TED2008
Dean Ornish: Your genes are not your fate
Dean Ornish geningiz taqdiriningiz emas deb aytadi
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Dean Ornish biz bilan baham ko'rayotgan ilmiy ish natijalari, sog'lom turmush tarzini o'zlashtirish odamga genetik darajada ta'sir qila oladi.
Dean Ornish - Physician, author
Dean Ornish is a clinical professor at UCSF and founder of the Preventive Medicine Research Institute. He's a leading expert on fighting illness -- particularly heart disease with dietary and lifestyle changes. Full bio
Dean Ornish is a clinical professor at UCSF and founder of the Preventive Medicine Research Institute. He's a leading expert on fighting illness -- particularly heart disease with dietary and lifestyle changes. Full bio
Double-click the English transcript below to play the video.
00:12
One way to change our genes is to make new ones,
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Genlarimizni o'zgartirishning bir usuli yangi gen yaratish,
00:14
as Craig Venter has so elegantly shown.
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buni Craig Venter yaxshilab ko'rsatdi.
00:16
Another is to change our lifestyles.
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Boshqa usuli esa turmush tarzimizni o'zgartirish.
00:19
And what we're learning is how powerful and dynamic these changes can be,
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Biz o'rganayotgan narsa bu o'zgarishlar qanchalik kuchga ega ekanligidir,
00:23
that you don't have to wait very long to see the benefits.
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yani, foydali natijalarni ko'rish uchun siz uzoq kutib o'tirmaysiz.
00:26
When you eat healthier, manage stress, exercise and love more,
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Qachonki sog'lom yesangiz, g'ayg'urish va stressni boshqara olsangiz, ko'proq sevsangiz
00:31
your brain actually gets more blood flow and more oxygen.
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miyangiz chindan ham ko'proq kislorod va qon aylanishini yaxshilaydi.
00:33
But more than that, your brain gets measurably bigger.
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Undan ham ko'proq, miyangiz o'lchami oshadi.
00:36
Things that were thought impossible just a few years ago
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Bir necha yil avval mumkin emas deb o'ylagan narsalar
00:38
can actually be measured now.
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endi hozir o'lchana oladi.
00:40
This was figured out by Robin Williams
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Buni Robin Williams bilib bo'lgan edi
00:43
a few years before the rest of us.
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bizdan burun bir necha yil avval.
00:45
Now, there's some things that you can do
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Endi, siz qilsangiz bo'ladigan bir qator narsalar bor
00:47
to make your brain grow new brain cells.
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yani miyangizni yangi hujayralar o'stirish uchun.
00:50
Some of my favorite things, like chocolate and tea, blueberries,
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Men yaxshi ko'rgan narsalardan, masalan shokolod, choy, smorodina
00:52
alcohol in moderation, stress management
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meyorida biroz alkogol, stress boshqarish
00:56
and cannabinoids found in marijuana.
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va Marihuanada topilgan kanaboidlar.
00:58
I'm just the messenger.
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Men shunchaki aytayapman .
01:01
(Laughter)
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(Kulgi)
01:04
What were we just talking about?
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Nima haqida gapirayotgan edik?
01:07
(Laughter)
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(Kulgi)
01:09
And other things that can make it worse,
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Ba'zi narsalar vaziyatni yomonlashtiradi
01:11
that can cause you to lose brain cells.
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miya hujayralarini nobud qila oladi.
01:13
The usual suspects, like saturated fat and sugar,
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Odatdagi ayblanuvchilar, to'yingan yog' va shakar,
01:16
nicotine, opiates, cocaine, too much alcohol and chronic stress.
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nikotin, nasha, kokain,ortiqcha alkogol va uzoq muddatga cho'zilgan stress, og'ir ish.
01:20
Your skin gets more blood flow when you change your lifestyle,
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Siz turmush tarszingizni o'zgartirganda, terisingizda yaxshi qon aylanadi,
01:23
so you age less quickly. Your skin doesn't wrinkle as much.
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sekinroq qariysiz, teringizga unha ko'p ajin tushmaydi.
01:26
Your heart gets more blood flow.
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Yuragingizda qon aylanish yaxshilanadi.
01:28
We've shown that you can actually reverse heart disease.
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Biz yurak kasalliklarini orqaga qaytarish mumkinligi ko'rsata oldik.
01:30
That these clogged arteries that you see on the upper left,
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Mana bu bekilib qolgan arteriyalarni ko'rayapsizmi chap yuqori qismda,
01:33
after only a year become measurably less clogged.
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atigi bir yildan keyingina arteriya to'lib qolishi ancha kamaygan.
01:35
And the cardiac PET scan shown on the lower left,
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Yurak PET skanirovaniya qilganda pastki chap qismda
01:37
the blue means no blood flow.
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ko'k rang qon aylanmayapti degani.
01:39
A year later -- orange and white is maximum blood flow.
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Bir yildan so'ng- to'q sarir va oq rangda eng katta maximum qon aylaniyishi.
