TED2008
Dean Ornish: Your genes are not your fate
Dean Ornish pravi, da naši geni niso naša usoda
Filmed:
Readability: 4.5
1,725,634 views
Dean Ornish o novi raziskavi, ki kaže, da zdrave življenjske navade vplivajo na človeka na genetski ravni. Če živimo bolj zdravo, bolje jemo, več telovadimo in ljubimo, se naše možganske celice povečajo.
Dean Ornish - Physician, author
Dean Ornish is a clinical professor at UCSF and founder of the Preventive Medicine Research Institute. He's a leading expert on fighting illness -- particularly heart disease with dietary and lifestyle changes. Full bio
Dean Ornish is a clinical professor at UCSF and founder of the Preventive Medicine Research Institute. He's a leading expert on fighting illness -- particularly heart disease with dietary and lifestyle changes. Full bio
Double-click the English transcript below to play the video.
00:12
One way to change our genes is to make new ones,
0
0
2000
Gene lahko spremenite tako, da naredite nove,
00:14
as Craig Venter has so elegantly shown.
1
2000
2000
kot nam je to lepo razložil Craig Venter.
00:16
Another is to change our lifestyles.
2
4000
3000
Lahko pa spremenite svoj življenjski slog.
00:19
And what we're learning is how powerful and dynamic these changes can be,
3
7000
4000
Odkrivamo, da so te spremembe res močne in silovite.
00:23
that you don't have to wait very long to see the benefits.
4
11000
3000
Koristi se hitro pokažejo.
00:26
When you eat healthier, manage stress, exercise and love more,
5
14000
5000
Z zdravo prehrano, manj stresa, več telovadbe in ljubezni
00:31
your brain actually gets more blood flow and more oxygen.
6
19000
2000
možgani dobijo več krvi in več kisika.
00:33
But more than that, your brain gets measurably bigger.
7
21000
3000
Poleg tega se možgani opazno povečajo.
00:36
Things that were thought impossible just a few years ago
8
24000
2000
Stvari, ki so se zdele nemogoče pred nekaj leti,
00:38
can actually be measured now.
9
26000
2000
lahko zdaj izmerimo.
00:40
This was figured out by Robin Williams
10
28000
3000
To je nekaj let pred nami
00:43
a few years before the rest of us.
11
31000
2000
ugotovil Robin Williams [v filmu Ga. Doubtfire].
00:45
Now, there's some things that you can do
12
33000
2000
Možganom lahko na več načinov pomagamo
00:47
to make your brain grow new brain cells.
13
35000
3000
ustvariti nove možganske celice.
00:50
Some of my favorite things, like chocolate and tea, blueberries,
14
38000
2000
Najraje imam čokolado, čaj, borovnice.
00:52
alcohol in moderation, stress management
15
40000
4000
Drugi dejavniki so alkohol v zmernih količinah, obvladovanje stresa
00:56
and cannabinoids found in marijuana.
16
44000
2000
in kanabinoidi v marihuani.
00:58
I'm just the messenger.
17
46000
2000
Samo podajam dognanja drugih.
01:01
(Laughter)
18
49000
3000
(smeh)
01:04
What were we just talking about?
19
52000
3000
O čem sem že govoril?
01:07
(Laughter)
20
55000
2000
(smeh)
01:09
And other things that can make it worse,
21
57000
2000
Poglejmo stvari, ki so za možgane slabe,
01:11
that can cause you to lose brain cells.
22
59000
2000
ki zmanjšujejo število možganskih celic.
01:13
The usual suspects, like saturated fat and sugar,
23
61000
3000
Znane razvade, denimo nasičene maščobe in sladkor,
01:16
nicotine, opiates, cocaine, too much alcohol and chronic stress.
24
64000
4000
nikotin, opiati, kokain, preveč alkohola in kroničen stres.
01:20
Your skin gets more blood flow when you change your lifestyle,
25
68000
3000
Z zdravim načinom življenja bo koža bolj prekrvavljena.
01:23
so you age less quickly. Your skin doesn't wrinkle as much.
26
71000
3000
Starali se boste se počasneje, gub bo manj.
01:26
Your heart gets more blood flow.
27
74000
2000
Prekrvavitev srca se bo izboljšala.
01:28
We've shown that you can actually reverse heart disease.
28
76000
2000
Lahko se izognete srčnim boleznim.
01:30
That these clogged arteries that you see on the upper left,
29
78000
3000
Zamašene arterije, ki jih vidite zgoraj levo,
01:33
after only a year become measurably less clogged.
30
81000
2000
so po samo enem letu postale bolj prehodne.
01:35
And the cardiac PET scan shown on the lower left,
31
83000
2000
To je pozitronska tomografija srca.
01:37
the blue means no blood flow.
32
85000
2000
Modra barva pomeni brez pretoka krvi.
01:39
A year later -- orange and white is maximum blood flow.
33
87000
3000
Po enem letu: oranžna in bela pomenita največji pretok krvi.
01:42
We've shown you may be able to stop and reverse the progression
34
90000
3000
Dokazali smo, da lahko ustavimo in deloma ozdravimo
01:45
of early prostate cancer and, by extension, breast cancer,
35
93000
2000
raka na prostati in raka na dojkah v začetni fazi, če uvedemo te spremembe.
