ABOUT THE SPEAKER
Russell Foster - Circadian neuroscientist
Russell Foster studies sleep and its role in our lives, examining how our perception of light influences our sleep-wake rhythms.

Why you should listen

Much as your ear does double duty (balance plus hearing), Russell Foster posits that the eye has two jobs: creating vision, but also -- as a completely separate function -- managing our perception of light and dark, providing the clues that our circadian rhythms need to regulate sleep-wake cycles. He and his team at the University of Oxford are exploring a third kind of photoreceptor in the eye: not a rod or a cone but a photosensitive retinal ganglion cell (pRGC) that detects light/dark and feeds that information to the circadian system. As Foster explains: "Embedded within our genes, and almost all life on Earth, are the instructions for a biological clock that marks the passage of approximately 24 hours." Light and dark help us synchronize this inner clock with the outside world.
 
The research on light perception hits home as we age -- faced with fading vision, we also risk disrupted sleep cycles, which have very serious consequences, including lack of concentration, depression and cognitive decline. The more we learn about how our eyes and bodies create our sleep cycles, the more seriously we can begin to take sleep as a therapy.

More profile about the speaker
Russell Foster | Speaker | TED.com
TEDGlobal 2013

Russell Foster: Why do we sleep?

Biz nega uxlaymiz?

Filmed:
8,011,042 views

Russel Foster miyadagi tun-kun almashinuviga bog'liq biologik soatni o'rganuvchi neyroshunos olimdir: U miyadagi uyqu jarayonini o'rganadi. Va shunday savol so'raydi: Biz uyqu haqida nima bilamiz? Ko'p emas, ayniqsa, bu umrimiznig uchdan bir qismi sarf bo'ladigan jarayon uchun. Bu ma'ruzada, Foster nima uchun uxlashimiz haqidagi eng keng tarqalgan uchta nazariyani, ba'zi yosh va uyquga bog'liq no'tog'ri tushunchalarni; hamda uyqu qanday qilib ruhiy sog'lomlikning ishorasi bo'lishi mumkinligi haqida gapiradi.
- Circadian neuroscientist
Russell Foster studies sleep and its role in our lives, examining how our perception of light influences our sleep-wake rhythms. Full bio

Double-click the English transcript below to play the video.