01:42
We've shown you may be able to stop and reverse the progression
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Biz sizga ko'rsatgandek, kasallikni to'xtatish va uni orqaga qaytarish mumkin,
01:45
of early prostate cancer and, by extension, breast cancer,
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erta prostata raki, va ko'krak rakini orqaga qaytarish mumkin
01:47
simply by making these changes.
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shunchaki shunday kichik bir o'zgartishlar kiritish bilan.
01:49
We've found that tumor growth in vitro was inhibited
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Laboratoriyda o'smaning o'sishi 70% ga to'xtatilgan
01:52
70 percent in the group that made these changes,
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qachonki biz bir guruhga o'zgartirish kiritganda
01:54
whereas only nine percent in the comparison group.
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va o'zgartirihs kiritmaganda faqat 9% gina to'xtatilgan.
01:57
These differences were highly significant.
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Bu farqlar juda katta ahamiyatga ega.
01:59
Even your sexual organs get more blood flow,
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Hatto jinsiy organlarda ham yaxshi qon aylanadi.
02:01
so you increase sexual potency.
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va jinsiy potentsial oshadi.
02:03
One of the most effective anti-smoking ads was done
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chekishga qarshi qilingan reklamalarning eng foydalisi
02:05
by the Department of Health Services,
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Sog'liqni saqlash xizmati tomonidan,
02:07
showing that nicotine, which constricts your arteries,
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shuni ko'rsatadiki, nikotin arteriya qon tomirlarini toraytiradi
02:09
can cause a heart attack or a stroke,
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va yurak huruji va insult keltirib chiqaradi,
02:11
but it also causes impotence.
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lekin yana u jinsiy impotentsiyaga olib keladi.
02:13
Half of guys who smoke are impotent.
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Chekuvchi erkaklarning yarimi nasl qoldirishga yaroqsiz, impotetentdir.
02:15
How sexy is that?
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Qani aytingchi bu qanchalik et'tiborga loyiq?
02:16
Now we're also about to publish a study --
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Endi biz ilmiy ishni nashr qilmoqchimiz-
02:18
the first study showing you can change gene expression in men with prostate cancer.
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bu erkaklarda prostatta rakidagi genlarning aks ettishini o'zgartiirsh haqida.
02:21
This is what's called a heat map --
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Bu issiq xarita deb nomlanadi
02:23
and the different colors -- and along the side, on the right, are different genes.
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har hil ranglar , va har hil genlar o'ng tomonda.
02:26
And we found that over 500 genes were favorably changed --
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Biz shuni topdikki 500 dna ortiq gen yaxhshi tomonga o'zgargan
02:29
in effect, turning on the good genes, the disease-preventing genes,
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yani yaxhsi genlar ishga tushgan, yani kasallikning oldini oluvchi genlar
02:32
turning off the disease-promoting genes.
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kasalik qo'zg'atuvchi genlarni "o'chirgan"
02:36
And so these findings I think are really very powerful,
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Menimcha bu natijalar juda muhim
02:39
giving many people new hope and new choices.
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va odamlarga yangi umid va tanlov beradi
02:41
And companies like Navigenics and DNA Direct and 23andMe,
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Navigenix va DNA direct va 23andME kabi kompaniyalar
02:46
that are giving you your genetic profiles,
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sizning genetic xaritalaringizni berayapti
02:49
are giving some people a sense of, "Gosh, well, what can I do about it?"
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va ba'zi odamlar " bu bilan nima qilaman?" deb aytadi.
02:52
Well, our genes are not our fate, and if we make these changes --
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Lekin, genlarimiz bizning taqdirimiz emas, agar biz o'zgarishlar kiritsak-
02:55
they're a predisposition -- but if we make bigger changes
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katta o'zgarishlar kiritsak
02:57
than we might have made otherwise,
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boshqa xato qilish o'rniga,
02:59
we can actually change how our genes are expressed.
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biz chindan ham genlarimizning qanday ishlashini o'zgartira olamiz.
03:02
Thank you.
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Rahmat.
03:03
(Applause)
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(Qarsaklar)
ABOUT THE SPEAKER
Dean Ornish - Physician, authorDean Ornish is a clinical professor at UCSF and founder of the Preventive Medicine Research Institute. He's a leading expert on fighting illness -- particularly heart disease with dietary and lifestyle changes.
Why you should listen
Dr. Dean Ornish wants you to live longer, and have more fun while you're at it. He's one of the leading voices in the medical community promoting a balanced, holistic approach to health, and proving that it works. The author of Eat More, Weigh Less and several other best-selling books, Ornish is best known for his lifestyle-based approach to fighting heart disease.
His research at the Preventive Medicine Research Institute (the nonprofit he founded) clinically demonstrated that cardiovascular illnesses -- and, most recently prostate cancer -- can be treated and even reversed through diet and exercise. These findings (once thought to be physiologically implausible) have been widely chronicled in the US media, including Newsweek, for which Ornish writes a column. The fifty-something physician, who's received many honors and awards, was chosen by LIFE Magazine as one of the most influential members of his generation. Among his many pursuits, Ornish is now working with food corporations to help stop America's obesity pandemic from spreading around the globe.
Dean Ornish | Speaker | TED.com