolekula into smallmali moleculesmolekule
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tako što cijepaju velike molekule u manje
00:24
and reversepreokrenuti engineeringinženjering.
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i zatim primjenjuju obrnuti inženjering
00:26
And as a chemistkemičar,
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Kao kemičar,
00:27
one of the things I wanted to askpitati my researchistraživanje groupskupina a couplepar of yearsgodina agoprije is,
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prije nekoliko sam godina htio
pitati svoju istraživačku skupinu
00:31
could we make a really coolsvjež universaluniverzalan chemistrykemija setset?
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možemo li napraviti jedan
cool univerzalni set za kemiju?
00:35
In essencesuština, could we "appapp" chemistrykemija?
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U biti, možemo li kemiju učiniti aplikacijom?
00:40
Now what would this mean, and how would we do it?
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Što bi to značilo i kako bismo to učinili?
00:43
Well to startpočetak to do this,
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Kako bismo započeli s time,
00:45
we tookuzeo a 3D printerprinter
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uzeli smo 3D pisač
00:47
and we startedpočeo to printotisak our beakersčaše and our testtest tubescijevi on one sidestrana
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i počeli ispisivati čaše i epruvete s jedne strane,
00:51
and then printotisak the moleculemolekula at the sameisti time on the other sidestrana
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a molekule istovremeno s druge strane.
00:55
and combinekombinirati them togetherzajedno in what we call reactionwarereactionware.
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Kombinirali smo ih kako bismo
dobili tzv. "reactionware."
00:58
And so by printingtiskanje the vesselBrod and doing the chemistrykemija at the sameisti time,
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Ispisivanje posude i istovremeno
obavljanje kemijskih radnji
01:03
we maysvibanj startpočetak to accesspristup this universaluniverzalan toolkitalat of chemistrykemija.
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moglo bi biti prvi korak prema
tom univerzalnom setu za kemiju.
01:08
Now what could this mean?
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Što bi to moglo značiti?
01:09
Well if we can embedugraditi biologicalbiološki and chemicalkemijski networksmreže like a searchtraži enginemotor,
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Kad bismo mogli ugraditi biološke
i kemijske mreže poput pretraživača,
01:15
so if you have a cellćelija that's illbolestan that you need to curelijek
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tako da, ako imate stanicu
koja je bolesna i koju trebate liječiti,
01:18
or bacteriabakterija that you want to killubiti,
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ili imate bakteriju koju želite ubiti,
01:20
if you have this embeddedugrađen in your deviceuređaj
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ako to imate ugrađeno u svoj uređaj u isto vrijeme,
01:22
at the sameisti time, and you do the chemistrykemija,
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i obavite kemijske radnje,
01:24
you maysvibanj be ableu stanju to make drugslijekovi in a newnovi way.
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mogli biste izraditi lijekove na nov način.
01:28
So how are we doing this in the lablaboratorija?
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Kako mi to činimo u laboratoriju?
01:30
Well it requirestraži softwaresoftver, it requirestraži hardwarehardver
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Za to je potreban softver, kao i hardver.
01:33
and it requirestraži chemicalkemijski inkstinte.
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Potrebne su i kemijske tinte.
01:36
And so the really coolsvjež bitbit is,
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A najzanimljivija je ideja
01:37
the ideaideja is that we want to have a universaluniverzalan setset of inkstinte
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da želimo imati univerzalan set tinta
01:40
that we put out with the printerprinter,
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koje ćemo dati s pisačem,
01:43
and you downloadpreuzimanje datoteka the blueprintnacrt, the organicorganski chemistrykemija for that moleculemolekula
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vi učitate nacrt, organsku kemiju za tu molekulu
01:47
and you make it in the deviceuređaj.
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i napravite je u uređaju.
01:50
And so you can make your moleculemolekula in the printerprinter usingkoristeći this softwaresoftver.
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Tako možete svoju molekulu možete načiniti
u pisaču, koristeći ovaj softver.
01:55
So what could this mean?
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Što bi to moglo značiti?
01:58
Well, ultimatelyna kraju, it could mean that you could printotisak your ownvlastiti medicinelijek.
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U konačnici, moglo bi značiti da biste
mogli ispisivati sami svoje lijekove.
02:03
And this is what we're doing in the lablaboratorija at the momenttrenutak.
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To upravo činimo u laboratoriju.
02:05
But to take babydijete stepskoraci to get there,
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Ali kako bismo činili male korake prema tome cilju,
02:06
first of all we want to look at drugdroga designdizajn and productionproizvodnja,
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prvo želimo vidjeti oblikovanje i proizvodnju lijeka,
02:09
or drugdroga discoveryotkriće and manufacturingproizvodnja.
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ili otkrivanje i izradu.
02:12
Because if we can manufactureproizvodnja it after we'veimamo discoveredotkriven it,
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Ako ih možemo proizvesti nakon što smo ih otkrili,
02:15
we could deployuvođenje it anywherebilo kuda.
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možemo ih poslati bilo kamo.
02:17
You don't need to go to the chemistkemičar anymoreviše.
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Ne morate više ići u ljekarnu.
02:19
We can printotisak drugslijekovi at pointtočka of need.
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Možemo ispisivati lijekove prema potrebi.
02:22
We can downloadpreuzimanje datoteka newnovi diagnosticsdijagnostika.
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Možemo učitavati nove dijagnostike.
02:24
Say a newnovi supersuper bugbuba has emergedpojavila.
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Recimo da se pojavi nov uzročnik bolesti.
02:26
You put it in your searchtraži enginemotor,
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Stavite ga u svoj pretraživač
02:28
and you createstvoriti the drugdroga to treatliječiti the threatprijetnja.
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i napravite lijek koji će riješiti taj problem.
02:31
So this allowsomogućuje you on-the-flyna--muha molecularmolekularna assemblyskupština.
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To vam omogućava trenutno sastavljanje molekula.
02:35
But perhapsmožda for me the coresrž bitbit going into the futurebudućnost
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Ali za mene je bit koju ćemo razraditi u budućnosti
02:38
is this ideaideja of takinguzimanje your ownvlastiti stemstabljika cellsStanice,
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ideja uzimanja vlastitih matičnih stanica,
02:41
with your genesgeni and your environmentokolina,
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s vlastitim genima i okolinom,
02:43
and you printotisak your ownvlastiti personalosobni medicinelijek.
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i ispisivanje vlastitih personaliziranih lijekova.
02:46
And if that doesn't seemčiniti se fancifulnestvaran enoughdovoljno,
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Ako se to ne čini dovoljno nestvarno,
02:48
where do you think we're going to go?
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što mislite, što ćemo sljedeće učiniti?
02:50
Well, you're going to have your ownvlastiti personalosobni matterstvar fabricatorFabricator.
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Imat ćemo svoj osobni proizvođač tvari.
02:55
BeamZraka me up, ScottyScotty.
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Teleportiraj me, Scotty.
02:57
(ApplausePljesak)
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(Pljesak)
Translated by Senzos Osijek
Reviewed by Katarina Smetko

