ABOUT THE SPEAKER
Jim Fallon - Neurobiologist
Sloan Scholar, Fulbright Fellow, Professor Emeritus of Neuroscience, Jim Fallon looks at the way nature and nurture intermingle to wire up the human brain.

Why you should listen

Jim Fallon has taught neuroscience and psychiatry grand rounds at the University of California Irvine for thirty-five years. Through research he explores the way genetic and perinatal environmental factors affect the way the brain gets built -- and then how an individual's experience further shapes his or her development. He lectures and writes on creativity, consciousness and culture, and has made key contributions to our understanding of adult stems and stroke, schizophrenia, Parkinson's disease and Alzheimer's disease.

Only lately has Fallon turned his research toward the subject of psychopaths -- particularly those who kill. With PET scans and EEGs, he's beginning to uncover the deep, underlying traits that make people violent and murderous. In his talk at TEDDIY at TED@PalmSprings, he shared a surprise discovery about his own family that prompted him to bring his work home.

Watch his followup talk from The Moth at the 2011 World Science Festival >>

More profile about the speaker
Jim Fallon | Speaker | TED.com
TED2009

Jim Fallon: Exploring the mind of a killer

Jim Fallon: Istraživanje mozga ubojice

Filmed:
2,772,955 views

Ubojice psihopati glavna su tema nekih „obavezno-pogledajte“ filmova, ali postavlja se pitanje, što je ono što „okida“ takve osobe. Neuroznanstvenik Jim Fallon govori o skenovima mozga i genetičkim analizama koji bi mogli otkriti uzrok podle prirode (i odgoja) tih ubojica. U svom govoru dijeli fascinantnu obiteljsku povijest koja njegov rad čini osobnim.
- Neurobiologist
Sloan Scholar, Fulbright Fellow, Professor Emeritus of Neuroscience, Jim Fallon looks at the way nature and nurture intermingle to wire up the human brain. Full bio

Double-click the English transcript below to play the video.

