ABOUT THE SPEAKER
Lee Cronin - Chemist
A professor of chemistry, nanoscience and chemical complexity, Lee Cronin and his research group investigate how chemistry can revolutionize modern technology and even create life.

Why you should listen

Lee Cronin's lab at the University of Glasgow does cutting-edge research into how complex chemical systems, created from non-biological building blocks, can have real-world applications with wide impact. At TEDGlobal 2012, Cronin shared some of the lab's latest work: creating a 3D printer for molecules. This device -- which has been prototyped -- can download plans for molecules and print them, in the same way that a 3D printer creates objects. In the future, Cronin says this technology could potentially be used to print medicine -- cheaply and wherever it is needed. As Cronin says: "What Apple did for music, I'd like to do for the discovery and distribution of prescription drugs."

At TEDGlobal 2011, Cronin shared his lab's bold plan to create life. At the moment, bacteria is the minimum unit of life -- the smallest chemical unit that can undergo evolution. But in Cronin's emerging field, he's thinking about forms of life that won't be biological. To explore this, and to try to understand how life itself originated from chemicals, Cronin and others are attempting to create truly artificial life from completely non-biological chemistries that mimic the behavior of natural cells. They call these chemical cells, or Chells. 

Cronin's research interests also encompass self-assembly and self-growing structures -- the better to assemble life at nanoscale. At the University of Glasgow, this work on crystal structures is producing a raft of papers from his research group. He says: "Basically one of my longstanding research goals is to understand how life emerged on planet Earth and re-create the process."

Read the papers referenced in his TEDGlobal 2102 talk:

Integrated 3D-printed reactionware for chemical synthesis and analysis, Nature Chemistry

Configurable 3D-Printed millifluidic and microfluidic ‘lab on a chip’ reactionware devices, Lab on a Chip

More profile about the speaker
Lee Cronin | Speaker | TED.com
TEDGlobal 2012

Lee Cronin: Print your own medicine

リー・クローニン: 自分専用の薬を印刷しよう

Filmed:
1,045,687 views

化学者リー・クローニンは、物体ではなく、分子を印刷することができる3Dプリンターの開発に取り組んでいます。これが応用できれば将来は化学物質をインクとして自分専用の薬を印刷するという驚くべき可能性も期待できそうです。
- Chemist
A professor of chemistry, nanoscience and chemical complexity, Lee Cronin and his research group investigate how chemistry can revolutionize modern technology and even create life. Full bio

Double-click the English transcript below to play the video.

