ABOUT THE SPEAKER
Juan Enriquez - Futurist
Juan Enriquez thinks and writes about the profound changes that genomics and other life sciences will bring in business, technology, politics and society.

Why you should listen

A broad thinker who studies the intersections of these fields, Enriquez has a talent for bridging disciplines to build a coherent look ahead. He is the managing director of Excel Venture Management, a life sciences VC firm. He recently published (with Steve Gullans) Evolving Ourselves: How Unnatural Selection and Nonrandom Mutation Are Shaping Life on Earth. The book describes a world where humans increasingly shape their environment, themselves and other species.

Enriquez is a member of the board of Synthetic Genomics, which recently introduced the smallest synthetic living cell. Called “JCVI-syn 3.0,” it has 473 genes (about half the previous smallest cell). The organism would die if one of the genes is removed. In other words, this is the minimum genetic instruction set for a living organism.

More profile about the speaker
Juan Enriquez | Speaker | TED.com
TEDxSummit

Juan Enriquez: Will our kids be a different species?

Juan Enriquez: 我們的後代將會是不同的物種嗎?

Filmed:
2,006,663 views

在人類的進化史中, 多個不同的人種曾經共同生存過。我們現在還處在不斷進化中嗎? 在 TEDxSummit 這裏,Juan Enriquez 將帶我們穿越時空,從遠古到現代,向我們展示科技是如何找到證據來揭示:進化也許正在迅速進行中。
- Futurist
Juan Enriquez thinks and writes about the profound changes that genomics and other life sciences will bring in business, technology, politics and society. Full bio

Double-click the English transcript below to play the video.

