ABOUT THE SPEAKER
Heribert Watzke - Food scientist
Heribert Watzke studies the brain in our gut -- and works to develop new kinds of food that will satisfy our bodies and minds.

Why you should listen

Heribert Watzke set up the department of food material science at Nestlé in Switzerland, pulling together many disciplines, including chemistry, nutrition and neuroscience, in pursuit of ever better foods. Watzke's background is in chemistry -- in the mid-'80s, he was part of a groundbreaking team at Syracuse working on splitting water into hydrogen and oxygen to create alternative energy -- before moving to materials science.

At Nestlé's lab, Watzke focuses on the most basic form of human energy: the chemistry of food. Research on food has previously focused on its sensory qualities -- taste, aroma, texture. But there is much more to know. How does food's biological structure determine its quality, its digestibility, its nutritional qualities? What's the science of turning a biological structure (for instance, a kernel of grain) into something humans can make into pure energy (for instance, a slice of bread)? His team has been looking recently at the impact of food structure on fat digestion, in support of the fight against obesity. How much fat is needed to feel full? And how can we most effectively communicate with the 100 million neurons in our gut?

More profile about the speaker
Heribert Watzke | Speaker | TED.com
TEDGlobal 2010

Heribert Watzke: The brain in your gut

Heribert Watzke:肠胃里的大脑

Filmed:
1,704,961 views

你是否知道在人的肠道里约有一亿神经元在发挥作用?食品科学家Heribert Watzke 将向我们揭秘我们肚子里的“隐藏的大脑”,以及它带给我们的惊奇感受。
- Food scientist
Heribert Watzke studies the brain in our gut -- and works to develop new kinds of food that will satisfy our bodies and minds. Full bio

Double-click the English transcript below to play the video.