00:12
What I'd like to do today is talk about one
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Bugun men sizlarga mening eng
00:15
of my favorite subjects,
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sevimli mavzularimdan biri
00:16
and that is the neuroscience of sleep.
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uyqu nevrologiyasi haqida gapiraman.
00:20
Now, there is a sound --
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Shunday bir sado bor--
00:23
(Alarm clock) --
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( budilnik qo'ng'irog'i)
00:25
aah, it worked --
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aah, ana tas'ir qildi --
00:27
a sound that is desperately, desperately familiar to most of us,
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hammamizga juda yaxshi ma'lum bo'lgan shovqin bu,
00:30
and of course it's the sound of the alarm clock.
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bu albatta budilnik ovozi.
00:33
And what that truly ghastly, awful sound does
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Va bu eng yoqimsiz sado,
00:36
is stop the single most important behavioral experience
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biz uchun eng muhim bo'lgan
00:41
that we have, and that's sleep.
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uyquni to'xtatadi.
00:44
If you're an average sort of person,
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O'rta hisobda, odam umrining
00:48
36 percent of your life will be spent asleep,
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36 foizini uyquda kechiradi,
00:52
which means that if you live to 90,
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bu degani, agar 90 yil yashasangiz,
00:54
then 32 years will have been spent entirely asleep.
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32 yili tamoman uyquda kechadi.
01:01
Now what that 32 years is telling us
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Bu 32 yil bizga uyquning
01:03
is that sleep at some level is important.
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muhimligini anglatadi.
01:06
And yet, for most of us, we don't give sleep a second thought.
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Lekin, ko'pchiligimiz uyqu haqida uncha o'ylab ko'rmaymiz.
01:09
We throw it away.
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Biz uni chetda qoldiramiz.
01:11
We really just don't think about sleep.
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Biz rostdanam uyqu haqida o'ylamaymiz.
01:14
And so what I'd like to do today
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Shu sababli, bugun men
01:16
is change your views,
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sizlarning fikringizni o'zgartirmoqchiman,
01:18
change your ideas and your thoughts about sleep.
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ya'ni, sizning uyqu haqidagi fikrlaringizni.
01:21
And the journey that I want to take you on,
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Buning uchun men sizlarni
01:23
we need to start by going back in time.
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biroz ortga, tarixga nazar tashlashga undayman,
01:28
"Enjoy the honey-heavy dew of slumber."
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"Asal kabi chuqur uyqudan lazzat ol"
01:33
Any ideas who said that?
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Buni kim aytgan bilasizmi?
01:36
Shakespeare's Julius Caesar.
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Shekspirning Yuliy Tsezari.
01:39
Yes, let me give you a few more quotes.
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Men yana boshqa misollar keltiray.
01:42
"O sleep, O gentle sleep, nature's soft nurse,
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"Oh, uyqu, nozik uyqu, tabiatning yumshoq hamshirasi,
01:46
how have I frighted thee?"
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meni qanday qilib yengding?"
01:47
Shakespeare again, from -- I won't say it --
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Bu ham Shekspirdan, lekin qaysi asaridan
01:50
the Scottish play. [Correction: Henry IV, Part 2]
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aytmayman -- bu Shotlandiya pyessasi. [Genrix IV, 2 qism]
01:52
(Laughter)
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(Kulgi)
01:54
From the same time:
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Shu zamonlardan yana:
01:55
"Sleep is the golden chain
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Uyqu oltin zanjir kabi tanamiz
01:57
that ties health and our bodies together."
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va sog'lig'imizni birga tutar."
02:00
Extremely prophetic, by Thomas Dekker,
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Juda ham, uzoqni ko'ra bilgan Tomas Dekker,
02:02
another Elizabethan dramatist.
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yana bir Elizavetta zamonidagi dramatistlardan.
02:04
But if we jump forward 400 years,
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Eng 400 oldinga qaraylik,
02:07
the tone about sleep changes somewhat.
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uyqu haqidagi fikrlar biroz o'zgargan.
02:10
This is from Thomas Edison, from the beginning of the 20th century.
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Bu Tomas Edisondan, 20 asr boshlari.
02:14
"Sleep is a criminal waste of time
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" Uyqu bu jinoyat, vaqtni isrof etish
02:16
and a heritage from our cave days." Bang.
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va bu go'rda yashagan paytlarimizdan qolgan odat." Mana sizga!
02:18
(Laughter)
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(Kulgi)
02:21
And if we also jump into the 1980s, some of you
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1980 yilga o'tsak, ba'zilaringiz
02:25
may remember that Margaret Thatcher
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Margaret Tatcherni eslarsiz
02:27
was reported to have said, "Sleep is for wimps."
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uning "uyqu bo'shashgan odamlar uchun" degani haqida aytiladi.
02:31
And of course the infamous -- what was his name? --
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Va yaxshi tanilgan -- ha ismi nima edi?--
02:33
the infamous Gordon Gekko from "Wall Street" said,
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"Wall Street" kinosidagi Gordon Gekko,
02:36
"Money never sleeps."
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"Pul hech qachon uxlamaydi" degan.
02:38
What do we do in the 20th century about sleep?
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20 asrda biz uyqu uchun nima qilamiz?
02:41
Well, of course, we use Thomas Edison's light bulb
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albatta, Tomas Edisonning chirog'ini ishlatamiz
02:44
to invade the night, and we occupied the dark,
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kechalarimizga kirib, qorong'ilikni asir olish uchun,
02:47
and in the process of this occupation,
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va ishimizni davom ettira bilish uchun,
02:49
we've treated sleep as an illness, almost.
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biz uyquni huddi kassalikdek bilamiz.
02:52
We've treated it as an enemy.
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Biz uni dushmandek bilamiz.
02:55
At most now, I suppose, we tolerate the need for sleep,
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Ko'pincha uyqumiz kelgandan chidaymiz,
03:00
and at worst perhaps many of us think of sleep
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va balki ko'pchiligimiz uyquni bir kassalik deb tushunamiz,
03:03
as an illness that needs some sort of a cure.
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unga shifo topish kerak deb o'ylarmiz.
03:06
And our ignorance about sleep is really quite profound.
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Biz uyqu haqida bilmaganimiz juda ko'pdir.
03:10
Why is it? Why do we abandon sleep in our thoughts?
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Nega uyqu haqida o'ylab ko'rmaymiz?
03:13
Well, it's because you don't do anything much
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Chunki uxlaganda biz uncha ko'p narsa qilolmaymiz,
03:16
while you're asleep, it seems.
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shunday deb tushumaniz har holda.
03:17
You don't eat. You don't drink.
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Yemaymiz, ichmaymiz.
03:21
And you don't have sex.
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Jinsiy aloqaga kirmaymiz.
03:22
Well, most of us anyway.
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ko'pchiligimiz deymanda.
03:24
And so therefore it's --
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Va yana bir fikr --
03:26
Sorry. It's a complete waste of time, right? Wrong.
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Kechirasiz, vu vaqtni bekor ketkazish deb tushunamiz. Bu xato.
03:31
Actually, sleep is an incredibly important part of our biology,
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Aslida uyqu, bizning biologik faoliyatimiz uchun juda ham muhim.
03:35
and neuroscientists are beginning to explain why
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Va nevrologiya sohasida olimlar, uning muhimligini
03:38
it's so very important.
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tushununtirishni boshlashmoqda endi.