00:16
All right. So, like all good stories故事,
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好吧,就像那些童話故事一樣,
00:18
this starts啟動 a long, long time ago
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這個故事要從很久很久以前講起,
00:20
when there was basically基本上 nothing.
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當時宇宙基本上是一片空白
00:22
So here is a complete完成 picture圖片 of the universe宇宙
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這張圖片展現的就是
00:24
about 14-odd-奇 billion十億 years年份 ago.
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140多億年前的整個宇宙
00:28
All energy能源 is concentrated集中 into a single point of energy能源.
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所有的能量都集中在一個能量點
00:31
For some reason原因 it explodes爆炸,
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由於某種原因它爆炸了
00:32
and you begin開始 to get these things.
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宇宙裏開始出現這些東西
00:35
So you're now about 14 billion十億 years年份 into this.
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它們已經存在了140多億年
00:37
And these things expand擴大 and expand擴大 and expand擴大
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而且在不斷地擴大、擴大、擴大
00:39
into these giant巨人 galaxies星系,
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形成了這些巨大的星系
00:41
and you get trillions萬億 of them.
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數量達到幾萬億
00:42
And within these galaxies星系
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在這些星系裏
00:44
you get these enormous巨大 dust灰塵 clouds.
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出現大量的塵埃雲
00:47
And I want you to pay工資 particular特定 attention注意
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請大家注意看
00:48
to the three little prongs插腳
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圖片中心的
00:50
in the center中央 of this picture圖片.
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這三個小突起
00:52
If you take a close-up特寫 of those,
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如果給它們來個特寫的話
00:53
they look like this.
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它們看上去就是這個樣子
00:55
And what you're looking at is columns of dust灰塵
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大家所看到的是塵埃柱
00:58
where there's so much dust灰塵 --
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其中滿是塵埃
01:00
by the way, the scale規模 of this is a trillion vertical垂直 miles英里 --
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順便提一句,它的規模有一萬億英里
01:04
and what's happening事件 is there's so much dust灰塵,
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這些大量的塵埃
01:07
it comes together一起 and it fuses熔斷器
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相互聚集,熔合
01:09
and ignites點燃 a thermonuclear熱核 reaction反應.
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引發了熱核反應
01:12
And so what you're watching觀看
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現在大家所看到的
01:13
is the birth分娩 of stars明星.
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便是恒星的誕生
01:15
These are stars明星 being存在 born天生 out of here.
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恒星就是在這裏產生的
01:17
When enough足夠 stars明星 come out,
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當恒星的數量足夠多時
01:19
they create創建 a galaxy星系.
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它們形成了一個星系
01:21
This one happens發生 to be a particularly尤其 important重要 galaxy星系,
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而這個星系恰巧是至關重要的
01:24
because you are here.
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因為我們大家就生活在這裏
01:27
(Laughter笑聲)
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(笑聲)
01:28
And as you take a close-up特寫 of this galaxy星系,
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仔細觀察這個星系
01:30
you find a relatively相對 normal正常,
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我們會發現一個比較平凡
01:32
not particularly尤其 interesting有趣 star.
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並不引人注目的恒星
01:34
By the way, you're now about two-thirds三分之二 of the way into this story故事.
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順便提一句,這個故事已經講了三分之二了
01:38
So this star doesn't even appear出現
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而這顆恒星
01:40
until直到 about two-thirds三分之二 of the way into this story故事.
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卻直到現在才出現
01:43
And then what happens發生
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現在的情況是
01:44
is there's enough足夠 dust灰塵 left over
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由於剩餘的塵埃
01:46
that it doesn't ignite點燃 into a star,
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不足以引發熱核反應形成恒星
01:48
it becomes a planet行星.
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於是它成為了行星
01:50
And this is about a little over four billion十億 years年份 ago.
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這大約發生在40億年前
01:54
And soon不久 thereafter其後
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不久之後
01:56
there's enough足夠 material材料 left over
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由於擁有足夠的剩餘原料
01:58
that you get a primordial原始 soup,
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便有了一鍋「原湯」
02:02
and that creates創建 life.
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生命便從這裏起源
02:04
And life starts啟動 to expand擴大 and expand擴大 and expand擴大,
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而且不斷地擴大、擴大、再擴大
02:08
until直到 it goes kaput過時的.
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直到它塵歸塵,土歸土
02:10
(Laughter笑聲)
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(笑聲)
02:13
Now the really strange奇怪 thing
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有件事情非常的奇怪
02:15
is life goes kaput過時的, not once一旦, not twice兩次,
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生命滅絕了不止一次、兩次
02:18
but five times.
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而是五次
02:20
So almost幾乎 all life on Earth地球
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幾乎地球上的所有生命
02:22
is wiped out about five times.
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都被消滅了五次
02:24
And as you're thinking思維 about that,
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正如大家所想的一樣
02:26
what happens發生 is you get more and more complexity複雜,