00:16
This technology技术
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有一项技术
00:18
made制作 a very important重要 impact碰撞 on us.
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给我们带来了重大冲击。
00:20
It changed the way our history历史 developed发达.
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它改变了我们历史发展的道路。
00:24
But it's a technology技术 so pervasive无处不在,
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但是这项技术非常普遍,
00:26
so invisible无形,
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极不明显,
00:28
that we, for a long time,
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以至于我们在很长时间里,
00:30
forgot忘记 to take it into account帐户
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都忘了把它算入
00:33
when we talked about
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我们所说的
00:35
human人的 evolution演化.
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人类的演化中。
00:37
But we see the results结果 of this technology技术, still.
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但是,我们还是看到了这项技术的后果。
00:40
So let's make a little test测试.
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那么我们来做个小测验。
00:42
So everyone大家 of you turns to their neighbor邻居 please.
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现在请大家都转过去面对你身边的人。
00:46
Turn and face面对 your neighbors邻居.
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转过去面对旁边的。
00:48
Please, also on the balcony阳台.
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楼上的朋友也请照做。
00:51
Smile微笑. Smile微笑. Open打开 the mouths嘴巴.
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微笑,微笑。张嘴。
00:53
Smile微笑, friendly友善.
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微笑,友善点。
00:55
(Laughter笑声)
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(观众笑声)
00:57
Do you --
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你是否——
00:59
Do you see any Canine teeth?
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你能看到犬牙吗?
01:02
(Laughter笑声)
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(观众笑声)
01:04
Count计数 Dracula德古拉 teeth
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数数你旁边的人
01:07
in the mouths嘴巴 of your neighbors邻居?
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有多少吸血鬼尖牙?
01:09
Of course课程 not.
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当然没有。
01:11
Because our dental牙齿 anatomy解剖学
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因为我们的牙体解剖学
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is actually其实 made制作,
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并不是为了
01:16
not for tearing撕裂 down raw生的 meat from bones骨头
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从骨头上扯下生肉
01:19
or chewing咀嚼 fibrous纤维 leaves树叶 for hours小时.
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或花好几个小时咀嚼纤维质的树叶。
01:24
It is made制作 for a diet饮食
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它是为了进食那些
01:26
which哪一个 is soft柔软的, mushy糊状的,
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柔软的,糊状的东西
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which哪一个 is reduced减少 in fibers纤维,
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不含太多纤维,
01:32
which哪一个 is very easily容易 chewable咀嚼片
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非常容易咀嚼
01:34
and digestible易消化.
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和消化。
01:37
Sounds声音 like fast快速 food餐饮, doesn't it.
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听上去像快餐,是不是。
01:39
(Laughter笑声)
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(观众笑声)
01:41
It's for cooked food餐饮.
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它是为了进食烹制过的食品。
01:44
We carry携带 in our face面对 the proof证明
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我们的脸上就带着证据表明
01:47
that cooking烹饪,
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烹饪
01:49
food餐饮 transformation转型,
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也就是食物的转化
01:52
made制作 us what we are.
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造就我们今天的样子。
01:54
So I would suggest建议 that we change更改 how we classify分类 ourselves我们自己.
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所以我建议我们应该改变对自己的分类。
01:57
We talk about ourselves我们自己 as omnivores杂食动物.
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我们称自己是杂食动物。
02:00
I would say, we should call ourselves我们自己 coctivorscoctivors --
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我要说,我们应该称自己为煮食动物——
02:03
(Laughter笑声)
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(观众笑声)
02:05
from coquerecoquere, to cook厨师.
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烹饪,源自拉丁文coquere。
02:08
We are the animals动物
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我们这种动物
02:10
who eat cooked food餐饮.
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要吃烹饪的食物。
02:13
No, no, no, no. Better --
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不不不,更好的说法是——
02:15
to live生活 of cooked food餐饮.
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以烹煮过的食物为生。
02:17
So cooking烹饪 is a very important重要 technology技术.
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所以说烹饪是一项非常重要的技术。
02:19
It's technology技术.
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它的确是技术。
02:21
I don't know how you feel,
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我不知道你们怎么看,
02:23
but I like to cook厨师 for entertainment娱乐.
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但是我喜欢把烹饪当成娱乐。
02:25
And you need some design设计
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而且你需要一些构思
02:27
to be successful成功.
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才能成功。
02:29
So, cooking烹饪 is a very important重要 technology技术,
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那么,烹饪之所以是重要的技术,
02:32
because it allowed允许 us to acquire获得
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是因为它让我们获得了
02:35
what brought you all here:
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令我们演化到今天这个地步的东西:
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the big brain,
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大的脑子,
