ABOUT THE SPEAKER
Lee Cronin - Chemist
A professor of chemistry, nanoscience and chemical complexity, Lee Cronin and his research group investigate how chemistry can revolutionize modern technology and even create life.

Why you should listen

Lee Cronin's lab at the University of Glasgow does cutting-edge research into how complex chemical systems, created from non-biological building blocks, can have real-world applications with wide impact. At TEDGlobal 2012, Cronin shared some of the lab's latest work: creating a 3D printer for molecules. This device -- which has been prototyped -- can download plans for molecules and print them, in the same way that a 3D printer creates objects. In the future, Cronin says this technology could potentially be used to print medicine -- cheaply and wherever it is needed. As Cronin says: "What Apple did for music, I'd like to do for the discovery and distribution of prescription drugs."

At TEDGlobal 2011, Cronin shared his lab's bold plan to create life. At the moment, bacteria is the minimum unit of life -- the smallest chemical unit that can undergo evolution. But in Cronin's emerging field, he's thinking about forms of life that won't be biological. To explore this, and to try to understand how life itself originated from chemicals, Cronin and others are attempting to create truly artificial life from completely non-biological chemistries that mimic the behavior of natural cells. They call these chemical cells, or Chells. 

Cronin's research interests also encompass self-assembly and self-growing structures -- the better to assemble life at nanoscale. At the University of Glasgow, this work on crystal structures is producing a raft of papers from his research group. He says: "Basically one of my longstanding research goals is to understand how life emerged on planet Earth and re-create the process."

Read the papers referenced in his TEDGlobal 2102 talk:

Integrated 3D-printed reactionware for chemical synthesis and analysis, Nature Chemistry

Configurable 3D-Printed millifluidic and microfluidic ‘lab on a chip’ reactionware devices, Lab on a Chip

More profile about the speaker
Lee Cronin | Speaker | TED.com
TEDGlobal 2012

Lee Cronin: Print your own medicine

Lee Cronin: Print din egen medicin

Filmed:
1,045,687 views

Kemiker Lee Cronin arbejder på en 3D-printer, som - i stedet for ting - er i stand til at printe molekyler. En spændende mulig anvendelse på langt sigt: Du kan printe din egen medicin ved hjælp af kemisk 'blæk'.
- Chemist
A professor of chemistry, nanoscience and chemical complexity, Lee Cronin and his research group investigate how chemistry can revolutionize modern technology and even create life. Full bio

Double-click the English transcript below to play the video.

