ABOUT THE SPEAKER
Lee Cronin - Chemist
A professor of chemistry, nanoscience and chemical complexity, Lee Cronin and his research group investigate how chemistry can revolutionize modern technology and even create life.

Why you should listen

Lee Cronin's lab at the University of Glasgow does cutting-edge research into how complex chemical systems, created from non-biological building blocks, can have real-world applications with wide impact. At TEDGlobal 2012, Cronin shared some of the lab's latest work: creating a 3D printer for molecules. This device -- which has been prototyped -- can download plans for molecules and print them, in the same way that a 3D printer creates objects. In the future, Cronin says this technology could potentially be used to print medicine -- cheaply and wherever it is needed. As Cronin says: "What Apple did for music, I'd like to do for the discovery and distribution of prescription drugs."

At TEDGlobal 2011, Cronin shared his lab's bold plan to create life. At the moment, bacteria is the minimum unit of life -- the smallest chemical unit that can undergo evolution. But in Cronin's emerging field, he's thinking about forms of life that won't be biological. To explore this, and to try to understand how life itself originated from chemicals, Cronin and others are attempting to create truly artificial life from completely non-biological chemistries that mimic the behavior of natural cells. They call these chemical cells, or Chells. 

Cronin's research interests also encompass self-assembly and self-growing structures -- the better to assemble life at nanoscale. At the University of Glasgow, this work on crystal structures is producing a raft of papers from his research group. He says: "Basically one of my longstanding research goals is to understand how life emerged on planet Earth and re-create the process."

Read the papers referenced in his TEDGlobal 2102 talk:

Integrated 3D-printed reactionware for chemical synthesis and analysis, Nature Chemistry

Configurable 3D-Printed millifluidic and microfluidic ‘lab on a chip’ reactionware devices, Lab on a Chip

More profile about the speaker
Lee Cronin | Speaker | TED.com
TEDGlobal 2012

Lee Cronin: Print your own medicine

Ли Кронин: Дәріңізді принтерден басып шығарыңыз

Filmed:
1,045,687 views

Ли Кронин молекулаларды басып шығаратын 3D принтермен жұмыс істеуде. Ұзақ мерзімді қолдануға арналған бағдарлама жеке дәрі-дәрмектеріңізді химиялық сияларды қолдану арқылы басып шығарады.
- Chemist
A professor of chemistry, nanoscience and chemical complexity, Lee Cronin and his research group investigate how chemistry can revolutionize modern technology and even create life. Full bio

Double-click the English transcript below to play the video.

