ABOUT THE SPEAKER
Dean Ornish - Physician, author
Dean Ornish is a clinical professor at UCSF and founder of the Preventive Medicine Research Institute. He's a leading expert on fighting illness -- particularly heart disease with dietary and lifestyle changes.

Why you should listen

Dr. Dean Ornish wants you to live longer, and have more fun while you're at it. He's one of the leading voices in the medical community promoting a balanced, holistic approach to health, and proving that it works. The author of Eat More, Weigh Less and several other best-selling books, Ornish is best known for his lifestyle-based approach to fighting heart disease.

His research at the Preventive Medicine Research Institute (the nonprofit he founded) clinically demonstrated that cardiovascular illnesses -- and, most recently prostate cancer -- can be treated and even reversed through diet and exercise. These findings (once thought to be physiologically implausible) have been widely chronicled in the US media, including Newsweek, for which Ornish writes a column. The fifty-something physician, who's received many honors and awards, was chosen by LIFE Magazine as one of the most influential members of his generation. Among his many pursuits, Ornish is now working with food corporations to help stop America's obesity pandemic from spreading around the globe.

More profile about the speaker
Dean Ornish | Speaker | TED.com
TED2008

Dean Ornish: Your genes are not your fate

Дин Орниш вели дека вашите гени не се и ваша судбина

Filmed:
1,725,634 views

Дин Орниш ги споделува новите истражувања кои покажуваат како присвојувањето на нов животен стил може да влијае врз една личност на генетско ниво. На пример, тој вели дека кога живеете здрав живот, јадете подобро, вежбате и сакате повеќе, вашите мочочни клетки се зголемуваат.
- Physician, author
Dean Ornish is a clinical professor at UCSF and founder of the Preventive Medicine Research Institute. He's a leading expert on fighting illness -- particularly heart disease with dietary and lifestyle changes. Full bio

Double-click the English transcript below to play the video.