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this wonderful精彩 cerebral颅内 cortex皮质 we have.
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就是我们神奇的大脑皮层。
02:43
Because brains大脑 are expensive昂贵.
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因为脑子变大了,
02:46
Those have to pay工资 tuition学费 fees费用 know.
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所以我们现在必须要为此付费。
02:49
(Laughter笑声)
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(观众笑声)
02:51
But it's also, metabolically代谢 speaking请讲, expensive昂贵.
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但是同时,从新陈代谢角度看,这样的脑也很昂贵。
02:55
You now, our brain is two to three percent百分 of the body身体 mass,
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要知道,我们的大脑占身体总量的2-3%,
02:58
but actually其实 it uses使用 25 percent百分 of the total energy能源 we use.
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但事实上它要消耗我们所需的总能量的25%。
03:01
It's very expensive昂贵.
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这是很大的消耗。
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Where does the energy能源 come from. Of course课程, from food餐饮.
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那能量是从哪来的呢,当然是从食物来的。
03:06
If we eat raw生的 food餐饮,
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如果我们吃生的食物,
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we cannot不能 release发布 really the energy能源.
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就不能充分地释放能量。
03:12
So this ingenuity创造力 of our ancestors祖先,
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因此我们的祖先发挥聪明才智,
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to invent发明 this most marvelous奇妙 technology技术.
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发明了这个最不可思议的技术。
03:18
Invisible无形 -- everyone大家 of us does it every一切 day, so to speak说话.
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说它是无形的——就是说,我们每天都做饭。
03:22
Cooking烹饪 made制作 it possible可能
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烹饪使得
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that mutations突变,
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突变,
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natural自然 selections, our environment环境,
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自然选择,我们的环境,
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could develop发展 us.
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可以令我们发展演变。
03:32
So if we think about
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所以如果我们想想
03:34
this unleashing肆行 human人的 potential潜在,
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这一未释放的人类潜能,
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which哪一个 was possible可能 by cooking烹饪 and food餐饮,
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很可能来自烹饪和食物,
03:40
why do we talk so badly about food餐饮?
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那我们为什么还要说食物的坏话呢?
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Why is it always do and don'ts注意事项
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总是说吃这个,不能吃那个,
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and it's good for you, it's not good for you?
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这个对你有好处,那个对你没好处?
03:47
I think the good news新闻 for me
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我认为对我来说的好消息
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would be if we could go back
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就是如果我们回到开头
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and talk about the unleashing肆行,
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所说的未释放的,
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the continuation延续 of the unleashing肆行 of human人的 potential潜在.
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对释放人类的潜能的延续。
03:57
Now, cooking烹饪 allowed允许 also
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现在,烹饪也让我们
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that we became成为 a migrant农民 species种类.
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成为迁徙的物种。
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We walked out of Africa非洲 two times.
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我们两次走出非洲。
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We populated人口稠密 all the ecologies生态.
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我们在各种生态环境中繁衍。
04:07
If you can cook厨师, nothing can happen发生 to you,
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如果你能煮食,你就什么也不用怕,
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because whatever随你 you find,
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因为无论你找到什么,
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you will try to transform转变 it.
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你都会试图转化它们。
04:14
It keeps保持 also your brain working加工.
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它也让你开动脑筋想方设法。
04:17
Now the very easy简单 and simple简单 technology技术
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目前所发展出来的非常
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which哪一个 was developed发达
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简单易行的技术
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actually其实 runs运行 after this formula.
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事实上就是遵循这样的公式。
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Take something which哪一个 looks容貌 like food餐饮, transform转变 it,
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拿来一些看上去像食物的东西,转化它,
04:28
and it gives you a good, very easy简单, accessible无障碍 energy能源.
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它就提供给你好的,容易获取的能量。
04:31
This technology技术 affected受影响 two organs器官,
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这个技术影响到两个器官,
04:34
the brain and the gut肠道, which哪一个 it actually其实 affected受影响.
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大脑和肠胃,造成了实实在在的影响。
04:37
The brain could grow增长, but the gut肠道 actually其实 shrunk压缩.
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脑子变大了,但是肠胃却缩小了。
04:40
Okay, it's not obvious明显 to be honest诚实.