03:40
So let's move to the brain.
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Keling miyaga qaraylik.
03:43
Now, here we have a brain.
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Bu miya zhamiyat olimshunosi tomonidan
03:48
This is donated by a social scientist,
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bizga berilgan, ular buning
03:50
and they said they didn't know what it was,
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nima ekanligini bilmabdi
03:53
or indeed how to use it, so --
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har holda qanday ishlatishni
03:55
(Laughter)
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( kulgi)
03:58
Sorry.
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Uzr.
04:00
So I borrowed it. I don't think they noticed. Okay.
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Va men uni olib turdim. Ular payqamadi ham. mayli.
04:03
(Laughter)
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( kulgi)
04:06
The point I'm trying to make is that when you're asleep,
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Shunday demoqchimanki, uyqu paytida
04:09
this thing doesn't shut down.
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miya hech to'xtamaydi.
04:11
In fact, some areas of the brain are actually more active
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Aslida, miyaning ba'zi qismlari uyquda yanada ko'proq ishlaydi
04:13
during the sleep state than during the wake state.
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uyg'oq paytidagiga solishtirsak.
04:17
The other thing that's really important about sleep
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Uyquning yana bir muhim tomoni,
04:19
is that it doesn't arise from a single structure within the brain,
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u miyaning bir joyidan boshlanmaydi,
04:22
but is to some extent a network property,
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balki, o'zaro ta'sirdagi bogl'anishlardandir,
04:25
and if we flip the brain on its back --
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miyani orqa tomonini o'girsak --
04:27
I love this little bit of spinal cord here --
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men bu orqa miyani yaxshi ko'raman --
04:30
this bit here is the hypothalamus,
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a bu esa gipotalamusning bir qismi,
04:33
and right under there is a whole raft of interesting structures,
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uning ostida juda ajoyib qismlar bor
04:37
not least the biological clock.
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biologiya soati.
04:39
The biological clock tells us when it's good to be up,
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Bu biologik soat, miyamizga qachon tun va kun ekanligini
04:41
when it's good to be asleep,
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qachon uxlash, qachon uyg'onish kerakligini bildiirb turadi.
04:43
and what that structure does is interact
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Bu miyaning qismi boshqa qimslari bilan aloqadadir -
04:44
with a whole raft of other areas within the hypothalamus,
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gipotalamus hududigagi bir qancha miya qismlari bilan
04:48
the lateral hypothalamus, the ventrolateral preoptic nuclei.
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lateral gipotalmusi, venterolateral preoptic yadrosi bilan.
04:51
All of those combine, and they send projections
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Bularning hammasi bilan birlashib, miya ustunchasiga
04:53
down to the brain stem here.
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signal yuboradi.
04:55
The brain stem then projects forward
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Miya ustunchasi keyin, miyaning ustki qatlami korteksga
04:58
and bathes the cortex, this wonderfully wrinkly bit over here,
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mana bu ajoyib ajin tushgan o'xshash qatlamga,
05:02
with neurotransmitters that keep us awake
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bizni uyg'oq tutish uchun kerakli neyrotransmitterlar moddalarini yuboradi.
05:05
and essentially provide us with our consciousness.
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va bizni uyg'oq va sezgir holda tutadi.
05:07
So sleep arises from a whole raft
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Shunday qilib, uyqu miyaning
05:10
of different interactions within the brain,
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bir necha qismlari orasida o'zaro aloqadan kelib chiqadi,
05:12
and essentially, sleep is turned on and off
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va uyquning boshlanib to'xtashi bu yerdagi
05:15
as a result of a range of interactions in here.
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turli aloqalar natijasidir.
05:17
Okay. So where have we got to?
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Xullas, qayerga keldik?
05:19
We've said that sleep is complicated
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Uyqu bu murrakkab jarayon
05:23
and it takes 32 years of our life.
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va umrimizning 32 yili unga ketishi mumkin.
05:28
But what I haven't explained is what sleep is about.
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Lekin uyqu nega kerakligini hali aytmadim.
05:31
So why do we sleep?
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Nima uchun biz uxlaymiz?
05:33
And it won't surprise any of you that, of course,
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Hech kimni bu ajablantirmaydi -- biz olimlar
05:35
the scientists, we don't have a consensus.
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hali bir xulosaga kela olganimiz yo'q.
05:37
There are dozens of different ideas about why we sleep,
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Uxlash sabablari haqida ko'plab fikrlar mavjud,
05:40
and I'm going to outline three of those.
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men ularning uchtasini sizga havola etaman.
05:43
The first is sort of the restoration idea,
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Birinchi bu qayta tiklash sababi,
05:46
and it's somewhat intuitive.
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bu shundog'am tushunarli.
05:48
Essentially, all the stuff we've burned up during the day,
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Yani, kuni bilan sarf etgan kuch va kerakli narsalar
05:50
we restore, we replace, we rebuild during the night.
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tunda qayta tiklanadi demak.
05:54
And indeed, as an explanation,
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Bu fikr shuday qadimdan
05:55
it goes back to Aristotle,
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Aristotel zamonidan
05:57
so that's, what, 2,300 years ago.
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2,300 yil avval ham bor edi.
05:59
It's gone in and out of fashion.
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Bu modadan chiqib ketdi.
06:01
It's fashionable at the moment because what's been shown
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Hozir hammaning nazari
06:04
is that within the brain, a whole raft of genes
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miya ichidagi bir necha genlar
06:06
have been shown to be turned on only during sleep,
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faqat uydu paytida ishga tushishida
06:10
and those genes are associated with restoration
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va bu genlar qayta tiklash bilan bog'liq
06:12
and metabolic pathways.
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hamda metabolizm, modda almashinuvi bilan.
06:14
So there's good evidence for the whole restoration hypothesis.
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Shunday qilib, qayta tisklash gipotezasi uchun asos bor.
06:18
What about energy conservation?
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Energiyani saqlash gipotezasichi?
06:20
Again, perhaps intuitive.
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yana biz uchun ma'lum narsadek.
06:23
You essentially sleep to save calories.
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Siz kaloriya, energiya saqlash uchun uxlaysiz degan fikr.
06:26
Now, when you do the sums, though,
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lekin, hisoblab ko'rsangiz,
06:28
it doesn't really pan out.
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buning bir asosi yo'q.
06:30
If you compare an individual who has
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Agar siz tuni bilan uxlagan, va uyg'oq o'tirib
06:32
slept at night, or stayed awake and hasn't moved very much,
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uncha harakat qilmagan odamni taqqoslasangiz
06:37
the energy saving of sleeping is about 110 calories a night.
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uyquda faqatgina 110 kaloriya kam ishlatilgani topiladi.
06:42
Now, that's the equivalent of a hot dog bun.
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Bu hot dog bulochkasidagi energiya kabidir.
06:45
Now, I would say that a hot dog bun
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Va bu bir parcha nondagi energiya uchun
06:49
is kind of a meager return for such a complicated