00:16
Organic chemists make molecules,
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Органик-химиктер үлкен молекулаларды
00:19
very complicated molecules,
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ревирсивтік инжинерия арқылы
00:21
by chopping up a big molecule into small molecules
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кішкентай бөліктерге майдалап
00:24
and reverse engineering.
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өте күрделі молекулаларды алады.
00:26
And as a chemist,
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Бірнеше жыл бұрын,
00:27
one of the things I wanted to ask my research group a couple of years ago is,
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химик ретінде зерттеушілеріме мынадай
сұрақ қойдым:
00:31
could we make a really cool universal chemistry set?
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жас химик үшін әмбебап құралдар жиынтығын
жасай аламыз ба?
00:35
In essence, could we "app" chemistry?
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Химиядан арнайы "қосымша"
жасай аламыз ба?
00:40
Now what would this mean, and how would we do it?
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Бұны қалай түсінеміз?
Қалай жүзеге асырамыз?
00:43
Well to start to do this,
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Сонымен, бұл үшін біз
00:45
we took a 3D printer
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3D принтер арқылы
00:47
and we started to print our beakers and our test tubes on one side
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ыдыстар мен түтікшелерді принтерден
шығара бастадық,
00:51
and then print the molecule at the same time on the other side
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дәл сол уақытта молекулаларды
өсіріп отырдық.
00:55
and combine them together in what we call reactionware.
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Кейін оларды бірге химиялық реакцияға
арналған ыдысқа салдық.
00:58
And so by printing the vessel and doing the chemistry at the same time,
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Осылайша, түтікшені жасап, химиялық
реакцияларды бір уақытта орындасақ,
01:03
we may start to access this universal toolkit of chemistry.
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химияның әмбебап құрылғыларына қол
жеткізе аламыз.
01:08
Now what could this mean?
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Бұның қажеті қанша?
01:09
Well if we can embed biological and chemical networks like a search engine,
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Егер биологикалық және химиялық желілерді
ерекше іздеу жүйелері сияқты енгізе алсақ,
01:15
so if you have a cell that's ill that you need to cure
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егер ауру жасушаны емдеу немесе бактерияны
жою керек болса
01:18
or bacteria that you want to kill,
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және осының барлығы
01:20
if you have this embedded in your device
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бір құрылғыда болса,
01:22
at the same time, and you do the chemistry,
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дәл сол уақытта химиялық реакцияларды
жасасаңыз,
01:24
you may be able to make drugs in a new way.
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онда жаңа әдіспен дәрі-дәрмек
жасай аласыз.
01:28
So how are we doing this in the lab?
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Біз бұны лабораториямызда қалай
істейміз?
01:30
Well it requires software, it requires hardware
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Ол үшін бағдарлама және құрылғы
01:33
and it requires chemical inks.
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және химиялық сия қажет.
01:36
And so the really cool bit is,
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Бірақ ең қызығы,
01:37
the idea is that we want to have a universal set of inks
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бізге қажеті әмбебап материалдар жиынтығы,
01:40
that we put out with the printer,
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яғни осы жиынтықты 3D принтерге саламыз,
01:43
and you download the blueprint, the organic chemistry for that molecule
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және жобаңыздың құрылымын,органикалық
молекуланың синтездеу әдісін жүктейсіз,
01:47
and you make it in the device.
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сөйтіп молекуланы осы құрылғыда жасайсыз.
01:50
And so you can make your molecule in the printer using this software.
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Осылайша молекулаңызды бағдарламаны
қолдану арқылы 3D принтерде жасайсыз.
01:55
So what could this mean?
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Бұдан не шықты?
01:58
Well, ultimately, it could mean that you could print your own medicine.
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Ақыр аяғында бұл жеке дәріңізді
принтерден өзіңіз шығарасыз деген сөз.
02:03
And this is what we're doing in the lab at the moment.
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Міне, қазір осы нәрсемен шұғылданудамыз.
02:05
But to take baby steps to get there,
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Болашақта бұл үшін ең кіші қадам,
02:06
first of all we want to look at drug design and production,
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бірінші дәрі-дәрмектерді жасау және
шығару,
02:09
or drug discovery and manufacturing.
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немесе жаңа дәрілерді ойлап тауып,
соларды шығару.
02:12
Because if we can manufacture it after we've discovered it,
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Себебі, егер ойлап тапқан дәрімізді
жасап шығара алсақ,
02:15
we could deploy it anywhere.
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онда оны кез келген жерде жүзеге
асыра аламыз
02:17
You don't need to go to the chemist anymore.
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Сізге бұдан әрі дәріханаға барудың
қажеті жоқ
02:19
We can print drugs at point of need.
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Қажет болған кезде дәріңізді басып
шығарасыз.
02:22
We can download new diagnostics.
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Жаңа диагноздарды жүктей аласыз.
02:24
Say a new super bug has emerged.
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Емі бар жаңа бактерия пайда болды делік.
02:26
You put it in your search engine,
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Бактерияны іздеу жүйесіне салып,
02:28
and you create the drug to treat the threat.
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соны жою үшін дәрі ойлап табасыз.
02:31
So this allows you on-the-fly molecular assembly.
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Яғни, бұл молекулаларды
жылдам құрастыруға мүмкіндік береді.
02:35
But perhaps for me the core bit going into the future
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Бірақ болашаққа көз жүгірте отырып,
мынаны елестетемін,
02:38
is this idea of taking your own stem cells,
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өзіңіздің жетілмеген жасушаларыңызды
геніңізбен және
02:41
with your genes and your environment,
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өмір сүру ортасымен бірге алып,
02:43
and you print your own personal medicine.
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дәл сізге сәйкес келетін жеке
дәрілеріңізді жасап шығару.
02:46
And if that doesn't seem fanciful enough,
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Егер бұл мүмкін дүние болса,
02:48
where do you think we're going to go?
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бұдан әрі қарай не болады деп ойлайсыздар?
02:50
Well, you're going to have your own personal matter fabricator.
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Мүмкін тірі ағзаны жасап шығаратын
жеке фабрикаңыз болатын шығар.
02:55
Beam me up, Scotty.
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Скотти, мені ауыстыр.
02:57
(Applause)
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(Қол соғу)
Translated by Nursultan Aubakirov
Reviewed by Askhat Yerkimbay

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ABOUT THE SPEAKER
Lee Cronin - Chemist
A professor of chemistry, nanoscience and chemical complexity, Lee Cronin and his research group investigate how chemistry can revolutionize modern technology and even create life.

Why you should listen

Lee Cronin's lab at the University of Glasgow does cutting-edge research into how complex chemical systems, created from non-biological building blocks, can have real-world applications with wide impact. At TEDGlobal 2012, Cronin shared some of the lab's latest work: creating a 3D printer for molecules. This device -- which has been prototyped -- can download plans for molecules and print them, in the same way that a 3D printer creates objects. In the future, Cronin says this technology could potentially be used to print medicine -- cheaply and wherever it is needed. As Cronin says: "What Apple did for music, I'd like to do for the discovery and distribution of prescription drugs."

At TEDGlobal 2011, Cronin shared his lab's bold plan to create life. At the moment, bacteria is the minimum unit of life -- the smallest chemical unit that can undergo evolution. But in Cronin's emerging field, he's thinking about forms of life that won't be biological. To explore this, and to try to understand how life itself originated from chemicals, Cronin and others are attempting to create truly artificial life from completely non-biological chemistries that mimic the behavior of natural cells. They call these chemical cells, or Chells. 

Cronin's research interests also encompass self-assembly and self-growing structures -- the better to assemble life at nanoscale. At the University of Glasgow, this work on crystal structures is producing a raft of papers from his research group. He says: "Basically one of my longstanding research goals is to understand how life emerged on planet Earth and re-create the process."

Read the papers referenced in his TEDGlobal 2102 talk:

Integrated 3D-printed reactionware for chemical synthesis and analysis, Nature Chemistry

Configurable 3D-Printed millifluidic and microfluidic ‘lab on a chip’ reactionware devices, Lab on a Chip

More profile about the speaker
Lee Cronin | Speaker | TED.com

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