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好吧,老实说这点在我这里并不太明显。
04:42
(Laughter笑声)
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(观众笑声)
04:45
But it shrunk压缩 to 60 percent百分
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但是它缩小到从前的60%
04:47
of primate灵长类动物 gut肠道
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这是相对于我的体量的
04:49
of my body身体 mass.
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灵长目动物的肠道而言。
04:51
So because of having cooked food餐饮,
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因为有了熟食,
04:54
it's easier更轻松 to digest消化.
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就更容易消化。
04:57
Now having a large brain, as you know,
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正如大家所知,有一个较大的脑子,
05:00
is a big advantage优点,
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是一个很大的优势,
05:02
because you can actually其实 influence影响 your environment环境.
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因为你能确实地影响你的环境。
05:05
You can influence影响 your own拥有 technologies技术 you have invented发明.
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你可以影响你自己已经发明的厨艺。
05:07
You can continue继续 to innovate创新 and invent发明.
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你可以继续发明创造。
05:09
Now the big brain did this also with cooking烹饪.
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现在这个大个的脑子也要在烹饪方面发挥创意。
05:12
But how did it actually其实 run this show显示?
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但具体是如何实现的呢?
05:15
How did it actually其实 interfere干扰?
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事实上它是如何介入的呢?
05:17
What kind of criteria标准 did it use?
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它采用怎样的条件?
05:20
And this is actually其实 taste味道 reward奖励 and energy能源.
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而且确实会带来更好的味道和能量。
05:24
You know we have up to five tastes口味,
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你知道我们最多能有五种味觉,
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three of them sustain支持 us.
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其中三种是我们维持生命需要的。
05:29
Sweet -- energy能源.
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甜——能量。
05:31
Umami鲜味 -- this is a meaty肉香 taste味道.
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鲜——这是肉类的味道。
05:33
You need proteins蛋白质 for muscles肌肉, recovery复苏.
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你需要蛋白质生成肌肉,以及恢复健康。
05:37
Salty,
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咸,
05:39
because you need salt, otherwise除此以外 your electric电动 body身体 will not work.
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因为你需要盐份,否则你身体的电解质无法运作。
05:42
And two tastes口味 which哪一个 protect保护 you --
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而另外两种味道是保护你的——
05:45
bitter and sour,
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苦和酸,
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which哪一个 are against反对
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它们代表了
05:50
poisonous有毒 and rotten material材料.
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有毒和腐坏的物质。
05:53
But of course课程, they are hard-wired硬连线
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当然,这些都是与生俱来的,
05:55
but we use them still in a sophisticated复杂的 way.
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但是我们还是可以通过精密的方法来利用它们。
05:57
Think about bittersweet苦乐参半 chocolate巧克力;
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想想又苦又甜的巧克力。
05:59
or think about the acidity酸度
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或是酸奶的酸味
06:01
of yogurt酸奶 -- wonderful精彩 --
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很奇妙地
06:03
mixed with strawberry草莓 fruits水果.
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混合了草莓。
06:05
So we can make mixtures混合物 of all this kind of thing
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之所以我们可以混合所有这些东西
06:08
because we know
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是因为我们知道
06:11
that, in cooking烹饪, we can transform转变 it
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通过烹调,我们可以将它们转化
06:13
to the form形成.
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成形。
06:15
Reward奖励: this is a more complex复杂
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奖赏:这是一个更为复杂
06:18
and especially特别 integrative综合
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和特别一体化
06:21
form形成 of our brain
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的形式存在于我们的大脑中
06:23
with various各个 different不同 elements分子 --
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其中包含了各种各样的因素——
06:26
the external外部 states状态, our internal内部 states状态,
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外部环境,我们的内部状态,
06:28
how do we feel, and so on are put together一起.
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我们如何感知以及其它所有这些都放在一起。
06:31
And something which哪一个 maybe you don't like
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而且有些东西你可能未必喜欢,
06:33
but you are so hungry饥饿 that you really will be satisfied满意 to eat.
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但是你太饿了所以你也可以很满意地吃下去。
06:36
So satisfaction满意 was a very important重要 part部分.
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所以满足感是一个非常重要的部分。
06:39
And as I say, energy能源 was necessary必要.
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而且正如我说的,能量也是必须的。
06:41
Now how did the gut肠道 actually其实
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那么事实上肠胃是如何
06:43
participate参加 in this development发展?
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参与到这一发展当中呢?
06:46
And the gut肠道 is a silent无声 voice语音 --
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肠胃能在无声中发言。
06:49
it's going more for feelings情怀.
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它更强调感觉。
06:51
I use the euphemism婉辞 digestive消化 comfort安慰 --
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我用一种委婉的说法就是消化舒适。
06:55
actually其实 -- it's a digestive消化 discomfort不舒服,
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事实上它是消化不适,
06:58
which哪一个 the gut肠道 is concerned关心 with.
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而这是肠胃所关心的。
