Alyson McGregor: Why medicine often has dangerous side effects for women
Alyson McGregor: Zakaj imajo zdravila pogosto nevarne stranske učinke za ženske
Alyson McGregor studies women's health, especially as it relates to emergency care -- when time-sensitive, life-or-death decisions are made using drugs and treatments mainly tested on men. Full bio
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and the medications they're prescribing
in zdravila, ki jih predpišejo
always been the case for everyone.
over the past century
iz zadnjih nekaj stoletij,
half the population?
in a medical emergency.
v nujnih medicinskih primerih.
and stubbed toes,
in udarjenih nožnih prstov,
through the door to the ER,
v urgentno ambulanto,
or gender of our patients.
na spol svojih pacientov.
any differences between men and women.
razlike med moškimi in ženskami.
revealed that 80 percent of the drugs
je pokazala, da je 80 % zdravil
side effects on women
stranske učinke pri ženskah
released to the market?
for a drug to go from an idea
da iz ideje razvijemo zdravilo,
na celicah v laboratoriju,
a regulatory approval process,
nadzora pred odobritvijo.
to prescribe to you?
voljo zdravnikom za predpisovanje.
of dollars of funding
milijonov in milijard dolarjev,
takšnega procesa.
unacceptable side effects
nesprejemljive stranske učinke
after that has gone through?
ko smo opravili ta celoten proces?
used in that laboratory,
ki jih uporabljamo v laboratoriju,
in the animal studies were male animals,
v živalskih študijah, samci
performed almost exclusively on men.
skoraj izključno na moških pacientih.
our framework for medical research?
za naše medicinske raziskave?
popularized in the media,
with the sleep aid Ambien.
over 20 years ago,
pred več kot dvajsetimi leti
of prescriptions have been written,
na stotinam milijonov pacientov,
suffer more sleep disorders than men.
ženske pogosteje motnje spanja.
recommended cutting the dose in half
priporočila prepolovitev doze,
that women metabolize the drug
zdravilo presnavljajo
in their system.
getting behind the wheel of the car,
ko se usedejo za volan avtomobila
for motor vehicle accidents.
ogrožene za prometne nesreče.
as an emergency physician,
that I've cared for over the years
skrbela v preteklih letih,
and acted upon 20 years ago
in primerno ukrepali pred dvajsetimi leti,
to be analyzed by gender?
prinesla veliko sprememb
to protect people
potreba po zaščiti ljudi
without informed consent.
raziskavah brez pristanka.
or rules were set into place,
potrebne smernice oziroma pravila.
to protect women of childbearing age
zaščititi ženske v rodni dobi
medical research studies.
happened to the fetus during the study?
študijo kaj pripetilo zarodku.
at this time actually thought
are pretty homogeneous.
fluctuating levels of hormones
ravni hormonov,
they could get if they had only men.
pridobljene le od moških.
there was a general assumption
were alike in every way,
enaki v vseh pogledih,
and sex hormones.
so opravljali na moških,
applied to women.
uporabljali na ženskah.
of women's health?
koncept ženskega zdravja?
with reproduction:
je postala sinonimna z reprodukcijo:
to as "bikini medicine."
until about the 1980s,
osemdesetih let 20. stoletja,
by the medical community
when they realized that
spoznali,
from all medical research studies
iz medicinskih raziskav,
about the unique needs
of evidence has come to light
men and women are in every way.
moškimi in ženskami na vseh področjih.
a different physiology than normal adults.
fiziologijo kot normalni odrasli.
specialty of pediatrics came to light.
medicinska specializacija pediatrija.
in order to improve their lives.
da bi izboljšali njihova življenja.
can be said about women.
with boobs and tubes.
anatomy and physiology
anatomijo in fiziologijo,
with the same intensity.
intenzivnega preučevanja.
system, for example.
to try to figure out
močno prizadevajo odkriti
completely different heart attacks.
oblike srčnih kapi.
for both men and women,
smrti tako pri moških kot pri ženskah,
of having a heart attack than men.
umre v prvem letu po srčni kapi.
of crushing chest pain --
tiščočo bolečino v prsih...
will complain of "just not feeling right,"
da se "enostavno ne počutijo dobro,"
to označimo za atipično,
women do make up half the population.