00:18
I'm a neuroscientistneuroznanstvenik, a professorprofesor at the UniversitySveučilište of CaliforniaCalifornia.
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Neuroznanstvenik sam i profesor na Sveučilištu u Kaliforniji.
00:21
And over the pastprošlost 35 yearsgodina,
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Posljednjih 35 godina,
00:24
I've studiedstudirao behaviorponašanje
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proučavao sam ponašanje
00:26
on the basisosnova of everything from genesgeni
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od gena
00:29
throughkroz neurotransmittersneurotransmitori, dopaminedopamin, things like that,
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do neurotransmitera, dopamina, i sličnih stvari,
00:31
all the way throughkroz circuitstrujni krug analysisanaliza.
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i sve putem kružnih analiza.
00:33
So that's what I normallynormalno do.
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Dakle, to je uglavnom ono čime se inače bavim.
00:35
But then, for some reasonrazlog,
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Ali onda, iz nekog razloga,
00:37
I got into something elsedrugo, just recentlynedavno.
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baš nedavno uvukao sam se u nešto drugačije.
00:39
And it all grewrastao out of one of my colleagueskolege askingtraži me
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Sve je to bilo potaknuto molbom jednoga kolege
00:42
to analyzeanalizirati a bunchmnogo of brainsmozak
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da analiziram hrpu mozgova
00:44
of psychopathicpsihijatrijski killersubojice.
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ubojica psihopata.
00:46
And so this would be the typicaltipičan talk I would give.
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Dakle, ovo bi bio moj tipičan govor.
00:49
And the questionpitanje is, "How do you endkraj up with a psychopathicpsihijatrijski killerubica?"
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A pitanje je, „Kako postanete psihopatski ubojica?“
00:52
What I mean by psychopathicpsihijatrijski killerubica
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Kada govorim o ubojicama psihopatima,
00:54
are these people, these typesvrste of people.
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mislim zapravo na određene tipove ljudi.
00:56
And so some of the brainsmozak that I've studiedstudirao
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Neki od mozgova koje sam proučavao,
00:58
are people you know about.
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pripadaju ljudima o kojima nešto i znate.
01:00
When I get the brainsmozak I don't know what I'm looking at.
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Kada dođem u doticaj s mozgom, ne znam u što gledam.
01:02
It's blindslijep experimentspokusi. They alsotakođer gavedali me normalnormalan people and everything.
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To su bili slijepi eksperimenti. Također sam dobivao i mozgove normalnih ljudi.
01:04
So I've lookedgledao at about 70 of these.
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Pogledao sam ih otprilike 70.
01:06
And what camedošao up was a numberbroj of pieceskomada of datapodaci.
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I ono što je proizašlo bilo je mnoštvo podataka.
01:09
So we look at these sortsvrste of things theoreticallyteoretski,
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Proučavamo ovakve stvari teoretski,
01:12
on the basisosnova of geneticsgenetika,
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na temelju genetičkih čimbenika,
01:14
and brainmozak damagešteta, and interactioninterakcija with environmentokolina,
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oštećenja mozga i interakcije s okolinom,
01:17
and exactlytočno how that machinemašina worksdjela.
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te točnog načina na koji taj „stroj“ radi.
01:19
So we're interestedzainteresiran in exactlytočno where in the brainmozak,
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Nas stoga zanima gdje točno u mozgu
01:21
and what's the mostnajviše importantvažno partdio of the brainmozak.
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i koji je najvažniji dio mozga.
01:23
So we'veimamo been looking at this:
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Stoga smo proučavali slijedeće:
01:26
the interactioninterakcija of genesgeni,
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interakciju gena,
01:28
what's calledzvao epigeneticEpigenetske effectsefekti,
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tj. epigenetske utjecaje,
01:30
brainmozak damagešteta, and environmentokolina,
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moždana oštećenja i okolinu,
01:32
and how these are tiedvezan togetherzajedno.
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i kako su navedene stvari međusobno povezane.
01:34
And how you endkraj up with a psychopathpsihopat, and a killerubica,
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Kako postanete psihopat i ubojica
01:36
dependsovisi on exactlytočno when the damagešteta occursjavlja.
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ovisi točno o vremenu nastanka oštećenja.
01:39
It's really a very preciselyprecizno timedvremenski thing.
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To je vremenski vrlo precizna stvar.
01:42
You get differentdrugačiji kindsvrste of psychopathspsihopati.
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Dobijete različite vrste psihopata.
01:44
So we're going alonguz with this. And here'sevo, just to give you the patternuzorak.
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I dok pričamo o ovome, ukazat ću vam na uzorak
01:47
The patternuzorak is that those people, everysvaki one of them I lookedgledao at,
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koji se ponavljao kod ispitanika - svi ti ljudi, koje sam pojedinačno proučavao,