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新生命變得越來越複雜
02:28
more and more stuff東東
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越來越多的材質
02:30
to build建立 new things with.
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包含在裏面
02:34
And we don't appear出現
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而我們人類
02:35
until直到 about 99.96 percent百分 of the time into this story故事,
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直到這個故事的99.96%才出現
02:41
just to put ourselves我們自己 and our ancestors祖先 in perspective透視.
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以便我們正確看待自己和我們的祖先
02:44
So within that context上下文, there's two theories理論 of the case案件
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在這個背景下有兩種理論
02:48
as to why we're all here.
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來解釋人類為什麼存在
02:50
The first theory理論 of the case案件
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第一種理論
02:51
is that's all she wrote.
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這都是她寫下來的
02:55
Under that theory理論,
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按照這種理論
02:56
we are the be-all待所有 and end-all最終所有
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人類是造物主
02:58
of all creation創建.
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最重要的創造
03:00
And the reason原因 for trillions萬億 of galaxies星系,
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所以數萬億的星系
03:02
sextillionssextillions of planets行星,
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以及數量眾多的行星存在的原因
03:04
is to create創建 something that looks容貌 like that
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是為了創造這樣…
03:09
and something that looks容貌 like that.
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和那樣的生命體
03:13
And that's the purpose目的 of the universe宇宙;
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這就是宇宙存在的目的
03:14
and then it flat-lines平線,
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然後它就開始走平穩路線
03:16
it doesn't get any better.
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沒有再進一步提高水準
03:17
(Laughter笑聲)
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(笑聲)
03:21
The only question you might威力 want to ask yourself你自己 is,
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大家可能想問自己
03:24
could that be just mildly溫和 arrogant傲慢?
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這樣的解釋是不是有些妄自尊大呢?
03:29
And if it is --
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如果是這樣的話
03:31
and particularly尤其 given特定 the fact事實 that we came來了 very close to extinction滅絕.
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特別是鑒於人類曾經接近滅絕的事實
03:37
There were only about 2,000 of our species種類 left.
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當時只剩下大約二千人
03:40
A few少數 more weeks without rain,
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要是再有幾個星期不下雨
03:42
we would have never seen看到 any of these.
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我們就再也見不到這些名人了
03:45
(Laughter笑聲)
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(笑聲)
03:52
(Applause掌聲)
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(掌聲)
03:56
So maybe you have to think about a second第二 theory理論
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因此我們也許不得不考慮另一種理論
03:59
if the first one isn't good enough足夠.
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如果第一種解釋不通的話
04:02
Second第二 theory理論 is: Could we upgrade升級?
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第二種理論是:我們能不能「升級」?
04:04
(Laughter笑聲)
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(笑聲)
04:07
Well, why would one ask a question like that?
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怎麼會有人問出這樣的問題呢?
04:10
Because there have been at least最小 29 upgrades升級 so far
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因為目前為止一經發現
04:13
of humanoids類人型機器人.
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人類已至少「升級」了29次
04:15
So it turns out that we have upgraded升級.
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結果表明我們確實「升級」了
04:18
We've我們已經 upgraded升級 time and again and again.
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人類一次一次地「升級」
04:20
And it turns out that we keep discovering發現 upgrades升級.
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而且我們還在不斷地發現新的「升級」的證據
04:22
We found發現 this one last year.
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這是去年發現的
04:25
We found發現 another另一個 one last month.
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我們上個月還發現了一個
04:27
And as you're thinking思維 about this,
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現在大家都在思考這個理論
04:29
you might威力 also ask the question:
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可能會產生這個疑問
04:32
So why a single human人的 species種類?
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為什麼僅僅是人類呢?
04:35
Wouldn't豈不 it be really odd
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如果我們在非洲、亞洲、南極洲
04:36
if you went to Africa非洲 and Asia亞洲 and Antarctica南極洲
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發現同一種鳥類
04:40
and found發現 exactly究竟 the same相同 bird --
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會不會是件很稀奇的事情?
04:43
particularly尤其 given特定 that we co-existed並存 at the same相同 time
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特別是考慮到我們曾經
04:47
with at least最小 eight other versions版本 of humanoid人形
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和至少其他八類人種
04:49
at the same相同 time on this planet行星?
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在這個星球上共同存在過
04:52
So the normal正常 state of affairs事務
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智人是唯一存在的人種這種說法
04:54
is not to have just a Homo智人 sapiens智人;
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不是自然界的普遍法則
04:56
the normal正常 state of affairs事務
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自然界的普遍法則是
04:57
is to have various各個 versions版本 of humans人類 walking步行 around.
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各種不同種類的人
05:01
And if that is the normal正常 state of affairs事務,
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如果自然界的法則是這樣
05:04
then you might威力 ask yourself你自己,
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那麼你可能要問自己
05:06
all right, so if we want to create創建 something else其他,
