ABOUT THE SPEAKER
Lee Cronin - Chemist
A professor of chemistry, nanoscience and chemical complexity, Lee Cronin and his research group investigate how chemistry can revolutionize modern technology and even create life.

Why you should listen

Lee Cronin's lab at the University of Glasgow does cutting-edge research into how complex chemical systems, created from non-biological building blocks, can have real-world applications with wide impact. At TEDGlobal 2012, Cronin shared some of the lab's latest work: creating a 3D printer for molecules. This device -- which has been prototyped -- can download plans for molecules and print them, in the same way that a 3D printer creates objects. In the future, Cronin says this technology could potentially be used to print medicine -- cheaply and wherever it is needed. As Cronin says: "What Apple did for music, I'd like to do for the discovery and distribution of prescription drugs."

At TEDGlobal 2011, Cronin shared his lab's bold plan to create life. At the moment, bacteria is the minimum unit of life -- the smallest chemical unit that can undergo evolution. But in Cronin's emerging field, he's thinking about forms of life that won't be biological. To explore this, and to try to understand how life itself originated from chemicals, Cronin and others are attempting to create truly artificial life from completely non-biological chemistries that mimic the behavior of natural cells. They call these chemical cells, or Chells. 

Cronin's research interests also encompass self-assembly and self-growing structures -- the better to assemble life at nanoscale. At the University of Glasgow, this work on crystal structures is producing a raft of papers from his research group. He says: "Basically one of my longstanding research goals is to understand how life emerged on planet Earth and re-create the process."

Read the papers referenced in his TEDGlobal 2102 talk:

Integrated 3D-printed reactionware for chemical synthesis and analysis, Nature Chemistry

Configurable 3D-Printed millifluidic and microfluidic ‘lab on a chip’ reactionware devices, Lab on a Chip

More profile about the speaker
Lee Cronin | Speaker | TED.com
TEDGlobal 2012

Lee Cronin: Print your own medicine

Ли Кронин: Испринтајте си го лекот

Filmed:
1,045,687 views

Хемичарот Ли Кронин работи на создавањето на 3D принтер кој, наместо предмети, може да принта молекули. Ова е возбудлива и потенцијално долготрајна апликација: принтање на сопствените лекови преку користење на хемиски бои.
- Chemist
A professor of chemistry, nanoscience and chemical complexity, Lee Cronin and his research group investigate how chemistry can revolutionize modern technology and even create life. Full bio

Double-click the English transcript below to play the video.

