ABOUT THE SPEAKER
Lee Cronin - Chemist
A professor of chemistry, nanoscience and chemical complexity, Lee Cronin and his research group investigate how chemistry can revolutionize modern technology and even create life.

Why you should listen

Lee Cronin's lab at the University of Glasgow does cutting-edge research into how complex chemical systems, created from non-biological building blocks, can have real-world applications with wide impact. At TEDGlobal 2012, Cronin shared some of the lab's latest work: creating a 3D printer for molecules. This device -- which has been prototyped -- can download plans for molecules and print them, in the same way that a 3D printer creates objects. In the future, Cronin says this technology could potentially be used to print medicine -- cheaply and wherever it is needed. As Cronin says: "What Apple did for music, I'd like to do for the discovery and distribution of prescription drugs."

At TEDGlobal 2011, Cronin shared his lab's bold plan to create life. At the moment, bacteria is the minimum unit of life -- the smallest chemical unit that can undergo evolution. But in Cronin's emerging field, he's thinking about forms of life that won't be biological. To explore this, and to try to understand how life itself originated from chemicals, Cronin and others are attempting to create truly artificial life from completely non-biological chemistries that mimic the behavior of natural cells. They call these chemical cells, or Chells. 

Cronin's research interests also encompass self-assembly and self-growing structures -- the better to assemble life at nanoscale. At the University of Glasgow, this work on crystal structures is producing a raft of papers from his research group. He says: "Basically one of my longstanding research goals is to understand how life emerged on planet Earth and re-create the process."

Read the papers referenced in his TEDGlobal 2102 talk:

Integrated 3D-printed reactionware for chemical synthesis and analysis, Nature Chemistry

Configurable 3D-Printed millifluidic and microfluidic ‘lab on a chip’ reactionware devices, Lab on a Chip

More profile about the speaker
Lee Cronin | Speaker | TED.com
TEDGlobal 2012

Lee Cronin: Print your own medicine

Lee Cronin: Imprima seu próprio medicamento

Filmed:
1,045,687 views

O químico Lee Cronin está trabalhando em uma impressora 3D que, em vez de objetos, é capaz de imprimir moléculas. Uma aplicação potencial de longo prazo entusiasmante: imprimir seus próprios medicamentos usando tintas químicas.
- Chemist
A professor of chemistry, nanoscience and chemical complexity, Lee Cronin and his research group investigate how chemistry can revolutionize modern technology and even create life. Full bio

Double-click the English transcript below to play the video.