01:50
who was a murdererubica, and was a serialserijski killerubica,
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i koji su bili ubojice i serijski ubojice,
01:53
had damagešteta to theirnjihov orbitalorbitalna cortexkorteks,
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imali su oštećenje orbitalnog korteksa.
01:55
whichkoji is right aboveiznad the eyesoči, the orbitsorbite,
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To područje smješteno je odmah iznad očiju, orbita,
01:57
and alsotakođer the interiorunutrašnjost partdio of the temporalvremenski loberežanj.
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također i unutrašnjeg dijela sljepoočnog režnja.
01:59
So there is the patternuzorak that everysvaki one of them had,
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To je dakle uzorak koji se kod svih njih ponavljao,
02:01
but they all were a little differentdrugačiji too.
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ali ipak se oni malo i razlikuju.
02:03
They had other sortsvrste of brainmozak damagešteta.
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Imali su različite vrste moždanih oštećenja.
02:05
A keyključ thing is that
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Ključna stvar je utjecaj
02:07
the majorglavni violencenasilje genesgeni,
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glavnih gena, posrednika nasilnog ponašanja,
02:10
it's calledzvao the MAO-AMAO-A genegen.
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poput MAO-A gena.
02:13
And there is a variantvarijanta of this genegen that is in the normalnormalan populationpopulacija.
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Varijanta ovoga gena postoji u normalnoj populaciji.
02:17
Some of you have this. And it's sex-linkedvelikog.
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Neki od vas je imaju. On je spolno vezan.
02:20
It's on the X chromosomekromosom. And so in this way
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Nalazi se na X kromosomu. Stoga, možete ju
02:22
you can only get it from your mothermajka.
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naslijediti samo od svoje majke.
02:25
And in factčinjenica this is probablyvjerojatno why mostlyuglavnom menmuškarci, boysdječaci,
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To je vjerojatno i uzrok pojave da su
02:29
are psychopathicpsihijatrijski killersubojice,
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psihopatski ubojice većinom muškarci
02:31
or are very aggressiveagresivan.
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ili su vrlo agresivni.
02:33
Because a daughterkći can get one X from the fatherotac,
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Budući da kćeri nasljeđuju jedan X kromosom od oca
02:36
one X from the mothermajka, it's kindljubazan of dilutedrazrijeđen out.
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a jedan X kromosom od majke, nije toliko česta pojava u ženskog spola. .
02:38
But for a sonsin, he can only get
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A što se tiče sina,
02:40
the X chromosomekromosom from his mothermajka.
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on X kromosom nasljeđuje samo od majke
02:42
So this is how it's passedprošao from mothermajka to sonsin.
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I tako se prenosi sa majke na sina.
02:45
And it has to do with too much brainmozak serotoninserotonin duringza vrijeme developmentrazvoj,
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Ova pojava ima veze sa previše moždanog serotonina tijekom razvoja.
02:49
whichkoji is kindljubazan of interestingzanimljiv because serotoninserotonin
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Što je zapravo zanimljivo, budući da bi vas serotonin
02:51
is supposedtrebala to make you calmsmiriti and relaxedopušteno.
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trebao umirivati i opuštati.
02:54
But if you have this genegen, in uteromaternicom
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Ali ako nosite ovaj gen, vaš se mozak u intrauterinom
02:57
your brainmozak is bathedokupan in this,
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razvoju „kupa“ u serotoninu.
02:59
so your wholečitav brainmozak becomespostaje insensitiveneosjetljiv to serotoninserotonin,
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Stoga vaš cijeli mozak postaje neosjetljiv na serotonin.
03:01
so it doesn't work laterkasnije on in life.
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Zbog toga, on nema utjecaj na vas kasnije u životu.
03:04
And I'd givendan this one talk in IsraelIzrael,
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Držao sam jedan govor u Izraelu
03:07
just this pastprošlost yeargodina.
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prošle godine.
03:09
And it does have some consequencesposljedice.
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I imao je iste posljedice.
03:11
TheoreticallyTeoretski what this meanssredstva
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U teoretskom smislu,
03:13
is that in ordernarudžba to expressizraziti this genegen,
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da bi došlo do ekspresije ovoga gena,
03:16
in a violentnasilan way,
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na nasilan način,
03:18
very earlyrano on, before pubertypubertet,
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morali biste vrlo rano, prije puberteta,
03:20
you have to be involvedumiješan in something that is really traumatictraumatičan --
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biti uključeni u nešto izrazito traumatično,
03:23
not a little stressstres, not beingbiće spankedčiniti or something,
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ne lagano pod stresom, ne biti išamaran ili nešto slično.
03:25
but really seeingvidim violencenasilje,
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Nego zaista prisustvovati nasilju
03:27
or beingbiće involvedumiješan in it, in 3D.
