TED2008
Dean Ornish: Your genes are not your fate
Din Orniš kaže da vaši geni nisu vaša sudbina
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Din Orniš (Dean Ornish) deli istraživanje koje pokazuje kako usvajanje navika zdravog životnog stila može da utiče na osobu na nivou gena. Na primer, kaže, kada živite zdravije, jedete bolje, vežbate i volite više, vaše moždane ćelije se zapravo umnožavaju.
Dean Ornish - Physician, author
Dean Ornish is a clinical professor at UCSF and founder of the Preventive Medicine Research Institute. He's a leading expert on fighting illness -- particularly heart disease with dietary and lifestyle changes. Full bio
Dean Ornish is a clinical professor at UCSF and founder of the Preventive Medicine Research Institute. He's a leading expert on fighting illness -- particularly heart disease with dietary and lifestyle changes. Full bio
Double-click the English transcript below to play the video.
00:12
One way to change our genes is to make new ones,
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Jedan način da promenimo naše gene jeste da napravimo nove,
00:14
as Craig Venter has so elegantly shown.
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kao što Kreg Venter elegantno pokazao.
00:16
Another is to change our lifestyles.
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Drugi je da promenimo način života.
00:19
And what we're learning is how powerful and dynamic these changes can be,
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Ono što saznajemo je koliko moćne i dinamične te promene mogu biti,
00:23
that you don't have to wait very long to see the benefits.
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da ne morate dugo čekati da vidite dobrobiti.
00:26
When you eat healthier, manage stress, exercise and love more,
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Kada jedete zdravije, upravljate stresom, vežbate i volite više,
00:31
your brain actually gets more blood flow and more oxygen.
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protok krvi u vašem mozgu je veći i on dobija više kiseonika.
00:33
But more than that, your brain gets measurably bigger.
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Ali i više od toga, mozak vam postaje vidno veći.
00:36
Things that were thought impossible just a few years ago
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Stvari za koje smo samo pre nekoliko godina mislili da su nemoguće,
00:38
can actually be measured now.
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sada se zapravo mogu izmeriti.
00:40
This was figured out by Robin Williams
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Ovo je Robin Vilijams shvatio
00:43
a few years before the rest of us.
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nekoliko godina pre nas ostalih.
00:45
Now, there's some things that you can do
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Sad, postoje neke stvari koje možete uraditi
00:47
to make your brain grow new brain cells.
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da bi vaš mozak proizvodio nove moždane ćelije.
00:50
Some of my favorite things, like chocolate and tea, blueberries,
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Neke od mojih omiljenih stvari, čokolada i čaj, borovnice,
00:52
alcohol in moderation, stress management
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alkohol u umerenim količinama, upravljanje stresom
00:56
and cannabinoids found in marijuana.
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i kanabinoidi nađeni u marihuani.
00:58
I'm just the messenger.
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Ja samo prenosim poruku.
01:01
(Laughter)
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(smeh)
01:04
What were we just talking about?
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O čemu smo ono pričali?
01:07
(Laughter)
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(smeh)
01:09
And other things that can make it worse,
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I ostale stvari koje mogu pogoršati,
01:11
that can cause you to lose brain cells.
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zbog kojih možete izgubiti moždane ćelije.
01:13
The usual suspects, like saturated fat and sugar,
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Dežurni krivci, kao zasićene masti i šećer,
01:16
nicotine, opiates, cocaine, too much alcohol and chronic stress.
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nikotin, opijati, kokain, previše alkohola i hroničan stres.
01:20
Your skin gets more blood flow when you change your lifestyle,
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Vaša koža ima veći protok krvi kada promenite svoje navike,
01:23
so you age less quickly. Your skin doesn't wrinkle as much.
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tako da starite sporije, koža vam se ne bora toliko.
01:26
Your heart gets more blood flow.
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Srce vam dobija veći protok krvi.
01:28
We've shown that you can actually reverse heart disease.
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Pokazali smo da stvarno možete preokrenuti srčane bolesti.
01:30
That these clogged arteries that you see on the upper left,
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Da ove začepljene arterije koje vidite gore levo,
01:33
after only a year become measurably less clogged.
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posle samo godinu dana postaju vidljivo manje začepljene.
01:35
And the cardiac PET scan shown on the lower left,
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A na snimku srca sa PET skenera dole levo,
01:37
the blue means no blood flow.
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plavo znači da nema protoka krvi.
01:39
A year later -- orange and white is maximum blood flow.
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Godinu dana kasnije - narandžasto i belo je maksimalni protok krvi.