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juda ham murakkab jaroyon
06:52
and demanding behavior as sleep.
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yani uyqu zarurligiga ishonmayman.
06:54
So I'm less convinced by the energy conservation idea.
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Men bu energiya saqlash gipotezasiga qo'shilmayman.
06:58
But the third idea I'm quite attracted to,
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Lekin uchinchi fikr meni o'ziga jalb etadi,
07:00
which is brain processing and memory consolidation.
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bu uyquda miyaning xotira ustida ishlashidir.
07:04
What we know is that, if after you've tried to learn a task,
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Biz shuni bilamsizki, agar uyqusiz odamlarga
07:07
and you sleep-deprive individuals,
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biror narsa o'rgatsangiz,
07:09
the ability to learn that task is smashed.
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ularning o'rganish qobiliyati juda ham pasayib ketadi.
07:12
It's really hugely attenuated.
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Bu qobiliyat juda ham kamayib ketadi.
07:15
So sleep and memory consolidation is also very important.
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Shu sababli, uyqu va xotirani mustahkamlash juda muhim.
07:18
However, it's not just the laying down of memory
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Lekin bu degani shunchaki yotib
07:21
and recalling it.
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xotiralarni eslash degani emas.
07:22
What's turned out to be really exciting
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Eng qizig'i shundaki, bizning murakkab muammolarga
07:24
is that our ability to come up with novel solutions
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yangi yechim topish qobiliyatimiz
07:28
to complex problems is hugely enhanced by a night of sleep.
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tungi uyqudan keyin ancha yaxshilanadi.
07:31
In fact, it's been estimated to give us a threefold advantage.
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Aslida, bu qobiliyat 3 marta oshadi, uyqudan so'ng.
07:35
Sleeping at night enhances our creativity.
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Tungi uyqu bizning ijodkorligimizni oshiradi.
07:38
And what seems to be going on is that, in the brain,
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Uyqu paytida miyada kerakli bo'lgan
07:40
those neural connections that are important,
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asab tarmoqlari kuchayib,
07:43
those synaptic connections that are important,
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muhim bo'lgan sinaptik bo'g'inlar kuchayib,
07:45
are linked and strengthened,
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bir biriga yanada mustahkam bog'lansa,
07:47
while those that are less important
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uncha muhim bo'lmaganlari
07:48
tend to fade away and be less important.
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susayib, ahamiyatini yoqota boradi.
07:52
Okay. So we've had three explanations for why we might sleep,
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Demak, biz uxlash sababi haqida uchta tushunchani ko'rib chiqdik.
07:56
and I think the important thing to realize is that
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Va eng muhumi, mening tushunishimcha, detallari turli bo'lsa ham
07:59
the details will vary, and it's probable we sleep for multiple different reasons.
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biz balki bir necha turli sabablar tufayli uxlaymiz.
08:03
But sleep is not an indulgence.
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Lekin uyqu bu hashamat emas.
08:06
It's not some sort of thing that we can take on board rather casually.
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Bu biz e'tiborsiz qoldiradigan narsa emas.
08:11
I think that sleep was once likened to an upgrade
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Kimdir uyquni samolyotdagi ekonom qismdan
08:14
from economy to business class, you know, the equiavlent of.
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biznez qisimga o'tishdek degandi.
08:17
It's not even an upgrade from economy to first class.
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Lekin menimcha, u ekonomdan birinchi qismga o'tishdek ham emas.
08:21
The critical thing to realize is that
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Muhimi, agar uxlamasangiz,
08:24
if you don't sleep, you don't fly.
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siz ucha ham olmaysiz.
08:28
Essentially, you never get there,
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Yani siz u kunlarni ko'rmaysiz agar uxlamasangiz.
08:30
and what's extraordinary about much of our society these days
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Bugungi kunda jamiyat ishonib bo'lmas darajada
08:33
is that we are desperately sleep-deprived.
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kam uxlaydi.
08:36
So let's now look at sleep deprivation.
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Keling, yetarlikcha uxlamaslik sababiga qaraylik,
08:38
Huge sectors of society are sleep-deprived,
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Jamiyatni katta qismi yetarlicha uxlamaydi.
08:41
and let's look at our sleep-o-meter.
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keling uyqu o'lchamiga qaraylik.
08:44
So in the 1950s, good data suggests that most of us
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1950 yillarda, raqamlar shuni ko'rsatadiki
08:48
were getting around about eight hours of sleep a night.
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ko'pchiligimiz tunda 8 soat uxlardik.
08:51
Nowadays, we sleep one and a half to two hours less every night,
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Bugungi kunda esa, biz har tunda bir yarim ikki soat kam uxlaymiz.
08:55
so we're in the six-and-a-half-hours-every-night league.
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yani tuniga olti, olti yarim soat uxlaymiz.
08:59
For teenagers, it's worse, much worse.
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O'spirin bundan ham kam uxlaydi.
09:02
They need nine hours for full brain performance,
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Ular miya faoliyati uchun 9 soat uxlashi kerak
09:05
and many of them, on a school night,
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lekin, ko'pchiligi maktab oldidan
09:07
are only getting five hours of sleep.
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kechasi faqat 5 soat uxlaydi.
09:09
It's simply not enough.
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Bu yetarli emas.
09:10
If we think about other sectors of society, the aged,
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Qariyalarga qarasak,
09:14
if you are aged, then your ability to sleep in a single block
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yosh oshgan sari tinimsiz uxlash kamayadi
09:18
is somewhat disrupted, and many sleep, again,
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uyqu bo'linib, ko'pchilik
09:21
less than five hours a night.
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kechasi faqat 5 soat uxlaydi.
09:22
Shift work. Shift work is extraordinary,
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Tunda ishlaydiganlar. Bu ajoyib hol.
09:25
perhaps 20 percent of the working population,
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ishchilarning 20 foizida
09:27
and the body clock does not shift to the demands
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tanadagi biologik soat ish vaqtiga mos kelmaydi.
09:31
of working at night.
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yani ular tunda ishlaydi.
09:32
It's locked onto the same light-dark cycle as the rest of us.
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Lekin ularning tanasi va miyasi ham biz kabi tun va kun aylanishiga qarab ishladyi.
09:34
So when the poor old shift worker is going home
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Bu bechora tuni bilan ishlaganlar, ertalab uyquga borib
09:37
to try and sleep during the day, desperately tired,
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uxlashga qattiq harakat qilsada, ularning miyasi
09:39
the body clock is saying, "Wake up. This is the time to be awake."
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tong otdi, kun chiqdi, hozir uyg'oq bo'lishing kerak deb qarshilik ko'rsatadi.
09:43
So the quality of sleep that you get as a night shift worker
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Shu sababli tuni bilan uxlagan tunda ishlaydigan odamning
09:46
is usually very poor, again in that sort of five-hour region.
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uyqu sifati pasayadi, huddi 5 soat uxlagan odamlar kabi.
09:49
And then, of course, tens of millions of people
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Va yana bizda, dunyoning har hil soat mintaqalaridan
09:51
suffer from jet lag.
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uchib kelib ketar odamlar bor.
09:53
So who here has jet lag?
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Kim hozir shunday vaqt farqidan toliqqan?
09:56
Well, my goodness gracious.
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1986