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ili biti upleten u njega, kao 3D.
03:29
Right? That's how the mirrorogledalo neuronneuron systemsistem worksdjela.
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Točno? Na takav način funkcionira živčani sustav.
03:31
And so, if you have that genegen,
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I ukoliko posjedujete taj gen,
03:34
and you see a lot of violencenasilje
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i svjedokom ste učestalih nasilnih
03:37
in a certainsiguran situationsituacija,
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situacija,
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this is the reciperecept for disasterkatastrofa, absoluteapsolutan disasterkatastrofa.
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to vam je recept za katastrofu, apsolutnu katastrofu.
03:42
And what I think mightmoć happendogoditi se in these areaspodručja of the worldsvijet,
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I ono što mislim da bi se moglo dogoditi u dijelovima svijeta
03:45
where we have constantkonstantno violencenasilje,
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u kojima je prisutno konstantno nasilje,
03:48
you endkraj up havingima generationsgeneracije of kidsdjeca
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jest da završite sa generacijama djece
03:51
that are seeingvidim all this violencenasilje.
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koja prisustvuju tom nasilju.
03:53
And if I was a youngmladi girldjevojka, somewherenegdje in a violentnasilan areapodručje,
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Da sam ja djevojka, okružena nasiljem,
03:56
you know, a 14 yeargodina oldstar, and I want to find a matemat u šahu,
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znate, 14-godišnjakinja, i poželim si naći dečka,
03:58
I'd find some toughtvrd guy, right, to protectzaštititi me.
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tražila bi nekog opasnog tipa, da me zaštiti.
04:01
Well what the problemproblem is this tendsteži to concentratekoncentrat these genesgeni.
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I ono što predstavlja problem je što takvi postupci teže koncentriranju takvih gena,
04:05
And now the boysdječaci and the girlsdjevojke get them.
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a djevojčice i dječaci ih nasljeđuju.
04:07
So I think after severalnekoliko generationsgeneracije,
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I evo jedne ideje - nakon nekoliko generacija
04:09
and here is the ideaideja, we really have a tinderboxterorista.
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dobijete potencijalnu “atomsku bombu“.
04:12
So that was the ideaideja.
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I tako sam ja imao tu ideju,
04:14
But then my mothermajka said to me, "I hearčuti you've been going around talkingkoji govori
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ali onda mi je majka rekla, ˝Čujem da pričaš uokolo
04:16
about psychopathicpsihijatrijski killersubojice.
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o psihopatskim ubojicama.
04:19
And you're talkingkoji govori as if you come from a normalnormalan familyobitelj."
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Govoriš kao da ti potičeš iz normalne obitelji.˝
04:22
I said, "What the hellpakao are you talkingkoji govori about?"
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A ja sam na to odgovorio, „Što to dovraga pričaš?“
04:24
She then told me about our ownvlastiti familyobitelj treedrvo.
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Onda mi je ispričala o našem obiteljskom stablu.
04:27
Now she blamedkrivi this on my father'soca sidestrana, of coursenaravno.
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Naravno, okrivila je očevu stranu,
04:29
This was one of these casesslučajevi, because she has no violencenasilje in her backgroundpozadina,
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jer ona nije imala nasilnu prošlost.
04:33
but my fatherotac did.
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Ali, moj otac jest.
04:35
Well she said, "There is good newsvijesti and badloše newsvijesti.
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Rekla je, „Imam dobre i loše vijesti.
04:37
One of your cousinsrođaci is EzraEzra CornellCornell, founderosnivač of CornellCornell universitysveučilište.
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Jedan od tvojih rođaka je Ezra Cornell, osnivač Sveučilišta Cornell.
04:40
But the badloše newsvijesti is that your cousinrođak is alsotakođer LizzieLizzie BordenBorden.
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Ali loše vijesti su to da je tvoja rođakinja i Lizzi Borden.
04:43
Now I said, "Okay, so what? We have LizzieLizzie."
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Ja sam odgovorio, „Ok, pa što? Znamo za Lizzi.“
04:50
She goeside, "No it getsdobiva worsegore, readčitati this bookrezervirati."
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Ona je nastavila, „Ne, pročitaj knjigu, postaje gore.“
04:52
And here is this "KilledUbio StrangelyČudno," and it's this historicalpovijesni bookrezervirati.
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I evo je, „Ubijena na čudan način“ i to je ta povijesna knjiga.
04:54
And the first murderubiti
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I prvo ubojstvo
04:56
of a mothermajka by a sonsin
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majke od strane sina,
04:58
was my great-great-great-great-great-great-grandfatherGreat-Great-Great-Great-Great-Great-Grandfather.
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bilo je ono mojeg pra-pra-pra-pra-pra-pra-pradjeda.
05:01
Okay, so that's the first casespis of matricidenatjera da pokuša pobačaj.
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Ok, dakle to je prvi takav slučaj.
05:04
And that bookrezervirati is very interestingzanimljiv. Because it's about witchvještica trialsispitivanja,