07:01
If you get a stomach ache疼痛, if you get a little bit bloated,
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如果你胃痛,如果你有点腹胀,
07:04
was not the right food餐饮, was not the right cooking烹饪 manipulation操作
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要不是食物不对,要不就是烹饪的方式不对。
07:07
or maybe other things went wrong错误.
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或者是别的地方出了问题。
07:09
So my story故事 is a tale故事 of two brains大脑,
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我要讲的是两个大脑的故事,
07:12
because it might威力 surprise you,
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因为你可能会很惊讶,
07:14
our gut肠道 has a full-fledged羽翼丰满 brain.
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我们的肠胃有一个训练有素的大脑。
07:17
All the managers经理 in the room房间 say,
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在座的所有管理层都会说,
07:19
"You don't tell me something new, because we know, gut肠道 feeling感觉.
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“你不用说这是什么新东西,因为我们知道,肚子里有数。
07:21
This is what we are using运用."
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我们一直都是这么用的。”
07:23
(Laughter笑声)
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(观众笑声)
07:25
And actually其实 you use it and it's actually其实 useful有用.
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而事实上,你的确是在使用它,它真的很有用。
07:27
Because our gut肠道 is connected连接的 to our emotional情绪化 limbic边缘 system系统,
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因为我们的肠胃与我们的脑缘系统相连。
07:30
they do speak说话 with each other
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它们的确相互沟通
07:32
and make decisions决定.
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并作出决定。
07:35
But what it means手段
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但是在这里
07:37
to have a brain there
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拥有一个大脑意味着
07:39
is that, not only the big brain
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不仅是那个大个的脑子
07:42
has to talk with the food餐饮,
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要与食物交谈,
07:45
the food餐饮 has to talk with the brain,
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食物本身也要和大脑说话,
07:48
because we have to learn学习 actually其实
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因为我们必须学习
07:51
how to talk to the brains大脑.
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如何真的和这些大脑交谈。
07:53
Now if there's a gut肠道 brain,
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如果肠胃里真有一个大脑,
07:55
we should also learn学习 to talk with this brain.
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我们也必须学习和这个脑沟通。
07:57
Now 150 years年份 ago,
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距今150年前,
07:59
anatomists解剖学家 described描述 very, very carefully小心 --
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解剖学家做了非常非常仔细的描述——
08:02
here is a model模型 of a wall of a gut肠道.
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这里是一个胃肠壁的模型——
08:05
I took the three elements分子 --
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我取其中的三个成员——
08:07
stomach, small intestine and colon结肠.
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胃,小肠和结肠。
08:10
And within this structure结构体,
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在这套结构中,
08:12
you see these two pinkish粉红色 layers,
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你可以看到这两层粉红色的东西,
08:14
which哪一个 are actually其实 the muscle肌肉.
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这实际上是肌肉。
08:16
And between之间 this muscle肌肉, they found发现 nervous紧张 tissues组织,
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在这些肌肉之间,他们发现了神经组织,
08:18
a lot of nervous紧张 tissues组织,
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大量的神经组织,
08:20
which哪一个 penetrate穿透 actually其实 the muscle肌肉 --
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它们渗透在整层肌肉中,
08:22
penetrate穿透 the submucosa粘膜下层,
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进入粘膜下层,
08:24
where you have all the elements分子 for the immune免疫的 system系统.
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那里都是免疫系统。
08:26
The gut肠道 is actually其实 the largest最大 immune免疫的 system系统,
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肠胃事实上是最大的免疫系统,
08:28
defending卫冕 your body身体.
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保护着你的身体。
08:30
It penetrates渗透 the mucosa粘膜.
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它渗入到粘膜。
08:32
This is the layer which哪一个 actually其实 touches触摸 the food餐饮 you are swallowing吞咽
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这层真正接触到你吞咽下去
08:35
and you digest消化,
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以及要消化的食物,
08:37
which哪一个 is actually其实 the lumen流明.
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这就是内腔。
08:39
Now if you think about the gut肠道,
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现在如果你想想我们的肠胃,
08:41
the gut肠道 is -- if you could stretch伸展 it --
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如果你将其伸展开,
08:43
40 meters long,
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它有40米长,
08:45
the length长度 of a tennis网球 court法庭.
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相当于一个网球场的长度。
08:47
If we could unroll it,
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如果我们把它摊开,
08:49
get out all the folds褶皱 and so on,
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把所有褶皱都摊平,
08:52
it would have 400 sq平方. meters of surface表面.
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表面积将有400平方米。
08:55
And now this brain takes care关心 over this,
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现在这个脑子在管理着这一切,
08:58
to move移动 it with the muscles肌肉 and to do defend保卫 the surface表面
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调动肌肉使之运动,保护表面,
09:01
and, of course课程, digest消化 our food餐饮 we cook厨师.
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当然,还要消化我们所煮的食物。
09:04
So if we give you a specification规范,
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如果要给你们一个更具体的认识,
09:07
this brain, which哪一个 is autonomous自主性,
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那么这个独立自主的大脑,
