Edsel Salvaña: The dangerous evolution of HIV
Едсел Салвања (Edsel Salvaña): Опасна еволуција ХИВ-а
TED Fellow Edsel Salvaña studies the genetics of HIV, and he worries that we are just a few mutations away from the next deadly pandemic. Full bio
Double-click the English transcript below to play the video.
and bluest skies on the planet.
и најведријих неба на планети.
HIV epidemics in the world.
која се најбрже шири на свету.
as if we are just a late bloomer.
епидемија само касно захватила.
for our current epidemic
a global resurgence of HIV.
на повратак ХИВ-а широм света.
continue to drop in the world,
број нових случајева ХИВ-а
and resistant viruses arrive.
агресивнијих и отпорнијих вируса.
into a new and different virus
у нови и другачији вирус
we've made in reversing the epidemic,
који смо постигли у заустављању епидемије,
viral mutations away from disaster.
мутација вируса удаљени од катастрофе.
in which HIV transforms itself
на који се ХИВ трансформише
among humans of different races
између људи различитих раса
is only 0.1 percent.
and rhesus macaques,
и макаки мајмуна,
between HIV subtypes
између подврста ХИВ-а
between an infecting mother virus
који је изазвао заразу
as much as five percent.
giving birth to a chimpanzee,
током свог живота роди шимпанзу,
within its lifetime.
being discovered regularly.
редовно откривају.
is almost all of one subtype:
углавном је из једног подтипа:
and do to treat HIV
и предузимамо да лечимо ХИВ
accounts for 12 percent
of cases of HIV in the world.
genetic difference
to become drug-resistant
постати отпорни на лекове
of HIV cases in the Philippines
ХИВ-а на Филипинима
from the Western subtype B
Southeast Asian subtype AE.
из југоисточне Азије.
и болеснијим пацијентима
in developed countries,
Canada and the United States.
Канаду и Сједињене Државе.
explosion of cases in these countries.
у броју оболелих у овим земљама.
од ХИВ-а смањује,
it can come right back.
може се одмах вратити.
malaria was on the ropes.
је била скоро искорењена.
stopped paying attention.
да обраћају пажњу.
of drug-resistant malaria.
повратак маларије
that we think we've figured out,
који мислимо да смо прокљувили,
and highly unique viruses,
који се брзо развијају
the next deadly epidemic.
следећу смртоносну епидемију.
more powerful and new tools
the next deadly HIV strain,
следеће смртоносне врсте ХИВ-а,
with urgent research
хитним истраживањима
of non-B subtypes.
подтипова ХИВ-а који нису подтип Б.
и агенције за финансирање
of an AIDS-free generation.
у којој сида неће постојати.
ABOUT THE SPEAKER
Edsel Salvaña - Infectious disease specialist, molecular epidemiologistTED Fellow Edsel Salvaña studies the genetics of HIV, and he worries that we are just a few mutations away from the next deadly pandemic.
Why you should listen
Dr. Edsel Salvaña discovered that the driving force behind a new AIDS epidemic in the Philippines is the entry and spread of a deadlier strain of HIV -- a situation that can easily occur anywhere in the world.
Salvaña is an infectious disease specialist, molecular epidemiologist and is the director of the Institute of Molecular Biology and Biotechnology at the National Institutes of Health at the University of the Philippines in Manila. He is using next-generation sequencing and other cutting-edge genetic tools to study HIV viral diversity and superinfection. He is looking at how HIV develops drug resistance to better understand why his country suddenly has the fastest growing HIV epidemic in Asia; and why HIV treatment that works well in developed countries is failing on emerging HIV strains in the Philippines and resource-limited settings. He trains doctors in infectious diseases, and supervises the care of several thousand HIV patients at the Philippine General Hospital. He has been a national force in the formulation of HIV treatment guidelines, campaigning against stigma, and raising awareness.
Salvaña's advocacy work has been featured in Science, and he has been recognized with numerous national and international awards including the "Ten Outstanding Young Persons of the World" from JCI International and the Young Physician Leader Award from the Interacademy Medical Panel of the World Academy of Sciences. He was named a TED Fellow in 2017.
Edsel Salvaña | Speaker | TED.com