00:16
Organic chemists make molecules,
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Químicos orgânicos criam moléculas,
00:19
very complicated molecules,
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moléculas muito complicadas,
00:21
by chopping up a big molecule into small molecules
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através da quebra de uma molécula grande em outras pequenas
00:24
and reverse engineering.
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e pela engenharia reversa.
00:26
And as a chemist,
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E como químico,
00:27
one of the things I wanted to ask my research group a couple of years ago is,
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uma das coisas que queria perguntar ao meu grupo de pesquisa, alguns anos atrás, era se
00:31
could we make a really cool universal chemistry set?
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poderíamos criar um conjunto universal de química bem legal?
00:35
In essence, could we "app" chemistry?
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Em resumo, poderíamos ter um "aplicativo" de química?
00:40
Now what would this mean, and how would we do it?
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Bem, o que isto significaria e como poderíamos fazer isso?
00:43
Well to start to do this,
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Para começar a fazer isso,
00:45
we took a 3D printer
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pegamos uma impressora 3D
00:47
and we started to print our beakers and our test tubes on one side
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e começamos a imprimir nossas provetas e tubos de ensaio de um lado,
00:51
and then print the molecule at the same time on the other side
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e a imprimir a molécula, ao mesmo tempo, do outro lado
00:55
and combine them together in what we call reactionware.
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e a combiná-los naquilo que chamamos aparato de reação.
00:58
And so by printing the vessel and doing the chemistry at the same time,
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E dessa forma, ao imprimir o recipiente e criar a fórmula química ao mesmo tempo,
01:03
we may start to access this universal toolkit of chemistry.
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talvez possamos começar a acessar essa caixa de ferramentas universal de química.
01:08
Now what could this mean?
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Bem, o que isto poderia significar?
01:09
Well if we can embed biological and chemical networks like a search engine,
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Se pudermos integrar redes biológicas e químicas como um motor de busca,
01:15
so if you have a cell that's ill that you need to cure
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então, se você tem uma célula doente que precisa curar
01:18
or bacteria that you want to kill,
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ou uma bactéria que quer eliminar,
01:20
if you have this embedded in your device
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caso você tenha isto integrado em seu dispositivo
01:22
at the same time, and you do the chemistry,
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ao mesmo tempo, e criar a fórmula química,
01:24
you may be able to make drugs in a new way.
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você pode ser capaz de fabricar drogas de uma nova maneira.
01:28
So how are we doing this in the lab?
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E como estamos fazendo isto no laboratório?
01:30
Well it requires software, it requires hardware
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Bem, isso requer 'software', requer equipamento
01:33
and it requires chemical inks.
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e requer tintas químicas.
01:36
And so the really cool bit is,
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Então, a parte realmente legal é:
01:37
the idea is that we want to have a universal set of inks
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a ideia é que queremos ter um conjunto universal de tintas
01:40
that we put out with the printer,
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que disponibilizamos com a impressora,
01:43
and you download the blueprint, the organic chemistry for that molecule
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e você baixa o diagrama, a química orgânica para aquela molécula
01:47
and you make it in the device.
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e cria isso no dispositivo.
01:50
And so you can make your molecule in the printer using this software.
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E assim você pode fazer sua molécula na impressora usando esse software.
01:55
So what could this mean?
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O que isto poderia significar?
01:58
Well, ultimately, it could mean that you could print your own medicine.
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Bem, no final, isto significaria que você poderia imprimir seu próprio remédio.
02:03
And this is what we're doing in the lab at the moment.
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E isso é o que estamos fazendo no laboratório agora.
02:05
But to take baby steps to get there,
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Mas, ao dar os primeiros passos para chegar lá,
02:06
first of all we want to look at drug design and production,
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antes de mais nada, queremos observar o 'design' e produção da droga
02:09
or drug discovery and manufacturing.
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ou a descoberta e fabricação da droga.
02:12
Because if we can manufacture it after we've discovered it,
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Porque, se pudermos fabricá-la depois que a decobrirmos,
02:15
we could deploy it anywhere.
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poderemos distribuí-la para qualquer lugar.
02:17
You don't need to go to the chemist anymore.
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Você não precisa mais ir até o químico.
02:19
We can print drugs at point of need.
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Podemos imprimir drogas onde forem necessárias.
02:22
We can download new diagnostics.
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Podemos baixar novos diagnósticos.
02:24
Say a new super bug has emerged.
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Digamos que surgiu um nova super bactéria.
02:26
You put it in your search engine,
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Você a coloca em seu motor de busca
02:28
and you create the drug to treat the threat.
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e cria a droga para combater a ameaça.
02:31
So this allows you on-the-fly molecular assembly.
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Então isso lhe proporciona uma linha de montagem molecular instantânea.
02:35
But perhaps for me the core bit going into the future
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Talvez para mim, o aspecto central, no futuro,
02:38
is this idea of taking your own stem cells,
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seja a ideia de pegar suas próprias células tronco,
02:41
with your genes and your environment,
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com seus genes e seu ambiente,
02:43
and you print your own personal medicine.
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e você mesmo imprimir seu medicamento personalizado.
02:46
And if that doesn't seem fanciful enough,
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E se isso não parece fantástico o bastante,
02:48
where do you think we're going to go?
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para onde você acha que iremos?
02:50
Well, you're going to have your own personal matter fabricator.
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Bem, você vai ter seu própria produtor de matéria.
02:55
Beam me up, Scotty.
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Teleporte-me, Scotty.
02:57
(Applause)
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(Aplausos)
Translated by Isabel Villan
Reviewed by Debora Policarpo

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ABOUT THE SPEAKER
Lee Cronin - Chemist
A professor of chemistry, nanoscience and chemical complexity, Lee Cronin and his research group investigate how chemistry can revolutionize modern technology and even create life.

Why you should listen

Lee Cronin's lab at the University of Glasgow does cutting-edge research into how complex chemical systems, created from non-biological building blocks, can have real-world applications with wide impact. At TEDGlobal 2012, Cronin shared some of the lab's latest work: creating a 3D printer for molecules. This device -- which has been prototyped -- can download plans for molecules and print them, in the same way that a 3D printer creates objects. In the future, Cronin says this technology could potentially be used to print medicine -- cheaply and wherever it is needed. As Cronin says: "What Apple did for music, I'd like to do for the discovery and distribution of prescription drugs."

At TEDGlobal 2011, Cronin shared his lab's bold plan to create life. At the moment, bacteria is the minimum unit of life -- the smallest chemical unit that can undergo evolution. But in Cronin's emerging field, he's thinking about forms of life that won't be biological. To explore this, and to try to understand how life itself originated from chemicals, Cronin and others are attempting to create truly artificial life from completely non-biological chemistries that mimic the behavior of natural cells. They call these chemical cells, or Chells. 

Cronin's research interests also encompass self-assembly and self-growing structures -- the better to assemble life at nanoscale. At the University of Glasgow, this work on crystal structures is producing a raft of papers from his research group. He says: "Basically one of my longstanding research goals is to understand how life emerged on planet Earth and re-create the process."

Read the papers referenced in his TEDGlobal 2102 talk:

Integrated 3D-printed reactionware for chemical synthesis and analysis, Nature Chemistry

Configurable 3D-Printed millifluidic and microfluidic ‘lab on a chip’ reactionware devices, Lab on a Chip

More profile about the speaker
Lee Cronin | Speaker | TED.com

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