00:16
OrganicØkologisk chemistskemikere make moleculesmolekyler,
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Organiske kemikere laver molekyler,
00:19
very complicatedkompliceret moleculesmolekyler,
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meget komplicerede molekyler,
00:21
by choppingskærebræt up a bigstor moleculemolekyle into smalllille moleculesmolekyler
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ved at hakke et stort molekyle i stykker til mindre molekyler
00:24
and reversebagside engineeringingeniørarbejde.
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og lave reverse engineering.
00:26
And as a chemistkemiker,
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Og som kemiker
00:27
one of the things I wanted to askSpørg my researchforskning groupgruppe a couplepar of yearsflere år agosiden is,
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var en af de ting, jeg for et par år siden ville spørge min forskningsgruppe om
00:31
could we make a really coolfedt nok universaluniversel chemistrykemi setsæt?
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ville vi kunne lave et virkelig sejt, universelt kemisæt?
00:35
In essenceessens, could we "appapp" chemistrykemi?
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Skåret ind til benet, ville vi kunne lave kemi som en "app"?
00:40
Now what would this mean, and how would we do it?
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Okay, hvad ville det betyde, og hvordan skulle vi gøre det?
00:43
Well to startStart to do this,
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For at komme i gang
00:45
we tooktog a 3D printerprinter
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tog vi en 3D-printer
00:47
and we startedstartede to printPrint our beakersbægre and our testprøve tubesrør on one sideside
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og begyndte at printe vores bægre og reagensglas på den ene side
00:51
and then printPrint the moleculemolekyle at the samesamme time on the other sideside
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og samtidig printe molekylet på den anden side
00:55
and combineforene them togethersammen in what we call reactionwarereactionware.
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og kombinere dem til, hvad vi kalder 'reactionware'.
00:58
And so by printingtrykning the vesselbeholder and doing the chemistrykemi at the samesamme time,
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Så ved at lave stoffet og kemien samtidig
01:03
we maykan startStart to accessadgang this universaluniversel toolkitToolkit of chemistrykemi.
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kommer vi tættere på sådan en universel kemi-værktøjskasse.
01:08
Now what could this mean?
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Men hvad ville det betyde?
01:09
Well if we can embedindlejre biologicalbiologisk and chemicalkemisk networksnetværk like a searchSøg enginemotor,
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Hvis vi kan samle biologiske og kemiske netværk i en søgemaskine,
01:15
so if you have a cellcelle that's illsyg that you need to curehelbrede
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så hvis du har en celle, der er syg og skal kureres
01:18
or bacteriabakterie that you want to killdræbe,
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eller bakterier, du vil slå ihjel,
01:20
if you have this embeddedindlejret in your deviceenhed
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hvis du har det indbygget i dit apparat
01:22
at the samesamme time, and you do the chemistrykemi,
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samtidig, og du laver kemien,
01:24
you maykan be ablei stand to make drugsstoffer in a newny way.
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kan du måske lave lægemidler på en ny måde.
01:28
So how are we doing this in the lablab?
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Hvordan gør vi det i laboratoriet?
01:30
Well it requireskræver softwaresoftware, it requireskræver hardwarehardware
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Det kræver software, det kræver hardware,
01:33
and it requireskræver chemicalkemisk inksblæk.
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og det kræver kemisk 'blæk'.
01:36
And so the really coolfedt nok bitbit is,
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Så det rigtigt seje er,
01:37
the ideaide is that we want to have a universaluniversel setsæt of inksblæk
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tanken er, at vi skal have et universelt sæt af kemisk blæk,
01:40
that we put out with the printerprinter,
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som vi 'skriver ud' på printeren,
01:43
and you downloadHent the blueprinthandleplanen, the organicorganisk chemistrykemi for that moleculemolekyle
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og du downloader en opskrift - molekylets organiske kemi
01:47
and you make it in the deviceenhed.
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og du laver det med apparatet.
01:50
And so you can make your moleculemolekyle in the printerprinter usingved brug af this softwaresoftware.
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Så kan du lave dit molekyle i printeren ved at bruge softwaren.
01:55
So what could this mean?
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Hvad vil det betyde?
01:58
Well, ultimatelyultimativt, it could mean that you could printPrint your ownegen medicinemedicin.
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I sidste ende kunne det betyde, at du vil kunne printe din egen medicin.
02:03
And this is what we're doing in the lablab at the momentøjeblik.
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Og det er, hvad vi gør i laboratoriet for tiden.
02:05
But to take babybaby stepstrin to get there,
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Men for at komme derhen med små skridt
02:06
first of all we want to look at drugmedicin designdesign and productionproduktion,
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vil vi først se på design og produktion af lægemidler,
02:09
or drugmedicin discoveryopdagelse and manufacturingfremstilling.
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eller opdagelse og fremstilling af lægemidler.
02:12
Because if we can manufacturefremstille it after we'vevi har discoveredopdaget it,
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For hvis vi kan fremstille det, når vi har opdaget det,
02:15
we could deployimplementere it anywhereoveralt.
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vil vi kunne sætte det ind hvor som helst.
02:17
You don't need to go to the chemistkemiker anymorelængere.
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Så behøver du ikke mere gå på apoteket.
02:19
We can printPrint drugsstoffer at pointpunkt of need.
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Vi kan printe lægemidlerne der, hvor der er brug for dem.
02:22
We can downloadHent newny diagnosticsdiagnostik.
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Vi kan downloade nye diagnoser.
02:24
Say a newny supersuper buginsekt has emergedopstået.
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Forestil dig en ny, aggressiv infektionssygdom.
02:26
You put it in your searchSøg enginemotor,
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Du taster den ind i din søgemaskine,
02:28
and you createskab the drugmedicin to treatbehandle the threattrussel.
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og du skaber medicinen til at behandle truslen.
02:31
So this allowstillader you on-the-flyon-the-fly molecularmolekylær assemblymontage.
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Det her giver dig mulighed for at samle molekyler med det samme.
02:35
But perhapsmåske for me the corekerne bitbit going into the futurefremtid
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Men for mig er det centrale i fremtiden
02:38
is this ideaide of takingtager your ownegen stemstilk cellsceller,
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ideen om at tage dine egne stamceller,
02:41
with your genesgener and your environmentmiljø,
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med dine gener i dit eget miljø
02:43
and you printPrint your ownegen personalpersonlig medicinemedicin.
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og printe din egen personlige medicin.
02:46
And if that doesn't seemsynes fancifulfantasifulde enoughnok,
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Og hvis det ikke er vildt nok,
02:48
where do you think we're going to go?
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hvor tror du så vi er på vej hen?
02:50
Well, you're going to have your ownegen personalpersonlig matterstof fabricatorfabrikator.
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Du kan få din egen personlige stof-generator.
02:55
BeamBeam me up, ScottyScotty.
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Beam me up, Scotty.
02:57
(ApplauseBifald)
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(Bifald)
Translated by Tune Kristensen
Reviewed by Anders Finn Jørgensen

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ABOUT THE SPEAKER
Lee Cronin - Chemist
A professor of chemistry, nanoscience and chemical complexity, Lee Cronin and his research group investigate how chemistry can revolutionize modern technology and even create life.

Why you should listen

Lee Cronin's lab at the University of Glasgow does cutting-edge research into how complex chemical systems, created from non-biological building blocks, can have real-world applications with wide impact. At TEDGlobal 2012, Cronin shared some of the lab's latest work: creating a 3D printer for molecules. This device -- which has been prototyped -- can download plans for molecules and print them, in the same way that a 3D printer creates objects. In the future, Cronin says this technology could potentially be used to print medicine -- cheaply and wherever it is needed. As Cronin says: "What Apple did for music, I'd like to do for the discovery and distribution of prescription drugs."

At TEDGlobal 2011, Cronin shared his lab's bold plan to create life. At the moment, bacteria is the minimum unit of life -- the smallest chemical unit that can undergo evolution. But in Cronin's emerging field, he's thinking about forms of life that won't be biological. To explore this, and to try to understand how life itself originated from chemicals, Cronin and others are attempting to create truly artificial life from completely non-biological chemistries that mimic the behavior of natural cells. They call these chemical cells, or Chells. 

Cronin's research interests also encompass self-assembly and self-growing structures -- the better to assemble life at nanoscale. At the University of Glasgow, this work on crystal structures is producing a raft of papers from his research group. He says: "Basically one of my longstanding research goals is to understand how life emerged on planet Earth and re-create the process."

Read the papers referenced in his TEDGlobal 2102 talk:

Integrated 3D-printed reactionware for chemical synthesis and analysis, Nature Chemistry

Configurable 3D-Printed millifluidic and microfluidic ‘lab on a chip’ reactionware devices, Lab on a Chip

More profile about the speaker
Lee Cronin | Speaker | TED.com

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