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如果我們想創造出其他的人種
05:08
how big does a mutation突變 have to be?
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要產生多大的變異才可以?
05:11
Well Svante斯萬特· Paabo帕博 has the answer回答.
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Svante Paabo 給出了答案
05:14
The difference區別 between之間 humans人類 and Neanderthal尼安德特人
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人類和尼安德塔人(遠古的人種)
05:17
is 0.004 percent百分 of gene基因 code.
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基因上只有0.004%的差別
05:20
That's how big the difference區別 is
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一個人種和另一個人種
05:22
one species種類 to another另一個.
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就是這麼一點差別
05:24
This explains說明 most contemporary現代的 political政治 debates辯論.
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這就解釋了現在多數的政治糾紛
05:28
(Laughter笑聲)
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(笑聲)
05:30
But as you're thinking思維 about this,
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大家仔細想一想
05:33
one of the interesting有趣 things
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一件非常有意思的事情
05:35
is how small these mutations突變 are and where they take place地點.
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這些變異有多麼微妙?又是在哪發生的?
05:38
Difference區別 human人的/Neanderthal尼安德特人
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人類和尼安德塔人的不同在於
05:40
is sperm精子 and testis睾丸,
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精子與睪丸
05:41
smell and skin皮膚.
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氣味與皮膚
05:43
And those are the specific具體 genes基因
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這些特殊的基因
05:44
that differ不同 from one to the other.
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產生了人與人的區別
05:47
So very small changes變化 can have a big impact碰撞.
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因此一點小小的變化就能產生很大的影響
05:50
And as you're thinking思維 about this,
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大家想想
05:52
we're continuing繼續 to mutate變異.
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我們一直在變異
05:54
So about 10,000 years年份 ago by the Black黑色 Sea,
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在大約一萬年前的黑海
05:57
we had one mutation突變 in one gene基因
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人類的一個基因產生了變異
05:59
which哪一個 led to blue藍色 eyes眼睛.
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因此出現了藍色的眼睛
06:02
And this is continuing繼續 and continuing繼續 and continuing繼續.
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這樣的變異一直持續著、持續著
06:05
And as it continues繼續,
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與此同時
06:07
one of the things that's going to happen發生 this year
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一件大事將在今年發生
06:09
is we're going to discover發現 the first 10,000 human人的 genomes基因組,
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我們將發現前一萬個人類基因組
06:12
because it's gotten得到 cheap低廉 enough足夠 to do the gene基因 sequencing測序.
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這得益於基因序列研究已經不那麼昂貴了
06:15
And when we find these,
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當我們發現這些基因之後
06:17
we may可能 find differences分歧.
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我們會找到一些不同以往的理論
06:19
And by the way, this is not a debate辯論 that we're ready準備 for,
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順便說一句,我們沒有準備好爭論這個問題
06:22
because we have really misused誤用 the science科學 in this.
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因為我們在這個問題上誤用了科學
06:26
In the 1920s, we thought there were major重大的 differences分歧 between之間 people.
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在1920年代,我們曾認為不同人之間的基因有很大差別
06:29
That was partly部分地 based基於 on Francis弗朗西斯 Galton's高爾頓的 work.
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這是部分基於法蘭西斯•高爾頓的研究
06:33
He was Darwin's達爾文 cousin表姐.
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他是達爾文的表弟
06:35
But the U.S., the Carnegie卡內基 Institute研究所,
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在美國,卡內基研究所
06:38
Stanford斯坦福, American美國 Neurological神經 Association協會
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史丹佛,美國神經病學協會
06:40
took this really far.
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把這種研究進一步深入
06:42
That got exported出口 and was really misused誤用.
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進而傳播到其他地方被錯誤地使用
06:46
In fact事實, it led to some absolutely絕對 horrendous可怕的
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事實上它對人類平等待遇
06:48
treatment治療 of human人的 beings眾生.
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造成了非常可怕的後果
06:50
So since以來 the 1940s, we've我們已經 been saying there are no differences分歧,
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所以自1940年代,我們一直在說我們沒有差別
06:53
we're all identical相同.
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大家都是一樣的
06:54
We're going to know at year end結束 if that is true真正.
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今年年底我們將知道這是不是真的
06:58
And as we think about that,
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現在大家想想
06:59
we're actually其實 beginning開始 to find things
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事實上,我們開始發現一些東西
07:01
like, do you have an ACE高手 gene基因?
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比如,你有ACE基因嗎?
07:04
Why would that matter?
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它有什麼重要的呢?
07:06
Because nobody's沒有人是 ever climbed爬上 an 8,000-meter-儀表 peak without oxygen
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因為沒有一個不帶氧氣能爬上8000米高的山峰的人
07:10
that doesn't have an ACE高手 gene基因.
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是不攜帶ACE基因的
07:13
And if you want to get more specific具體,
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如果你想瞭解得更具體
07:15
how about a 577R genotype基因型?
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來看看577R基因型怎麼樣?
07:18
Well it turns out that every一切 male Olympic奧林匹克 power功率 athelete痤瘡各類 ever tested測試
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結果表明每個接受檢測的奧運男運動員
07:23
carries攜帶 at least最小 one of these variants變種.
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都攜帶這種基因型的至少一種變體
07:26
If that is true真正,
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如果這是真的