Buni qarangga,
09:58
Well, thank you very much indeed for not falling asleep,
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uxlab qolmaganingiz uchun rahmat.
10:01
because that's what your brain is craving.
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chunki hozir miyangiz uyquni xohlayapti.
10:03
One of the things that the brain does
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Miyada mikrojarayonlar bor
10:05
is indulge in micro-sleeps,
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ya'ni mikro uyqu, xohlamagan tarzda
10:09
this involuntary falling asleep,
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uxlab qolish,
10:11
and you have essentially no control over it.
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va siz buni boshqarolmaysiz.
10:13
Now, micro-sleeps can be sort of somewhat embarrassing,
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Mikro uyqu ba'zida bizni hijolatga qo'yadi,
10:15
but they can also be deadly.
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lekin ular o'limga ham olib kelishimi mumkin.
10:17
It's been estimated that 31 percent of drivers
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Ya'ni, 31 foiz haydovchilar mashina haydash paytida
10:21
will fall asleep at the wheel at least once in their life,
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uxlab qoladi. Kamida umrida bir marta,
10:25
and in the U.S., the statistics are pretty good:
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AQSHda statistika bo'yicha
10:28
100,000 accidents on the freeway
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katta yo'lda 100 ming avariya
10:31
have been associated with tiredness,
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charchoqlik, sergaklikning kamayishi,
10:33
loss of vigilance, and falling asleep.
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va uxlab qolish natijasida kelib chiqadi.
10:35
A hundred thousand a year. It's extraordinary.
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Yiliga 100 ming. Ishonib bo'lmas darajada.
10:37
At another level of terror,
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Yana boshqa qo'rqinchli tomoni,
10:39
we dip into the tragic accidents at Chernobyl
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Chernobil kabi favqulodda vaziyatlar,
10:43
and indeed the space shuttle Challenger,
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Challenger raketasi fojiasi
10:45
which was so tragically lost.
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tufayli yoq bo'lib ketish hollar bor.
10:47
And in the investigations that followed those disasters,
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Bu fojiali hollarni o'rganib chiqsak,
10:50
poor judgment as a result of extended shift work
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ish davomida odamlarni terang fikrlash,
10:54
and loss of vigilance and tiredness
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sergaklikning yoqolishi va charchash sabablari
10:56
was attributed to a big chunk of those disasters.
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ko'plab fojialarning orqasidan sabab ekanligi aniqlangan.
11:00
So when you're tired, and you lack sleep,
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Demak, charchab, uyqusirab turgan paydta
11:04
you have poor memory, you have poor creativity,
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xotirangiz susayadi, ijodkorlik kamayadii,
11:07
you have increased impulsiveness,
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o'ylamay tez ish qilish ortadi
11:10
and you have overall poor judgment.
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va umuman fahmlash jarayoni susayadi.
11:13
But my friends, it's so much worse than that.
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Lekin do'stlar, bundan ham yomon bo'lishi mumkin.
11:15
(Laughter)
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(kulgi)
11:18
If you are a tired brain,
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Agar miyangiz charchasa, uni
11:19
the brain is craving things to wake it up.
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sergak va uyg'oq tutadigan narsalarni xohlaydi.
11:22
So drugs, stimulants. Caffeine represents
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Har xil dorilar, sergaklantiruvchi narsalar. Kafein
11:26
the stimulant of choice across much of the Western world.
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shulardan biri, ayniqsa G'arbda keng istemol qilinadi.
11:30
Much of the day is fueled by caffeine,
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Kunimiz katta qismi kafein bilan bog'liq,
11:32
and if you're a really naughty tired brain, nicotine.
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agar juda ham tajang va charchoq miya bol'sa, nikotin dersiz.
11:35
And of course, you're fueling the waking state
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Miyani uyg'oq tutish uchun
11:37
with these stimulants,
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har hil moddalar iste'mol qilasiz
11:38
and then of course it gets to 11 o'clock at night,
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va tungi soat 11 da,
11:40
and the brain says to itself, "Ah, well actually,
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miyangiz albatta, "yaqin orada
11:42
I need to be asleep fairly shortly.
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uyquga ketishim kerak deydi.
11:44
What do we do about that when I'm feeling completely wired?"
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Lekin biz juda tetik va uxlagimiz kelmay tursa, ( kunduzgi kafein ta'sirida) biz nima qilamiz?"
11:47
Well, of course, you then resort to alcohol.
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Va albatta, siz alkogolga berilishingiz mumkin.
11:50
Now alcohol, short-term, you know, once or twice,
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Algokol, bir ikki marta sizni bo'shashtirishga
11:54
to use to mildly sedate you, can be very useful.
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yaxshi yordam berishi mimkin.
11:56
It can actually ease the sleep transition.
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U aslida uyquga elitishni osonlashtirish mumkin.
11:59
But what you must be so aware of
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Lekin shuni bilingki,
12:01
is that alcohol doesn't provide sleep,
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alkogol uyqu bermaydi,
12:05
a biological mimic for sleep. It sedates you.
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u biologik mimika qiladi, ya'ni sizni sekinlashtiradi
12:07
So it actually harms some of the neural proccessing
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yani, alkogol aslida ba'zi asab jarayonlariga ziyon yetkazadi
12:10
that's going on during memory consolidation
256
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1987
ya'ni, xotira mustahkamlash jarayonini
12:12
and memory recall.
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va esga olish jarayoniga salbiy ta'sir qiladi.
12:13
So it's a short-term acute measure,
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Bu boshqa chora qolmaganda qo'llanadigan hol,
12:16
but for goodness sake, don't become addicted
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lekin iltilmos tunda uxlay bilish uchun
12:18
to alcohol as a way of getting to sleep every night.
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alkogolga o'rganib qolmang.
12:21
Another connection between loss of sleep is weight gain.
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Uyqusizlikka bog'liq yana bir boshqa narsa bu ortiqcha semirishdir.
12:25
If you sleep around about five hours or less every night,
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Agar har tunda 5 soat va undan kam uxlasangiz
12:29
then you have a 50 percent likelihood of being obese.
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50 foiz hollarda ortiqcha semirishingiz mumkin.
12:32
What's the connection here?
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Bular qanday bog'langan?
12:34
Well, sleep loss seems to give rise to the release
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Uyqusizlik, Grelin gormonini oshiradi
12:37
of the hormone ghrelin, the hunger hormone.
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Grelin bu ochlik gormonidir.
12:40
Ghrelin is released. It gets to the brain.
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Grelin ishlab chiqarilib miyaga boradi.
12:43
The brain says, "I need carbohydrates,"
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Miya esa menga "menga (ovqatdagi) uglevodorodlar kerak" deydi
12:45
and what it does is seek out carbohydrates
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va kerakli uglevodorodlarni qo'msaydi
12:48
and particularly sugars.
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ayniqsa shakarni.
12:49
So there's a link between tiredness
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Charchash va modda almashinuvi
12:51
and the metabolic predisposition for weight gain.
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orasidagi bog'liqlik ortiqcha semirishga olib kelishi mumkin.
12:54
Stress. Tired people are massively stressed.
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Asabiylashish. Charchagan odamlar ko'p asabiylashadi.
12:59
And one of the things of stress, of course,
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Asabiylayshishning salbiy ta'sirlaridan biri