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I knjiga je vrlo zanimljiva, jer govori i o suđenju vješticama
05:07
and how people thought back then.
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i ljudskim razmišljanjima u to doba.
05:09
But it doesn't stop there.
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Ali tu nije kraj.
05:11
There were sevensedam more menmuškarci, on my father'soca sidestrana,
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Sedmorica muškaraca, s očeve strane,
05:14
startingpolazeći then, CornellsCornells, that were all murderersubojice.
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iz obitelji Cornell, svi su bili ubojice.
05:18
Okay, now this givesdaje one a little pausepauza.
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Ok, ovo zaslužuje malu pauzu.
05:21
(LaughterSmijeh)
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(Smijeh)
05:23
Because my fatherotac himselfsam,
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Zato što su moj otac
05:25
and my threetri unclesstričevi, in WorldSvijet WarRat IIII,
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i trojica stričeva, u Drugom svjetskom ratu,
05:27
were all conscientioussavjestan objectorsprigovora, all pussycatsmačkice.
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bili protiv rata, mamine mazice.
05:30
But everysvaki oncejednom in a while, like LizzieLizzie BordenBorden, like threetri timesputa a centurystoljeće,
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Ali svako malo, npr. tri puta u stoljeću, nađe se slučaj kao s Lizzie Borden,
05:32
and we're kindljubazan of dueuslijed.
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i onda smo mi „kvit.“
05:34
(LaughterSmijeh)
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(Smijeh)
05:37
So the moralmoralan of the storypriča is:
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Pouka ove priče je:
05:39
people in glassstaklo houseskuća shouldn'tne treba throwbacanje stoneskamenje.
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ljudi u staklenim kućama ne bi trebali bacati kamenje.
05:41
But more likelyVjerojatno is this.
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Ali, više je onih koji to rade.
05:44
(LaughterSmijeh)
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(Smijeh)
05:48
And we had to take actionakcijski. Now our kidsdjeca foundpronađeno out about it.
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I mi moramo djelovati, jer sada su naša djeca saznala za to,
05:51
And they all seemedčinilo se to be OK.
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i svi se čine kao da im je to u redu.
05:53
But our grandkidsunuke are going to be kindljubazan of concernedzabrinut here.
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Ali naši unuci će biti zabrinuti.
05:56
So what we'veimamo doneučinio is I've startedpočeo to do PETLJUBIMAC scansskenira
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Stoga sam napravio PET sken
05:59
of everybodysvi in the familyobitelj.
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cijele obitelji.
06:01
(LaughterSmijeh)
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(Smijeh)
06:02
We startedpočeo to do PETLJUBIMAC scansskenira, EEGsJaja koja and geneticgenetski analysisanaliza
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Počeli smo sa PET skenovima, EEG-om i genetičkim analizama
06:05
to see where the badloše newsvijesti is.
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da utvrdimo gdje je centar loših vijesti.
06:07
Now the only personosoba -- it turnsokreti out
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Ispitivao sam
06:09
one sonsin and one daughterkći, siblingsbraća i sestre,
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sina i kćerku, braću,
06:12
didn't get alonguz and theirnjihov patternsobrasci are exactlytočno the sameisti.
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nisu se slagali, iako su im uzorci isti.
06:14
They have the sameisti brainmozak, and the sameisti EEGEEG.
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Imaju isti mozak, isti EEG.
06:17
And now they are closeblizu as can be.
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Sada su najbliži što mogu biti.
06:20
But there's gonna be badloše newsvijesti somewherenegdje.
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Negdje će biti loših vijesti,
06:22
And we don't know where it's going to poppop up.
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a mi ne znamo gdje one mogu buknuti.
06:24
So that's my talk.
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To bi bio moj govor.
06:26
(LaughterSmijeh)
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(Smijeh)
Translated by Senzos Osijek
Reviewed by Tilen Pigac - EFZG

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ABOUT THE SPEAKER
Jim Fallon - Neurobiologist
Sloan Scholar, Fulbright Fellow, Professor Emeritus of Neuroscience, Jim Fallon looks at the way nature and nurture intermingle to wire up the human brain.

Why you should listen

Jim Fallon has taught neuroscience and psychiatry grand rounds at the University of California Irvine for thirty-five years. Through research he explores the way genetic and perinatal environmental factors affect the way the brain gets built -- and then how an individual's experience further shapes his or her development. He lectures and writes on creativity, consciousness and culture, and has made key contributions to our understanding of adult stems and stroke, schizophrenia, Parkinson's disease and Alzheimer's disease.

Only lately has Fallon turned his research toward the subject of psychopaths -- particularly those who kill. With PET scans and EEGs, he's beginning to uncover the deep, underlying traits that make people violent and murderous. In his talk at TEDDIY at TED@PalmSprings, he shared a surprise discovery about his own family that prompted him to bring his work home.

Watch his followup talk from The Moth at the 2011 World Science Festival >>

More profile about the speaker
Jim Fallon | Speaker | TED.com

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