Juan Enriquez: What will humans look like in 100 years?
胡安.安立奎: 100 年後,人類會變成什麽樣子?
Juan Enriquez thinks and writes about the profound changes that genomics and other life sciences will bring in business, technology, politics and society. Full bio
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the tools together to evolve ourselves.
來改造自己的身體。
and we can evolve plants
我們可以改造植物,
where we really have to ask,
而這是否符合道德?
and do we want to evolve human beings?
in the context of prosthetics,
來談這個話題,
in one of these battles.
失去了一隻手臂,
他製作了一套鎧甲,
of ruling with an iron fist comes from.
have been getting more and more useful,
and as you're thinking about that,
而當你正在這麼想時,
absolutely extraordinary prosthetics.
will go out and say,
可以在出門前說:
do I want to climb?
「這次我想攀登哪一種峭壁呢?」
or does somebody want to ballroom dance?
「有人想穿上義肢跳國標舞嗎?」
is they've been coming inside the body.
義肢已經進入人體內了。
have now become artificial knees.
現在成為人工關節,
about a heart pacemaker as a prosthetic,
「心律調節器是義肢的一種,」
that isn't just, "I'm missing my leg,"
「我少了一條腿 」那樣,
becomes a symbiotic relationship
that I've ever met --
有四個人──
喬伊.雅各布森、鮑伯.蘭--
Joe Jacobson, Bob Lander --
for Extreme Bionics.
「極致仿生研究中心」。
of what you're seeing here is
一件有趣的事情:
now get integrated into the bone.
about how to connect the brain
fundamental aspects of humanity.
改變人類的基本構造了。
depends on the diameter of a nerve.
取決於神經的直徑,
that are external or prosthetic,
theoretically to the point where,
提升反應速度,
you could step out of the way of a bullet.
就可以躲開子彈。
of changes you're talking about.
級數的改變了。
sort of level of prosthetics.
why these are so interesting
from where prosthetics are something
that somebody who is "normal"
which is really interesting,
真的很有趣。
going on over there.
你可以聽到白噪音。
You can have white noise.
順便一提,它們還有手機的功能。
they also put a phone into this.
and also as your phone.
也是你的手機。
want to have a prosthetic voluntarily.
會自願去裝義肢了。
of loosely connected little pieces
看似不相關的小零件,
over the next century or two?
我們想如何改造人類?
to a great philosopher
我們向一位偉大的哲學家求助,
despite being a Yankee fan.
雖然是個洋基球迷。
that it's very tough to make predictions,
預測不是一件簡單的事情,
about the future to begin with,
with people like Tony Atala,
托尼.阿塔拉身上的事,
isn't having something external, titanium.
金屬鈦這種外來的材料。
is take your own gene code,
than any kind of a prosthetic.
the work of Craig Venter and Ham Smith.
和翰姆.史密斯的作品。
that we've been doing
how to reprogram cells.
in those organs.
the cells in those organs,
器官內的細胞,
more radiation-resistant.
更能抵抗輻射。
吸收更多的氧氣。
that you don't want in your body.
George Church has been in the news a lot
喬治.丘奇經常上新聞。
one of these programmable cells
可編碼的細胞,
an entire human genome into a cell,
人類基因組插入細胞當中,
to enhance any of that genome?
to enhance a human body?
to enhance a human body
to enhance a human body?
multidimensional chess board
human genetics by using viruses
來改變人類的基因,
through gene therapy
of those genes in the epigenome
it's not just one little bit,
一點點微小的改變,
to take little portions of it
that's very different.
are very scared by this stuff.
and there are risks to this stuff.
ever want to do this stuff?
to alter the human body
is the universe is 100 percent malevolent.
宇宙是百分之百惡劣的環境。
any one of your bodies at random,
of Mercury, you die.
about 80 percent effective.
只有 80% 是正確的。
upstream eddies of biology
in this rapid torrent of entropy.
that create biological order.
when the Earth becomes very hot,
或是變得炙熱的時候,
when you have supervolcanoes,
當超級火山爆發的時候,
extinction-level events
you can have periodic extinctions.
周期性的地球大滅絕。
five times on Earth,
已經發生過五次了,
is going to go extinct someday.
but maybe 10,000 years after that.
也許是那之後的一萬年。
of the consequence of that,
are common and natural
to diversify our species.