09:09
have 500 million百万 nerve神经 cells细胞,
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有5亿个神经细胞,
09:11
100 million百万 neurons神经元 --
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一亿个神经元——
09:13
so around the size尺寸 of a cat brain,
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这差不多是一只猫的大脑,
09:16
so there sleeps睡觉 a little cat --
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所以我们的肚子里正睡着只小猫——
09:19
thinks for itself本身,
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自己在那里盘算着,
09:21
optimizes公司优化 whatever随你 it digests摘要.
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如何最大化地利用所消化的食物。
09:24
It has 20 different不同 neuron神经元 types类型.
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它有20种不同的神经元。
09:27
It's got the same相同 diversity多样 you find actually其实 in a pig brain,
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和你能在猪脑子里发现的神经元种类一样多,
09:29
where you have 100 billion十亿 neurons神经元.
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而猪有一千亿个神经元。
09:32
It has autonomous自主性 organized有组织的 microcircuits微电路,
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它具有自发组成的微电路,
09:35
has these programs程式 which哪一个 run.
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还有各种程序在运转。
09:37
It senses感官 the food餐饮; it knows知道 exactly究竟 what to do.
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它感受到食物,知道应该干什么。
09:40
It senses感官 it by chemical化学 means手段
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它通过化学方式感受到食物,
09:42
and very importantly重要的 by mechanical机械 means手段,
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更重要的是机械的方式,
09:45
because it has to move移动 the food餐饮 --
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因为它必须要移动这些食物,
09:47
it has to mix混合 all the various各个 elements分子
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它必须把我们消化吸收所需的所有不同元素
09:49
which哪一个 we need for digestion消化.
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都搅和在一起。
09:51
This control控制 of muscle肌肉 is very, very important重要,
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对肌肉的控制是非常非常重要的,
09:54
because, you know, there can be reflexes反射.
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因为,要知道这里存在着反射作用。
09:56
If you don't like a food餐饮, especially特别 if you're a child儿童, you gag插科打诨.
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如果你不喜欢某类食物,尤其当你还是小孩时,你会作呕。
09:59
It's this brain which哪一个 makes品牌 this reflex反射.
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正是这个大脑令你作出这个反射动作的。
10:01
And then finally最后,
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最后还有,
10:03
it controls控制 also the secretion分泌 of this molecular分子 machinery机械,
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它还控制着分子结构上的分泌作用,
10:06
which哪一个 actually其实 digests摘要 the food餐饮 we cook厨师.
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这才是对我们所煮食物的真正消化。
10:09
Now how do the two brains大脑 work with each other?
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那么这两个大脑是如何相互合作的呢?
10:12
I took here a model模型 from robotics机器人 --
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在这里我使用了一个机器人学的模型。
10:15
it's called the Subsumption涵摄 Architecture建筑.
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叫做包容结构。
10:18
What it means手段 is that we have a layered分层 control控制 system系统.
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也就是说我们所拥有的是一个分层的控制系统。
10:21
The lower降低 layer, our gut肠道 brain,
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较低层次是我们的肠胃大脑。
10:23
has its own拥有 goals目标 -- digestion消化 defense防御 --
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它有着自己的目标——消化和防御——
10:26
and we have the higher更高 brain
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我们还有一个较高级的大脑,
10:28
with the goal目标 of integration积分
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其目标是整合
10:30
and generating发电 behaviors行为.
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和引起行动。
10:32
Now both look -- and this is the blue蓝色 arrows箭头 --
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现在这两个大脑都看到——就是这里的蓝色箭头——
10:35
both look to the same相同 food餐饮, which哪一个 is in the lumen流明
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它们都看到同样的食物在内腔里,
10:38
and in the area of your intestine.
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以及在小肠部分。
10:40
The big brain integrates整合 signals信号,
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大个的大脑整合所有信号,
10:42
which哪一个 come from the running赛跑 programs程式
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这些信号来自较低层大脑
10:44
of the lower降低 brain,
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所运转的程序,
10:46
But subsumption包容 means手段
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但包容意味着,
10:48
that the higher更高 brain can interfere干扰 with the lower降低.
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高层大脑能够干涉低层次的大脑。
10:51
It can replace更换,
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它可以替换,
10:53
or it can inhibit抑制 actually其实, signals信号.
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或甚至阻止那些信号。
10:56
So if we take two types类型 of signals信号 --
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因此如果我们收到两种信号——
10:58
a hunger饥饿 signal信号 for example.
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比如一个是饥饿的信号——
11:00
If you have an empty stomach,
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如果你的胃是空的,
11:02
your stomach produces产生 a hormone激素 called ghrelin生长素.
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它就会分泌出一种荷尔蒙叫饥饿激素。
11:04
It's a very big signal信号;
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这是一个非常强烈的信号。
11:06
it's sent发送 to the brain says,
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它向你的大脑说,
11:08
"Go and eat."
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“去吃!”
11:10
You have stop signals信号 --
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你还收到停止的信号。
11:12
we have up to eight stop signals信号.
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我们最多能收到8个停止的信号。
11:14
At least最小 in my case案件,
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至少在我这里,