13:01
is loss of memory,
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xotiraning yo'qolishidir,
13:02
which is what I sort of just then had a little lapse of.
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huddi menda hozir biroz bolib o'tganday.
13:06
But stress is so much more.
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Lekin asabiylashish bundan ham ortiq ta'sir qiladi.
13:08
So if you're acutely stressed, not a great problem,
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Agar siz birdan asabiylashsangiz, bu katta muammo emas,
13:12
but it's sustained stress
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lekin davomiy asabiylashish,
13:13
associated with sleep loss that's the problem.
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uyqusizlik asabiylashishi, bu muammodir.
13:15
So sustained stress leads to suppressed immunity,
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Davomiy asabiylashish immunitenti susyatiradi,
13:20
and so tired people tend to have higher rates of overall infection,
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shuning uchun charchoq odamlar yuqumli kasalliklarga ko'p uchraydi,
13:23
and there's some very good studies showing
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va juda yaxshi o'rganilgan manbalar
13:25
that shift workers, for example, have higher rates of cancer.
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tunda ishlagan odamlar rak ( saraton) kasalligiga ko'proq uchrashini ko'rsatadi.
13:29
Increased levels of stress throw glucose into the circulation.
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Yuqori darajadagi asabiylashish qonga glyukozani ajratadi.
13:32
Glucose becomes a dominant part of the vasculature
286
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Glyukoza qon tomirlarda ko'payib ketib
13:36
and essentially you become glucose intolerant.
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organizmingiz glyukozani ko'tarolmay qoladi.
13:39
Therefore, diabetes 2.
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Shu sababli, 2 turdagi qand kassalligi kelib chiqadi.
13:41
Stress increases cardiovascular disease
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Asabiylashish yurak qon kasaliklaini ko'paytirib
13:45
as a result of raising blood pressure.
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qon bosimini oshiradi.
13:47
So there's a whole raft of things associated with sleep loss
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Shunday qilib uyqusizlik bilan bog'liq narsalar ko'p,
13:50
that are more than just a mildly impaired brain,
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bu miyaning salgina ishdan chiqqanidan emas
13:54
which is where I think most people think
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ko'pchilik o'ylagani kabi,
13:55
that sleep loss resides.
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bugina uyqusizlikni sababi emas.
13:57
So at this point in the talk, this is a nice time to think,
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Shu paytda, o'ylab ko'raylik
14:01
well, do you think on the whole I'm getting enough sleep?
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Kim o'zining yetarlicha uxlash haqida o'ylaydi?
14:04
So a quick show of hands.
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qo'llaringizni ko'tarsangiz.
14:05
Who feels that they're getting enough sleep here?
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Kim yetarlicha uxlayman deb o'ylaydi bu yerda?
14:08
Oh. Well, that's pretty impressive.
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Oh, bu juda yaxshi natija.
14:11
Good. We'll talk more about that later, about what are your tips.
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Yaxshi, birozdan so'ng qanday qilib yaxshi uxlash haqida gaplashamiz.
14:14
So most of us, of course, ask the question,
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Ko'pchiligimiz shuni so'raydi,
14:16
"Well, how do I know whether I'm getting enough sleep?"
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"men yetarlicha uxlaganimni qanday bilaman?'
14:18
Well, it's not rocket science.
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Bu hech qiyin masala emas.
14:20
If you need an alarm clock to get you out of bed in the morning,
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Agar ertalab turish uchun sizga budilnik kerak bo'lsa
14:23
if you are taking a long time to get up,
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uyg'onish uchun ko'p vaqt kerak bo'lsa
14:25
if you need lots of stimulants,
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1400
va sizni sergak tutuvchi moddalar kerak bo'lsa
14:27
if you're grumpy, if you're irritable,
307
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2028
o'zingizni kayfiyatsiz, injiq his qilsangiz
14:29
if you're told by your work colleagues
308
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2082
agar hamksablaringiz sizga
14:31
that you're looking tired and irritable,
309
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charchagan ko'rinasan, biroz asabiysan desa
14:33
chances are you are sleep-deprived.
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demak siz balki yetarlicha uxlamadingiz.
14:35
Listen to them. Listen to yourself.
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Siz ularga quloq soling. O'zingizni tinglang.
14:37
What do you do?
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Nima qilasiz?
14:39
Well -- and this is slightly offensive --
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1813
bu biroz sizga tegib ketishi mumkin
14:41
sleep for dummies:
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bilmagan soddalar uchun yaxshi uxlash sirlari:
14:44
Make your bedroom a haven for sleep.
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Yotoqxonangizni uyqu uchun jannatdek qiling.
14:47
The first critical thing is make it as dark as you possibly can,
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3626
Eng muhumi uni qorong'i qilishdir,
14:51
and also make it slightly cool. Very important.
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va biroz salqin bo'lsin. bu juda muhim.
14:53
Actually, reduce your amount of light exposure
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Aslida, uxlashdan yarim bir soat oldin
14:56
at least half an hour before you go to bed.
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yo'rug'lik ta'sirini kamaytiring.
14:59
Light increases levels of alertness and will delay sleep.
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Yorug'lik, odamni sergaklantirib uyqunu kechiktiradi.
15:01
What's the last thing that most of us do before we go to bed?
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2557
Uyqudan oldin ko'pchiligimiz nima qilamiz?
15:04
We stand in a massively lit bathroom
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2469
Juda ham yorug' hojatxonada
15:06
looking into the mirror cleaning our teeth.
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oynaga qarab tish yuvamiz.
15:09
It's the worst thing we can possibly do
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Bu uyqudan oldin bundan
15:11
before we went to sleep.
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yomon narsa qilmasang kerak.
15:12
Turn off those mobile phones. Turn off those computers.
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Uyali telefonlarni o'chiring. Komyuterlarni o'chiring.
15:15
Turn off all of those things that are also going to excite the brain.
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Miyangizni faollashtiradigan hamma narsalarni o'chiring.
15:19
Try not to drink caffeine too late in the day,
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Kun kech bo'lganda kafein ichmaslikka harakat qiling,
15:22
ideally not after lunch.
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eng yaxshisi tushlik paytidan boshlab ichmang.
15:25
Now, we've set about reducing light exposure before you go to bed,
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3457
Uyqudan oldin yorug'likni kamaytiring dedik,
15:29
but light exposure in the morning
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1721
lekin ertalab yorug'lik badandagi
15:30
is very good at setting the biological clock to the light-dark cycle.
332
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kun va tunni aniqlaydigan soatimiz uchun juda zarur.
15:34
So seek out morning light.
333
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Shuning uchun ertalabku kunni ko'ring.
15:35
Basically, listen to yourself.
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2570
Xullas, o'zingizga ishoning, tinglang.
15:38
Wind down. Do those sorts of things that you know
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Sekin asta, o'zingiz bilasiz, sizni
15:41
are going to ease you off
336
929439
1392
osoyishta qiladigan narsalar qilingki
15:42
into the honey-heavy dew of slumber.
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uyquning shirin oromiga elitsin.
15:46
Okay. That's some facts. What about some myths?
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Bular faktlar edi. Endi ba'zi afsonalar bor.
15:49
Teenagers are lazy. No. Poor things.
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O'spirinlar yolqov deysiz. Yo'q. O, bechoralar
15:52
They have a biological predisposition
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ularning biologiyasi shunga moslashgan
15:54