07:28
it leads引線 to some very complicated複雜 questions問題
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那麼就有一些很複雜的問題
07:30
for the London倫敦 Olympics奧運會.
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留給倫敦奧運會
07:32
Three options選項:
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三個問題
07:33
Do you want the Olympics奧運會 to be a showcase櫥窗
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我們希望奧運會成為
07:36
for really hardworking用功 mutants突變體?
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刻苦訓練的、擁有突變基因的運動員展示的舞臺嗎?
07:39
(Laughter笑聲)
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(笑聲)
07:40
Option選項 number two:
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第二
07:43
Why don't we play it like golf高爾夫球 or sailing帆船?
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為什麼我們不像高爾夫球或者帆船運動那樣比賽呢?
07:47
Because you have one and you don't have one,
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因為你有這個基因、而你沒有
07:49
I'll give you a tenth第十 of a second第二 head start開始.
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我會讓你搶佔十分之一秒的優勢
07:53
Version number three:
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第三
07:54
Because this is a naturally自然 occurring發生 gene基因
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因為這是自然形成的基因
07:56
and you've got it and you didn't pick the right parents父母,
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你有幸的到了這個基因、而你卻投錯了胎
07:59
you get the right to upgrade升級.
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所以你可以晉級
08:03
Three different不同 options選項.
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三種不同的選擇
08:05
If these differences分歧 are the difference區別
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如果這些差別就是
08:06
between之間 an Olympic奧林匹克 medal勳章 and a non-Olympic非奧運 medal勳章.
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奧運獎牌和非奧運獎牌的差別
08:10
And it turns out that as we discover發現 these things,
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就像我們所發現的一樣
08:12
we human人的 beings眾生 really like to change更改
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人類非常願意改變
08:16
how we look, how we act法案,
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自己的容貌、 行為方式
08:17
what our bodies身體 do.
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以及身體狀況
08:19
And we had about 10.2 million百萬 plastic塑料 surgeries手術 in the United聯合的 States狀態,
190
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在美國有過大約1020萬例整形外科手術
08:23
except that with the technologies技術 that are coming未來 online線上 today今天,
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除了那些即將上線的新技術
08:27
today's今天的 corrections更正, deletions缺失,
192
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現如今修復、去除
08:29
augmentations擴充 and enhancements增強
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豐胸、美容
08:31
are going to seem似乎 like child's孩子的 play.
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看起來如同兒戲一般
08:34
You already已經 saw the work by Tony托尼 Atala阿塔拉 on TEDTED,
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我們在TED上看過 Tony Atala 的研究
08:38
but this ability能力 to start開始 filling填充
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這種填充東西的技術
08:42
things like inkjet噴墨 cartridges墨盒 with cells細胞
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就像是裝滿細胞的噴墨水匣一樣
08:45
are allowing允許 us to print打印 skin皮膚, organs器官
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讓我們能隨心所欲的 “列印” 皮膚、器官
08:49
and a whole整個 series系列 of other body身體 parts部分.
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以及一系列身體部位
08:52
And as these technologies技術 go forward前鋒,
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隨著這些技術的進步
08:54
you keep seeing眼看 this, you keep seeing眼看 this, you keep seeing眼看 things --
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我們會不斷看到這個,我們會不斷看到這個,我們會不斷看到新東西
08:58
2000, human人的 genome基因組 sequence序列 --
202
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2000年,人類基因組序列
09:00
and it seems似乎 like nothing's什麼是 happening事件,
203
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事情就好像是直到該發生的時候
09:04
until直到 it does.
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才會發生
09:07
And we may可能 just be in some of these weeks.
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我們也許就處在發生重大變革的這幾個星期內
09:11
And as you're thinking思維 about
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我們知道
09:12
these two guys sequencing測序 a human人的 genome基因組 in 2000
207
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3451
這兩位在2000年研究人類基因序列
09:16
and the Public上市 Project項目 sequencing測序 the human人的 genome基因組 in 2000,
208
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還有2000年的人類基因序列公開專案
09:19
then you don't hear a lot,
209
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3164
然後就沒有太多這方面的消息了
09:23
until直到 you hear about an experiment實驗 last year in China中國,
210
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3984
直到大家聽說在中國的一次實驗
09:27
where they take skin皮膚 cells細胞 from this mouse老鼠,
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他們從老鼠身上取出皮膚細胞
09:31
put four chemicals化學製品 on it,
212
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在上面注入四種化學藥劑
09:32
turn those skin皮膚 cells細胞 into stem cells細胞,
213
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把皮膚細胞轉變成幹細胞
09:36
let the stem cells細胞 grow增長
214
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讓這些幹細胞生長
09:37
and create創建 a full充分 copy複製 of that mouse老鼠.
215
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然後完全“複製”了那只老鼠
09:40
That's a big deal合同.
216
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這是很了不起的
09:44
Because in essence本質
217
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1016
因為從本質上講
09:45
what it means手段 is you can take a cell細胞,
218
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2148
這就意味著我們可以拿一個
09:47
which哪一個 is a pluripotent多能 stem cell細胞,
219
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2286
多能幹細胞
09:49
which哪一個 is like a skier滑雪者 at the top最佳 of a mountain,
220
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2684
它們就像山頂上的滑雪者
09:52
and those two skiers滑雪者 become成為 two pluripotent多能 stem cells細胞,
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兩個滑雪者就是兩個多功能幹細胞
09:56
four, eight, 16,