00:12
One way to change our genes is to make new ones,
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Еден начин да ги промениме нашите гени е да создадеме нови,
00:14
as Craig Venter has so elegantly shown.
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како што Крег Вентер елегантно ни има покажано.
00:16
Another is to change our lifestyles.
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Друг начин е да го смениме нашиот животен стил.
00:19
And what we're learning is how powerful and dynamic these changes can be,
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Тоа што го учиме е колку само моќни и динамични овие промени можат да бидат,
00:23
that you don't have to wait very long to see the benefits.
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така што немора да се чека многу долго за да се видат придобивките.
00:26
When you eat healthier, manage stress, exercise and love more,
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Кога јадете поздраво, се справувате со стрес, вежбате и сакате повеќе,
00:31
your brain actually gets more blood flow and more oxygen.
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вашиот мозок всушност добива повеќе кислород.
00:33
But more than that, your brain gets measurably bigger.
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Но повеќе од тоа, вашиот мозок и мерно се зголемува.
00:36
Things that were thought impossible just a few years ago
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Нешта кои се сметаа за невозможни само пред неколку години
00:38
can actually be measured now.
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може сега да бидат измерени.
00:40
This was figured out by Robin Williams
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Ова беше осмислено од Робин Вилијамс
00:43
a few years before the rest of us.
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неколку години пред нас останатите.
00:45
Now, there's some things that you can do
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Сега, постојат неколку работи што може да се направат
00:47
to make your brain grow new brain cells.
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за мозокот да почне да расте нови мозочни клетки.
00:50
Some of my favorite things, like chocolate and tea, blueberries,
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Некои од моите омилени нешта, како чоколадо и чај, боровница,
00:52
alcohol in moderation, stress management
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алкохол во умерени количини, справување со стрес
00:56
and cannabinoids found in marijuana.
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и канабиноиди кои се наоѓаат во марихуана.
00:58
I'm just the messenger.
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Јас сум само курирот.
01:01
(Laughter)
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(Смеење)
01:04
What were we just talking about?
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Што точно ни беше муабетот?
01:07
(Laughter)
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(Смеење)
01:09
And other things that can make it worse,
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А некои нешта може да направат полошо,
01:11
that can cause you to lose brain cells.
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причинуваат губење на мозочни клетки.
01:13
The usual suspects, like saturated fat and sugar,
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Тоа се стандардните осомничени, како заситени масти и шеќер,
01:16
nicotine, opiates, cocaine, too much alcohol and chronic stress.
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никоти, опијати, кокаин, премногу алкохол и хроничен стрес.
01:20
Your skin gets more blood flow when you change your lifestyle,
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Вашата кожа добива поголем доток на крв кога го менувате животниот стил,
01:23
so you age less quickly. Your skin doesn't wrinkle as much.
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така што стареете побавно, и вашата кожа не се брчка така многу.
01:26
Your heart gets more blood flow.
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Вашето срце добива поголем доток на крв.
01:28
We've shown that you can actually reverse heart disease.
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Имаме покажано дека всушност може да се спречи срцево заболување.
01:30
That these clogged arteries that you see on the upper left,
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Дека овие затнати артерии кои ги гледате горе лево,
01:33
after only a year become measurably less clogged.
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по само една година може да бидат мерливо помалку затнати.
01:35
And the cardiac PET scan shown on the lower left,
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И на срцевата PET снимка прикажана долу лево,
01:37
the blue means no blood flow.
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синото означува непостоечки проток на крв.
01:39
A year later -- orange and white is maximum blood flow.
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Една година подоцна - во портокалово и бело е прикажан максималниот проток на крв.
01:42
We've shown you may be able to stop and reverse the progression
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Имаме покажано дека сте во можност да го запрете и свртите напредокот
01:45
of early prostate cancer and, by extension, breast cancer,
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на ран рак на простатата, и следствено рак на дојката,
01:47
simply by making these changes.
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само со правење на ваквите промени.
01:49
We've found that tumor growth in vitro was inhibited
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Откривме дека растењето на туморите ин витро беше намалено
01:52
70 percent in the group that made these changes,
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кај 70 проценти во групите кои ги направија овие промени,
01:54
whereas only nine percent in the comparison group.
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за разлика од девет проценти во споредбената група.
01:57
These differences were highly significant.
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Овие разлики се доста значајни.
01:59
Even your sexual organs get more blood flow,
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Дури и вашите сексуални органи добиваат поголем доток на крв,
02:01
so you increase sexual potency.
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така што ја зголемувате сексуалната потенција.
02:03
One of the most effective anti-smoking ads was done
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Една од најефективните реклами против пушење беше направена
02:05
by the Department of Health Services,
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од Одделот за Здравствени Услуги,
02:07
showing that nicotine, which constricts your arteries,
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покажувајќи дека никотинот, којшто ги стеснува вашите артерии,
02:09
can cause a heart attack or a stroke,
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може да причини срцев напад или удар,
02:11
but it also causes impotence.
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но може да причини и импотенција.
02:13
Half of guys who smoke are impotent.
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Половината од вас пушачите се импотентни.
02:15
How sexy is that?
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Колку секси е тоа?
02:16
Now we're also about to publish a study --
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Сега сме во тек на објавување на истражување --
02:18
the first study showing you can change gene expression in men with prostate cancer.
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истражување кое покажува дека може да се промени експресирањето на гени во мажи со рак на простата.
02:21
This is what's called a heat map --
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Ова се вика топлинска мапа
02:23
and the different colors -- and along the side, on the right, are different genes.
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со различни бои, а на десната страна надолж се различните гени.
02:26
And we found that over 500 genes were favorably changed --
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И откривме дека преку 500 гени беа склони кон промена
02:29
in effect, turning on the good genes, the disease-preventing genes,
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со ефект на активирање на добрите гени, оние кои спречуваат болести
02:32
turning off the disease-promoting genes.
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и деактивирање на гените кои причинуваат болест.
02:36
And so these findings I think are really very powerful,
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И јас мислам дека овие откритија се навистина моќни
02:39
giving many people new hope and new choices.
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и им даваат нова надеж и избор на многу луѓе.
02:41
And companies like Navigenics and DNA Direct and 23andMe,
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И компаниите како Navigenix и DNA Direct и 23andMe,
02:46
that are giving you your genetic profiles,
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кои ви ги даваат вашите генетски профили,
02:49
are giving some people a sense of, "Gosh, well, what can I do about it?"
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им даваат на некои луѓе мисли како "Хм, па што би можел јас да сторам за ова?"
02:52
Well, our genes are not our fate, and if we make these changes --
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Па, нашите гени не се навистина наша судбина, и ако ги направиме овие промени --
02:55
they're a predisposition -- but if we make bigger changes
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тие се предиспозиција, но ако направиме поголеми промени
02:57
than we might have made otherwise,
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отколку што би направиле во други околности,
02:59
we can actually change how our genes are expressed.
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ние всушност можеме да го промениме начинит на експресирање на нашите гени.
03:02
Thank you.
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Ви благодарам.
03:03
(Applause)
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(Аплауз)
Translated by Zvezdana Moneva
Reviewed by Boris Stefanovski

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ABOUT THE SPEAKER
Dean Ornish - Physician, author
Dean Ornish is a clinical professor at UCSF and founder of the Preventive Medicine Research Institute. He's a leading expert on fighting illness -- particularly heart disease with dietary and lifestyle changes.

Why you should listen

Dr. Dean Ornish wants you to live longer, and have more fun while you're at it. He's one of the leading voices in the medical community promoting a balanced, holistic approach to health, and proving that it works. The author of Eat More, Weigh Less and several other best-selling books, Ornish is best known for his lifestyle-based approach to fighting heart disease.

His research at the Preventive Medicine Research Institute (the nonprofit he founded) clinically demonstrated that cardiovascular illnesses -- and, most recently prostate cancer -- can be treated and even reversed through diet and exercise. These findings (once thought to be physiologically implausible) have been widely chronicled in the US media, including Newsweek, for which Ornish writes a column. The fifty-something physician, who's received many honors and awards, was chosen by LIFE Magazine as one of the most influential members of his generation. Among his many pursuits, Ornish is now working with food corporations to help stop America's obesity pandemic from spreading around the globe.

More profile about the speaker
Dean Ornish | Speaker | TED.com

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