01:47
simply by making these changes.
36
95000
2000
raka na prostati in raka na dojkah v začetni fazi, če uvedemo te spremembe.
01:49
We've found that tumor growth in vitro was inhibited
37
97000
3000
S poskusi na celicah smo dokazali, da se je rast tumorja
01:52
70 percent in the group that made these changes,
38
100000
2000
ustavila pri 70% ljudi, ki so spremenili življenje.
01:54
whereas only nine percent in the comparison group.
39
102000
3000
V kontrolni skupini je bil delež samo 9 %.
01:57
These differences were highly significant.
40
105000
2000
Te razlike so neverjetne.
01:59
Even your sexual organs get more blood flow,
41
107000
2000
Tudi spolni organi so bolj prekrvavljeni,
02:01
so you increase sexual potency.
42
109000
2000
kar krepi spolno potenco.
02:03
One of the most effective anti-smoking ads was done
43
111000
2000
Najboljšo protikadilsko kampanjo je pripravilo
02:05
by the Department of Health Services,
44
113000
2000
ameriško ministrstvo za zdravstvo.
02:07
showing that nicotine, which constricts your arteries,
45
115000
2000
Objavili so podatek, da nikotin skrči arterije,
02:09
can cause a heart attack or a stroke,
46
117000
2000
kar lahko povzroči srčno kap ali infarkt,
02:11
but it also causes impotence.
47
119000
2000
povzroča pa tudi impotenco.
02:13
Half of guys who smoke are impotent.
48
121000
2000
Polovica moških kadilcev je impotentna.
02:15
How sexy is that?
49
123000
1000
Se vam zdi to seksi?
02:16
Now we're also about to publish a study --
50
124000
2000
Naša nova raziskava kaže,
02:18
the first study showing you can change gene expression in men with prostate cancer.
51
126000
3000
da lahko spremenimo genski izraz pri moških z rakom na prostati.
02:21
This is what's called a heat map --
52
129000
2000
To je toplotni zemljevid.
02:23
and the different colors -- and along the side, on the right, are different genes.
53
131000
3000
Različne barve predstavljajo različne gene.
02:26
And we found that over 500 genes were favorably changed --
54
134000
3000
Odkrili smo, da se je 500 genov spremenilo na bolje.
02:29
in effect, turning on the good genes, the disease-preventing genes,
55
137000
3000
Vklopijo se dobri geni, ki preprečujejo bolezni,
02:32
turning off the disease-promoting genes.
56
140000
4000
in izklopijo geni, ki povečujejo možnost bolezni.
02:36
And so these findings I think are really very powerful,
57
144000
3000
Ti rezultati so zelo pomembni.
02:39
giving many people new hope and new choices.
58
147000
2000
Ljudem ponujajo novo upanje in nove možnosti.
02:41
And companies like Navigenics and DNA Direct and 23andMe,
59
149000
5000
Podjetja, kot so Navigenix, DNA Direct in 23andMe,
02:46
that are giving you your genetic profiles,
60
154000
3000
vam lahko izdelajo genetski profil.
02:49
are giving some people a sense of, "Gosh, well, what can I do about it?"
61
157000
3000
Ljudje se potem vprašajo – kaj lahko sploh še naredim?
02:52
Well, our genes are not our fate, and if we make these changes --
62
160000
3000
Naši geni niso naša usoda. S spremembo življenja ...
02:55
they're a predisposition -- but if we make bigger changes
63
163000
2000
Geni so le nagnjenost in če naredimo večje spremembe, kot bi jih sicer,
02:57
than we might have made otherwise,
64
165000
2000
Geni so le nagnjenost in če naredimo večje spremembe, kot bi jih sicer,
02:59
we can actually change how our genes are expressed.
65
167000
3000
lahko spremenimo izražanje naših genov.
03:02
Thank you.
66
170000
1000
Hvala.
03:03
(Applause)
67
171000
2000
(aplavz)
ABOUT THE SPEAKER
Dean Ornish - Physician, authorDean Ornish is a clinical professor at UCSF and founder of the Preventive Medicine Research Institute. He's a leading expert on fighting illness -- particularly heart disease with dietary and lifestyle changes.
Why you should listen
Dr. Dean Ornish wants you to live longer, and have more fun while you're at it. He's one of the leading voices in the medical community promoting a balanced, holistic approach to health, and proving that it works. The author of Eat More, Weigh Less and several other best-selling books, Ornish is best known for his lifestyle-based approach to fighting heart disease.
His research at the Preventive Medicine Research Institute (the nonprofit he founded) clinically demonstrated that cardiovascular illnesses -- and, most recently prostate cancer -- can be treated and even reversed through diet and exercise. These findings (once thought to be physiologically implausible) have been widely chronicled in the US media, including Newsweek, for which Ornish writes a column. The fifty-something physician, who's received many honors and awards, was chosen by LIFE Magazine as one of the most influential members of his generation. Among his many pursuits, Ornish is now working with food corporations to help stop America's obesity pandemic from spreading around the globe.
Dean Ornish | Speaker | TED.com