ženske predstavljajo polovico populacije.
to help explain some of these differences?
pomagajo pojasniti te razlike?
are smaller in women compared to men,
pri ženskah manjše kot pri moških
develop disease is different
if someone is at risk for a heart attack,
določanje ogroženosti za srčno kap,
and tested and perfected in men,
in izpopolnjeni za moške
at determining that in women.
delujejo enako dobro.
about the medications --
that we use, like aspirin.
na primer Aspirin.
prevent them from having a heart attack,
da preprečimo srčno kap.
give aspirin to a healthy woman,
Aspirina zdravim ženskam
is a fast-paced business.
naglo razvijajoče-se področje.
področjih medicine,
men and women that we could be utilizing?
ki bi jih lahko s pridom uporabljali?
get those runny noses
nekateri pogosteje prehlajeni
to those stubbed toes
pri tistih udarninah prstov
every cell has a sex.
da ima vsaka celica spol.
presents themselves in society.
kako se človek predstavlja v družbi.
transgendered population.
that from the moment of conception,
da od trenutka spočetja
the chromosomes that determine
ki določajo
male or female, man or woman.
chromosomes pictured here --
would be born with ovaries or testes,
rodil z jajčniki ali testisi.
that those organs produced
ki jih ta organa izdelujeta,
we see in the opposite sex.
ostale razlike med spoloma.
that theory was wrong --
from the Whitehead Institute,
iz Inštituta Whitehead,
that those sex-determining chromosomes
for our entire lives
for the differences we see
between men and women
and severity of diseases.
in resnosti bolezni.
that continue to find that evidence,
z odkrivanjem novih dokazov,
to start translating this data
da pričnejo uporabljati te podatke
of a national organization
soustanoviteljica nacionalne zveze
Women's Health Collaborative,
so that it's available for teaching
zato da so dostopni za poučevanje
the medical educators to the table.
medicinske izobraževalne ustanove.
has been done since its inception.
ki je bil uveljavljen od samega začetka.
of incorporating the gender lens
vključitve razlik med spoloma
health care providers correctly.
bodoče izvajalce zdravstvenih storitev.
the Department of Emergency Medicine
znotraj oddelka za urgentno medicino
in Emergency Medicine,
the differences between men and women
ugotavljamo razlike med spoloma
and sepsis and substance abuse,
sepsi in zlorabi prepovedanih drog.
that education is paramount.
izobraževanje ključno.
model of education.
model izobrazbe.
for the nurses, for the students
medicinske tehnike, študente
to the health care leaders.
le izvajalcem zdravstvenih storitev.
sedanjega stanja.
da to ni preprosto.
we think about medicine
kako razmišljamo o medicini,
to the health care system.
zdravstvenega sistema.
on the wheels of inevitability,
towards change is awareness.
pa je zavedanje.
medical care for women.
zdravstvene oskrbe za ženske.
individualized health care for everyone.
zdravstveno oskrbo za vse.
medical care for men and women.
oskrbo tako za moške kot za ženske.
to ask your doctors
svojega zdravnika
are specific to your sex and gender.
namenjena prav vašemu spolu.
and together we can all learn.
in skupaj se lahko vsi učimo.
and my colleagues in this field,
kolege na tem področju
ABOUT THE SPEAKER
Alyson McGregor - Women's health pioneerAlyson McGregor studies women's health, especially as it relates to emergency care -- when time-sensitive, life-or-death decisions are made using drugs and treatments mainly tested on men.
Why you should listen
Alyson J. McGregor MD is co-founder and director for the Sex and Gender in Emergency Medicine (SGEM) Division (formerly Women’s Health in Emergency Care) within the Department of Emergency Medicine at Warren Alpert Medical School of Brown University.
Her group's aim is to establish research and educational endeavors that promote sex- and gender-specific medicine and women’s health as they relate to emergency care. Dr. McGregor received her medical degree at Boston University School of Medicine and residency training at Brown, where she continues to work as an attending physician at RI Hospital Emergency Department. Dr. McGregor is an Associate Professor of Emergency Medicine and also serves as co-director for the SGEM Fellowship and co-founder of the national organization Sex and Gender Women’s Health Collaborative.
Alyson McGregor | Speaker | TED.com