to go to bed late and get up late, so give them a break.
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kech yotib, kech turishadi, shuning uchun ularni o'z holiga qo'ying.
15:57
We need eight hours of sleep a night.
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Tunda bizga 8 soat uyqu kerak degan gap bor.
16:01
That's an average. Some people need more. Some people need less.
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Bu o'rta hisobda. Ba'zilarga ko'proq uyqu kerak. Ba'zilarga kamroq.
16:05
And what you need to do is listen to your body.
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Buning uchun tanangizga quloq soling.
16:07
Do you need that much or do you need more?
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Sizga shuncha uyqu kerakmi? balki ko'proq yoki ozroq kerak?
16:09
Simple as that.
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Buni bilish ana shunday oson.
16:10
Old people need less sleep. Not true.
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Qariyalarga kam uyqu kerak degan gap bor. Bu noto'g'ri.
16:14
The sleep demands of the aged do not go down.
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Yosh oshgan sari uyquga hojat kamaymaydi.
16:17
Essentially, sleep fragments and becomes less robust,
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Balki uyqu tez-tez buzilib, bo'lib bo'lib uxlaydigan bo'lib qoladi.
16:20
but sleep requirements do not go down.
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lekin qancha uyqu kerakligi kamaymaydi.
16:23
And the fourth myth is,
351
971247
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4- noto'g'ri tushuncha esa
16:25
early to bed, early to rise
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973475
1913
erta yotib erta turish
16:27
makes a man healthy, wealthy and wise.
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kishini sog', boy va aqlli qiladi deyishdir.
16:30
Well that's wrong at so many different levels.
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Bu har tomonlama noto'g'ri gap.
16:32
(Laughter)
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(kulgi)
16:35
There is no, no evidence that getting up early
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Erta turishning va erta yotishning sizga
16:38
and going to bed early gives you more wealth at all.
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boylik olib kelishi haqida hech qanday asos yo'q.
16:41
There's no difference in socioeconomic status.
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Jamiyatdagi iqtisodiy sinf va tabaqalar orasida farq yo'q.
16:44
In my experience, the only difference between
359
992167
1790
Menimcha, erta turadigan yoki kech faol odamlar
16:45
morning people and evening people
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orasidagi yagona farq shuki
16:47
is that those people that get up in the morning early
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erat turadigan odamlar
16:50
are just horribly smug.
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haddan tashqari o'zicha maqtanchoqlar.
16:52
(Laughter) (Applause)
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( kulgi, qarsak)
16:56
Okay. So for the last part, the last few minutes,
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Mayli, qolgan bir ikki daqiqa ichidan
16:59
what I want to do is change gears
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1007408
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boshqa bir yangilik haqida gapiraylik
17:01
and talk about some really new, breaking areas of neuroscience,
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bu neyrologiya sohasida yangilik
17:04
which is the association between mental health,
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1012824
3016
yani ruhiy hastaliklar
17:07
mental illness and sleep disruption.
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2277
va uyqusizlik orasidagi bog'liq.
17:10
We've known for 130 years that in severe mental illness,
369
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130 yildan beri biz ruhiy hastalarda doimo,
17:13
there is always, always sleep disruption,
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har doimo, uyqusizlik bo'lganini bilamiz.
17:17
but it's been largely ignored.
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lekin bu e'tirbordan chetda qolgandi.
17:19
In the 1970s, when people started to think about this again,
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1970 yillarda, odamlar buni ustida qayta o'ylash boshlagan,
17:21
they said, "Yes, well, of course you have sleep disruption
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va " albatta ular yaxshi uxlay olmaydi,
17:24
in schizophrenia because they're on anti-psychotics.
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3653
chunki shizofreniya hastalari miyaga ta'sir qiluvchi dorilar ichadi
17:27
It's the anti-psychotics causing the sleep problems,"
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va bu dorilar uyqusizlik muammosini keltirib chiqaradi" deyishgan
17:30
ignoring the fact that for a hundred years previously,
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Lekin,ular shuni unutishadiki, ruhiy hastalikka qarshi
17:33
sleep disruption had been reported before anti-psychotics.
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dorilar paydo bo'lmasdan yuz yillar oldin ham uyqu buzilish bor edi.
17:37
So what's going on?
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Unda nima bo'layapti?
17:39
Lots of groups, several groups are studying
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Ko'p olimlar, tushkunlik ( depressiya), shizofreniya
17:42
conditions like depression, schizophrenia and bipolar,
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ya bipolyar hastaliklarini o'rganishmoqda
17:46
and what's going on in terms of sleep disruption.
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va ularning uyquga ta'sirini.
17:48
We have a big study which we published last year on schizophrenia,
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O'tgan yili ilmiy maqola shizofreniya haqida
17:52
and the data were quite extraordinary.
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bir ajoyib ma'lumot berdi.
17:55
In those individuals with schizophrenia,
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Shizofreniya hastalari,
17:58
much of the time, they were awake during the night phase
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tunning ko'p qismini uyqusiz o'tkasib,
18:02
and then they were asleep during the day.
386
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kunduzning ko'p qismini uyquda o'tkazadi
18:04
Other groups showed no 24-hour patterns whatsoever.
387
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Lekin boshqa guruhdagilarda bundan 24 soatli tartib bo'lmagan.
18:07
Their sleep was absolutely smashed.
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2256
Boshqa guruhlar uyqusi umuman buzilgan edi.
18:09
And some had no ability to regulate their sleep by the light-dark cycle.
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3891
Ba'zilari uyquni yorug'lik va qorong'ulikka qarab boshqarolmagan.
18:13
They were getting up later and later and later
390
1081618
1762
Ular har safar kechroq va yana kechroq
18:15
and later each night. It was smashed.
391
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2782
tunlarda uyg'ongan. Ularda bu tartib umuman yo'q bo'lgan.
18:18
So what's going on?
392
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Unda nima bo'layapti?
18:20
And the really exciting news is that
393
1088327
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Eng qiziq yangilik shuki,
18:23
mental illness and sleep are not simply associated
394
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ruhiy kasallik va uyqusizlik shunchaki o'zaro bog'liq emas
18:27
but they are physically linked within the brain.
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3028
balki ular miyada o'zaro fizik bo'gliqlikka ega.
18:30
The neural networks that predispose you to normal sleep,
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Sizga odatdagi uyqu beruvchi asab to'rlari
18:33
give you normal sleep, and those that give you
397
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2178
va sizga sog'lom ruhiy va psihologik jarayonlarni ta'minlovchi
18:35
normal mental health are overlapping.
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2714
asab to'rlarnni o'zaro bog'langan.
18:38
And what's the evidence for that?
399
1106234
1763
Buning asosi qani?
18:39
Well, genes that have been shown to be very important
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1107997
3708
Asosi, biz juda muhim genlarning
18:43
in the generation of normal sleep,
401
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2265
sog'lom uyqu jarayoni ustida ishlashini
18:45
when mutated, when changed,
402
1113970
1381
va agar ular, mutatsiya ta'sirida o'zgarsa
18:47
also predispose individuals to mental health problems.
403
1115351
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odamlar, ruhiy hastaliklarga chalinishi mumkinligini bilamsiz.
18:50
And last year, we published a study
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1118716
2001
O'tgan yili, ilmiy maqola chop etilgandi,
18:52
which showed that a gene that's been linked to schizophrenia,
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1120717
3529
unda shizofreniya hastaligiga bog'liq gen
18:56
which, when mutated, also smashes the sleep.
406
1124246
3633
