TED2008
Dean Ornish: Your genes are not your fate
Dean Ornish - Genele nu reprezinta destinul nostru
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Dean Ornish impartaseste noi cercetari care arata ca adoptarea unui stil de viata mai sanatos, poate afecta o persoana chiar la nivel genetic. De exemplu, atunci cand traiesti mai sanatos, mananci mai bine, faci sport si iubesti mai mult, celulele creierului tau cresc in numar.
Dean Ornish - Physician, author
Dean Ornish is a clinical professor at UCSF and founder of the Preventive Medicine Research Institute. He's a leading expert on fighting illness -- particularly heart disease with dietary and lifestyle changes. Full bio
Dean Ornish is a clinical professor at UCSF and founder of the Preventive Medicine Research Institute. He's a leading expert on fighting illness -- particularly heart disease with dietary and lifestyle changes. Full bio
Double-click the English transcript below to play the video.
00:12
One way to change our genes is to make new ones,
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Un mod de a ne schimba genele, este de a crea altele noi,
00:14
as Craig Venter has so elegantly shown.
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asa cum Craig Venter ne-a aratat atat de elegant.
00:16
Another is to change our lifestyles.
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Un alt mod este de a ne schimba stilul de viata.
00:19
And what we're learning is how powerful and dynamic these changes can be,
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Si astfel aflam cat de dinamice si puternice pot fi aceste schimbari,
00:23
that you don't have to wait very long to see the benefits.
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incat nu trebuie sa asteptam prea mult pentru a vedea beneficiile.
00:26
When you eat healthier, manage stress, exercise and love more,
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Cand mananci mai sanatos, reduci stresul, faci sport si iubesti mai mult,
00:31
your brain actually gets more blood flow and more oxygen.
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creierul tau primeste un flux mai mare de sange si mai mult oxigen.
00:33
But more than that, your brain gets measurably bigger.
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Mai mult decat atat, creierul tau se mareste considerabil.
00:36
Things that were thought impossible just a few years ago
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Lucruri considerate imposibile cu cativa ani in urma
00:38
can actually be measured now.
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pot fi masurate astazi.
00:40
This was figured out by Robin Williams
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Acest lucru a fost realizat de Robin Williams
00:43
a few years before the rest of us.
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cu cativa ani inaintea noastra.
00:45
Now, there's some things that you can do
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Acum, sunt cateva lucruri pe care le poti face
00:47
to make your brain grow new brain cells.
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pentru a stimula creierul sa produca noi celule neuronale
00:50
Some of my favorite things, like chocolate and tea, blueberries,
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Cateva din favoritele mele, precum ciocolata, ceaiul, afinele,
00:52
alcohol in moderation, stress management
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alcoolul in moderatie, managementul stresului
00:56
and cannabinoids found in marijuana.
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si canabanoidele ce se gasesc in marijuana.
00:58
I'm just the messenger.
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Eu sunt doar mesagerul.
01:01
(Laughter)
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(Rasete)
01:04
What were we just talking about?
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Despre ce vorbeam?
01:07
(Laughter)
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(Rasete)
01:09
And other things that can make it worse,
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Iar alte lucruri pot accelera procesul,
01:11
that can cause you to lose brain cells.
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de distrugere a celulelor creierului.
01:13
The usual suspects, like saturated fat and sugar,
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Suspectii obisnuiti, precum grasimile saturate si zaharul,
01:16
nicotine, opiates, cocaine, too much alcohol and chronic stress.
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nicotina, opiumul, cocaina, prea mult alcool si stresul cronic.
01:20
Your skin gets more blood flow when you change your lifestyle,
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Pielea ta primeste un flux mai mare de sange atunci cand iti schimbi stilul de viata,
01:23
so you age less quickly. Your skin doesn't wrinkle as much.
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deci, imbatranesti mai lent si nu faci atat de multe riduri.
01:26
Your heart gets more blood flow.
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Inima ta primeste un flux mai mare de sange.
01:28
We've shown that you can actually reverse heart disease.
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S-a aratat deja ca poti reversa o boala cardiaca.
01:30
That these clogged arteries that you see on the upper left,
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Ca aceste artere obstructionate pe care le vedeti in stanga-sus,
01:33
after only a year become measurably less clogged.
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dupa doar un an, devin masurabil, mai putin obstructionate.
01:35
And the cardiac PET scan shown on the lower left,
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Si in PET-scan-ul cardiac, aratat in stanga-jos,
01:37
the blue means no blood flow.
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"albastru" semnifica lipsa fluxului sangvin.
01:39
A year later -- orange and white is maximum blood flow.
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Un an mai tarziu -- "portocaliu" si "alb" indica maximum de flux sangvin.