00:16
Organicオーガニック chemists化学者 make molecules分子,
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有機化学者は
00:19
very complicated複雑な molecules分子,
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大きな分子を切ったり
00:21
by choppingチョッピング up a big大きい molecule分子 into small小さい molecules分子
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既存の分子を分析して
00:24
and reverse engineeringエンジニアリング.
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複雑な分子を作ります
00:26
And as a chemist化学者,
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数年前 研究室のグループに
何にでも使える
00:27
one of the things I wanted to ask尋ねる my research研究 groupグループ a coupleカップル of years ago is,
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数年前、研究室のグループに
何にでも使える
00:31
could we make a really coolクール universalユニバーサル chemistry化学 setセット?
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化学実験キットが作れないか
課題を出しました
00:35
In essenceエッセンス, could we "appアプリ" chemistry化学?
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つまり化学のアプリ化が
可能かということです
00:40
Now what would this mean, and how would we do it?
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ではアプリ化の
意味と方法を見てみましょう
00:43
Well to start開始 to do this,
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始めるにあたって
00:45
we took取った a 3D printerプリンタ
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3Dプリンターを用意し
00:47
and we started開始した to print印刷する our beakersビーカー and our testテスト tubesチューブ on one side
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ビーカーや試験管などの
実験容器を印刷しました
00:51
and then print印刷する the molecule分子 at the same同じ time on the other side
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同時に別のプリンターで
分子を印刷し
00:55
and combine結合する them together一緒に in what we call reactionware反応装置.
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「反応容器」の中で
組み合わせました
00:58
And so by printing印刷 the vessel容器 and doing the chemistry化学 at the same同じ time,
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容器と分子の
同時印刷によって
01:03
we mayかもしれない start開始 to accessアクセス this universalユニバーサル toolkitツールキット of chemistry化学.
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化学アプリ開発の
可能性が生まれます
01:08
Now what could this mean?
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これは何を意味するか
01:09
Well if we can embed埋め込み biological生物学的 and chemical化学 networksネットワーク like a searchサーチ engineエンジン,
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生体 化学的ネットワークを
検索エンジンのように組み込めれば
01:15
so if you have a cell細胞 that's ill病気 that you need to cure治す
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病気の細胞を治したい時や
01:18
or bacteria細菌 that you want to kill殺します,
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細菌を殺したい時に
01:20
if you have this embedded埋め込み in your deviceデバイス
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手持ちの端末に
これが組み込まれていれば
01:22
at the same同じ time, and you do the chemistry化学,
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化学実験をしながら
01:24
you mayかもしれない be ableできる to make drugs薬物 in a new新しい way.
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全く新しい方法で
薬が作れるかもしれません
01:28
So how are we doing this in the lab研究室?
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これをラボでやるとしたら
01:30
Well it requires要求する softwareソフトウェア, it requires要求する hardwareハードウェア
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必要なのは
ソフトウェアとハードウェア
01:33
and it requires要求する chemical化学 inksインク.
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そして化学物質のインクです
01:36
And so the really coolクール bitビット is,
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これの凄い点は
01:37
the ideaアイディア is that we want to have a universalユニバーサル setセット of inksインク
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化学物質インクを一式用意し
01:40
that we put out with the printerプリンタ,
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プリンターにセットして
01:43
and you downloadダウンロード the blueprint青写真, the organicオーガニック chemistry化学 for that molecule分子
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分子の設計図を
ダウンロードして
01:47
and you make it in the deviceデバイス.
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端末上で作れるところです
01:50
And so you can make your molecule分子 in the printerプリンタ usingを使用して this softwareソフトウェア.
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アプリを使って分子を
作るわけです
01:55
So what could this mean?
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最終的には
01:58
Well, ultimately最終的に, it could mean that you could print印刷する your own自分の medicine医学.
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自分の薬を自分で印刷出来る
ようになります
02:03
And this is what we're doing in the lab研究室 at the moment瞬間.
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今はまだ研究段階ですが
02:05
But to take baby赤ちゃん stepsステップ to get there,
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目標に少しでも近付くために
02:06
first of all we want to look at drugドラッグ design設計 and production製造,
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まず 薬の構造や製薬方法
つまり-
02:09
or drugドラッグ discovery発見 and manufacturing製造.
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薬の開発や製造を考慮する
必要があります
02:12
Because if we can manufacture製造 it after we've私たちは discovered発見された it,
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薬の開発後に製造ができれば
02:15
we could deploy展開する it anywhereどこでも.
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どこにでも薬を
届けられるからです
02:17
You don't need to go to the chemist化学者 anymoreもう.
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薬局に行く必要はなくなります
02:19
We can print印刷する drugs薬物 at pointポイント of need.
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必要な場所で薬品を印刷し
02:22
We can downloadダウンロード new新しい diagnostics診断.
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新しい診断も
ダウンロードできます
02:24
Say a new新しい superスーパー bugバグ has emerged出現した.
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新種の薬剤耐性菌が現れても
すぐに検索して
02:26
You put it in your searchサーチ engineエンジン,
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新種の薬剤耐性細菌が現れても
すぐに検索して
02:28
and you create作成する the drugドラッグ to treat治療する the threat脅威.
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治療薬が作れます
02:31
So this allows許す you on-the-fly急いで molecular分子 assemblyアセンブリ.
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その場で分子を
構築できるのです
02:35
But perhapsおそらく for me the coreコア bitビット going into the future未来
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私が考えるこの研究の
将来性は
02:38
is this ideaアイディア of taking取る your own自分の stem cells細胞,
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人間の幹細胞を採取し
02:41
with your genes遺伝子 and your environment環境,
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遺伝子情報や環境と合わせて
02:43
and you print印刷する your own自分の personal個人的 medicine医学.
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自分専用の薬が
印刷できるという発想です
02:46
And if that doesn't seem思われる fanciful想像 enough十分な,
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もっと空想を広げるならば
02:48
where do you think we're going to go?
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さらにこの後に待つのは
02:50
Well, you're going to have your own自分の personal個人的 matter問題 fabricator製作者.
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個人専用の
物質構成装置かもしれません
02:55
Beamビーム me up, Scottyスコティ.
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「チャーリー、転送を頼む」
02:57
(Applause拍手)
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(拍手)

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ABOUT THE SPEAKER
Lee Cronin - Chemist
A professor of chemistry, nanoscience and chemical complexity, Lee Cronin and his research group investigate how chemistry can revolutionize modern technology and even create life.

Why you should listen

Lee Cronin's lab at the University of Glasgow does cutting-edge research into how complex chemical systems, created from non-biological building blocks, can have real-world applications with wide impact. At TEDGlobal 2012, Cronin shared some of the lab's latest work: creating a 3D printer for molecules. This device -- which has been prototyped -- can download plans for molecules and print them, in the same way that a 3D printer creates objects. In the future, Cronin says this technology could potentially be used to print medicine -- cheaply and wherever it is needed. As Cronin says: "What Apple did for music, I'd like to do for the discovery and distribution of prescription drugs."

At TEDGlobal 2011, Cronin shared his lab's bold plan to create life. At the moment, bacteria is the minimum unit of life -- the smallest chemical unit that can undergo evolution. But in Cronin's emerging field, he's thinking about forms of life that won't be biological. To explore this, and to try to understand how life itself originated from chemicals, Cronin and others are attempting to create truly artificial life from completely non-biological chemistries that mimic the behavior of natural cells. They call these chemical cells, or Chells. 

Cronin's research interests also encompass self-assembly and self-growing structures -- the better to assemble life at nanoscale. At the University of Glasgow, this work on crystal structures is producing a raft of papers from his research group. He says: "Basically one of my longstanding research goals is to understand how life emerged on planet Earth and re-create the process."

Read the papers referenced in his TEDGlobal 2102 talk:

Integrated 3D-printed reactionware for chemical synthesis and analysis, Nature Chemistry

Configurable 3D-Printed millifluidic and microfluidic ‘lab on a chip’ reactionware devices, Lab on a Chip

More profile about the speaker
Lee Cronin | Speaker | TED.com

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