11:16
they are not listened听了 to.
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这些信号都不管用。
11:18
(Laughter笑声)
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(观众笑声)
11:20
So what happens发生
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那么会怎样?
11:22
if the big brain in the integration积分
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如果大的大脑从整体上
11:25
overrides覆盖 the signal信号?
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压制了这个信号?
11:27
So if you override覆盖 the hunger饥饿 signal信号,
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如果你压制了饥饿的信号,
11:29
you can have a disorder紊乱, which哪一个 is called anorexia厌食症.
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你就会造成失调,叫做神经性食欲缺乏。
11:32
Despite尽管 generating发电
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尽管出现了
11:34
a healthy健康 hunger饥饿 signal信号,
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一个正常的饥饿信号,
11:36
the big brain ignores忽略 it
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但你的大个大脑却无视它,
11:38
and activates激活 different不同 programs程式 in the gut肠道.
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并在肠胃里激活不同的程序。
11:41
The more usual通常 case案件
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更常见的情况
11:43
is overeating暴饮暴食.
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是过度进食。
11:46
It actually其实 takes the signal信号
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大脑确实收到了信号
11:49
and changes变化 it,
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并改变了它,
11:51
and we continue继续,
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然后我们就继续吃,
11:53
even [though虽然] our eight signals信号 would say, "Stop, enough足够.
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甚至我们的八种信号都在说,“停!够了。
11:56
We have transferred转入 enough足够 energy能源."
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我们已经转化了足够的能量。”
11:58
Now the interesting有趣 thing is that,
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这时有趣的地方就在于,
12:00
along沿 this lower降低 layer -- this gut肠道 --
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在肠胃这个较低的层次上,
12:02
the signal信号 becomes stronger and stronger
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这个信号会变得越来越强
12:05
if undigested未消化, but digestible易消化, material材料
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如果我们吃了一些尚未吸收但是又可以吸收
12:08
could penetrate穿透.
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的食物。
12:10
This we found发现 from bariatric减肥 surgery手术.
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这种情况出现在缩减消化道的减肥手术中。
12:14
That then the signal信号 would be very, very high.
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这种情况下饥饿信号会非常非常强烈。
12:17
So now back to the cooking烹饪 question
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现在回到烹饪的问题。
12:20
and back to the design设计.
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回到设计菜式的问题。
12:22
We have learned学到了 to talk to the big brain --
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我们已经学习了要和大的大脑交谈——
12:25
taste味道 and reward奖励, as you know.
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你知道,就是味道和奖赏。
12:27
Now what would be the language语言
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那么我们该用什么语言
12:29
we have to talk to the gut肠道 brain
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和肠胃里的大脑交谈?
12:31
that its signals信号 are so strong强大
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它发出的信号强烈到
12:33
that the big brain cannot不能 ignore忽视 it?
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让大的大脑都不能无视?
12:36
Then we would generate生成 something
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这样我们就能得到
12:38
all of us would like to have --
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我们大家都想要的东西——
12:40
a balance平衡 between之间 the hunger饥饿
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处于饥饿和满足之间的
12:42
and the satiation饱食.
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平衡。
12:45
Now I give you, from our research研究, a very short claim要求.
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通过我们的研究,我可以告诉你们一个小结论。
12:48
This is fat脂肪 digestion消化.
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这就是脂肪消化。
12:50
You have on your left
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在你的左边
12:52
an olive橄榄 oil droplet水滴,
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是一滴橄榄油,
12:54
and this olive橄榄 oil droplet水滴 gets得到 attacked袭击 by enzymes.
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这种橄榄油会被酶类攻击。
12:57
This is an in vitro体外 experiment实验.
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这是在试管中进行的实验。
12:59
It's very difficult to work in the intestine.
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因为很难在肠道里做实验。
13:02
Now everyone大家 would expect期望
308
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现在每个人都知道
13:04
that when the degradation降解 of the oil happens发生,
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当油滴开始降解时,
13:06
when the constituents成分 are liberated解放,
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当其中的组成成分被释放出来时,
13:08
they disappear消失, they go away
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它们会消失,不见掉,
13:10
because they [were] absorbed吸收.
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因为它们被吸收了。
13:12
Actually其实, what happens发生 is that a very intricate错综复杂 structure结构体 appears出现.
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但真正出现的是一个非常复杂的结构。
13:15
And I hope希望 you can see
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我希望你们可以看到
13:17
that there are some ring-like环状的 structures结构 in the middle中间 image图片,
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在中间这张图里有一些环状的结构,
13:19
which哪一个 is water.
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那就是水。
13:21
This whole整个 system系统 generates生成 a huge巨大 surface表面
317
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这整个系统会生成巨大的表面积
13:24
to allow允许 more enzymes
318
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可以让更多的酶类
13:26
to attack攻击 the remaining其余 oil.
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去攻击那些剩余的油脂。