01:42
We've shown you may be able to stop and reverse the progression
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Am aratat ca poti stopa si chiar reversa progresul
01:45
of early prostate cancer and, by extension, breast cancer,
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cancerului de prostata timpuriu si, deasemeni, cancerului de san,
01:47
simply by making these changes.
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prin simpla adoptare a acestor schimbari.
01:49
We've found that tumor growth in vitro was inhibited
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Am descoperit ca tumora crescuta in vitro a fost stopata
01:52
70 percent in the group that made these changes,
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70 procente in grupul care a aplicat aceste schimbari,
01:54
whereas only nine percent in the comparison group.
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in timp ce numai 9 procente in grupul de comparatie.
01:57
These differences were highly significant.
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Aceste diferente sunt foarte semnificative.
01:59
Even your sexual organs get more blood flow,
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Chiar si organele genitale primesc mai mult sange,
02:01
so you increase sexual potency.
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iar performanta sexuala creste.
02:03
One of the most effective anti-smoking ads was done
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Unul din cele mai eficiente clipuri anti-fumat a fost realizat
02:05
by the Department of Health Services,
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de Department of Health Services,
02:07
showing that nicotine, which constricts your arteries,
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aratand ca nicotina, care contracta arterele,
02:09
can cause a heart attack or a stroke,
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poate cauza un infarct sau un accident vascular,
02:11
but it also causes impotence.
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dar deasemeni produce impotenta.
02:13
Half of guys who smoke are impotent.
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Jumatate din barbatii care fumeaza sunt impotenti.
02:15
How sexy is that?
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Cat de sexy este asta?
02:16
Now we're also about to publish a study --
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Acum suntem pe cale de a publica un studiu --
02:18
the first study showing you can change gene expression in men with prostate cancer.
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care arata ca poti schimba comportamentul genelor la barbatii cu cancer de prostata.
02:21
This is what's called a heat map --
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Aceasta este o "harta termica"
02:23
and the different colors -- and along the side, on the right, are different genes.
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si diferitele culori din marginea dreapta, indica diferite gene.
02:26
And we found that over 500 genes were favorably changed --
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Si am descoperit ca peste 500 de gene s-au schimbat favorabil
02:29
in effect, turning on the good genes, the disease-preventing genes,
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si ca efect au activat "genele bune", acelea care previn bolile
02:32
turning off the disease-promoting genes.
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inhibandu-le pe cele care favorizeaza bolile.
02:36
And so these findings I think are really very powerful,
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Si cu aceste noi descoperiri cred ca putem
02:39
giving many people new hope and new choices.
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oferi multor oameni noi sperante si noi optiuni
02:41
And companies like Navigenics and DNA Direct and 23andMe,
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Si companii precum Navigenix, DNA Direct si23andMe,
02:46
that are giving you your genetic profiles,
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care realizeaza profile genetice,
02:49
are giving some people a sense of, "Gosh, well, what can I do about it?"
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dau oamenilor un sens de "Doamne, ce pot eu face?"
02:52
Well, our genes are not our fate, and if we make these changes --
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Ei bine, genele noastre nu reprezinta destinul nostru si daca facem aceste schimbari,
02:55
they're a predisposition -- but if we make bigger changes
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ele devin doar o predispozitie, dar, daca facem schimbari si mai mari
02:57
than we might have made otherwise,
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decat am fi facut anterior,
02:59
we can actually change how our genes are expressed.
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putem chiar schimba modul in care genele noastre se exprima.
03:02
Thank you.
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Va multumesc.
03:03
(Applause)
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(Aplauze)
ABOUT THE SPEAKER
Dean Ornish - Physician, authorDean Ornish is a clinical professor at UCSF and founder of the Preventive Medicine Research Institute. He's a leading expert on fighting illness -- particularly heart disease with dietary and lifestyle changes.
Why you should listen
Dr. Dean Ornish wants you to live longer, and have more fun while you're at it. He's one of the leading voices in the medical community promoting a balanced, holistic approach to health, and proving that it works. The author of Eat More, Weigh Less and several other best-selling books, Ornish is best known for his lifestyle-based approach to fighting heart disease.
His research at the Preventive Medicine Research Institute (the nonprofit he founded) clinically demonstrated that cardiovascular illnesses -- and, most recently prostate cancer -- can be treated and even reversed through diet and exercise. These findings (once thought to be physiologically implausible) have been widely chronicled in the US media, including Newsweek, for which Ornish writes a column. The fifty-something physician, who's received many honors and awards, was chosen by LIFE Magazine as one of the most influential members of his generation. Among his many pursuits, Ornish is now working with food corporations to help stop America's obesity pandemic from spreading around the globe.
Dean Ornish | Speaker | TED.com