在道德上就變得勢在必行了。
really hard to live on Mars
modify the human body.
to make one cell,
the gravity substantially,
to create your body.
在我們的體內發生。
our bodies as they currently are
暴露在強輻射下,
you have to really redesign things
我們就得重新設計人體。
of Neptune or Jupiter.
(前蘇聯天體物理學家),
in a series of scales.
to alter his or her looks.
for thousands of years.
and you've got this and you've got that.
整整這兒,整整那兒。
take place for medical reasons.
is a different civilization.
fundamental aspects of the body.
身體的基本特徵。
the person grows taller,
使人長的更高,
gets fatter or loses metabolism
讓人變胖或降低新陳代謝,
in a fundamental way.
人體的功能了。
a Life Three civilization,
from what we've got here.
Deinococcus radiodurans
「抗輻射奇異球菌」,
after a lot of exposure to radiation.
之後仍可重新結合。
flow through your blood
直接進入血液當中,
really radical redesigns,
是完全徹底的重新設計,
that's happened in the last decade
發生了一件有趣的事情,
a whole lot of planets out there.
發現了很多的行星。
want to get to these planets,
到達那些行星,
and the rest of this stuff --
還有其它類似的東西——
to the nearest solar system.
beaches somewhere else,
其他星球的海灘上散步,
about something that is very different,
the timescale and the body of humans
absolutely unrecognizable.
to imagine what that might look like,
我們會變成什麽樣子,
take us even that far.
弗洛伊德·瑞姆斯伯格,
that Floyd's been doing
with the basic chemistry of life.
四個字母 ATCG 所組成,
is made in ATCGs, the four letters of DNA.
all animals, all humans, all cows,
動物、人類、牛,
two of those base pairs,
改變其中的兩組鹼基對,
a parallel system to make life,
可以創造生命的平行系統,
可以繁殖、進化,
with most things on Earth
that are immune to all bacteria.
對所有細菌免疫的植物。
that are immune to all viruses.
對所有病毒免疫的植物。
唯一的解決方案。
are not a unique solution.
alternate chemistries to us
造出不同的化學成分,
adaptable to a very different planet
of this experiment,
is based on 20 amino acids.
都是由 20 種氨基酸所組成。
if you say ATCG + XY,
而是用 ATCG + XY,
20 building blocks to 172,
氨基酸增長到 172 種,
172 building blocks of amino acids
基礎氨基酸的模型,
in very different shapes.
is a really weird experiment
hundreds of mouse heads.
上百隻老鼠的頭了。
heart transplants.
太太或女兒叫過來,
the wife or the daughter of the donor
Do you love this person?
the heart is a muscle,
心臟只是一塊肌肉,
or tens of thousands of years,
She took my heart. She broke my heart."
她偷走了我的心,她讓我心碎。」
were transplanted with the heart. Nope.
一同被移植,但並沒有。
remembers what it's afraid of,
memory and consciousness.
interesting question is,
is the only input-output mechanism
那是人體唯一
that consciousness into something
tens of thousands of years,
for a long, long period of time?
all of humanity goes.
人類就不見了。
to alter the human body
want a picture that says,
在一張照片寫著,
survives long-term extinction.
避免被滅絕的方法。
not to evolve the human body
even though it can be challenging,
即使進化可能很困難,
to allow us to explore, live
we can't even dream of today,
grandchildren might someday.
有朝一日才能辦到。
ABOUT THE SPEAKER
Juan Enriquez - FuturistJuan Enriquez thinks and writes about the profound changes that genomics and other life sciences will bring in business, technology, politics and society.
Why you should listen
A broad thinker who studies the intersections of these fields, Enriquez has a talent for bridging disciplines to build a coherent look ahead. He is the managing director of Excel Venture Management, a life sciences VC firm. He recently published (with Steve Gullans) Evolving Ourselves: How Unnatural Selection and Nonrandom Mutation Are Shaping Life on Earth. The book describes a world where humans increasingly shape their environment, themselves and other species.
Enriquez is a member of the board of Synthetic Genomics, which recently introduced the smallest synthetic living cell. Called “JCVI-syn 3.0,” it has 473 genes (about half the previous smallest cell). The organism would die if one of the genes is removed. In other words, this is the minimum genetic instruction set for a living organism.
Juan Enriquez | Speaker | TED.com