Sandrine Thuret: You can grow new brain cells. Here's how
Sandrine Thuret: Pódenche medrar novas neuronas. Aquí tes como.
Sandrine Thuret studies the way adult brains create new nerve cells in the hippocampus -- a brain area involved in memory and mood. Full bio
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que nos medren novas neuronas?
about that question,
sobre este asunto,
investigación moi novidosa.
to one of my colleagues, Robert,
colega meu, Robert,
they are cured of their cancer
que están curados dun cancro
that makes sense.
that stops the cancer cells multiplying
proliferación das células cancerosas
being generated in their brain."
de neuronas no cerebro.
like I was crazy and said,
como se eu tolease e dixo,
neuronas novas."
"Well actually, we do."
"Medránnos, si".
that we call neurogenesis.
neuroxénese.
he was not taught what we know now --
non se ensinaba o que sabemos agora:
can generate new nerve cells.
novas células nerviosas.
being the good doctor that he is,
científico que é
a little bit better.
parts of the brain
excitantes do cerebro
in the center of the brain.
for very long,
memory, mood and emotion.
a memoria, o estado de ánimo e a emoción.
have learned more recently
só desde hai pouco
structures of the adult brain
do cerebro adulto
in an adult mouse brain.
nun cerebro de rato adulto.
from the Karolinska Institutet,
do Instituto Karolinska,
700 new neurons per day
700 neuronas novas ao día
of neurons we have.
de neuronas que temos.
we were born with in that structure
desta estrutura coas que nacimos
and what are their functions?
novas neuronas e que funcións cumpren?
for learning and memory.
para a aprendizaxe e a memoria.
of the adult brain
do cerebro adulto
for spatial recognition --
no caso do recoñecemento espacial,
your way in the city.
o noso camiño pola cidade.
non só para a capacidade de memoria,
for memory capacity,
to add time to our memory
tempo á nosa memoria
very similar memories, like:
memorias moi parecidas, a saber:
every day in the same area,
todos os días na mesma zona,
to my colleague Robert
para o meu colega Robert
on neurogenesis and depression.
sobre neuroxénese e depresión.
a lower level of neurogenesis.
baixo nivel de neuroxénese.
of these newborn neurons,
destas novas neuronas,
the symptoms of depression,
de depresión
between neurogenesis and depression.
entre neuroxénese e depresión.
just block neurogenesis,
a neuroxénese,
of the antidepressant.
do antidepresivo.
were suffering from depression
pacientes sufrían de depresión
newborn neurons from being generated.
a xeneración de novas neuronas.
to generate new neurons
para xerar novas neuronas
we have enough evidence
que temos evidencia de abondo
is a target of choice
é unha clara alternativa
memory formation or mood,
de memorias e o estado anímico,
associated with aging,
asociado ao avellentamento,
of behaviors and activities,
de condutas e actividades,
they will increase neurogenesis
que aumentan a neuroxénese
of these new neurons.
destas novas neuronas.
of new neurons in the hippocampus.
de novas neuronas no hipocampo.
the production of new neurons.
a produción de novas neuronas.
buscar o equilibrio.
leading to sleep deprivation.
leve á privaciónd de sono.
will decrease as we get older,
ao facerse vello,
Rusty Gage from the Salk Institute,
Rusty Gage, do Instituto Salk,
can have an impact
pode ter un impacto
of the hippocampus of a mouse
do hipocampo dun rato
na súa gaiola.
are actually newborn neurons-to-be.
son novas neuronas formándose.
of the hippocampus of a mouse
do hipocampo dun rato
the new neurons-to-be.
novas neuronas en formación.
but that's not all.
pero isto non é todo.
in the hippocampus.
no hipocampo.
to have efficacy.
demostrado eficaces.
to point a few out to you:
will increase neurogenesis.
por cento aumenta a neuroxénese.
spacing the time between your meals --
espaciar o tempo entre comidas --
in dark chocolate or blueberries,
negro ou nas arandeiras,
of these new neurons.
in high saturated fat
en graxas saturadas
on neurogenesis.
will decrease neurogenesis.
diminúe a neuroxénese.
contained in red wine,
the survival of these new neurons.
a supervivencia destas novas neuronas.
"neurogenesis-neutral" drink.
de bebida 'neutral' para a neuroxénese.
unha última cousa,
let me point out the last one --
with food textures,
as texturas das comidas,
soft diet impairs neurogenesis,
blandas prexudican á neuroxénese,
mastication -- chewing -- or crunchy food.
masticar, ou os alimentos crocantes.
at the cellular level,
mirar a nivel celular,
to human participants,
administrado a humanos,
the diet modulates memory and mood
modula a memoria e o estado de ánimo
as it modulates neurogenesis,
modula a neuroxénese,
will improve memory capacity,
mellora a capacidade de memoria,
symptoms of depression --
exacerba os síntomas da depresión,
which increase neurogenesis,
que incrementan a neuroxénese,
the symptoms of depression.
os síntomas depresivos.
e o estado de ánimo,
of the new neurons in the hippocampus.
de novas neuronas no hipocampo.
of the food, when you eat it
cándo os comes
interested in neurogenesis --
interesados na neuroxénese --
the function of these new neurons,
a función destas novas neuronas,
and their production.
supervivencia e a súa produción.
the neurogenesis of Robert's patients.
a neuroxénese dos pacientes de Robert.
of your neurogenesis.
Estupenda investigación, Sandrine.
Fantastic research, Sandrine.
de cambiame a vida.
in the running thing.
about aerobic exercise,
if it's just the running itself,
se é correr en sí,
will increase the production --
que aumente a produción
unha roda de exercicio na oficina?
a running wheel in my office?
ABOUT THE SPEAKER
Sandrine Thuret - Neural stem cell researcherSandrine Thuret studies the way adult brains create new nerve cells in the hippocampus -- a brain area involved in memory and mood.
Why you should listen
In her lab at King's College London, Sandrine Thuret studies adult neurogenesis -- the process by which adult brains create new nerve cells. (Until the 1990s, we didn't even know they did this!)
Thuret's work focuses on the hippocampus, the area of the brain that is related to memory, and her work asks two big questions: How can we help our healthy brains create new nerve cells throughout our lives, through diet and behavior changes? And how can we study the effects of diseases such as depression and Alzheimer's on our brains' ability to grow?
Sandrine Thuret | Speaker | TED.com