01:42
We've shown you may be able to stop and reverse the progression
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Pokazali smo da je moguće da zaustavite i vratite unazad napredak
01:45
of early prostate cancer and, by extension, breast cancer,
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ranog raka prostate i raka dojke,
01:47
simply by making these changes.
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samo pravljenjem ovih promena.
01:49
We've found that tumor growth in vitro was inhibited
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Dokazali smo da je rast in vitro tumora zaustavljen
01:52
70 percent in the group that made these changes,
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70% u grupi koja je napravila ove promene,
01:54
whereas only nine percent in the comparison group.
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dok je smanjen samo 9% u kontrolnoj grupi.
01:57
These differences were highly significant.
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Ove razlike su veoma značajne.
01:59
Even your sexual organs get more blood flow,
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Čak i vaši seksualni organi dobijaju više krvi,
02:01
so you increase sexual potency.
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tako da vam se povećava seksualna moć.
02:03
One of the most effective anti-smoking ads was done
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Ministarstvo zdravlja je napravilo
02:05
by the Department of Health Services,
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jednu od najučinkovitijih reklama protiv pušenja,
02:07
showing that nicotine, which constricts your arteries,
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koja pokazuje da nikotin, koji steže vaše arterije,
02:09
can cause a heart attack or a stroke,
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može uzrokovati srčani ili moždani udar,
02:11
but it also causes impotence.
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ali isto tako uzrokuje impotenciju.
02:13
Half of guys who smoke are impotent.
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Polovina momaka koji puše su impotentni.
02:15
How sexy is that?
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Kako je to seksi?
02:16
Now we're also about to publish a study --
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Takođe ćemo uskoro objaviti studiju -
02:18
the first study showing you can change gene expression in men with prostate cancer.
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studiju koja pokazuje da možete promeniti izraz gena kod muškaraca sa rakom prostate.
02:21
This is what's called a heat map --
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Ovo se zove toplotna mapa
02:23
and the different colors -- and along the side, on the right, are different genes.
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i različite boje i sa desne strane su različiti geni.
02:26
And we found that over 500 genes were favorably changed --
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Našli smo da je preko 500 gena povoljno promenjeno
02:29
in effect, turning on the good genes, the disease-preventing genes,
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i tako uključuju dobre gene koji sprečavaju bolest,
02:32
turning off the disease-promoting genes.
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a isključuju gene koji prenose bolest.
02:36
And so these findings I think are really very powerful,
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Mislim da su ti nalazi stvarno veoma moćni
02:39
giving many people new hope and new choices.
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i daju novu nadu i nove izbore mnogim ljudima.
02:41
And companies like Navigenics and DNA Direct and 23andMe,
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I kompanije kao "Navigenix" i "DNA Direct" i "23andMe"
02:46
that are giving you your genetic profiles,
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koje vam daju vaše genetske profile,
02:49
are giving some people a sense of, "Gosh, well, what can I do about it?"
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nekim ljudima daju osećaj "Bogo, pa šta ja mogu tu da uradim?"
02:52
Well, our genes are not our fate, and if we make these changes --
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Pa, naši geni nisu naša sudbina i ako napravimo te promene -
02:55
they're a predisposition -- but if we make bigger changes
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oni su predispozicija, ali ako napravimo veće promene
02:57
than we might have made otherwise,
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nego što smo mogli inače,
02:59
we can actually change how our genes are expressed.
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stvarno možemo promeniti način ispoljavanja naših gena.
03:02
Thank you.
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Hvala vam.
03:03
(Applause)
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(aplauz)
ABOUT THE SPEAKER
Dean Ornish - Physician, authorDean Ornish is a clinical professor at UCSF and founder of the Preventive Medicine Research Institute. He's a leading expert on fighting illness -- particularly heart disease with dietary and lifestyle changes.
Why you should listen
Dr. Dean Ornish wants you to live longer, and have more fun while you're at it. He's one of the leading voices in the medical community promoting a balanced, holistic approach to health, and proving that it works. The author of Eat More, Weigh Less and several other best-selling books, Ornish is best known for his lifestyle-based approach to fighting heart disease.
His research at the Preventive Medicine Research Institute (the nonprofit he founded) clinically demonstrated that cardiovascular illnesses -- and, most recently prostate cancer -- can be treated and even reversed through diet and exercise. These findings (once thought to be physiologically implausible) have been widely chronicled in the US media, including Newsweek, for which Ornish writes a column. The fifty-something physician, who's received many honors and awards, was chosen by LIFE Magazine as one of the most influential members of his generation. Among his many pursuits, Ornish is now working with food corporations to help stop America's obesity pandemic from spreading around the globe.
Dean Ornish | Speaker | TED.com