Sandrine Thuret: You can grow new brain cells. Here's how
Sandrin Ture (Sandrine Thuret): Možete proizvoditi nove moždane ćelije. Evo kako
Sandrine Thuret studies the way adult brains create new nerve cells in the hippocampus -- a brain area involved in memory and mood. Full bio
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da proizvodimo nove nervne ćelije?
about that question,
prilično nova oblast istraživanja.
sa jednim svojim kolegom, Robertom,
to one of my colleagues, Robert,
they are cured of their cancer
kojima je rečeno da su izlečeni od raka
that makes sense.
that stops the cancer cells multiplying
da se ćelije raka umnožavaju,
being generated in their brain."
stvaraju u njihovom mozgu.“
like I was crazy and said,
kao da sam luda i rekao:
"Well actually, we do."
„Pa, zapravo, proizvodimo.“
that we call neurogenesis.
he was not taught what we know now --
nisu ga učili onome što sada znamo -
can generate new nerve cells.
da proizvede nove nervne ćelije.
being the good doctor that he is,
budući da je dobar doktor,
a little bit better.
parts of the brain
in the center of the brain.
u središtu mozga.
for very long,
memory, mood and emotion.
raspoloženje i emocije.
have learned more recently
structures of the adult brain
mozga odraslih osoba
označeno plavom bojom,
in an adult mouse brain.
u mozgu odraslog miša.
from the Karolinska Institutet,
sa Instituta Karolinska
700 new neurons per day
700 novih neurona dnevno
of neurons we have.
neurona koje imamo.
we were born with in that structure
sa kojima smo rođeni u toj strukturi
and what are their functions?
i koje su njihove funkcije?
for learning and memory.
za učenje i pamćenje.
of the adult brain
mozga odrasle osobe
izvesne sposobnosti pamćenja.
za prostorno prepoznavanje -
for spatial recognition --
your way in the city.
dok idete po gradu.
for memory capacity,
to add time to our memory
pridodalo vreme
very similar memories, like:
veoma sličnih sećanja, na primer:
every day in the same area,
svakoga dana u istom području,
to my colleague Robert
on neurogenesis and depression.
u vezi sa neurogenezom i depresijom.
a lower level of neurogenesis.
of these newborn neurons,
novih neurona
the symptoms of depression,
between neurogenesis and depression.
između neurogeneze i depresije.
just block neurogenesis,
of the antidepressant.
were suffering from depression
patili od depresije
newborn neurons from being generated.
stvaranje novih neurona,
to generate new neurons
da bi se proizveli novi neuroni
we have enough evidence
da imamo dovoljno dokaza
is a target of choice
da je neurogeneza ciljana meta
memory formation or mood,
pamćenje ili raspoloženje,
associated with aging,
vezano za starost,
of behaviors and activities,
they will increase neurogenesis
da će pojačati neurogenezu
of these new neurons.
novih neurona.
of new neurons in the hippocampus.
novih neurona u hipokampusu.
the production of new neurons.
proizvodnju novih neurona.
leading to sleep deprivation.
will decrease as we get older,
Rusty Gage from the Salk Institute,
Rasti Gejdž sa Instituta Solk,
can have an impact
of the hippocampus of a mouse
u svom kavezu.
are actually newborn neurons-to-be.
su zapravo budući novi neuroni,
of the hippocampus of a mouse
u svom kavezu.
the new neurons-to-be.
buduće nove neurone.
but that's not all.
na neurogenezu, ali to nije sve.
in the hippocampus.
u hipokampusu.
to have efficacy.
da su delotvorne.
to point a few out to you:
will increase neurogenesis.
od 20 do 30 odsto povećaće neurogenezu.
pravljenje razmaka između obroka,
spacing the time between your meals --
in dark chocolate or blueberries,
of these new neurons.
in high saturated fat
bogat visokozasićenim mastima
on neurogenesis.
will decrease neurogenesis.
će smanjiti neurogenezu.
contained in red wine,
the survival of these new neurons.
kako se pokazalo.
kada budete večerali na proslavi,
"neurogenesis-neutral" drink.
da posegnete za ovim pićem
let me point out the last one --
na poslednju stvar, pomalo čudnu.
with food textures,
teksturom hrane
soft diet impairs neurogenesis,
zapravo narušava neurogenezu,
mastication -- chewing -- or crunchy food.
mastikaciju, žvakanje, ili hrskave hrane.
at the cellular level,
na nivou ćelije,
životinjskih modela.
to human participants,
i ljudima učesnicima
the diet modulates memory and mood
menja pamćenje i raspoloženje
as it modulates neurogenesis,
will improve memory capacity,
će poboljšati kapacitet memorije,
symptoms of depression --
pogoršati simptome depresije,
which increase neurogenesis,
koje povećavaju neurogenezu
the symptoms of depression.
simptoma depresije.
pamćenje i raspoloženje
of the new neurons in the hippocampus.
novih neurona u hipokampusu.
of the food, when you eat it
interested in neurogenesis --
zainteresovanih za neurogenezu,
the function of these new neurons,
funkcije tih novih neurona
and their production.
njihov opstanak i njihovu proizvodnju.
the neurogenesis of Robert's patients.
Robertovih pacijenata.
of your neurogenesis.
za svoju neurogenezu.
Fantastično istraživanje, Sandrin.
Fantastic research, Sandrine.
da si mi promenila život -
in the running thing.
about aerobic exercise,
samo o aerobnim vežbama,
bilo kakvo energično vežbanje?
if it's just the running itself,
da li je to do samog trčanja,
will increase the production --
što zaista povećava proizvodnju,
točak za trčanje za kancelariju?
a running wheel in my office?
ABOUT THE SPEAKER
Sandrine Thuret - Neural stem cell researcherSandrine Thuret studies the way adult brains create new nerve cells in the hippocampus -- a brain area involved in memory and mood.
Why you should listen
In her lab at King's College London, Sandrine Thuret studies adult neurogenesis -- the process by which adult brains create new nerve cells. (Until the 1990s, we didn't even know they did this!)
Thuret's work focuses on the hippocampus, the area of the brain that is related to memory, and her work asks two big questions: How can we help our healthy brains create new nerve cells throughout our lives, through diet and behavior changes? And how can we study the effects of diseases such as depression and Alzheimer's on our brains' ability to grow?
Sandrine Thuret | Speaker | TED.com