222
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1782
分裂成四個、八個、十六個
09:57
and then it gets得到 so crowded
223
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1668
然後就變得越來越擁擠
09:59
after 16 divisions
224
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1800
十六次分裂之後
10:01
that those cells細胞 have to differentiate區分.
225
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2502
這些細胞不得不變異
10:03
So they go down one side of the mountain,
226
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1433
所以他們從山的一面走下來
10:05
they go down another另一個.
227
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他們從另一面走下來
10:06
And as they pick that,
228
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1534
當他們選擇了這條路
10:08
these become成為 bone,
229
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2250
就變成了骨骼
10:10
and then they pick another另一個 road and these become成為 platelets血小板,
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那些選擇另一條路的變成了血小板
10:13
and these become成為 macrophages巨噬細胞,
231
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這些變成了巨噬細胞
10:15
and these become成為 T cells細胞.
232
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這些變成了T細胞
10:16
But it's really hard, once一旦 you ski滑雪 down,
233
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1952
可是一旦你滑下去
10:18
to get back up.
234
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1523
就很難再回頭了
10:20
Unless除非, of course課程, if you have a ski滑雪 lift電梯.
235
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當然啦,除非你有滑雪纜車
10:25
And what those four chemicals化學製品 do
236
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那四種化學藥劑的作用
10:27
is they take any cell細胞
237
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就是載著細胞
10:30
and take it way back up the mountain
238
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1932
回到山頂上
10:31
so it can become成為 any body身體 part部分.
239
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2033
讓它們具有變成身體任何部分的能力
10:33
And as you think of that,
240
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1728
正如大家所想的
10:35
what it means手段 is potentially可能
241
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1980
這就意味著
10:37
you can rebuild重建 a full充分 copy複製
242
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我們很有可能
10:39
of any organism生物
243
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1867
只用一個細胞
10:41
out of any one of its cells細胞.
244
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2586
複製任何器官
10:44
That turns out to be a big deal合同
245
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這是一個重大突破
10:46
because now you can take, not just mouse老鼠 cells細胞,
246
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2566
因為現在不僅是老鼠細胞
10:49
but you can human人的 skin皮膚 cells細胞
247
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我們可以把人類的皮膚細胞
10:51
and turn them into human人的 stem cells細胞.
248
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變成幹細胞
10:55
And then what they did in October十月
249
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3198
就在10月份
10:58
is they took skin皮膚 cells細胞, turned轉身 them into stem cells細胞
250
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3400
他們把皮膚細胞變成了幹細胞
11:01
and began開始 to turn them into liver cells細胞.
251
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3673
然後開始把它們變成肝臟細胞
11:05
So in theory理論,
252
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1044
所以理論上講
11:06
you could grow增長 any organ器官 from any one of your cells細胞.
253
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我們的任何一個細胞可以被培養成任何一個器官
11:11
Here's這裡的 a second第二 experiment實驗:
254
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1718
這是第二個實驗
11:13
If you could photocopy複印件 your body身體,
255
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3133
如果我們能給身體做個影印件
11:16
maybe you also want to take your mind心神.
256
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3052
或許也想給思想做一個
11:19
And one of the things you saw at TEDTED
257
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1565
大約一年半之前
11:21
about a year and a half ago
258
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1250
大家在TED
11:22
was this guy.
259
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1435
見過這個傢伙
11:24
And he gave a wonderful精彩 technical技術 talk.
260
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2600
他做了很精彩的技術演講
11:26
He's a professor教授 at MITMIT.
261
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1599
他是MIT的教授
11:28
But in essence本質 what he said
262
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1916
但本質上,他說的是
11:30
is you can take retroviruses逆轉錄病毒,
263
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1700
利用逆轉錄病毒
11:31
which哪一個 get inside brain cells細胞 of mice老鼠.
264
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2800
讓它們進入老鼠的腦細胞
11:34
You can tag標籤 them with proteins蛋白質
265
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2440
並用蛋白質標記它們
11:37
that light up when you light them.
266
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2094
這種蛋白質在被照亮時會發光
11:39
And you can map地圖 the exact精確 pathways途徑
267
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3716
當老鼠看到、感覺到、觸摸到東西
11:42
when a mouse老鼠 sees看到, feels感覺, touches觸摸,
268
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3483
回憶、戀愛的時候
11:46
remembers記得, loves.
269
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2183
我們能夠準確描繪出腦部活動路徑
11:48
And then you can take a fiber纖維 optic視神經 cable電纜
270
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2373
我們可以用光纖電纜
11:50
and light up some of the same相同 things.
271
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3819
點亮這些相同的東西
11:54
And by the way, as you do this,
272
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1832
我們在做這件事情的時候
11:56
you can image圖片 it in two colors顏色,
273
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2017
可以把它們製成兩種顏色
11:58
which哪一個 means手段 you can download下載 this information信息
274
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2399
這意味著我們可以把這些資訊
12:01
as binary二進制 code directly into a computer電腦.
275
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4740
像二進位碼一樣下載到電腦上
12:05
So what's the bottom底部 line on that?
276
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2473
