ABOUT THE SPEAKER
Lee Cronin - Chemist
A professor of chemistry, nanoscience and chemical complexity, Lee Cronin and his research group investigate how chemistry can revolutionize modern technology and even create life.

Why you should listen

Lee Cronin's lab at the University of Glasgow does cutting-edge research into how complex chemical systems, created from non-biological building blocks, can have real-world applications with wide impact. At TEDGlobal 2012, Cronin shared some of the lab's latest work: creating a 3D printer for molecules. This device -- which has been prototyped -- can download plans for molecules and print them, in the same way that a 3D printer creates objects. In the future, Cronin says this technology could potentially be used to print medicine -- cheaply and wherever it is needed. As Cronin says: "What Apple did for music, I'd like to do for the discovery and distribution of prescription drugs."

At TEDGlobal 2011, Cronin shared his lab's bold plan to create life. At the moment, bacteria is the minimum unit of life -- the smallest chemical unit that can undergo evolution. But in Cronin's emerging field, he's thinking about forms of life that won't be biological. To explore this, and to try to understand how life itself originated from chemicals, Cronin and others are attempting to create truly artificial life from completely non-biological chemistries that mimic the behavior of natural cells. They call these chemical cells, or Chells. 

Cronin's research interests also encompass self-assembly and self-growing structures -- the better to assemble life at nanoscale. At the University of Glasgow, this work on crystal structures is producing a raft of papers from his research group. He says: "Basically one of my longstanding research goals is to understand how life emerged on planet Earth and re-create the process."

Read the papers referenced in his TEDGlobal 2102 talk:

Integrated 3D-printed reactionware for chemical synthesis and analysis, Nature Chemistry

Configurable 3D-Printed millifluidic and microfluidic ‘lab on a chip’ reactionware devices, Lab on a Chip

More profile about the speaker
Lee Cronin | Speaker | TED.com
TEDGlobal 2012

Lee Cronin: Print your own medicine

李 克罗宁:打印你自己的药物

Filmed:
1,045,687 views

化学家李.克罗宁在研究一种能打印分子的3D打印机。一个令人兴奋且很有潜力的长期应用程式:利用化学链接来打印你自己的药物。
- Chemist
A professor of chemistry, nanoscience and chemical complexity, Lee Cronin and his research group investigate how chemistry can revolutionize modern technology and even create life. Full bio

Double-click the English transcript below to play the video.