mutatsiya bo'lib o'zgargandi, uyqu jarayonini buzgani aniqlangan.
18:59
So we have evidence of a genuine mechanistic overlap
407
1127879
3153
Shunday qilib bizda, rostdan ham bu ikki juda muhim
19:03
between these two important systems.
408
1131032
2764
sistema orasida mehanik bog'liklik borligiga asos dalil bor.
19:05
Other work flowed from these studies.
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Bu ilmiy topilma asosisda yana boshqa ilmiy ishlar qilindi.
19:07
The first was that sleep disruption actually precedes
410
1135969
4916
Birinchidan, uyqusizlik aslida ba'zi ruhiy hastaliklar
19:12
certain types of mental illness,
411
1140885
2038
paydo bo'lishidan oldin sodir bo'lishi aniqlandi.
19:14
and we've shown that in those young individuals
412
1142923
2677
Va biz shuni ko'rsatib bera oldikki, yoshlarda
19:17
who are at high risk of developing bipolar disorder,
413
1145600
2919
bipolyar hastalik xavfi katta bo'lgan odamlarda
19:20
they already have a sleep abnormality
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2629
oldindan uyqu buzilishi borligini aniqladik.
19:23
prior to any clinical diagnosis of bipolar.
415
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4036
Ya'ni bu, bipolyar (tashxisi) diagnozi qo'yilishidan oldin.
19:27
The other bit of data was that sleep disruption
416
1155184
5779
Yana boshqa manba'larga ko'ra
19:32
may actually exacerbate,
417
1160963
1818
uyqusizlik ruhiy hastalikni
19:34
make worse the mental illness state.
418
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2625
yana og'irlashitrishi topilgan.
19:37
My colleague Dan Freeman has used a range of agents
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2499
Hamkasbim Dan Freeman, har xil usullar bilan
19:39
which have stabilized sleep and reduced levels of paranoia
420
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3797
uyquni yaxshilab, paranoya darajalarini kamaytira bildi,
19:43
in those individuals by 50 percent.
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yani 50 foizga kamaytira oldi.
19:46
So what have we got?
422
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Bu nima degani?
19:47
We've got, in these connections, some really exciting things.
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Bu o'zaro bog'liqlikda biz juda qiziq narsalar topdik.
19:53
In terms of the neuroscience, by understanding
424
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1910
Neyrologiya faniga ko'ra,
19:55
the neuroscience of these two systems,
425
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1268
bu ikki tarmoqning ishlash jarayonini
19:56
we're really beginning to understand how both sleep
426
1184668
2411
uyqu va ruhiy hastalik kelib chiqishining
19:59
and mental illness are generated and regulated within the brain.
427
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4078
miyada qanday boshqarilishini endi tushuna boshladik.
20:03
The second area is that if we can use sleep
428
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3727
Ikkinchi tomoni esa, biz uyqu jarayoni
20:06
and sleep disruption as an early warning signal,
429
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uning buzilishini oldindan signal, ishora
20:09
then we have the chance of going in.
430
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2337
sifatida e'tiborga olsak bo'ladi.
20:11
If we know that these individuals are vulnerable,
431
1199467
2589
Agar biz bu shaxslar bu uyqu sohasida ojiz va ta'sirchan bo'lsa
20:14
early intervention then becomes possible.
432
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2493
balki oldindan ruhiy hastalik oldini olish mumkin bo'lar.
20:16
And the third, which I think is the most exciting,
433
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Uchinchidan, menimcha eng ajoyibi shundaki
20:19
is that we can think of the sleep centers within the brain
434
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miya ichidagi uyqu markazlarini
20:21
as a new therapeutic target.
435
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1590
davolash nuqtalari deb bilsak bo'ladi.
20:23
Stabilize sleep in those individuals who are vulnerable,
436
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Ojiz va kasallika himoyasiz odamlar uyqusini yaxshilang
20:25
we can certainly make them healthier,
437
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2366
va ularning sog'ligini mustahkamlanadi
20:28
but also alleviate some of the appalling symptoms of mental illness.
438
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hamda, ba'zi ruhiy hastaliklarning ahvolini yengillashtiradi.
20:33
So let me just finish.
439
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Xullas, yakun yasay.
20:34
What I started by saying is take sleep seriously.
440
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Men uyquga jiddiy qarash kerak deb boshladim.
20:37
Our attitudes toward sleep are so very different
441
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Bizning uyquga bo'lgan aloqamiz
20:40
from a pre-industrial age,
442
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1205
industriya erasidan oldingiga nisbatan boshqacha
20:41
when we were almost wrapped in a duvet.
443
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U paytda biz ko'rpalarga o'ralib yotardik
20:43
We used to understand intuitively the importance of sleep.
444
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Uyquning ahamiyatini tabiatan bilardik
20:47
And this isn't some sort of crystal-waving nonsense.
445
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Va bu bekor gap emas,
20:50
This is a pragmatic response to good health.
446
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2832
balki sog'liq uchun juda o'rinli javob.
20:53
If you have good sleep, it increases your concentration,
447
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2925
Yaxshi uxlasangiz, fikrni jamlash qobiliyati oshadi
20:56
attention, decision-making, creativity, social skills, health.
448
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3833
diqqat, qaror qabul qilish, ijodkorlik, odamlar aro munosabat, sog'liq kuchayadi.
21:00
If you get sleep, it reduces your mood changes, your stress,
449
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4282
Yetarlicha uxlash kayfiyat tushib chiqishini, asabiylashishni kamaytiradi
21:04
your levels of anger, your impulsivity,
450
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2196
jahl, va tezqonlikni susaytiradi,
21:06
and your tendency to drink and take drugs.
451
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hamda ichkilikka berilish turli dorilar qabul qilishni.
21:09
And we finished by saying
452
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Va shunday xulosaga keldikki
21:12
that an understanding of the neuroscience of sleep
453
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uyqu neyrologiya fanini tushunish
21:15
is really informing the way we think about
454
1263267
3372
biz chindan ham
21:18
some of the causes of mental illness,
455
1266639
2115
ruhiy kasalliklar haqida
21:20
and indeed is providing us new ways
456
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yangi fikrlashga
21:22
to treat these incredibly debilitating conditions.
457
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va bu bizni kuchsizlantiradigan avhollarni davolashga yo'l ochadi.
21:27
Jim Butcher, the fantasy writer, said,
458
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Fantastik yozuvchi, Jim Butcher shunday degan:
21:31
"Sleep is God. Go worship."
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"Uyqu xudodir. Boring unga ibodat qiling"
21:33
And I can only recommend that you do the same.
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Va men ham sizga buni taklif qilaman.
21:35
Thank you for your attention.
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E'tiboringiz uchun rahmat.
21:36
(Applause)
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( qarsaklar)
Translated by Nafissa Yakubova
Reviewed by Gulnoza Yakubova

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ABOUT THE SPEAKER
Russell Foster - Circadian neuroscientist
Russell Foster studies sleep and its role in our lives, examining how our perception of light influences our sleep-wake rhythms.

Why you should listen

Much as your ear does double duty (balance plus hearing), Russell Foster posits that the eye has two jobs: creating vision, but also -- as a completely separate function -- managing our perception of light and dark, providing the clues that our circadian rhythms need to regulate sleep-wake cycles. He and his team at the University of Oxford are exploring a third kind of photoreceptor in the eye: not a rod or a cone but a photosensitive retinal ganglion cell (pRGC) that detects light/dark and feeds that information to the circadian system. As Foster explains: "Embedded within our genes, and almost all life on Earth, are the instructions for a biological clock that marks the passage of approximately 24 hours." Light and dark help us synchronize this inner clock with the outside world.
 
The research on light perception hits home as we age -- faced with fading vision, we also risk disrupted sleep cycles, which have very serious consequences, including lack of concentration, depression and cognitive decline. The more we learn about how our eyes and bodies create our sleep cycles, the more seriously we can begin to take sleep as a therapy.

More profile about the speaker
Russell Foster | Speaker | TED.com

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