00:16
Organic chemists make molecules,
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Органските хемичари прават молекули,
00:19
very complicated molecules,
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многу сложени молекули,
00:21
by chopping up a big molecule into small molecules
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така што ја разградуваат големата молекула во повеќе мали
00:24
and reverse engineering.
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и потоа користат обратен инженеринг.
00:26
And as a chemist,
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А како хемичар,
00:27
one of the things I wanted to ask my research group a couple of years ago is,
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пред неколку години ја запрашав мојата истражувачка група,
00:31
could we make a really cool universal chemistry set?
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би можеле ли да направиме еден универзален хемиски сет кој ќе биде навистина кул?
00:35
In essence, could we "app" chemistry?
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Во основа, би можеле ли од хемијата да направиме апликација?
00:40
Now what would this mean, and how would we do it?
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Е сега, што значи ова, и како да дојдеме до тоа?
00:43
Well to start to do this,
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За почеток,
00:45
we took a 3D printer
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зедовме еден 3D принтер
00:47
and we started to print our beakers and our test tubes on one side
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и почнавме да ги принтаме лабораториските садови и епруветите од едната страна,
00:51
and then print the molecule at the same time on the other side
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а истовремено, од другата страна ги принтавме молекулите.
00:55
and combine them together in what we call reactionware.
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Потоа ги комбиниравме во нешто што го нарекуваме "риекшнвер."
00:58
And so by printing the vessel and doing the chemistry at the same time,
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И така, принтајќи го садот и работејќи на хемијата истовремено,
01:03
we may start to access this universal toolkit of chemistry.
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пополека ги добиваме универзалните хемиски алатки.
01:08
Now what could this mean?
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Е сега, што би можело да значи ова?
01:09
Well if we can embed biological and chemical networks like a search engine,
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Доколку ги вградиме биолошките и хемиските мрежи по урнек на пребарувачите,
01:15
so if you have a cell that's ill that you need to cure
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па така, ако имате клетка која е болна што треба да ја излечите,
01:18
or bacteria that you want to kill,
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или бактерија што сакате да ја убиете,
01:20
if you have this embedded in your device
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ако овие мрежи ги вградите во вашиот уред,
01:22
at the same time, and you do the chemistry,
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истовремено, и ја направите хемијата,
01:24
you may be able to make drugs in a new way.
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тогаш би можеле да ги произведете лековите, на еден нов начин.
01:28
So how are we doing this in the lab?
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Како го правиме тоа во лабораторијата?
01:30
Well it requires software, it requires hardware
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За ова е потребен софтвер, но и хардвер.
01:33
and it requires chemical inks.
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Потребни се, и хемиски бои.
01:36
And so the really cool bit is,
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А најинтересна е идејата
01:37
the idea is that we want to have a universal set of inks
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дека сакаме да имаме универзален сет на бои
01:40
that we put out with the printer,
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кои ќе одат во пакет со принтерот,
01:43
and you download the blueprint, the organic chemistry for that molecule
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вие само го даунлодирате отпечатокот, органската хемија за молекулата
01:47
and you make it in the device.
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и си ја произведувате во уредот.
01:50
And so you can make your molecule in the printer using this software.
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Така во принтерот можете да си направите сопствена молекула, користејќи го овој софтвер.
01:55
So what could this mean?
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Што би можело ова да значи?
01:58
Well, ultimately, it could mean that you could print your own medicine.
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Во суштина, значи дека би можеле сами да си ги принтате лековите.
02:03
And this is what we're doing in the lab at the moment.
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Токму тоа го правиме во лабораторијата.
02:05
But to take baby steps to get there,
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Но за да дојдеме до таму,
02:06
first of all we want to look at drug design and production,
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пред сè треба да го создадеме и да се позанимаваме
02:09
or drug discovery and manufacturing.
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со производството на лекот.
02:12
Because if we can manufacture it after we've discovered it,
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Ако можеме да го произведуваме, откако веќе сме го создале,
02:15
we could deploy it anywhere.
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тогаш можеме да го распространиме насекаде.
02:17
You don't need to go to the chemist anymore.
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Оттука па натаму веќе не ви треба хемичарот.
02:19
We can print drugs at point of need.
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Можеме да ги принтаме лековите по потреба.
02:22
We can download new diagnostics.
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Можеме да даунлодираме нови дијагностички програми.
02:24
Say a new super bug has emerged.
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Да речеме дека се појавило некое вирусиште.
02:26
You put it in your search engine,
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Го внесувате во вашиот пребарувач,
02:28
and you create the drug to treat the threat.
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и си го правите лекот кој ќе се бори против вирусот.
02:31
So this allows you on-the-fly molecular assembly.
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Ова ви овозможува моментално склопување на молекулите.
02:35
But perhaps for me the core bit going into the future
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Но за мене најважна е оваа идеја, дека во иднината
02:38
is this idea of taking your own stem cells,
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ќе можете да си ги земете вашите матични клетки,
02:41
with your genes and your environment,
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заедно со вашите гени и вашата средина,
02:43
and you print your own personal medicine.
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и ќе можете да си испринтате свој персонализиран лек.
02:46
And if that doesn't seem fanciful enough,
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И ако ова не ви е доволно фантастично,
02:48
where do you think we're going to go?
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што мислите до каде ќе одиме?
02:50
Well, you're going to have your own personal matter fabricator.
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Епа, ќе си имате и личен произведувач на материја т.е. супстанца.
02:55
Beam me up, Scotty.
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Телепортирај ме, Скоти.
02:57
(Applause)
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(Аплауз)
Translated by ALEKSANDAR MITEVSKI
Reviewed by Charlie Psy

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ABOUT THE SPEAKER
Lee Cronin - Chemist
A professor of chemistry, nanoscience and chemical complexity, Lee Cronin and his research group investigate how chemistry can revolutionize modern technology and even create life.

Why you should listen

Lee Cronin's lab at the University of Glasgow does cutting-edge research into how complex chemical systems, created from non-biological building blocks, can have real-world applications with wide impact. At TEDGlobal 2012, Cronin shared some of the lab's latest work: creating a 3D printer for molecules. This device -- which has been prototyped -- can download plans for molecules and print them, in the same way that a 3D printer creates objects. In the future, Cronin says this technology could potentially be used to print medicine -- cheaply and wherever it is needed. As Cronin says: "What Apple did for music, I'd like to do for the discovery and distribution of prescription drugs."

At TEDGlobal 2011, Cronin shared his lab's bold plan to create life. At the moment, bacteria is the minimum unit of life -- the smallest chemical unit that can undergo evolution. But in Cronin's emerging field, he's thinking about forms of life that won't be biological. To explore this, and to try to understand how life itself originated from chemicals, Cronin and others are attempting to create truly artificial life from completely non-biological chemistries that mimic the behavior of natural cells. They call these chemical cells, or Chells. 

Cronin's research interests also encompass self-assembly and self-growing structures -- the better to assemble life at nanoscale. At the University of Glasgow, this work on crystal structures is producing a raft of papers from his research group. He says: "Basically one of my longstanding research goals is to understand how life emerged on planet Earth and re-create the process."

Read the papers referenced in his TEDGlobal 2102 talk:

Integrated 3D-printed reactionware for chemical synthesis and analysis, Nature Chemistry

Configurable 3D-Printed millifluidic and microfluidic ‘lab on a chip’ reactionware devices, Lab on a Chip

More profile about the speaker
Lee Cronin | Speaker | TED.com

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