這件事情本質上是什麼呢?
12:08
Well it's not completely全然 inconceivable不可思議
277
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2200
不難想像
12:10
that someday日後 you'll你會 be able能夠 to download下載 your own擁有 memories回憶,
278
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4495
也許有一天我們可以把自己的記憶
12:14
maybe into a new body身體.
279
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2387
下載到一個新的軀體裏
12:17
And maybe you can upload上載 other people's人們 memories回憶 as well.
280
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5085
或許也可以把別人的記憶載入到自己身上
12:22
And this might威力 have just one or two
281
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2514
估計這只會引起一兩個
12:24
small ethical合乎道德的, political政治, moral道德 implications啟示.
282
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3520
小小的政治上、道德上的問題
12:28
(Laughter笑聲)
283
732528
1531
(笑聲)
12:29
Just a thought.
284
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2991
隨便想想而已
12:32
Here's這裡的 the kind of questions問題
285
737050
1528
有一些問題
12:34
that are becoming變得 interesting有趣 questions問題
286
738578
1980
正在逐漸引起
12:36
for philosophers哲學家, for governing治理 people,
287
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2484
哲學家、管理者
12:38
for economists經濟學家, for scientists科學家們.
288
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3366
經濟學家、科學家的興趣
12:42
Because these technologies技術 are moving移動 really quickly很快.
289
746408
3284
因為這些技術傳播的非常快
12:45
And as you think about it,
290
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1500
大家意猶未盡
12:47
let me close with an example of the brain.
291
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3082
讓我舉個關於大腦的例子來結束今天的演講
12:50
The first place地點 where you would expect期望
292
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1683
如果我們最先期待
12:51
to see enormous巨大 evolutionary發展的 pressure壓力 today今天,
293
755957
3051
看到一個器官的顯著進化
12:54
both because of the inputs輸入,
294
759008
2265
不僅因為
12:57
which哪一個 are becoming變得 massive大規模的,
295
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1552
在這方面越來越多的研究投入
12:58
and because of the plasticity可塑性 of the organ器官,
296
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1782
而且由於其具有可塑性
13:00
is the brain.
297
764607
2534
那麼這個器官就是大腦
13:03
Do we have any evidence證據 that that is happening事件?
298
767141
3318
有證據證明這種進化正在發生嗎?
13:06
Well let's take a look at something like autism自閉症 incidence發生率 per thousand.
299
770459
4731
讓我們來看看每千人中自閉症發生概率
13:11
Here's這裡的 what it looks容貌 like in 2000.
300
775190
2502
這是2000年的狀況
13:13
Here's這裡的 what it looks容貌 like in 2002,
301
777692
2082
這是2002年的狀況
13:15
2006, 2008.
302
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4618
2006,2008
13:20
Here's這裡的 the increase增加 in less than a decade.
303
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4082
這是不到10年的時間裏所增加的數量
13:24
And we still don't know why this is happening事件.
304
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4417
我們直到現在也不知道為什麼是這樣
13:28
What we do know is, potentially可能,
305
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2485
我們所知道的是,
13:31
the brain is reacting反應 in
306
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2032
大腦潛在的以一種
13:33
a hyperactive多動, hyper-plastic超塑 way,
307
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2134
極度活躍的方式在反應
13:35
and creating創建 individuals個人 that are like this.
308
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2950
並創造出同樣活躍的個體
13:38
And this is only one of the conditions條件 that's out there.
309
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2757
這僅僅是其中存在的一種情況
13:41
You've also got people with who are extraordinarily異常 smart聰明,
310
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3540
我們還見過非常聰明的人
13:44
people who can remember記得 everything they've他們已經 seen看到 in their lives生活,
311
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2397
過目不忘的人
13:47
people who've誰一直 got synesthesia聯覺,
312
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1385
能產生牽連感覺的人
13:48
people who've誰一直 got schizophrenia精神分裂症.
313
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1331
精神分裂的人
13:49
You've got all kinds of stuff東東 going on out there,
314
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2534
我們見過各種各樣的情況
13:52
and we still don't understand理解
315
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1218
但現在依舊不明白
13:53
how and why this is happening事件.
316
817654
2233
為什麼這一切發會生,是又如何發生的
13:55
But one question you might威力 want to ask is,
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大家可能要問
13:58
are we seeing眼看 a rapid快速 evolution演化 of the brain
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大腦是在高速進化嗎?
14:01
and of how we process處理 data數據?
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我們是怎樣處理資料的?
14:02
Because when you think of how much data's數據的 coming未來 into our brains大腦,
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當涉及到有多少資料進入大腦時
14:05
we're trying to take in as much data數據 in a day
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我們現在一天內要接收的資訊
14:09
as people used to take in in a lifetime一生.
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相當於過去人們一輩子所接收到的資訊
14:12
And as you're thinking思維 about this,
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現在大家考慮一下這個問題
14:14
there's four theories理論 as to why this might威力 be going on,
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這裏有四種理論來解釋這種現象
14:16
plus a whole整個 series系列 of others其他.
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以及一系列其他的理論
14:18
I don't have a good answer回答.
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我給不出一個漂亮的答案
14:19
There really needs需求 to be more research研究 on this.
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在這方面確實還需要更多的研究
14:23
One option選項 is the fast快速 food餐飲 fetish物神.
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一個選擇是速食迷戀
14:25
There's beginning開始 to be some evidence證據
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開始有證據表明
14:28
that obesity肥胖 and diet飲食
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肥胖和飲食
14:30
have something to do
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與基因改造
14:32
with gene基因 modifications修改,
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有關
14:33
which哪一個 may可能 or may可能 not have an impact碰撞