13:28
And finally最后, on your right side,
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而最后,在你的右边,
13:30
you see a bubbly香槟酒,
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你会看到出现了一个泡泡状的,
13:32
cell-like细胞样 structure结构体 appearing出现,
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细胞一样的结构,
13:34
from which哪一个 the body身体 will absorb吸收 the fat脂肪.
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身体会从中吸收脂肪。
13:38
Now if we could take this language语言 --
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现在如果我们能使这种语言——
13:40
and this is a language语言 of structures结构 --
325
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而这是一种结构语言——
13:43
and make it longer-lasting寿命更长,
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维持更长时间,
13:46
that it can go through通过
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让它维持在
13:48
the passage通道 of the intestine,
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整个肠道内,
13:51
it would generate生成 stronger signals信号.
329
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它就会产生更强烈的信号。
13:55
So our research研究 --
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因此我们的研究——
13:57
and I think the research研究 also at the universities高校 --
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而且我想大学里也有类似的研究——
13:59
are now fixing定影 on these points
332
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就是在修正这些地方
14:01
to say: how can we actually其实 --
333
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也就是说,我们如何能真正的——
14:03
and this might威力 sound声音 trivial不重要的 now to you --
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这对你们来说可能觉得有点无意义——
14:05
how can we change更改 cooking烹饪?
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我们如何能改变烹饪的技术?
14:07
How can we cook厨师
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我们该如何做饭
14:09
that we have this language语言 developed发达?
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当我们发展出这门语言以后?
14:12
So what we have actually其实, it's not an omnivore's杂食动物的 dilemma困境.
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所以我们真正面对的,不是一个杂食动物的两难处境。
14:15
We have a coctivor'scoctivor的 opportunity机会,
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而是一个煮食动物的机遇,
14:18
because we have learned学到了 over the last two million百万 years年份
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因为在过去的2百万年里,我们已经学习了
14:21
which哪一个 taste味道 and reward奖励 --
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什么是好吃的和有营养的——
14:24
quite相当 sophisticated复杂的 to cook厨师 --
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学习了非常复杂的烹调技术——
14:26
to please ourselves我们自己, to satisfy满足 ourselves我们自己.
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来让自己高兴,满足。
14:28
If we add the matrix矩阵,
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如果我们再加上更精细的内容,
14:30
if we add the structure结构体 language语言, which哪一个 we have to learn学习,
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如果我们加上结构性的语言,这是我们必须了解的,
14:33
when we learn学习 it, then we can put it back;
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当我们了解了这个语言,我们就可以把它用回去,
14:35
and around energy能源,
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在能量之间,
14:37
we could generate生成 a balance平衡,
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我们就能产生一个平衡,
14:39
which哪一个 comes out
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而这将来自
14:41
from our really primordial原始 operation手术: cooking烹饪.
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我们最为原始的行为:煮食。
14:45
So, to make cooking烹饪 really
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因此,真的把烹饪当成
14:48
a very important重要 element元件,
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一个非常重要的因素来看,
14:50
I would say even philosophers哲学家 have to change更改
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我会说就连哲学家们都必须改变看法
14:52
and have to finally最后 recognize认识
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并且最终不得不承认
14:54
that cooking烹饪 is what made制作 us.
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是烹饪造就了我们。
14:57
So I would say, coquocoquo ergoERGO sum:
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因此我要说:coquo ergo sum(拉丁语)
15:00
I cook厨师, therefore因此 I am.
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我煮故我在。
15:02
Thank you very much.
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非常感谢大家!
15:04
(Applause掌声)
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(观众鼓掌)
Translated by yuanyuan liang
Reviewed by Xu (Jessica) Jiang

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ABOUT THE SPEAKER
Heribert Watzke - Food scientist
Heribert Watzke studies the brain in our gut -- and works to develop new kinds of food that will satisfy our bodies and minds.

Why you should listen

Heribert Watzke set up the department of food material science at Nestlé in Switzerland, pulling together many disciplines, including chemistry, nutrition and neuroscience, in pursuit of ever better foods. Watzke's background is in chemistry -- in the mid-'80s, he was part of a groundbreaking team at Syracuse working on splitting water into hydrogen and oxygen to create alternative energy -- before moving to materials science.

At Nestlé's lab, Watzke focuses on the most basic form of human energy: the chemistry of food. Research on food has previously focused on its sensory qualities -- taste, aroma, texture. But there is much more to know. How does food's biological structure determine its quality, its digestibility, its nutritional qualities? What's the science of turning a biological structure (for instance, a kernel of grain) into something humans can make into pure energy (for instance, a slice of bread)? His team has been looking recently at the impact of food structure on fat digestion, in support of the fight against obesity. How much fat is needed to feel full? And how can we most effectively communicate with the 100 million neurons in our gut?

More profile about the speaker
Heribert Watzke | Speaker | TED.com

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