00:16
Organic有机 chemists化学家 make molecules分子,
0
763
2615
有机化学家制作分子,
00:19
very complicated复杂 molecules分子,
1
3378
1816
非常复杂的分子,
00:21
by chopping斩波 up a big molecule分子 into small molecules分子
2
5194
3684
把大的分子割成小的
00:24
and reverse相反 engineering工程.
3
8878
1861
再反过来。
00:26
And as a chemist化学家,
4
10739
1039
作为一名化学家,
00:27
one of the things I wanted to ask my research研究 group a couple一对 of years年份 ago is,
5
11778
3467
我几年前便问我的研究小组,
00:31
could we make a really cool universal普遍 chemistry化学 set?
6
15245
4151
我们可能做出很酷的通用化学设置吗?
00:35
In essence本质, could we "app应用" chemistry化学?
7
19396
5033
本质上讲,我们可以把化学软件化吗?
00:40
Now what would this mean, and how would we do it?
8
24429
3183
这意味什么,我们又可以怎么做?
00:43
Well to start开始 to do this,
9
27612
1971
这样开始吧,
00:45
we took a 3D printer打印机
10
29583
1732
我们用一台3D打印机
00:47
and we started开始 to print打印 our beakers烧杯 and our test测试 tubes on one side
11
31315
4302
开始把我们烧杯和试管打印在一面
00:51
and then print打印 the molecule分子 at the same相同 time on the other side
12
35617
4065
然后在另一面同时打印上分子
00:55
and combine结合 them together一起 in what we call reactionwarereactionware.
13
39682
3154
然后将两者在我们称之为感应件的仪器当中合并。
00:58
And so by printing印花 the vessel船只 and doing the chemistry化学 at the same相同 time,
14
42836
4434
打印容器的同时,进性化学过程
01:03
we may可能 start开始 to access访问 this universal普遍 toolkit工具包 of chemistry化学.
15
47270
5167
我们可能会开始接近这个通用的化学工具箱。
01:08
Now what could this mean?
16
52437
1548
这又意味什么?
01:09
Well if we can embed biological生物 and chemical化学 networks网络 like a search搜索 engine发动机,
17
53985
5268
如果我们可把生物和化学网络做成像搜索引擎一样,
01:15
so if you have a cell细胞 that's ill生病 that you need to cure治愈
18
59253
3149
当您有哪个细胞生病了,需要治愈
01:18
or bacteria that you want to kill,
19
62402
1719
或你想杀菌,
01:20
if you have this embedded嵌入式 in your device设备
20
64121
2331
若您将这组件嵌在您的设备里
01:22
at the same相同 time, and you do the chemistry化学,
21
66452
2449
同时,你进行化学过程
01:24
you may可能 be able能够 to make drugs毒品 in a new way.
22
68901
3601
您便可以用新方法做出药品。
01:28
So how are we doing this in the lab实验室?
23
72502
2400
那么,我们如何在实验室中做这个呢?
01:30
Well it requires要求 software软件, it requires要求 hardware硬件
24
74902
3099
它需要软件和硬件
01:33
and it requires要求 chemical化学 inks油墨.
25
78001
2366
它也需要化学油墨。
01:36
And so the really cool bit is,
26
80367
1453
最酷的一点是,
01:37
the idea理念 is that we want to have a universal普遍 set of inks油墨
27
81820
3047
我们想要一套通用的油墨
01:40
that we put out with the printer打印机,
28
84867
2269
可以和打印机一同推出
01:43
and you download下载 the blueprint蓝图, the organic有机 chemistry化学 for that molecule分子
29
87136
4282
您下载蓝图,您需要的分子的有机化学过程
01:47
and you make it in the device设备.
30
91418
3000
在该设备里做。
01:50
And so you can make your molecule分子 in the printer打印机 using运用 this software软件.
31
94418
5567
因此,你可以用这套软件造你的分子。
01:55
So what could this mean?
32
99985
2199
这意味什么?
01:58
Well, ultimately最终, it could mean that you could print打印 your own拥有 medicine医学.
33
102184
4947
最终,这意味您可以打印你自己的药。
02:03
And this is what we're doing in the lab实验室 at the moment时刻.
34
107131
1969
而这是我们目前在实验室里所做。
02:05
But to take baby宝宝 steps脚步 to get there,
35
109100
1902
但是,要一步步的达到那里,
02:06
first of all we want to look at drug药物 design设计 and production生产,
36
111002
2833
首先,我们在看药物的设计和产品,
02:09
or drug药物 discovery发现 and manufacturing制造业.
37
113835
2650
或药物的发现和制造。
02:12
Because if we can manufacture制造 it after we've我们已经 discovered发现 it,
38
116485
2999
因为如果我们能找到它,制造它,
02:15
we could deploy部署 it anywhere随地.
39
119484
2134
我们便可以任何地方调配它。
02:17
You don't need to go to the chemist化学家 anymore.
40
121618
2116
您再也不需要去找化学家。
02:19
We can print打印 drugs毒品 at point of need.
41
123734
2368
我们可以打印需要的药品。
02:22
We can download下载 new diagnostics诊断.
42
126102
2655
我们可以下载新的诊断方法。
02:24
Say a new super bug窃听器 has emerged出现.
43
128757
2011
那么说,一个新的超级"bug"已经出现。
02:26
You put it in your search搜索 engine发动机,
44
130768
1617
把它放到你的搜索引擎,
02:28
and you create创建 the drug药物 to treat对待 the threat威胁.
45
132385
3133
您就可以创建药物来治疗病痛。
02:31
So this allows允许 you on-the-fly在即时 molecular分子 assembly部件.
46
135518
3688
这允许您随时进行分子组装。
02:35
But perhaps也许 for me the core核心 bit going into the future未来
47
139206
2995
但,对我来说,未来最核心的部分
02:38
is this idea理念 of taking服用 your own拥有 stem cells细胞,
48
142201
3350
是照你自己的干细胞,
02:41
with your genes基因 and your environment环境,
49
145551
1767
结合你的基因和环境,
02:43
and you print打印 your own拥有 personal个人 medicine医学.
50
147318
3449
来打印你自己须要的药。
02:46
And if that doesn't seem似乎 fanciful撒娇的 enough足够,
51
150767
2252
如果这看起来还不够科幻的话,
02:48
where do you think we're going to go?
52
153019
2048
你觉得我们该往哪方向去?
02:50
Well, you're going to have your own拥有 personal个人 matter fabricator制造者.
53
155067
4584
嗯,你也要有自己的计划喔。
02:55
Beam光束 me up, Scotty.
54
159651
1900
把我传上飞船。(电视剧"Star Trek"的标志性台词)
02:57
(Applause掌声)
55
161551
3349
(掌声)
Translated by Xue Chen
Reviewed by Sharon Loh

▲Back to top

ABOUT THE SPEAKER
Lee Cronin - Chemist
A professor of chemistry, nanoscience and chemical complexity, Lee Cronin and his research group investigate how chemistry can revolutionize modern technology and even create life.

Why you should listen

Lee Cronin's lab at the University of Glasgow does cutting-edge research into how complex chemical systems, created from non-biological building blocks, can have real-world applications with wide impact. At TEDGlobal 2012, Cronin shared some of the lab's latest work: creating a 3D printer for molecules. This device -- which has been prototyped -- can download plans for molecules and print them, in the same way that a 3D printer creates objects. In the future, Cronin says this technology could potentially be used to print medicine -- cheaply and wherever it is needed. As Cronin says: "What Apple did for music, I'd like to do for the discovery and distribution of prescription drugs."

At TEDGlobal 2011, Cronin shared his lab's bold plan to create life. At the moment, bacteria is the minimum unit of life -- the smallest chemical unit that can undergo evolution. But in Cronin's emerging field, he's thinking about forms of life that won't be biological. To explore this, and to try to understand how life itself originated from chemicals, Cronin and others are attempting to create truly artificial life from completely non-biological chemistries that mimic the behavior of natural cells. They call these chemical cells, or Chells. 

Cronin's research interests also encompass self-assembly and self-growing structures -- the better to assemble life at nanoscale. At the University of Glasgow, this work on crystal structures is producing a raft of papers from his research group. He says: "Basically one of my longstanding research goals is to understand how life emerged on planet Earth and re-create the process."

Read the papers referenced in his TEDGlobal 2102 talk:

Integrated 3D-printed reactionware for chemical synthesis and analysis, Nature Chemistry

Configurable 3D-Printed millifluidic and microfluidic ‘lab on a chip’ reactionware devices, Lab on a Chip

More profile about the speaker
Lee Cronin | Speaker | TED.com

Data provided by TED.

This site was created in May 2015 and the last update was on January 12, 2020. It will no longer be updated.

We are currently creating a new site called "eng.lish.video" and would be grateful if you could access it.

If you have any questions or suggestions, please feel free to write comments in your language on the contact form.

Privacy Policy

Developer's Blog

Buy Me A Coffee