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ABOUT THE SPEAKER
Lee Cronin - Chemist
A professor of chemistry, nanoscience and chemical complexity, Lee Cronin and his research group investigate how chemistry can revolutionize modern technology and even create life.

Why you should listen

Lee Cronin's lab at the University of Glasgow does cutting-edge research into how complex chemical systems, created from non-biological building blocks, can have real-world applications with wide impact. At TEDGlobal 2012, Cronin shared some of the lab's latest work: creating a 3D printer for molecules. This device -- which has been prototyped -- can download plans for molecules and print them, in the same way that a 3D printer creates objects. In the future, Cronin says this technology could potentially be used to print medicine -- cheaply and wherever it is needed. As Cronin says: "What Apple did for music, I'd like to do for the discovery and distribution of prescription drugs."

At TEDGlobal 2011, Cronin shared his lab's bold plan to create life. At the moment, bacteria is the minimum unit of life -- the smallest chemical unit that can undergo evolution. But in Cronin's emerging field, he's thinking about forms of life that won't be biological. To explore this, and to try to understand how life itself originated from chemicals, Cronin and others are attempting to create truly artificial life from completely non-biological chemistries that mimic the behavior of natural cells. They call these chemical cells, or Chells. 

Cronin's research interests also encompass self-assembly and self-growing structures -- the better to assemble life at nanoscale. At the University of Glasgow, this work on crystal structures is producing a raft of papers from his research group. He says: "Basically one of my longstanding research goals is to understand how life emerged on planet Earth and re-create the process."

Read the papers referenced in his TEDGlobal 2102 talk:

Integrated 3D-printed reactionware for chemical synthesis and analysis, Nature Chemistry

Configurable 3D-Printed millifluidic and microfluidic ‘lab on a chip’ reactionware devices, Lab on a Chip

More profile about the speaker
Lee Cronin | Speaker | TED.com