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但不能確定
14:36
on how the brain of an infant嬰兒 works作品.
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它對嬰兒大腦運作的影響
14:39
A second第二 option選項 is the sexy性感的 geek極客 option選項.
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第二個選擇是“性感的書呆子”
14:43
These conditions條件 are highly高度 rare罕見.
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這種情況確實很少見
14:47
(Laughter笑聲)
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(笑聲)
14:51
(Applause掌聲)
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(掌聲)
14:56
But what's beginning開始 to happen發生
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現在的情況是
14:57
is because these geeks怪才 are all getting得到 together一起,
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這些書呆子們聚在一起
15:00
because they are highly高度 qualified合格 for computer電腦 programming程序設計
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他們有很高的電腦編程技能
15:03
and it is highly高度 remunerated報酬,
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酬勞很高
15:05
as well as other very detail-oriented注重細節 tasks任務,
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還有從事其他注重細節的工作
15:08
that they are concentrating集中 geographically地理
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他們集中到一起
15:11
and finding發現 like-minded志同道合 mates隊友.
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尋找志同道合的人
15:14
So this is the assortative選型 mating交配 hypothesis假設
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所以這就是選擇性交配假設
15:17
of these genes基因 reinforcing加強 one another另一個
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這些基因在體系中
15:20
in these structures結構.
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互相增援
15:22
The third第三, is this too much information信息?
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第三,資訊是不是太多了?
15:25
We're trying to process處理 so much stuff東東
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我們的大腦試圖處理太多的資訊
15:27
that some people get synesthetic聯覺
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以至於有些人產生了牽連感覺
15:29
and just have huge巨大 pipes管道 that remember記得 everything.
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他們擁有巨大的管道來記住所有事情
15:32
Other people get hyper-sensitive超敏感 to the amount of information信息.
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有一些人對大量資訊過分敏感
15:34
Other people react應對 with various各個 psychological心理 conditions條件
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有一些人對資訊做出反應時
15:38
or reactions反應 to this information信息.
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伴隨著各種各樣心理上的狀況和反應
15:40
Or maybe it's chemicals化學製品.
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也許是化學反應
15:43
But when you see an increase增加
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如果發現
15:44
of that order訂購 of magnitude大小 in a condition條件,
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某種情況的數量大幅度提升
15:47
either you're not measuring測量 it right
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不是測量不準確
15:48
or there's something going on very quickly很快,
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就是有什麼事情正在迅速發展
15:51
and it may可能 be evolution演化 in real真實 time.
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說不定就是在進化
15:55
Here's這裡的 the bottom底部 line.
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歸根結底
15:57
What I think we are doing
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我認為作為一個物種
15:59
is we're transitioning過渡 as a species種類.
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我們正在轉化
16:01
And I didn't think this when Steve史蒂夫 GullansGullans and I started開始 writing寫作 together一起.
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當Steve Gullans和我一起寫作的時候我並不這樣認為
16:07
I think we're transitioning過渡 into Homo智人 evolutisevolutis
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我覺得我們正在向演化人轉化
16:09
that, for better or worse更差,
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無論是好是壞
16:11
is not just a hominid原始人 that's conscious意識 of his or her environment環境,
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這都不僅僅是一個只對周圍環境有意識的人種
16:15
it's a hominid原始人 that's beginning開始 to directly and deliberately故意
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而是一个直接的、有意的
16:18
control控制 the evolution演化 of its own擁有 species種類,
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想要控制
16:21
of bacteria, of plants植物, of animals動物.
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自己的种族、細菌、植物、乃至動物进化的人种
16:25
And I think that's such這樣 an order訂購 of magnitude大小 change更改
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我認為,如果我們的孫輩或重孫輩
16:28
that your grandkids孫子 or your great-grandkids偉大,孫子
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與我們是完全不同的物種
16:31
may可能 be a species種類 very different不同 from you.
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將是一個翻天覆地的改變
16:34
Thank you very much.
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謝謝大家
16:36
(Applause掌聲)
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(掌聲)
Translated by Zheng Song
Reviewed by Ren Wan

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ABOUT THE SPEAKER
Juan Enriquez - Futurist
Juan Enriquez thinks and writes about the profound changes that genomics and other life sciences will bring in business, technology, politics and society.

Why you should listen

A broad thinker who studies the intersections of these fields, Enriquez has a talent for bridging disciplines to build a coherent look ahead. He is the managing director of Excel Venture Management, a life sciences VC firm. He recently published (with Steve Gullans) Evolving Ourselves: How Unnatural Selection and Nonrandom Mutation Are Shaping Life on Earth. The book describes a world where humans increasingly shape their environment, themselves and other species.

Enriquez is a member of the board of Synthetic Genomics, which recently introduced the smallest synthetic living cell. Called “JCVI-syn 3.0,” it has 473 genes (about half the previous smallest cell). The organism would die if one of the genes is removed. In other words, this is the minimum genetic instruction set for a living organism.

More profile about the speaker
Juan Enriquez | Speaker | TED.com

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